scholarly journals Systolic blood pressure response after high-intensity interval exercise is independently related to decreased small arterial elasticity in normotensive African American women

2016 ◽  
Vol 41 (5) ◽  
pp. 484-490 ◽  
Author(s):  
Stephen J. Carter ◽  
TaShauna U. Goldsby ◽  
Gordon Fisher ◽  
Eric P. Plaisance ◽  
Barbara A. Gower ◽  
...  

Aerobic exercise transiently lowers blood pressure. However, limited research has concurrently evaluated blood pressure and small arterial elasticity (SAE), an index of endothelial function, among African American (AA) and European American (EA) women the morning after (i.e., ≈22 h later) acute bouts of moderate-intensity continuous (MIC) and high-intensity interval (HII) exercise matched for total work. Because of greater gradients of shear stress, it was hypothesized that HII exercise would elicit a greater reduction in systolic blood pressure (SBP) compared to MIC exercise. After baseline, 22 AA and EA women initiated aerobic exercise training 3 times/week. Beginning at week 8, three follow-up assessments were conducted over the next 8 weeks at random to measure resting blood pressure and SAE. In total all participants completed 16 weeks of training. Follow-up evaluations were made: (i) in the trained state (TS; 8–16 weeks of aerobic training); (ii) ≈22 h after an acute bout of MIC exercise; and (iii) ≈22 h after an acute bout of HII exercise. Among AAs, the acute bout of HII exercise incited a significant increase in SBP (mm Hg) (TS, 121 ± 14 versus HII, 128 ± 14; p = 0.01) whereas responses (TS, 116 ± 12 versus HII, 113 ± 9; p = 0.34) did not differ in EAs. After adjusting for race, changes in SAE were associated (partial r = −0.533; p = 0.01) with changes in SBP following HII exercise. These data demonstrate an acute, unaccustomed bout of HII exercise produces physiological perturbations resulting in a significant increase in SBP that are independently associated with decreased SAE among AA women, but not EA women.

Trials ◽  
2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Shen Menglu ◽  
Yang Suyong ◽  
Wang Xiaoyan ◽  
Wolfgang I. Schöllhorn ◽  
Zhu Dong

Abstract Introduction Cognitive deficit is a common syndrome of methamphetamine (MA) dependence. It is related to decision-making, control ability, and social functioning. High-intensity interval training (HIIT) is a training technique that requires people to work out at full intensity during a short period. Many studies have already shown the potential effects of HIIT on cognitive functions. The purpose of this trial is to evaluate the cognitive effects of HIIT on individuals with MA dependence. Methods and analysis A total of 240 individuals with MA dependence will be randomly assigned to the HIIT group, moderate-intensity continuous training (MICT) group and control (CON) group. HIIT will consist of a 24-min HIIT exercise on a treadmill. MICT will consist of a 1-h body–mind exercise. CON will be their traditional intervention. The experimental period will be 12 months with 3 interventions weekly for the first 6 months and follow-up for the next 6 months. All subjects will be given cognitive tests at baseline, after intervention and at follow-up. Cognitive performances will be compared by a mixed-model analysis for repeated measures. Discussion HIIT training may reduce illicit drug cravings amongst individuals with MA dependence; hence, HIIT may have a good effect on the cognitive functions, such as memory and executive function, of individuals with MA dependence. Trial registration Chinese Clinical Trial Registry ChiCTR2000032492. Registered on April 30, 2020 (http://www.chictr.org.cn/edit.aspx?pid=52127&htm=4)


2021 ◽  
Vol 12 ◽  
Author(s):  
Yoshinao Kobayashi ◽  
Akiko Eguchi ◽  
Yasuyuki Tamai ◽  
Sanae Fukuda ◽  
Mina Tempaku ◽  
...  

Introduction/PurposeHigh-intensity interval training (HIIT) promotes various biological processes and metabolic effects in multiple organs, but the role of extracellular vesicles (EVs) released from a variety of cells is not fully understood during HIIT exercise (HIIT-Ex). We investigated the changes in circulating number and proteomic profile of EVs to assess the effect of HIIT-Ex.MethodsSeventeen young men (median age, 20 years) were enrolled in the study. Total duration of the HIIT-Ex was 4 min. Blood samples were collected from before HIIT-Ex (pre-HIIT-Ex), at the immediate conclusion of HIIT-Ex (T0), at 30 min (T30), and at 120 min after HIIT-Ex. The pulse rate and systolic blood pressure were measured. Circulating EVs were characterized, and EV proteins were detected via nano liquid chromatography tandem mass spectrometry.ResultsThe pulse rate and systolic blood pressure at T0 to pre-HIIT-Ex were significantly higher. Circulating EV number was significantly altered throughout the HIIT-Ex, and the source of circulating EVs included skeletal muscle, hepatocytes, and adipose tissue. Proteomic analysis identified a total of 558 proteins within isolated circulating EVs from pre-HIIT-Ex, T0, and T30. Twenty proteins in total were significantly changed at pre-HIIT-Ex, T0, and T30 and are involved in a variety of pathways, such as activation of coagulation cascades, cellular oxidant detoxification, and correction of acid–base imbalance. Catalase and peroxiredoxin II were increased at T0.ConclusionThe circulating EV composition can be immediately changed by particularly a short time of HIIT-Ex, indicating that EVs may intercommunicate across various organs rapidly in response to HIIT-Ex.


2021 ◽  
Vol 6 (1) ◽  
pp. 20-26
Author(s):  
Riza Adriyani ◽  
Dody Iskandar ◽  
Ahmad Hendra Dana

Regular exercise is recommended for adults experiencing hypertension with low and moderate cardiovascular risk. High intensity interval training (HIIT) is an efficient training method and has a better cardiometabolic protective effect. The purpose of this study was to determine sex differences in blood pressure and body composition after high intensity interval training. Twenty two adults with hypertension and central obesity (male n = 16, age 35.56 ± 4.56 years, waist circumference 98.85 ± 6.85 cm, systolic blood pressure 134.22 ± 2.86 mmHg, diastolic blood pressure 85.03 ± 6.58 mmHg) - (female n = 6, age 37.83 ± 5.46 years, waist circumference 95.09 ± 7.49 cm, systolic blood pressure 133.50 ± 6.47 mmHg, diastolic blood pressure 89.80 ± 5.94 mmHg) participated in a high intensity interval training (HIIT). The HIIT consisted of 3x4 minutes training at 77– 95% of maximum heart rate interspersed by 3 minutes of active rest at 64-76% of of maximum heart rate. The training was conducted three sessions per week for 10 weeks. Systolic blood pressure and diastolic blood pressure were significantly reduced in men. There was an improvement in body composition parameters, including a decrease in waist-to-hip ratio, visceral fat, and body fat mass in men (p 0.05). Waist circumference decreased in both men and women (p 0.05). It concludes that there are sex differences in cardiometabolic adaptation after HIIT.


VASA ◽  
2016 ◽  
Vol 45 (5) ◽  
pp. 373-377 ◽  
Author(s):  
Sascha Ketelhut ◽  
Florian Milatz ◽  
Walter Heise ◽  
Reinhard G. Ketelhut

Abstract. Background: Regular physical activity is known to reduce arterial pressure (BP). In a previous investigation, we could prove that even a single bout of moderate-intensity continuous exercise (MICE) causes a prolonged reduction in BP. Whether high-intensity interval training (HIIT) has a favourable influence on BP, and therefore may be followed subjects and methods by a prolonged BP reduction, should be examined on the basis of blood pressure response after exercise and during a subsequent stress test. Patients and methods: In 39 healthy men (aged 34 ± 8 years, BMI 24 ± 2), peripheral and central BP were measured noninvasively at rest and at the end of a 2-min cold pressor test (CPT) using a Mobil-O-Graph (24 PWA monitor, IEM). Following HIIT (6 x 1 min at 98% of the previously determined maximum wattage, 4-min rest between intervals) BP was measured again throughout 60 min of rest and thereafter during a CPT. The results were compared with those obtained before HIIT. Results: Similar to MICE, peripheral and central BPs were significantly (p < 0.05) lower 45 min after HIIT. When analysing peripheral BP during a CPT before and after exercise, significantly lower systolic (p < 0.001) and diastolic (p = 0.008) pressures were established after HIIT. This was true for systolic (p = 0.002) and diastolic (p = 0.006) central BP as well. Although there were no more significant differences between pressures at rest before and 60 min after exercise, the increase in peripheral systolic pressure due to CPT was significantly slower after HIIT (p = 0.019) when compared with BP during CPT before exercise. This was true for central systolic BP as well (p = 0.017). Conclusion: HIIT leads to a BP reduction, which can still be detected up to 45 min after completion of the training. Even 60 min after exercise, pressures during a CPT showed a reduced augmentation, indicating an attenuated hemodynamic response to stress testing after HIIT.


Sign in / Sign up

Export Citation Format

Share Document