Ankle to brachial systolic pressure index at rest increases with age in asymptomatic physically active participants

Background: The prevalence of exercise-induced ischemia in the asymptomatic limb of patients with unilateral claudication based on history and treadmill evaluation, and with unilateral ipsilateral peripheral artery disease (i.e ankle-to-brachial systolic pressure index <0.90) is unknown. Methods: We detected exercise-induced ischemia in the asymptomatic limb of patients with apparently unilateral claudication. Among 6059 exercise-oximetry tests performed in 3407 nondiabetic and 961 diabetic patients. We estimated the intensity of ischemia in the both limb (buttocks and calves) using the lowest minimum value of the decrease from rest of oxygen pressure (DROP; limb changes minus chest changes from rest), with significant ischemia defined as DROP lower than −15 mmHg. Results: We found 152 tests performed in 142 nondiabetic patients and 40 tests performed in 38 diabetic patients. The asymptomatic limb showed significant ischemia in 46.7% and 37.5% of the tests. Strictly unilateral exercise-induced claudication with apparently unilateral peripheral artery disease was rare (<4% of all tests). However, among these highly selected tests, significant ischemia was found in the asymptomatic limb in more than one-third of cases. Conclusion: The asymptomatic limb of patients with peripheral artery disease should not be considered a normal limb.

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The diagnostic value of the measurement of the ankle-brachial systolic pressure index in primary health care

Journal of Clinical Epidemiology ◽

10.1016/s0895-4356(96)00275-2 ◽

1996 ◽

Vol 49 (12) ◽

pp. 1401-1405 ◽

Cited By ~ 84

Author(s):

Henri E.J.H. Stoffers ◽

Arnold D.M. Kester ◽

Victor Kaiser ◽

Paula E.L.M. Rinkens ◽

Peter J.E.H.M. Kitslaar ◽

...

Keyword(s):

Health Care ◽

Primary Health Care ◽

Systolic Pressure ◽

Diagnostic Value ◽

Pressure Index ◽

Primary Health ◽

Brachial Systolic Pressure

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Relationships of Age and Gender with Ankle-brachial Systolic Pressure Index and Cardio-ankle Vascular Index in Patients with Diabetes Mellitus

International Journal of Gerontology ◽

10.1016/j.ijge.2017.05.004 ◽

2018 ◽

Vol 12 (1) ◽

pp. 32-36 ◽

Cited By ~ 1

Author(s):

Mikio Marumo ◽

Shigeyuki Ebara ◽

Ikumi Nishibe ◽

Jun-ichi Soneda ◽

Ichiro Wakabayashi

Keyword(s):

Diabetes Mellitus ◽

Systolic Pressure ◽

Age And Gender ◽

Pressure Index ◽

Patients With Diabetes ◽

And Gender ◽

Brachial Systolic Pressure

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Interpretation and significance of ankle-brachial systolic pressure index

Seminars in Vascular Surgery ◽

10.1053/j.semvascsurg.2014.01.002 ◽

2013 ◽

Vol 26 (2-3) ◽

pp. 86-94 ◽

Cited By ~ 19

Author(s):

Sae Hee Ko ◽

Dennis F. Bandyk

Keyword(s):

Systolic Pressure ◽

Pressure Index ◽

Brachial Systolic Pressure

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Assessment of low ABSPI among arsenic exposed and non-exposed populations: A pilot study

Bangladesh Medical Research Council Bulletin ◽

10.3329/bmrcb.v36i1.5426 ◽

2010 ◽

Vol 36 (1) ◽

pp. 23-26 ◽

Cited By ~ 3

Author(s):

Manzurul Haque Khan ◽

Sudipta Sarkar ◽

Nasreen Khan ◽

A.F.M. Sarwar ◽

Sk. Akhtar Ahmad

Keyword(s):

Blood Pressure ◽

Systolic Pressure ◽

Arterial Disease ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Pressure Index ◽

Diabetic Status ◽

Peripheral Arterial ◽

Brachial Systolic Pressure

This cross-sectional study was carried out to assess and compare Ankle Brachial Systolic Pressure Index (ABSPI) amongst 120 arsenic exposed and 120 non-exposed populations of Samta village in Bangladesh. Abnormal ABSPI was more prevalent in arsenic exposed (13.3%) than in non-exposed (2.5%) group. The prevalence of abnormal ABSPI for respondents when adjusted for age, sex, BMI, blood pressure status and diabetic status, the prevalence remain significantly different. The findings suggest that those exposed to arsenic have increased chance of having abnormal ABSP and hence increased chance of peripheral arterial disease in Bangladesh. Online: 18 July 2010DOI: http://dx.doi.org/10.3329/bmrcb.v36i1.5426Bangladesh Med Res Counc Bull 2010; 36: 23-26

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Relationship between symptomatic lower limb peripheral artery disease and calcified carotid artery plaque detected on panoramic images of neurologically asymptomatic males

Dentomaxillofacial Radiology ◽

10.1259/dmfr.20180432 ◽

2019 ◽

Vol 48 (5) ◽

pp. 20180432

Author(s):

Hoang-Anh Tran ◽

Jessica B O'Connell ◽

Urie K Lee ◽

John C Polanco ◽

Tina I Chang ◽

...

Keyword(s):

Risk Factors ◽

Carotid Artery ◽

Systolic Pressure ◽

Outcome Variable ◽

Risk Indicator ◽

Pressure Index ◽

Significant Difference ◽

Panoramic Images ◽

Male Patients ◽

Brachial Systolic Pressure

Objective: Males with peripheral arterial disease (PAD) are at high risk of ischaemic stroke given that atherogenic risk factors for both diseases are similar. We hypothesized that neurologically asymptomatic males diagnosed with PAD would demonstrate calcified carotid artery plaques (CCAP) on panoramic images (PI) significantly more often than similarly aged males not having PAD. Methods: Investigators implemented a retrospective cross-sectional study. Subjects were male patients over age 50 diagnosed with PAD by ankle-brachial systolic pressure index results of [Formula: see text]0.9. Controls negative for PAD had an ankle-brachial systolic pressure index > 0.9. Predictor variable was a diagnosis of PAD and outcome variable was presence of CCAP. Prevalence of CCAP amongst the PAD+ patients was compared to prevalence of CCAP among PAD- patients. Descriptive and bivariate statistics were computed and p-value was set at 0.05. Results: Final sample size consisted of 234 males (mean age 72.68 ± 9.09); 116 subjects and 118 controls. Among the PAD+ cohort, CCAP+ prevalence rate (57.76%) was significantly (p = 0.001) greater than the CCAP+ rate (36.44%) of the PAD- (control). There was no significant difference in atherogenic “risk factors” in the PAD+ cohort between CCAP+ and CCAP– subjects. Conclusion: We demonstrated that CCAP, a “risk factor” for future stroke and “risk indicator” of future myocardial infarction is seen significantly more often detected on the PIs of older male patients with PAD than among those without. Dentists treating patients with PAD must be uniquely vigilant for the presence of CCAPs on their patients’ PI.

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Ankle Systolic Pressure Index and Early Vein Graft Failure-Reply

Archives of Surgery ◽

10.1001/archsurg.1979.01370330113024 ◽

1979 ◽

Vol 114 (9) ◽

pp. 1091

Author(s):

FRANK W. LOGERFO

Keyword(s):

Vein Graft ◽

Graft Failure ◽

Systolic Pressure ◽

Pressure Index ◽

Vein Graft Failure

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Abstract 12880: A Clinical Index of Myocardial Afterload Can Replace Wall Stress Calculations

Circulation ◽

10.1161/circ.142.suppl_3.12880 ◽

2020 ◽

Vol 142 (Suppl_3) ◽

Author(s):

Nathaniel Reichek ◽

Jonathan Weber ◽

Madhavi Kadiyala ◽

Marie Grgas ◽

Tazim Merchant ◽

...

Keyword(s):

Treatment Guidelines ◽

Systolic Pressure ◽

Wall Stress ◽

Stress Index ◽

Stress Indices ◽

Lv Volume ◽

And Gender ◽

Brachial Systolic Pressure ◽

Myocardial Level

Introduction: Afterload at the myocardial level is a principal determinant of LV chamber and myocardial wall function, generated by interplay of LV pressure, volume, and mass. Quantitation has relied on wall stress indices which require additional measurements and calculations as well as incorrect assumptions. Unfamiliar to most clinicians, they have largely fallen out of use, but the role of myocardial afterload in contemporary heart failure pathophysiology and therapy merits reevaluation given the roles of EF and myocardial strains in prognostic indices and treatment guidelines. Hypothesis: A simple clinical afterload index using variables fundamental to wall stress indices (systolic pressure(mmHg) * LV volume(ml))/LV mass(g)) or PV/M correlates closely with stress indices and relates similarly to LV EF and myocardial strains. Methods: In 277 normals (54% female, mean age 50.9±12.9 yrs) and small cohorts with dilated non-ischemic cardiomyopathy(35), aortic stenosis(12) and cancer chemotherapy(43), each with matched controls, we used CMR LV volumes, mass and brachial systolic pressure during imaging to compare end-systolic PV/M to stress indices and systolic pressure alone using correlations and correlation standard errors(SEs). Results: There were extremely close correlations (r= 0.97-0.99, all p< 0.001) with minimal SEs between PV/M and Arts and Alters stress indices with similar slopes in all groups and in normal subgroups by age and gender. Negative correlations with EF, global strains and strain rates were also present and extremely similar in all groups. But Mirsky’s stress index and brachial pressure performed less well. Conclusions: A simple clinical afterload index correlates closely with wall stress indices and similarly with LV ejection fraction and strains. It can support efficient reassessment of the role of afterload at the myocardial level in research and potentially, in clinical practice.

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The ratio between ankle and brachial systolic pressure in patients with sustained uncomplicated essential hypertension

Clinical Science ◽

10.1042/cs0740179 ◽

1988 ◽

Vol 74 (2) ◽

pp. 179-182 ◽

Cited By ~ 6

Author(s):

Ch. J. Hugue ◽

M. E. Safar ◽

M. Ch. Aliefierakis ◽

R. G. Asmar ◽

G. M. London

Keyword(s):

Essential Hypertension ◽

Doppler Ultrasound ◽

Systolic Pressure ◽

Normal Subjects ◽

Lower Limbs ◽

Arterial Stenosis ◽

Brachial Systolic Pressure ◽

Male Subjects ◽

Two Populations ◽

Normal Controls

1. The ratio between ankle (ASP) and brachial (BSP) systolic pressures was studied using Doppler ultrasound in 66 male subjects, 33 with sustained uncomplicated essential hypertension and 33 age-matched normal controls. 2. Based on covariance analysis, the ASP–BSP relationship was significantly different in the two populations, the ASP/BSP ratio (mean ± sem) being significantly lower in hypertensive subjects (106 ± 1 vs 132 ± 2; P < 0.001). 3. While the ASP/BSP ratio was negatively correlated with age in normal subjects, no significant correlation was observed in hypertensive subjects. 4. The diameter of the terminal abdominal aorta measured by echography was significantly greater in hypertensive subjects, while full examination with Doppler ultrasound excluded any significant arterial stenosis of the lower limbs. 5. The study suggested that, in patients with sustained uncomplicated essential hypertension, the lower ASP/BSP ratio is related to changes in arterial wave transmission.

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