Large granular lymphocyte leukaemia study at the University Hospital of Donostia

2021 ◽  
pp. jclinpath-2020-207191
Author(s):  
Alasne Uranga ◽  
Carmen González ◽  
J R Furundarena ◽  
Naiara Robado ◽  
Mercedes Rey ◽  
...  
Keyword(s):  
Nk Cell ◽  
Large Granular Lymphocyte ◽  
University Hospital ◽  
Lower Percentage ◽  
Female Ratio ◽  
Clonal Proliferation ◽  
Large Granular Lymphocyte Leukaemia ◽  
The One ◽  
The University ◽  
Male To Female

IntroductionLarge granular lymphocyte (LGL) leukaemia is considered a mature T-cell or natural killer (NK) cell neoplasm, characterised by a clonal proliferation of LGL.AimsTo analyse the characteristics and to establish (if possible) the prognostic parameters of these patients diagnosed in a single centre: University Hospital of Donostia.MethodsWe retrospectively studied data about 308 patients with LGL leukaemia diagnosed in our centre.ResultsThe frequency of T-LGL leukaemia and chronic lymphoproliferative disorder of NK cells was 89% and 6.8% respectively, and no aggressive NK-LGL leukaemia was seen in our population. The median age at diagnosis was 65.7 years and male-to-female ratio was 1.08. 59% of our patients were asymptomatic at the time of diagnosis. Most patients presented lymphocytosis and 63.6% more than 20% LGLs in the peripheral blood count, but it has to be taken into account that these results may be influenced by the selection bias of our study, as we recognised these patients as ‘alarms of the laboratory analysers’. Neutropenia was the most common cytopenia, and autoimmune disorders were described in 16.5% of the patients. Only 12 patients (3.9%) required treatment, a much lower percentage that the one reported in the literature, and this is consistent with the fact that patients were less symptomatic than in other series, as we expected. The 5-year and 15-year overall survival was 92% and 87%, respectively.ConclusionsOur patients may represent the even more benign end of the spectrum of clonal T LGL and NK proliferations.

scholarly journals Human Resources Management in the Public Hospital Case of the University Hospital Centre of Oran

2017 ◽  
Vol 8 (1) ◽  
pp. 100
Author(s):  
Ghrissi Larbi
Keyword(s):  
Human Resources ◽  
Public Hospital ◽  
Human Resources Management ◽  
University Hospital ◽  
Resources Management ◽  
The Public ◽  
Hospital Case ◽  
The One ◽  
The University

:it would seem that the University Hospital Centre of Oran suffers from an insufficiency in the control ¶existing human resources and of an inadequacy enters the needs and the profiles ¶existing on the one hand, and that it would not have a true policy of management of ¶human resources which would enable him to benefit best from the resources ¶human available to take up the challenges of management and the development of ¶services provided to the patients.¶

scholarly journals Effects of the COVID-19 Pandemic on the Epidemiology of Knee and Shoulder Arthroscopy

2021 ◽  
Vol 58 ◽  
pp. 004695802110560
Author(s):  
Krystian Kazubski ◽  
Łukasz Tomczyk ◽  
Piotr Morasiewicz
Keyword(s):  
Hospital Stay ◽  
Shoulder Arthroscopy ◽  
Demographic Data ◽  
Epidemiological Data ◽  
University Hospital ◽  
Female Ratio ◽  
Duration Of Hospital Stay ◽  
The Mean ◽  
Orthopedic Patients ◽  
Male To Female

The purpose of our study was to comprehensively assess the effect of the COVID-19 pandemic on knee and shoulder arthroscopy performed in an orthopedic department of a university hospital in Poland. This study compared the data on all shoulder and knee arthroscopy procedures performed in two different periods: The period of the COVID-19 pandemic in Poland (from March 4, 2020, to October 15, 2020) and the corresponding period prior to the pandemic (March 4, 2019, to October 15, 2019). The study evaluated epidemiological data, demographic data, and hospital stay duration. The total number of arthroscopy procedures conducted in the evaluated period in 2020 was approximately 8.6% higher than that in the corresponding 2019 period. The mean duration of hospital stay for orthopedic patients after their knee or shoulder arthroscopy was 3.1 days in 2020 and 2.8 days in 2019. Our study revealed the mean age of arthroscopy patients during the pandemic to be lower at 48.4 years than the 51.2 years recorded in 2019. The male-to-female ratio was shown to be lower at .85 during the pandemic, having decreased from 1.5 in 2019. The COVID-19 pandemic did not reduce the number of arthroscopy performed at our center, and the mean age of the patients did not change. However, the pandemic had a marked effect on the mean duration of hospital stay and male-to-female ratio.

scholarly journals Aetiological factors of hoarseness in patients attending at Kathmandu University Hospital

2013 ◽  
Vol 19 (1) ◽  
pp. 14-17 ◽  
Author(s):  
Bikash Lal Shrestha ◽  
Ram Chaya Man Amatya ◽  
Sekhar KC ◽  
Inku Shrestha ◽  
Monika Pokharel
Keyword(s):  
Longitudinal Study ◽  
Age Groups ◽  
University Hospital ◽  
Microsoft Excel ◽  
Special Investigation ◽  
Female Ratio ◽  
Common Cause ◽  
Manual Analysis ◽  
History Of ◽  
Male To Female

Objective: To evaluate the aetiological factors of hoarseness. Methods: This is a prospective, non- randomized and longitudinal study conducted from 1st august 2011 to 1st august 2012 in department of otorhinolaryngology of Kathmandu university Hospital, Dhulikhel, Nepal. All the patients with history of hoarseness underwent clinical examination, routine as well as special investigation to find the diagnosis. The final results were analyzed by simple manual analysis with frequency and percentage using Microsoft Excel software 2007. Results: There were total 280 patients included in the study. Among them the age groups of 21 – 30 years and 31 – 40 years were mainly suffer from hoarseness. Similarly, among 280 patients 200 (71.45%) were males whereas 80 (28.6%) were females with male to female ratio of 2.5:1.. The most common cause as per the distribution was acid peptic laryngitis with frequency of 37.8% whereas tuberculosis of larynx, papillary carcinoma of thyroid and papilloma of vocal cord accounts for only 0.4% each. Conclusion: There was etiological variation in hoarseness ranging from simple laryngitis to malignancies. So it is important not to ignore the hoarseness and precise history, examination and investigations should be done. DOI: http://dx.doi.org/10.3329/bjo.v19i1.11877 Bangladesh J Otorhinolaryngol 2013; 19(1): 14-17

Stroke in a Subsaharan Nigerian Hospital—A Retrospective Study

1989 ◽  
Vol 19 (1) ◽  
pp. 11-14 ◽  
Author(s):  
S A Bwala
Keyword(s):  
Duration Of Symptoms ◽  
Female Ratio ◽  
Transient Ischaemic Attacks ◽  
History Of ◽  
Hospital Deaths ◽  
Insulin Dependent ◽  
The Mean ◽  
The University ◽  
First Time ◽  
Male To Female

The case records of 53 consecutive Nigerian inpatients with stroke in the University of Maiduguri Teaching Hospital, Maiduguri were retrospectively reviewed. The mean age at presentation was 55 years and the male to female ratio was 2.5: 1. The mean duration of symptoms before presentation was 11.1 weeks and the average duration of stay in hospital was 3 weeks. Thirty-three (63%) of the lesions were infarctive and 19 (37%) were haemorrhagic. Only 3 (6%) patients gave a history of prior transient ischaemic attacks (TIAs). Forty-two (79%) patients were hypertensive at presentation out of which 27 (64%) had the hypertension diagnosed for the first time. Four (8%) patients were non-insulin dependent diabetics. There were 11 hospital deaths (21%). Thus hypertension, more than half undiagnosed at admission, was the most common risk factor for stroke in the hospital population studied.

scholarly journals Obstructive Neoplastic Anuria Overview at Ibn Rochd University Hospital–A Retrospective Study

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Moussaab Rachid ◽  
Youness Chakir ◽  
Mahdi Graiouid ◽  
Mahmoud Alafifi ◽  
Mohammed Dakir ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Locally Advanced ◽  
Percutaneous Nephrostomy ◽  
University Hospital ◽  
Female Ratio ◽  
Pelvic Tumors ◽  
Female Predominance ◽  
Obstructive Anuria ◽  
Male To Female

Introduction : Obstructive anuria due to pelvic cancers is the most common obstructive anuria in our context, its diagnosis is easy, but it causes a lot of morbidity with often heavy and long management.                                      Materials and methods : This is a retrospective study containing 40 cases of confirmed neoplastic anuria treated in the urology department at the Ibn Rochd University Hospital in Casablanca Morocco between January 2016 and October 2018. Purpose : The aim of our study was to establish the epidemiological, clinical, therapeutic and natural historyin patients with neoplastic obstructive anuria. Results : The mean age was 56 years old with a notable female predominance. The male to female ratio was 0.6. Sixty percent (60%) of our patients were consulted within24 hours after the onset of anuria, the main symptoms preceding or accompanying anuria were lower back pain (75%) and hematuria (37.5%). Criteria for a positive diagnosis included urinary retention with complete absence of diuresis, the anuria was confirmed by probing or ultrasound, dilation of the urinary excretory system on ultrasound and acute impairment of renal function. To prevent patient from going into metabolic disorders, hemodialysis was performed in 27 patients (67.5%). Internal diversion of urine by mounting a JJ catheter was initially attempted in 40% of the cases. In case of attempt failure, or in case of locally advanced pelvic tumors, percutaneous nephrostomy was performed with a success rate of 100%. Upon follow up for 30 months, mortality rate was 5% (n=2), 95% of the patients benefited from a specialized follow-up for their etiological neoplasm.  Conclusion : The management of neoplastic obstructive anuria must be rapid, the type of urinary diversion is chosen according to the clinical presentation and the technical platform available.

scholarly journals Effects of the COVID-19 Pandemic on the Epidemiology of Knee and Shoulder Arthroscopy Procedures in a University Hospital Department in Poland

2021 ◽  
Author(s):  
Krystian Kazubski ◽  
Łukasz Tomczyk ◽  
Piotr Morasiewicz
Keyword(s):  
Hospital Stay ◽  
Shoulder Arthroscopy ◽  
Demographic Data ◽  
Epidemiological Data ◽  
University Hospital ◽  
Female Ratio ◽  
Duration Of Hospital Stay ◽  
The Mean ◽  
Orthopedic Patients ◽  
Male To Female

Abstract Background: The purpose of our study was to comprehensively assess the effect of the COVID-19 pandemic on knee and shoulder arthroscopies performed in an orthopedic department of a university hospital in Poland.Methods: This study compared the data on shoulder and knee arthroscopy procedures performed in two different periods: the period of the COVID-19 pandemic in Poland (from March 4, 2020 to October 15, 2020) and the corresponding period prior to the pandemic (March 4, 2019–October 15, 2019). The study evaluated epidemiological data, demographic data, and hospital stay duration.Results: The total number of arthroscopy procedures conducted in the evaluated period in 2020was approximately 8.6% higher than that in the corresponding 2019 period.The mean duration of hospital stay for orthopedic patients after their knee or shoulder arthroscopy was 3.1 days in 2020 and 2.8 days in 2019. Our study revealed the mean age of arthroscopy patients during the pandemic to be lower at 48.4 years than the 51.2 years recorded in 2019.The male-to-female ratio was shown to be lower at 0.85 during the pandemic, having decreased from 1.5 in 2019Conclusions: The COVID-19 pandemic did not reduce the number of arthroscopies performed at our center and the mean age of the patients did not change. However, the pandemic had a marked effect on the mean duration of hospital stay and male-to-female ratio.

scholarly journals DENTAL AESTHETIC;

2017 ◽  
Vol 24 (02) ◽  
pp. 347-351
Author(s):  
Irum Naz Jutt ◽  
Aamir Mehmood Bhut ◽  
Atiq Ur Rehman ◽  
Waqar Memon
Keyword(s):  
Orthodontic Treatment ◽  
Psychosocial Impact ◽  
University Hospital ◽  
Female Ratio ◽  
Self Confidence ◽  
The Social ◽  
Dental Aesthetics ◽  
Minimum Age ◽  
Grade Ii ◽  
Male To Female

Objectives: Psychosocial impact of dental aesthetic in patients visiting OPD ofLiaquat University Hospital Jamshoro. Study Design: Observational study. Place and Durationof Study: This study was conducted at Dental Section, Liaquat University Hospital Jamshoro,from July 2013 to December 2014. Methodology: This study consisted of one hundred andeight cases were selected during this period from orthodontic clinic OPD. Principle investigatorreviewed the patients using structured questionnaire. Psychosocial Impact of Dental AestheticsQuestionnaire’ (PIDAQ) were analyzed to assess the dental aesthetics by using the DentalAesthetic Index (DAI).” Inclusion criteria were patient’s aged 25 years and having no previoushistory of orthodontic treatment. Those patients already on treatment, presence of craniofacialsyndromes or anomalies and “Patients with any mental or behavioral disorders that might havereduced their ability for self-determination were excluded. Malocclusion orthodontic treatmentrecommendations to the priorities assigned to four classes per grade. The first factor is theDental Self-Confidence that consists of 6 items from the Self-Confidence Scale. Results: Atotal of 108 patients, both males and females were included in the study. 69(63.88%) out of108 subjects were males and rest were females 39(36.11%) cases, male to female ratio 1:1.7.The minimum age was 25 years and maximum was 55years but most of the patients werein the range of 25 to 35 years means age was 27+4.7 years. In this study DAI scores wereobserved, grade-I in 53(49.07%), grade-II in 32(29.62 %), grade-III in 14(12.96 %) and grade-IVin 9(8.33 %). Conclusion: Patients who seek orthodontic treatment are anxious to improve theirappearance and approval of the social, more often associated with improved oral work or life.”

scholarly journals Efficacy Of Gabapentin In Trigeminal Neuralgia: A Non-randomized Trial

2018 ◽  
Vol 08 (03) ◽  
pp. 151-154
Author(s):  
Nasir Ali Khan ◽  
Samia Siraj ◽  
Usman Mahmood ◽  
Fauzia Sidiqui ◽  
Daud Mirza ◽  
...  
Keyword(s):  
Trigeminal Neuralgia ◽  
Rating Scale ◽  
University Hospital ◽  
Pain Rating ◽  
Female Ratio ◽  
Significant Difference ◽  
Numeric Pain Rating Scale ◽  
Convenience Sampling ◽  
Male To Female ◽  
Pain Rating Scale

Objective: To compare the efficacy of Gabapentin with carbamazepine in Trigeminal Neuralgia. Material/Method: The study was conducted in Agha Khan University Hospital and Abbasi Shaheed Hospital for four months. 19 patients of TN were collected through purposive convenience sampling. DN4 questionnaire was used to differentiate between Somatic and Neuropathic pain. Numeric Pain Rating Scale was used to assess the severity of pain. Results: Nine patients of Trigeminal Neuralgia refractory to carbamazepine were put on Gabapentin with male to female ratio of 4:5. All showed favorable response on 800-1600 mg Gabapentin on Numeric Pain Rating Scale. All patients were pain free in three weeks with no side effects. There was significant difference between pain response to carbamazepine and Gabapentin at P< .05. Four patients (44%) had pain relief on 900 mg Gabapentin, three (33%) on 1200 mg, one responded on 800 mg and one on 1600 mg. Conclusion: Gabapentin is effective as first line treatment in Trigeminal Neuralgia

Vernal Keratoconjunctivitis in Nigerians: 109 Consecutive Cases

2003 ◽  
Vol 33 (4) ◽  
pp. 242-245 ◽  
Author(s):  
Catherine U Ukponmwan
Keyword(s):  
Vernal Keratoconjunctivitis ◽  
Common Symptom ◽  
Atopic Diseases ◽  
Self Medication ◽  
Female Ratio ◽  
Benin City ◽  
History Of ◽  
The University ◽  
Age Range ◽  
Male To Female

Vernal keratoconjunctivitis was the most common conjunctival disease seen over a 2 year period (January 1997–December 1998) at the University of Benin Teaching Hospital, Benin City, Nigeria. One hundred and nine consecutive patients were seen with vernal keratoconjunctivitis. There was a male to female ratio of 1:1.3. The age range of the patients was 5 months to 38 years with a mean age of 15.5 ± 8.3 years (SD). Of the patients 54.1% were children. Itching was the most common symptom, followed by redness, tearing, aching eye and photophobia. Ninety patients (82.6%) had predominantly tarsal papillae, while the others had mixed and limbal papillae. A history of atopic diseases such as asthma and rhinitis was present in only five patients (4.5%). There was no patient with corneal ulcer or scarring. Although the complications were few, health education of the patients about the dangers of self medication with steroids should be emphasized.

scholarly journals The impact of COVID-19 epidemiological restriction guidelines measures in a Croatian tertiary colorectal cancer center

2020 ◽  
Vol 48 (2-3) ◽  
pp. 43-46
Author(s):  
Iva Kirac ◽  
◽  
Zvonimir Misir ◽  
Vesna Vorih ◽  
Loris Ćurt ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Colorectal Surgery ◽  
University Hospital ◽  
Cancer Center ◽  
Solid Cancer ◽  
Everyday Activities ◽  
The One ◽  
The University ◽  
The Impact ◽  
The Given

Background: In the past six months, Croatia faced a short lockdown and a slow return to most hospitals’ everyday activities. During the lockdown, our center, as a part of the University Hospital Centre specialized for solid cancer, was enabled to maintain most of the routine practices with the one-month colonoscopy exception. Aim: To determine the oscillation in the number of endoscopies and colorectal surgery for 13 months (six months pre and post COVID-19 lockdown). Materials and methods: From August 1st, 2019, until August 31st 2020, the hospital analytics determine the number of colonoscopies, screening colonoscopies, and surgeries. Results: During the given period number of detected and operated colorectal cancers was stable, except for April, when we mostly did not perform colonoscopies. Conclusion: We maintained a pre-COVID-19 pace in colorectal cancer treatment, colonoscopies, and colorectal surgery after epidemiological guidelines for colonoscopies and colorectal surgery were applied, owing to the relatively stable overall epidemiological situation.

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