Rapid resolution of symptoms and signs of intracerebral haemorrhage: case reports

Brain tumors can present with various psychiatric symptoms, with or without neurological symptoms, an aspect that complicates the clinical picture. However, no systematic description of symptoms that should prompt a neurological investigation has been provided. This review aims to summarize available case reports describing patients with brain tumors showing psychiatric symptoms before brain tumor diagnosis, in order to provide a comprehensive description of these symptoms as well as their potential relationship with delay in the diagnosis. A systematic literature review on case reports of brain tumors and psychiatric symptoms from 1970 to 2020 was conducted on PubMed, Ovid, Psych Info, and MEDLINE. Exclusion criteria comprised tumors not included in the World Health Organization (WHO) Classification 4th edition and cases in which psychiatric symptoms were absent or followed the diagnosis. A total of 165 case reports were analyzed. In a subset of patients with brain tumors, psychiatric symptoms can be the only manifestation or precede focal neurological signs by months or even years. The appearance of focal or generalized neurological symptoms after, rather than along with, psychiatric symptoms was associated with a significant delay in the diagnosis in adults. A timely assessment of psychiatric symptoms might help to improve early diagnosis of brain tumors.

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Acute Pancreatitis: An Atypical Presentation

Case Reports in Gastroenterology ◽

10.1159/000475920 ◽

2017 ◽

Vol 11 (2) ◽

pp. 359-363 ◽

Cited By ~ 1

Author(s):

Omar Nadhem ◽

Omar Salh

Keyword(s):

Acute Pancreatitis ◽

Abdominal Pain ◽

Case Reports ◽

Case Series ◽

Normal Serum ◽

Intravenous Fluids ◽

Serum Enzyme ◽

Serum Lipase ◽

Upper Abdominal ◽

Symptoms And Signs

Acute pancreatitis is an important cause of acute upper abdominal pain. Because its clinical features are similar to a number of other acute illnesses, it is difficult to make a diagnosis only on the basis of symptoms and signs. The diagnosis of acute pancreatitis is based on 2 of the following 3 criteria: (1) abdominal pain consistent with pancreatitis, (2) serum lipase and/or amylase ≥3 times the upper limit of normal, and (3) characteristic findings from abdominal imaging. The sensitivity and specificity of lipase in diagnosing acute pancreatitis are undisputed. However, normal lipase level should not exclude a pancreatitis diagnosis. In patients with atypical pancreatitis presentation, imaging is needed. We experienced two cases of acute pancreatitis associated with normal serum enzyme levels. Both patients were diagnosed based on clinical and radiological evidence. They were successfully treated with intravenous fluids and analgesics with clinical and laboratory improvement. The importance of this case series is the unlikely presentation of acute pancreatitis. We believe that more research is needed to determine the exact proportion of acute pancreatitis patients who first present with normal serum lipase, since similar cases have been seen in case reports.

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A Rare Case of Bilateral Spontaneous Intracerebral Haemorrhage Presenting With Left Hemiplegia: A Case Report

Indian Journal of Physical Medicine and Rehabilitation ◽

10.5005/ijopmr-26-4-109 ◽

2015 ◽

Vol 26 (4) ◽

pp. 109-110

Author(s):

AK Joy ◽

Annada Sankar Mohes ◽

Th Bidyarani ◽

L Dorendrojit Singh ◽

Aten Jongky

Keyword(s):

Case Report ◽

Basal Ganglia ◽

Intracerebral Haemorrhage ◽

Vascular Malformation ◽

Rare Case ◽

Case Reports ◽

Cranial Nerve Involvement ◽

12Th Cranial Nerve ◽

Contrast Ct ◽

Spontaneous Intracerebral Haemorrhage

Abstract Haemorrhage is responsible for around 11% of stroke syndrome. Haemorrhage usually occurs at a single site. However, it can be at multiple sites in some specific conditions i.e. coagulopathy, vascular malformation, malignancy etc. A 56-year-old male with left sided hemiplegia was admitted in the rehabilitation ward of RIMS, Imphal. He was hypertensive and was on irregular medication for that. He was also an alcoholic and chronic smoker for last 20 years. Patient was conscious and clinical examination revealed left 7th and 12th cranial nerve involvement with left hemiplegia. Non-contrast CT scan of brain revealed right thalamus and left basal ganglia haemorrhages. Thorough history and investigations did not reveal any aetiology for bilateral haemorrhage. Patient was treated with conservative management and improvement was noticed in serial follow-ups. There are very few case reports about bilateral spontaneous intracerebral haemorrhage associated with other diseases like migraine, Japanese encephalitis etc. Cause of bilateral haemorrhage in our case is doubtful.

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Clozapine-induced liver injury and pleural effusion

Mental Illness ◽

10.1108/mi.2014.5403 ◽

2014 ◽

Vol 6 (2) ◽

pp. 36-37

Author(s):

Joseph P.M. Kane ◽

Francis A. O'Neill

Keyword(s):

Pleural Effusion ◽

Liver Injury ◽

Liver Enzymes ◽

Clinical Symptoms ◽

Acute Liver Injury ◽

Case Reports ◽

High Index ◽

Documented Case ◽

High Index Of Suspicion ◽

Symptoms And Signs

Clozapine, whilst associated commonly with a transient and benign increase in liver enzymes, has also been associated with varying presentations of hepatitis in existing case reports. This report describes what we believe to be the first documented case of acute liver injury and pleural effusion associated with clozapine, resolving after cessation of the agent. The case supports existing literature in advocating a high index of suspicion, particularly in the 4-5 weeks following clozapine initiation, when considering nonspecific clinical symptoms and signs.

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Rapid resolution of severe subcutaneous emphysema causing respiratory failure with subcutaneous drain

SAGE Open Medical Case Reports ◽

10.1177/2050313x21997196 ◽

2021 ◽

Vol 9 ◽

pp. 2050313X2199719

Author(s):

Ala Mustafa ◽

Caio Heleno ◽

Douglas T Summerfield

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Respiratory Failure ◽

Respiratory Distress ◽

Critically Ill ◽

Subcutaneous Emphysema ◽

Case Reports ◽

Definitive Treatment ◽

Critically Ill Patient ◽

Rapid Resolution

This case reports on a critically ill patient (Male, 74) with severe subcutaneous emphysema which progressed to causing respiratory distress. We document both the severity of the condition we observed and then present a novel intervention. In this case, we decompressed the patient at the intensive care unit-bedside and resolved the condition. While subcutaneous emphysema is relatively common, the severity of the condition we observed, and the lack of definitive treatment guidance have prompted us to present this case as a plausible treatment guide.

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Cysticercosis and taeniasis cases diagnosed at two referral medical institutions, Belgium, 1990 to 2015

Eurosurveillance ◽

10.2807/1560-7917.es.2019.24.35.1800589 ◽

2019 ◽

Vol 24 (35) ◽

Cited By ~ 1

Author(s):

Veronique Dermauw ◽

Steven Van Den Broucke ◽

Lieselotte Van Bockstal ◽

Leon Luyten ◽

Kim Luyckx ◽

...

Keyword(s):

Case Reports ◽

Grey Literature ◽

Taenia Solium ◽

Travel Information ◽

Medical Institutions ◽

Medical Facilities ◽

Beef Tapeworm ◽

Human Infections ◽

Available Information ◽

Symptoms And Signs

Background Few case reports on human infections with the beef tapeworm Taenia saginata and the pork tapeworm, Taenia solium, diagnosed in Belgium have been published, yet the grey literature suggests a higher number of cases. Aim To identify and describe cases of taeniasis and cysticercosis diagnosed at two Belgian referral medical institutions from 1990 to 2015. Methods In this observational study we retrospectively gathered data on taeniasis and cysticercosis cases by screening laboratory, medical record databases as well a uniform hospital discharge dataset. Results A total of 221 confirmed taeniasis cases were identified. All cases for whom the causative species could be determined (170/221, 76.9%) were found to be T. saginata infections. Of those with available information, 40.0% were asymptomatic (26/65), 15.4% reported diarrhoea (10/65), 9.2% reported anal discomfort (6/65) and 15.7% acquired the infection in Belgium (11/70). Five definitive and six probable cases of neurocysticercosis (NCC), and two cases of non-central nervous system cysticercosis (non-CNS CC) were identified. Common symptoms and signs in five of the definitive and probable NCC cases were epilepsy, headaches and/or other neurological disorders. Travel information was available for 10 of the 13 NCC and non-CNS CC cases; two were Belgians travelling to and eight were immigrants or visitors travelling from endemic areas. Conclusions The current study indicates that a non-negligible number of taeniasis cases visit Belgian medical facilities, and that cysticercosis is occasionally diagnosed in international travellers.

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An acquired acute methemoglobinemia from dietary sources: Case reports and literature review

Emergency Care Journal ◽

10.4081/ecj.2021.9089 ◽

2021 ◽

Vol 17 (1) ◽

Author(s):

Angela Mauro ◽

Iolanda Parente ◽

Thailjlia Gagliardo ◽

Anna Bonadies ◽

Raffaele Mancusi ◽

...

Keyword(s):

Literature Review ◽

Healthy Child ◽

Case Reports ◽

Sudden Onset ◽

Chemical Substances ◽

Respiratory Problems ◽

Symptoms And Signs ◽

Oxidative State

Methemoglobinemia is an alteration of the oxidative state of hemoglobin. When methemoglobin values rise above 10%, the symptoms and signs related to this condition appear, such as cyanosis, respiratory problems, fatigue and headache. Acquired methemoglobinemia is characterized by the sudden onset of cyanosis in a previous healthy child, which can be due to exposure to medications or chemical substances including nitrates, copper, sulfates, chlorites, chloramines and chlorates which can be present in food and water. We illustrate two cases of acquired methemoglobinemia related to nitrate ingestion from a vegetable source.

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Allgrove syndrome and motor neuron disease

Neurology International ◽

10.4081/ni.2018.7436 ◽

2018 ◽

Vol 10 (2) ◽

Cited By ~ 4

Author(s):

Marcos R.G. De Freitas ◽

Marco Orsini ◽

Alexandra Prufer de Queiroz Campos Araújo ◽

Luiz João Abraão Jr. ◽

Gilberto Miranda Barbosa ◽

...

Keyword(s):

Motor Neuron ◽

Motor Neuron Disease ◽

Case Reports ◽

Symptomatic Treatment ◽

Allgrove Syndrome ◽

Pathogenic Variants ◽

Aaas Gene ◽

The Subject ◽

Slow Evolution ◽

Symptoms And Signs

Allgrove or triple A syndrome (AS or AAA) is a rare autosomal recessive syndrome with variable phenotype due to mutations in AAAS gene which encodes a protein called ALADIN. Generally, it’s characterized by of adrenal insufficiency in consequence of adrenocorticotropic hormone (ACTH) resistance, besides of achalasia, and alacrimia. Neurologic features are varied and have been the subject of several case reports and reviews. A few cases of Allgrove syndrome with motor neuron disease have been already described. A 25-year-old white man, at the age of four, presented slowly progressive distal amyotrophy and weakness, autonomic dysfunction, dysphagia and lack of tears. He suffered later of orthostatic hypotension and erectile dysfunction. He presented distal amytrophy in four limbs, tongue myofasiculations, alacrimia, hoarseness and dysphagia due to achalasia. The ENMG showed generalized denervation with normal conduction velocities. Genetic testing revealed 2 known pathogenic variants in the AAAS gene (c.938T>C and c.1144_1147delTCTG). Our case presented a distal spinal amyotrophy with slow evolution and symptoms and signs of AS with a mutation in AAAS gen. Some cases of motor neuron disease, as ours, may be due to AAS. Early diagnosis is extremely important for symptomatic treatment.

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Rapid resolution of signs of primary intracerebral haemorrhage in computed tomograms of the brain.

BMJ ◽

10.1136/bmj.295.6594.379 ◽

1987 ◽

Vol 295 (6594) ◽

pp. 379-381 ◽

Cited By ~ 40

Author(s):

M S Dennis ◽

J M Bamford ◽

A J Molyneux ◽

C P Warlow

Keyword(s):

Intracerebral Haemorrhage ◽

Rapid Resolution ◽

The Brain

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Reversible Severe Rhabdomyolysis Associated with Thyrotoxic Hypokalemic Periodic Paralysis

Case Reports in Neurology ◽

10.1159/000516771 ◽

2021 ◽

pp. 394-397

Author(s):

Praewchompoo Sathirapanya ◽

Komsai Suwanno ◽

Pornchai Sathirapanya

Keyword(s):

Creatine Kinase ◽

Family History ◽

Case Reports ◽

Specific Treatment ◽

Periodic Paralysis ◽

Hypokalemic Periodic Paralysis ◽

Gated Channel ◽

History Of ◽

Symptoms And Signs ◽

Thyrotoxic Hypokalemic Periodic Paralysis

We report a case of reversible symptomatic rhabdomyolysis associated with thyrotoxic hypokalemic periodic paralysis. The patient had neither past medical nor family history of either disorder. The presenting neurological symptoms and signs, serum potassium, and creatine kinase levels returned to normal without specific treatment. Based on previous case reports, we attributed the combination of the disorders to a mutation of the calcium-gated channel (CACN) gene and its related encoded proteins.

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