scholarly journals What factors are associated with resilient outcomes in children exposed to social adversity? A systematic review

BMJ Open ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. e024870 ◽  
Author(s):  
Deirdre Gartland ◽  
Elisha Riggs ◽  
Sumaiya Muyeen ◽  
Rebecca Giallo ◽  
Tracie O Afifi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Skills ◽  
School Factors ◽  
Community Factors ◽  
Factors Associated ◽  
Increased Risk ◽  
Starting Point ◽  
Social Adversity ◽  
Parent Loss ◽  
Child Resilience

ObjectivesChildren exposed to social adversity—hardship as a result of social circumstances such as poverty or intergenerational trauma—are at increased risk of poor outcomes across the life course. Understanding what promotes resilient outcomes is essential for the development of evidence informed intervention strategies. We conducted a systematic review to identify how child resilience is measured and what factors are associated with resilient outcomes.DesignSystematic search conducted in CINAHL, MEDLINE and PsychInfo from January 2004 to October 2018 using the keywords ‘resilien* and child* in the title or abstract. Eligible studies: (1) described children aged 5–12 years; (2) identified exposure to social adversity; (3) identified resilience; and (4) investigated factors associated with resilience.Outcome measures(1) approaches to identifying resilience and (2) factors associated with resilient outcomes.ResultsFrom 1979 studies retrieved, 30 studies met the inclusion criteria. Most studies were moderate to high quality, with low cultural competency. Social adversity exposures included poverty, parent loss, maltreatment and war. Only two studies used a measure of child resilience; neither was psychometrically validated. Remaining studies classified children as resilient if they showed positive outcomes (eg, mental health or academic achievement) despite adversity. A range of child, family, school and community factors were associated with resilient outcomes, with individual factors most commonly investigated. The best available evidence was for cognitive skills, emotion regulation, relationships with caregivers and academic engagement.ConclusionsWhile there is huge variation in the type and severity of adversity that children experience, there is some evidence that specific individual, relational and school factors are associated with resilient outcomes across a range of contexts. Such factors provide an important starting point for effective public health interventions to promote resilience and to prevent or ameliorate the immediate and long-term impacts of social adversity on children.

scholarly journals Insecticide Exposure and Risk of Asthmatic Symptoms: A Systematic Review and Meta-Analysis

Toxics ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 228
Author(s):  
Jiraporn Chittrakul ◽  
Ratana Sapbamrer ◽  
Wachiranun Sirikul
Keyword(s):  
Systematic Review ◽  
Respiratory System ◽  
Meta Analysis ◽  
Relevant Literature ◽  
Cross Sectional ◽  
Medical Opinion ◽  
Factors Associated ◽  
Insecticide Exposure ◽  
Increased Risk ◽  
The Impact

The incidence of respiratory disease is increasing. In relation to this, in addition to infection, factors associated with working with chemical insecticides are a cause for concern. Some of the chemicals involved have been shown to affect the respiratory system, and consequentially workers are at increased risk of conditions such as asthma. However, medical opinion around this area is still controversial; therefore, the objective of this study is to investigate the association between exposure to insecticides and asthma by means of a systematic review of the relevant literature. Relevant literature was identified, and a systematic review was conducted to investigate the association between exposure to insecticides and asthma. A total of five studies (three cross sectional and two cohort) including 45,435 subjects were identified as relevant. The summary odds ratios related to the impact of exposure to specific insecticides on asthma were organophosphates 1.31 (95%CI = 1.17–1.48, I2 = 27%, p = 0.172), carbamates 1.44 (95%CI 1.08–1.92, I2 = 56.7%, p = 0.031) and organochlorines 1.31 (95%CI 1.19–1.64, I2 = 37.3%, p = 0.131). Farmers exposed to certain insecticides may have an increased risk of asthma and asthmatic symptoms, but further research on that issue is urgently needed.

scholarly journals Risk factors for opioid-induced respiratory depression in surgical patients: a systematic review and meta-analyses

BMJ Open ◽  
2018 ◽  
Vol 8 (12) ◽  
pp. e024086 ◽  
Author(s):  
Kapil Gupta ◽  
Mahesh Nagappa ◽  
Arun Prasad ◽  
Lusine Abrahamyan ◽  
Jean Wong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Respiratory Depression ◽  
Meta Analysis ◽  
Sleep Apnoea ◽  
Factors Associated ◽  
Obstructive Sleep ◽  
Increased Risk ◽  
Daily Dose ◽  
Morphine Equivalent

ObjectiveThis systematic review and meta-analysis aim to evaluate the risk factors associated with postoperative opioid-induced respiratory depression (OIRD).DesignSystematic review and meta-analysis.Data sourcesPubMed-MEDLINE, MEDLINE in-process, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, PubMed and Clinicaltrials.gov (January 1946 to November 2017).Eligibility criteriaThe inclusion criteria were: (1) adult patients 18 years or older who were administered opioids after surgery and developed postoperative OIRD (OIRD group); (2) all studies which reported both OIRD events and associated risk factors; (3) all studies with reported data for each risk factor on patients with no OIRD (control group) and (4) published articles in English language.Data analysisWe used a random effects inverse variance analysis to evaluate the existing evidence of risk factors associated with OIRD. Newcastle-Ottawa scale scoring system was used to assess quality of study.ResultsTwelve observational studies were included from 8690 citations. The incidence of postoperative OIRD was 5.0 cases per 1000 anaesthetics administered (95% CI: 4.8 to 5.1; total patients: 841 424; OIRD: 4194). Eighty-five per cent of OIRD occurred within the first 24 hours postoperatively. Increased risk for OIRD was associated with pre-existing cardiac disease (OIRD vs control: 42.8% vs 29.6%; OR: 1.7; 95% CI: 1.2 to 2.5; I2: 0%; p<0.002), pulmonary disease (OIRD vs control: 17.8% vs 10.3%; OR: 2.2; 95% CI: 1.3 to 3.6; I2: 0%; p<0.001) and obstructive sleep apnoea (OIRD vs control: 17.9% vs 16.5%; OR: 1.4; 95% CI: 1.2 to 1.7; I2: 31%; p=0.0003). The morphine equivalent daily dose of the postoperative opioids was higher in the OIRD group than in the control; (24.7±14 mg vs 18.9±13.0 mg; mean difference: 2.8; 95% CI: 0.4 to 5.3; I2: 98%; p=0.02). There was no significant association between OIRD and age, gender, body mass index or American Society of Anesthesiologists physical status.ConclusionPatients with cardiac, respiratory disease and/or obstructive sleep apnoea were at increased risk for OIRD. Patients with postoperative OIRD received higher doses of morphine equivalent daily dose.

scholarly journals Prevalence Of Burnout Syndrome And Factors Associated With University Teachers

10.3823/2319 ◽  
2017 ◽  
Vol 10 ◽  
Author(s):  
Ericka Silva Holmes ◽  
Sérgio Ribeiro dos Santos ◽  
Anna Alice Figuerêdo de Almeida ◽  
Rozileide Martins Simões Candeia ◽  
Laura Cristhiane Mendonça Rezende Chaves ◽  
...  
Keyword(s):  
Systematic Review ◽  
Associated Factors ◽  
Small Variation ◽  
Burnout Syndrome ◽  
Work Overload ◽  
University Teachers ◽  
Factors Associated ◽  
Starting Point ◽  
High Employment ◽  
Selection Of

This is a systematic review that sought to identify the prevalence and factors associated with Burnout Syndrome in university teachers. The collection of the studies was done through descriptors in databases, which resulted in the selection of 8 articles. The prevalence for burnout had a small variation, but presented worrying values. The most frequent associated factors were: work overload, accumulation of activities beyond teaching, high employment ties, devaluation of the work performed and low remuneration. Burnout is still little recognized and studied in the category of university teachers, and it is difficult to identify an exact prevalence for this category. However, the associated factors are well defined and should be considered as a starting point for the prevention of the syndrome.

scholarly journals Childhood factors associated with increased risk for mood episode recurrences in bipolar disorder—A systematic review

2019 ◽  
Vol 21 (6) ◽  
pp. 483-502 ◽  
Author(s):  
Xavier Estrada‐Prat ◽  
Anna R. Van Meter ◽  
Ester Camprodon‐Rosanas ◽  
Santiago Batlle‐Vila ◽  
Benjamin I. Goldstein ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bipolar Disorder ◽  
Factors Associated ◽  
Mood Episode ◽  
Increased Risk ◽  
Childhood Factors

scholarly journals Long-term sequelae of Pneumococcal Sepsis in children: a systematic review

2021 ◽  
Author(s):  
Adeteju A Ogunbameru ◽  
Rafael N Miranda ◽  
Joanna Bielecki ◽  
Beate Sander
Keyword(s):  
Systematic Review ◽  
Prognostic Factors ◽  
Pediatric Patients ◽  
Meta Analysis ◽  
Length Of Hospital Stay ◽  
Factors Associated ◽  
Pneumococcal Sepsis ◽  
Increased Risk ◽  
Meta Analyses

Background: Long-term sequelae associated with pneumococcal sepsis (PS) in pediatric patients in existing literature is currently unclear. Aim: To review the evidence on sequelae and prognostic factors associated with PS among pediatric patients. Method: We conducted a systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting guidelines. We screened six databases from their inception to January 15, 2021. Study population were neonates, infants, children and adolescents less than 18 years old with suspected or confirmed PS disease. Outcomes included sequelae types, prognostic factors, pooled death estimate and length of hospital stay (LOS) for survivors and deceased patients. Quality of studies was assessed using Joanna Briggs Institute appraisal checklists. Results: We screened 981 abstracts, and 24 full-text articles for final review. Septic shock was the most prevalent physical sequelae reported (13%, n=1492 patients). No functional, cognitive or neurological sequelae were reported in included studies. Meta-analysis of pooled mortality estimate was 14.6% (95%CI: 9.9 -19.4%). Prognostic factors associated with increased risk of PS sequelae and death included pediatric risk of mortality score ≥ 10 and co-infection with meningitis. LOS for survivors and non-survivors ranged between 5-30 days and 1-30 days. Nine included studies met at least 50% of the quality assessment criteria. Conclusion: Physical sequelae and death are the PS sequelae types currently identified in existing literature. Lack of information about other possible sequelae types suggests the long-term consequences of PS disease maybe underreported, especially in resource-limited settings. Future studies should consider exploring reasons for the existing of this knowledge gap.

scholarly journals Preoperative prognostic factors associated with postoperative delirium in older people undergoing surgery: protocol for a systematic review and individual patient data meta-analysis

2020 ◽  
Author(s):  
Tayler A Buchan ◽  
Behnam Sadeghirad ◽  
Nayeli Schmutz ◽  
Nicolai Goettel ◽  
Farid Foroutan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Elderly Patients ◽  
Postoperative Delirium ◽  
Individual Patient Data ◽  
Elective Surgery ◽  
Meta Analysis ◽  
Patient Data ◽  
Factors Associated ◽  
Increased Risk

Abstract Background: Early identification of patients at risk for postoperative delirium is essential because adequate well-timed interventions could reduce the occurrence of delirium and the related detrimental outcomes.Methods: We will conduct a systematic review and individual patient data (IPD) meta-analysis of prognostic studies evaluating the predictive value of risk factors associated with an increased risk of postoperative delirium in elderly patients undergoing elective surgery. We will identify eligible studies through systematic search of MEDLINE, EMBASE, and CINAHL from their inception to May 2020. Eligible studies will enroll older adults (≥ 50 years) undergoing elective surgery and assess pre-operative prognostic risk factors for delirium and incidence of delirium measured by a trained individual using a validated delirium assessment tool. Pairs of reviewers will, independently and in duplicate, screen titles and abstracts of identified citations, review the full texts of potentially eligible studies. We will contact chief investigators of eligible studies requesting to share the IPD to a secured repository. We will use one-stage approach for IPD meta-analysis and will assess certainty of evidence using the GRADE approach.Discussion: Since we are using existing anonymized data, ethical approval is not required for this study. Our results can be used to guide clinical decisions about the most efficient way to prevent postoperative delirium in elderly patients.

scholarly journals Clinical, Biochemical and Genetic Variables Associated With Metabolic Syndrome in Patients With Schizophrenia Spectrum Disorders Using Second-Generation Antipsychotics: A Systematic Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Marius H. Sneller ◽  
Nini de Boer ◽  
Sophie Everaars ◽  
Max Schuurmans ◽  
Sinan Guloksuz ◽  
...  
Keyword(s):  
Systematic Review ◽  
Metabolic Syndrome ◽  
Second Generation ◽  
Genetic Factors ◽  
Schizophrenia Spectrum Disorders ◽  
Factors Associated ◽  
Schizophrenia Spectrum ◽  
Increased Risk ◽  
Second Generation Antipsychotics ◽  
Spectrum Disorders

Background: Individuals with severe mental illness experience increased morbidity and mortality compared to the general population. Adverse effects of antipsychotics, including weight gain, may contribute to the development of metabolic syndrome (MetS), which is associated with increased risks of all-cause and cardiovascular disease mortality. We aim to provide a comprehensive overview of clinical, biochemical and genetic factors associated with MetS among patients with schizophrenia spectrum disorders using second-generation antipsychotics (SGA).Methods: A literature search was performed in Pubmed and Embase to identify all cohort studies, cross-sectional studies and clinical trials investigating associations with MetS in patients with schizophrenia spectrum disorders using SGAs. We extracted and enumerated clinical, biochemical and genetic factors reported to be associated with MetS. We defined factors associated with MetS as factors being reported as associated with MetS in two or more studies.Results: 58 studies were included in this review (n = 12,123). In total, 62 factors were found to be associated with increased risk of MetS. Thirty one out of 58 studies investigated factors that were reported as associated with MetS in two or more studies. With regard to clinical factors, we found gender, higher age, concomitant use of mood stabilizers, higher baseline and current BMI, earlier SGA exposure, higher dose, longer duration of treatment, psychosis and tobacco smoking to be significantly associated with MetS. Furthermore, the biochemical factors hypo-adiponectinemia, elevated levels of C-reactive protein (CRP) and higher white blood cell (WBC) count were identified as factors associated with MetS. Among pharmacogenetic factors, the rs1414334 C-allele of the HTR2C-gene was associated with MetS in patients using SGA.Conclusion: In this systematic review investigating clinical, biochemical and genetic factors associated with MetS in patients using SGAs we found that higher age, higher baseline BMI, higher current BMI and male as well as female gender were positively associated with MetS across all antipsychotics. This study may set the stage for the application of clinical, biochemical and genetic factors to predict the risk of developing MetS in patients using SGAs. Future research is needed to determine which patients using SGAs are at risk to develop MetS in clinical practice.

scholarly journals Preoperative prognostic factors associated with postoperative delirium in older people undergoing surgery: protocol for a systematic review and individual patient data meta-analysis

2020 ◽  
Author(s):  
Tayler A Buchan ◽  
Behnam Sadeghirad ◽  
Nayeli Schmutz ◽  
Nicolai Goettel ◽  
Farid Foroutan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Systematic Review ◽  
Elderly Patients ◽  
Postoperative Delirium ◽  
Individual Patient Data ◽  
Elective Surgery ◽  
Meta Analysis ◽  
Patient Data ◽  
Factors Associated ◽  
Increased Risk

Abstract Background: Early identification of patients at risk for postoperative delirium is essential because adequate well-timed interventions could reduce the occurrence of delirium and the related detrimental outcomes.Methods: We will conduct a systematic review and individual patient data (IPD) meta-analysis of prognostic studies evaluating the predictive value of risk factors associated with an increased risk of postoperative delirium in elderly patients undergoing elective surgery. We will identify eligible studies through systematic search of MEDLINE, EMBASE, and CINAHL from their inception to May 2020. Eligible studies will enroll older adults (³ 50 years) undergoing elective surgery and assess pre-operative prognostic risk factors for delirium and incidence of delirium measured by a trained individual using a validated delirium assessment tool. Pairs of reviewers will, independently and in duplicate, screen titles and abstracts of identified citations, review the full texts of potentially eligible studies. We will contact chief investigators of eligible studies requesting to share the IPD to a secured repository. We will use one-stage approach for IPD meta-analysis and will assess certainty of evidence using the GRADE approach.Discussion: Since we are using existing anonymized data, ethical approval is not required for this study. Our results can be used to guide clinical decisions about the most efficient way to prevent postoperative delirium in elderly patients. Systematic review registration: CRD42020171366

scholarly journals Sociocultural values, attitudes and risk factors associated with adolescent cyberbullying in East Asia: A systematic review

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Miriam Sang-Ah Park ◽  
Karen Jennifer Golden ◽  
Samuel Vizcaino-Vickers ◽  
Dung Jidong ◽  
Sanjana Raj
Keyword(s):  
Systematic Review ◽  
East Asia ◽  
Digital Media ◽  
Peer Pressure ◽  
Well Being ◽  
School Factors ◽  
Media Communication ◽  
Factors Associated ◽  
Urban Rural ◽  
Context Specific

Cyberbullying amongst adolescents is a rapidly growing and alarming global phenomenon that can significantly harm their well-being. Studying cyberbullying in East Asia is especially important, where peer pressure based on collectivistic ideals and rigid cultural scripts for social interactions remain strong. Furthermore, the countries represented in this review are amongst the top globally for internet usage, suggesting that adolescents in East Asia are likely to be excessive users of social media communication and be more exposed to various forms of cyberbullying. This systematic review summarizes findings from peer-reviewed journal articles and book chapters on cyberbullying amongst adolescents between the ages of 10 and 19 in East Asian countries (N = 21). SCOPUS, Google Scholar, and PsycINFO databases were searched for relevant work published between 2008 and 2020. Search strategies involved using keywords related to cyberbullying, adolescents, East Asia, and the name of each country represented in the region (China, South Korea, Japan, Hong Kong and Taiwan). Key factors associated with cyberbullying specific to adolescents in this region are identified and discussed in this review, such as gender socialization patterns and literacy with digital media communication, emphasis on academic achievement and school factors, urban-rural digital divide, relationship with parents and teachers, and collectivistic values. The present review highlights the need to pay further attention to the sociocultural context in future cyberbullying research and calls for more context-specific cyberbullying prevention programs and awareness initiatives.

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