Dengue and hantavirus coinfection with good outcomes: a clinical case from Panama

2021 ◽  
Vol 14 (5) ◽  
pp. e235779
Author(s):  
Virginia Núñez-Samudio ◽  
Martín Meza ◽  
Iván Landires
Keyword(s):  
Intensive Care ◽  
Case Report ◽  
Dengue Virus ◽  
Central America ◽  
Clinical Case ◽  
Correct Diagnosis ◽  
Clinical Manifestations ◽  
Hantavirus Pulmonary Syndrome ◽  
Documented Case ◽  
Central Panama

Dengue and hantavirus are endemic in central Panama. We present a case report of a patient coinfected with dengue and hantavirus who presented overlapping clinical manifestations of both infections. The patient did not require intensive care—as it is commonplace during hantavirus pulmonary syndrome—and he had a good outcome. Patient’s care was positively impacted due to correct diagnosis of coinfection. This case highlights that in endemic areas, coinfection with dengue virus and hantavirus should be suspected. To the best of our knowledge, this case is the first documented case of coinfection with dengue virus and hantavirus in Central America.

scholarly journals Case report of von willebrand disease after tonsillotomy and adenotomy in a child

2021 ◽  
Vol 20 (1) ◽  
pp. 89-92
Author(s):  
S. S. Makhmudov ◽  
◽  
A. A. Ochilzoda ◽  
F. P. Dzhamolov ◽  
A. Z. Mutalibov ◽  
...  
Keyword(s):  
Case Report ◽  
Clinical Practice ◽  
Surgical Treatment ◽  
Clinical Case ◽  
Clinical Manifestations ◽  
Von Willebrand Disease ◽  
Rare Occurrence ◽  
Von Willebrand

The authors present a clinical case of von Willebrand disease detected after tonsillotomy and adenotomy in a child. The peculiarity of this observation lies in the rare occurrence of von Willebrand disease in clinical practice, as well as the manifestation of the clinical manifestations of this pathology against the background of surgical treatment in a child.

scholarly journals Grover’s disease in a patient with atopic dermatitis - a case report

2021 ◽  
Vol 74 (1-2) ◽  
pp. 33-37
Author(s):  
Sanja Jakovljevic ◽  
Ljuba Vujanovic ◽  
Dejan Ogorelica ◽  
Aleksandra Fejsa-Levakov ◽  
Jasmina Sekulic
Keyword(s):  
Case Report ◽  
Immunoglobulin E ◽  
Histopathological Examination ◽  
Correct Diagnosis ◽  
Elevated Serum ◽  
Clinical Manifestations ◽  
Skin Lesions ◽  
Complete Regression ◽  
Laboratory Findings ◽  
Topical Corticosteroids

Introduction. Grover?s disease is characterized by pruriginous polymorphic rash with a variable course and duration. Although the etiology is still unknown, the disease is often associated with other dermatoses, malignant diseases, use of certain medications, as well as immunosuppression. Case Report. We report a case of a 70-year-old male patient who was referred for examination to the Clinic of Dermatovenereology Diseases, Clinical Center of Vojvodina, due to a rash that lasted for nine months. The first lesions on the skin appeared around the nipples as exudative eczematous plaques. A few months later, identical lesions appeared on the lower legs. During treatment with systemic antihistamines and topical corticosteroids, there were episodes of transient improvements and re-exacerbations. In the meantime, erythematous brownish, round and oval papules appeared on the abdomen and the back, accompanied by intense itch. Laboratory findings revealed eosinophilia and elevated serum immunoglobulin E levels. A skin biopsy of the back lesion was performed and the histopathological examination confirmed the diagnosis of Grover?s disease. After the systemic treatment using corticosteroids and antihistamines, with gradual dose reduction and application of topical corticosteroids and emollients, complete regression of the skin lesions was achieved. Conclusion. Since the clinical manifestations of the disease may be nonspecific and discrete, dermatopathological analysis is of crucial importance in making the correct diagnosis. In patients with atopy, the treatment with systemic corticosteroids, antihistamines and topical agents may lead to regression of skin lesions with a significant improvement in the quality of life.

scholarly journals CLINICAL CASE OF THE SUCCESSFUL TREATMENT OF AN ACUTE ETHYLENE GLYCOL POISONING

2020 ◽  
Vol 25 (3) ◽  
pp. 28-34
Author(s):  
Sergei Anatolievich Vasilyev ◽  
◽  
Oleg Anatolievich Kuznetsov ◽  
Pavel Pavlovich Gavrikov ◽  
Milena Andreevna Formozova ◽  
...  
Keyword(s):  
Intensive Care ◽  
Respiratory Failure ◽  
Ethylene Glycol ◽  
Successful Treatment ◽  
Clinical Case ◽  
Lethal Dose ◽  
Clinical Manifestations ◽  
Toxic Encephalopathy ◽  
Toxic Impact ◽  
Ethylene Glycol Poisoning

In clinical case of toxic impact by ethylene glycol with severe development of acute kidney damage, respiratory failure and toxic encephalopathy, dynamic of clinical manifestations against the background of intensive care with a positive expected result of treatment in a patient who took a dose of ethylene glycol exceeding the lethal dose by 5 times is reflected.

scholarly journals Rare dermatological diseases: Devergie disease

2020 ◽  
Vol 22 (7) ◽  
pp. 54-56
Author(s):  
Kristina T. Plieva ◽  
◽  
Elena V. Denisova ◽  
Maksim A. Bobrov ◽  
Dzerassa R. Mildzikhova ◽  
...  
Keyword(s):  
Key Words ◽  
Rare Disease ◽  
Histological Examination ◽  
Clinical Case ◽  
Correct Diagnosis ◽  
Clinical Manifestations ◽  
Dermatological Diseases ◽  
Pityriasis Rubra Pilaris

Devergie disease, or pityriasis rubra pilaris, is a poorly studied and rare disease, which prevalence is estimated at about 1 in 400 thousand. The article provides relevant data on the classification of Devergie disease, features of the course and clinical manifestations of each of the 6 types of the disease, as well as the ap-proximate occurrence of these types. Erythroderma can occur in Devergie disease, but data on the incidence of this manifestation vary significantly. The article presents a clinical case of type 1 Devergie disease. This case is of particular interest, since the disease began not according to the classical scheme, i.e., with appearance of an erythematous spot, but with extensive areas of erythroderma. This case is intended to draw attention to the fact that dermatological diseases do not always develop in a typical way, and the correct diagnosis often requires a histological examination. Key words: pityriasis rubra pilaris, Devergie disease, erythroderma, clinical case. For citation: Plieva K.T., Denisova E.V., Bobrov M.A. et al. Rare dermatological diseases: Devergie disease. Consilium Medicum. 2020; 22 (7): 54–56. DOI: 10.26442/20751753.2020.7.200187

scholarly journals Rapidly progressive course of nonspecific aortoarteritis: a clinical case

2020 ◽  
Vol 11 (4) ◽  
pp. 83-89
Author(s):  
Marina V. Grushina ◽  
Ilya Sergeevich Grekov ◽  
Kseniya D. Arkhypova
Keyword(s):  
Cerebral Ischemia ◽  
Arterial Hypertension ◽  
Clinical Case ◽  
Carotid Arteries ◽  
Correct Diagnosis ◽  
Clinical Manifestations ◽  
Practical Interest ◽  
Diagnostic Errors ◽  
Vascular Lesions ◽  
First Year

Background. Nonspecific aortoarteritis, or Takayasus disease, is one of the most complex and rare pathologies in modern clinical practice. It is the orphan nature of the disease, along with non-specific clinical manifestations, that causes a large number of clinical and diagnostic errors that lead to an unfavorable prognosis and early disability of patients. Despite the development of modern methods of treatment of nonspecific aortoarteritis, in some cases it is not possible to achieve a stable remission, which leads to a steady progression of the pathological process. Clinical case description. The article presents a case of a rapidly progressing course of Takayasu's disease in a young woman with multiple arterial vascular lesions that developed during the first year after the onset of arterial hypertension, while the narrowing of the carotid arteries (7585%) was not accompanied by signs of cerebral ischemia. The follow-up period was 10 years. Conclusion. Given the peculiarities of this nosology, each identified case of Takayasus disease is of great clinical and practical interest. The disease peculiarity in thise patient is that during the first year from the onset of arterial hypertension, the main occlusive lesions of the aorta and arterial vessels were identified. At the same time, the narrowing of the carotid arteries (7585%) was not accompanied by signs of cerebral ischemia. It should be noted that often the symptoms of non-specific aortoarteritis appear under the masks of other diseases, which requires a careful differential search. A correct diagnosis and timely treatment can prevent the development of complications and slow the progression of the disease.

scholarly journals Sodium fluoracetate's poisoning: A case report

2020 ◽  
Vol 26 (2) ◽  
Author(s):  
Diana Ávila Reyes ◽  
Juan Camilo Galvis Mejía ◽  
Jose Fernando Gómez González ◽  
Mateo Aguirre Flórez
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Case Report ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Lethal Dose ◽  
Clinical Manifestations ◽  
Timely Manner ◽  
Satisfactory Outcome ◽  
Cardinal Symptom

  Introduction: Sodium fluoroacetate, known as compound 1080, was discovered in Germany during the Second World War. It is usually used as a rodenticide, it is an odorless and tasteless substance, with a lethal dose in humans of 2 mg / kg that is why it was withdrawn from the market in some countries, including Colombia; however, it is obtained illegally. This substance has biochemical and physiological effects at the cellular level that alter the transport of citrate at the mitochondrial level, generating accumulation of lactic acid and alteration of the glucose use. The clinical manifestations are nonspecific since there is no any cardinal symptom. Therefore, its diagnosis is made due to high clinical suspicion associated with establishment of exposure to the compound in view of the difficulty to obtain paraclinical confirmation in a timely manner. Methods: We present a case report of intentional ingestion of sodium fluoroacetate in an adolescent that is associated with an infection added to the bloodstream by methicillin- sensitive Staphylococcus aureus (MSSA). The patient developed multiple complications that lead to support in the Intensive Care Unit (ICU) with a satisfactory outcome. In view of the lack of a specific antidote, she was treated with ethanol in order to increase the level of acetate; thus, offering an alternative substrate to the Krebs cycle. It is suggested that the ethanol offers benefits in the acute treatment of these patients. Results: The patient with sodium fluoroacetate poisoning and kidney failure received renal replacement therapy with a favorable evolution and survival at discharge from the intensive care unit of a third-level hospital in the city of Pereira, Risaralda, Colombia. Conclusions: Sodium fluoroacetate poisoning is relatively rare and can cause acute kidney injury and multi-organ failure with a high rate of complications and death. A case of self-inflicted poisoning that received a timely manner continuous renal replacement therapy with a favorable outcome in terms of ICU survival was presented.

scholarly journals MESENCHYMAL TUMORS OF THE COLON AND RECTUM: DIAGNOSIS, TREATMENT, PROGNOSIS (case report and review)

2020 ◽  
Vol 19 (3) ◽  
pp. 97-112
Author(s):  
O. A. Mainovskaya ◽  
M. A. Tarasov ◽  
E. M. Romanova ◽  
S. V. Chernyshov
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Clinical Case ◽  
Clinical Manifestations ◽  
Mesenchymal Tumor ◽  
Mesenchymal Tumors ◽  
Different Types ◽  
Colon And Rectum ◽  
Treatment Prognosis ◽  
Derivatives Of

Mesenchymal tumors of the colon and rectum are extremely rare and do not have specific clinical manifestations, their diagnosis and staging cause certain difficulties.Different types of mesenchymal tumors differ in prognosis and choice of the treatment. It explains the importance of differential diagnosis of these neoplasms among themselves and tumors-derivatives of other embryonic structures.The article describes the clinical case of a rare mesenchymal tumor and management of the patient.

scholarly journals A complex case of diagnosis of Conn’s syndrome

2020 ◽  
Vol 28 (1) ◽  
pp. 67-72
Author(s):  
Grigory A. Ignatenko ◽  
Ilya S. Grekov ◽  
Marina V. Grushina ◽  
Anna V. Dubovyk
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Clinical Case ◽  
Correct Diagnosis ◽  
Clinical Manifestations ◽  
The Other ◽  
Primary Hyperaldosteronism ◽  
Complex Case ◽  
Conn’S Syndrome ◽  
The Given

The primary hyperaldosteronism also known as Conns syndrome, is a rarely diagnosed disease that commonly runs under a mask of ischemic heart disease and the primary arteria hypertension (AH). Nevertheless, the incidence of the given pathology among all patients with AH makes almost 17%. On the other hand, the absence of specific clinical manifestations of the disease makes its timely and correct diagnosis difficult which is fraught with serious complications. In the article a clinical case of Conns syndrome and peculiarities of its diagnosis are described.

scholarly journals Hemorrhagic thrombocytopathy with defective signal transduction CalDAG-GEFI

2021 ◽  
Vol 20 (3) ◽  
pp. 126-131
Author(s):  
A. O. Koposova ◽  
D. V. Fedorova ◽  
A. V. Pshonkin ◽  
A. V. Poletaev ◽  
E. A. Seregina ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Case Report ◽  
Rare Disease ◽  
Clinical Case ◽  
Clinical Manifestations ◽  
The World ◽  
The Moment

Hemorrhagic thrombocytopathy with defective signal transduction CalDAG-GEFI is a rare disease associated with a mutation in the RASGRP2 gene. At the moment, this disease is described in 10 person in the world. We present clinical case report of this pathology of a 9-year-old child. We also offer a review of the available literature about pathogenetic features, clinical manifestations and prevalence of this rare disease. The patient’s parents gave their consent to the use of their child’s data, including photographs, for research purposes and in publications.

scholarly journals Hepatic fascioliasis: case report and review

1996 ◽  
Vol 38 (1) ◽  
pp. 69-73 ◽  
Author(s):  
Salha Abdul-Hadi ◽  
Rosa Contretas ◽  
Claudio Tombazzi ◽  
Marta Alvarez ◽  
Maribel Melendez
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Side Effects ◽  
Clinical Manifestations ◽  
Documented Case ◽  
Human Fascioliasis ◽  
Oral Doses

A well documented case of hepatic fascioliasis (HF), successfully treated with triclabendazole, is reported. Predominant clinical manifestations were fever, marked eosinophilia and abdominal pain. Triclabendazole was given as two single oral doses of 10 mg/kg each. Neither side effects nor clinical or parasitological relapses were seen after three months of follow up Based on this experience and few other similar reports in the literature, triclabendazole might be a valid therapeutical alternative in the treatment of human fascioliasis.

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