scholarly journals Qualitative analysis of stakeholder interviews to identify the barriers and facilitators to the adoption of point-of-care diagnostic tests in the UK

BMJ Open ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. e042944
Author(s):  
Jeremy R Huddy ◽  
Melody Zhifang Ni ◽  
James Barlow ◽  
George B Hanna

ObjectivesThis study investigated the barriers and facilitators to the adoption of point-of-care tests (POCTs).DesignQualitative study incorporating a constant comparative analysis of stakeholder responses to a series of interviews undertaken to design the Point-of-Care Key Evidence Tool.SettingThe study was conducted in relation to POCTs used in all aspects of healthcare.ParticipantsForty-three stakeholders were interviewed including clinicians (incorporating laboratory staff and members of trust POCT committees), commissioners, industry, regulators and patients.ResultsThematic analysis highlighted 32 barriers in six themes and 28 facilitators in eight themes to the adoption of POCTs. Six themes were common to both barriers and facilitators (clinical, cultural, evidence, design and quality assurance, financial and organisational) and two themes contained facilitators alone (patient factors and other (non-financial) resource use).ConclusionsFindings from this study demonstrate the complex motivations of stakeholders in the adoption of POCT. Most themes were common to both barriers and facilitators suggesting that good device design, stakeholder engagement and appropriate evidence provision can increase the likelihood of a POCT device adoption. However, it is important to realise that while the majority of identified barriers may be perceived or mitigated some may be absolute and if identified early in device development further investment should be carefully considered.

BMJ Open ◽  
2014 ◽  
Vol 4 (8) ◽  
pp. e005611-e005611 ◽  
Author(s):  
J. Howick ◽  
J. W. L. Cals ◽  
C. Jones ◽  
C. P. Price ◽  
A. Pluddemann ◽  
...  

2016 ◽  
Vol 17 (1) ◽  
Author(s):  
Victoria Hardy ◽  
Matthew Thompson ◽  
William Alto ◽  
Gina A. Keppel ◽  
Jaime Hornecker ◽  
...  

Author(s):  
Alison Bray ◽  
Emmanouela Kampouraki ◽  
Amanda Winter ◽  
Aaron Jesuthasan ◽  
Ben Messer ◽  
...  

It is recommended that developers of Point Of Care Tests (POCTs) assess the care pathway of the patient population of interest in order to understand if the POCT fits within the pathway and has the potential to improve it. If the variation of the pathway across potential hospitals is large, then it is likely that the evaluation of effectiveness is harder and the route towards large-scale takes adoption longer. Evaluating care pathways can be a time-consuming activity when conducted through clinical audits or interviews with healthcare professionals. We have developed a more rapid methodology which extrapolates the care pathway from local hospital guidelines and assesses their variation. Sepsis kills 46,000 people per year in the UK with societal costs of up to £10 billion. Therefore, there is a clinical need for an optimized pathway. By applying our method in this field, we were able to assess the variation in current hospital guidelines for sepsis and infer the potential impact this may have on the evidence development on innovations in this applications. We obtained 15 local sepsis guidelines. Two independent reviewers extracted: use of the national early warning score (NEWS), signs and risk factors informing the decision to prescribe antibiotics, and the number of decisional steps up to this point. Considerable variation was observed in all the variables, which is likely to have an impact on future clinical and economic evaluations and adoption of POCT for the identification of patients with sepsis.


2015 ◽  
Vol 4 (1) ◽  
pp. 68-77 ◽  
Author(s):  
Susan C. Peirce ◽  
Alex Faulkner ◽  
Selda Ulucanlar ◽  
Glyn Elwyn

2019 ◽  
Author(s):  
Hannah McCulloch ◽  
Agata Pacho ◽  
Rebecca Geary ◽  
Syed Tariq Sadiq ◽  
Sebastian Fuller

BackgroundYoung people in the UK are at high risk for sexually transmitted infections (STIs), despite STI testing being freely and confidentially available. Given multiple barriers they may face for attending sexual health clinics (SHCs), young people should be consulted regarding changes to care. Studies have shown that point-of-care tests (POCTs) for STIs, which can accurately diagnose and treat patients in one clinical visit, have potential for individual and public health benefits, yet patient opinions of changes to clinical practice associated with POCT implementation are less understood.MethodsThe Precise study explored patient experiences of UK SHC services and their opinions of POCT implementation plans; here we focus on young participants within the Precise study. Male and female attendees of three SHCs in England were purposively sampled and then invited to participate in a qualitative in-depth interview. Interviews were conducted one-on-one, in person or via telephone, were audio-recorded and transcribed. NVivo (V10) was used to organise data for our content-based analysis.ResultsTen young people aged 17-22 years, including: three women-who-have-sex-with-men, four men-who-have-sex-with-women and three men-who-have-sex-with-men were interviewed between June 2015 and February 2016. Participants reported SHCs as the best place to receive results because treatment could be stared immediately, with advice and information available. Participants discussed the potential for POCTs to reduce anxiety currently felt waiting for laboratory results. POCTs were found broadly acceptable, and were generally regarded as an innovation to improve SHC experiences. Participants with less previous SHC experience raised concerns that implementation of POCTs could negatively affect the amount and quality of time patients spend in consultations with clinicians and that changes to pathways may cause confusion in clinic.ConclusionsWe advise POCT implementation be accompanied by SHC staff communicating changes in clinical pathways to patients, including method and timeline for receiving results. Our participants valued face-to-face counselling and advice currently experienced in SHCs; these findings emphasise that POCT implementation plans safe-guard these aspects of care. Our findings suggest that POCT implementation in SHCs has potential to improve young people’s clinical experiences, which may facilitate attendance.


Author(s):  
Daniel Berman

How can we prevent the rise of resistance to antibiotics? In this video, Daniel Berman,  Nesta Challenges, discusses the global threat of AMR and how prizes like the Longitude Prize can foster the development of rapid diagnostic tests for bacterial infections, helping to contribute towards reducing the global threat of drug resistant bacteria. Daniel outlines how accelerating the development of rapid point-of-care tests will ensure that bacterial infections are treated with the most appropriate antibiotic, at the right time and in the right healthcare setting.


Viruses ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 18
Author(s):  
Michèle Bergmann ◽  
Mike Holzheu ◽  
Yury Zablotski ◽  
Stephanie Speck ◽  
Uwe Truyen ◽  
...  

Measuring antibodies to evaluate dogs´ immunity against canine parvovirus (CPV) is useful to avoid unnecessary re-vaccinations. The study aimed to evaluate the quality and practicability of four point-of-care (POC) tests for detection of anti-CPV antibodies. The sera of 198 client-owned and 43 specific pathogen-free (SPF) dogs were included; virus neutralization was the reference method. Specificity, sensitivity, positive and negative predictive value (PPV and NPV), and overall accuracy (OA) were calculated. Specificity was considered to be the most important indicator for POC test performance. Differences between specificity and sensitivity of POC tests in the sera of all dogs were determined by McNemar, agreement by Cohen´s kappa. Prevalence of anti-CPV antibodies in all dogs was 80% (192/241); in the subgroup of client-owned dogs, it was 97% (192/198); and in the subgroup of SPF dogs, it was 0% (0/43). FASTest® and CanTiCheck® were easiest to perform. Specificity was highest in the CanTiCheck® (overall dogs, 98%; client-owned dogs, 83%; SPF dogs, 100%) and the TiterCHEK® (overall dogs, 96%; client-owned dogs, 67%; SPF dogs, 100%); no significant differences in specificity were observed between the ImmunoComb®, the TiterCHEK®, and the CanTiCheck®. Sensitivity was highest in the FASTest® (overall dogs, 95%; client-owned dogs, 95%) and the CanTiCheck® (overall dogs, 80%; client-owned dogs, 80%); sensitivity of the FASTest® was significantly higher compared to the one of the other three tests (McNemars p-value in each comparison: <0.001). CanTiCheck® would be the POC test of choice when considering specificity and practicability. However, differences in the number of false positive results between CanTiCheck®, TiterCHEK®, and ImmunoComb® were minimal.


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