Use of An Age-Dependent Mark–Recapture Model in Fisheries Research

1983 ◽  
Vol 40 (9) ◽  
pp. 1449-1455 ◽  
Author(s):  
K. H. Pollock ◽  
R. H. K. Mann
Keyword(s):  
Survival Rate ◽  
Northern Pike ◽  
Fish Populations ◽  
Size Estimation ◽  
Differential Survival ◽  
Mark Recapture ◽  
Wide Range ◽  
Age Dependent ◽  
Using Data ◽  
And Migration

An age-dependent generalization of the Jolly–Seber mark–recapture model for fish populations subject to birth, death, and migration is illustrated using data from a study on northern pike (Esox lucius) in Dorset, England. These data show strong evidence of differential survival with age. We estimate the average annual survival rate to be 50% for the pike aged 2 or more years and 34% for those of age 1 yr. We believe that this age-dependent mark–recapture model could be very useful for a wide range of fisheries research and management problems. Often in fisheries work the assumption that survival is independent of age has not been examined critically. We present guidelines helpful in designing mark–recapture studies. This includes a useful design which increases precision and also allows population size estimation to be robust to unequal catchability (heterogeneity or trap response) within an age-class.

Migration and the Internet

2017 ◽  
Vol 14 (3) ◽  
pp. 331-342 ◽  
Author(s):  
Thomas John Cooke ◽  
Ian Shuttleworth
Keyword(s):  
United States ◽  
Information And Communication Technologies ◽  
Unobserved Heterogeneity ◽  
Panel Study ◽  
The United States ◽  
Negative Effect ◽  
Information And Communication ◽  
Using Data ◽  
And Migration ◽  
Dynamics Models

It is widely presumed that information and communication technologies, or ICTs, enable migration in several ways; primarily by reducing the costs of migration. However, a reconsideration of the relationship between ICTs and migration suggests that ICTs may just as well hinder migration; primarily by reducing the costs of not moving.  Using data from the US Panel Study of Income Dynamics, models that control for sources of observed and unobserved heterogeneity indicate a strong negative effect of ICT use on inter-state migration within the United States. These results help to explain the long-term decline in internal migration within the United States.

scholarly journals Risk factors for severity on admission and the disease progression during hospitalisation in a large cohort of patients with COVID-19 in Japan

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e047007
Author(s):  
Mari Terada ◽  
Hiroshi Ohtsu ◽  
Sho Saito ◽  
Kayoko Hayakawa ◽  
Shinya Tsuzuki ◽  
...  
Keyword(s):  
Risk Factors ◽  
Mechanical Ventilation ◽  
Chronic Respiratory Disease ◽  
Major Effect ◽  
Secondary Outcome ◽  
Healthcare Facilities ◽  
Wide Range ◽  
Registration Number ◽  
Using Data ◽  
Obesity Hypertension

ObjectivesTo investigate the risk factors contributing to severity on admission. Additionally, risk factors of worst severity and fatality were studied. Moreover, factors were compared based on three points: early severity, worst severity and fatality.DesignAn observational cohort study using data entered in a Japan nationwide COVID-19 inpatient registry, COVIREGI-JP.SettingAs of 28 September 2020, 10480 cases from 802 facilities have been registered. Participating facilities cover a wide range of hospitals where patients with COVID-19 are admitted in Japan.ParticipantsParticipants who had a positive test result on any applicable SARS-CoV-2 diagnostic tests were admitted to participating healthcare facilities. A total of 3829 cases were identified from 16 January to 31 May 2020, of which 3376 cases were included in this study.Primary and secondary outcome measuresPrimary outcome was severe or nonsevere on admission, determined by the requirement of mechanical ventilation or oxygen therapy, SpO2 or respiratory rate. Secondary outcome was the worst severity during hospitalisation, judged by the requirement of oxygen and/orinvasive mechanical ventilation/extracorporeal membrane oxygenation.ResultsRisk factors for severity on admission were older age, men, cardiovascular disease, chronic respiratory disease, diabetes, obesity and hypertension. Cerebrovascular disease, liver disease, renal disease or dialysis, solid tumour and hyperlipidaemia did not influence severity on admission; however, it influenced worst severity. Fatality rates for obesity, hypertension and hyperlipidaemia were relatively lower.ConclusionsThis study segregated the comorbidities influencing severity and death. It is possible that risk factors for severity on admission, worst severity and fatality are not consistent and may be propelled by different factors. Specifically, while hypertension, hyperlipidaemia and obesity had major effect on worst severity, their impact was mild on fatality in the Japanese population. Some studies contradict our results; therefore, detailed analyses, considering in-hospital treatments, are needed for validation.Trial registration numberUMIN000039873. https://upload.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000045453

scholarly journals The PI3K/Akt Pathway: Emerging Roles in Skin Homeostasis and a Group of Non-Malignant Skin Disorders

Cells ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 1219
Author(s):  
Yan Teng ◽  
Yibin Fan ◽  
Jingwen Ma ◽  
Wei Lu ◽  
Na Liu ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Akt Pathway ◽  
Skin Disorders ◽  
Phosphatidylinositol 3 Kinase ◽  
Skin Development ◽  
Wide Range ◽  
Malignant Skin ◽  
Solid Foundation ◽  
And Migration ◽  
Poor Outcomes

The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway regulates cell proliferation, differentiation, and migration, along with angiogenesis and metabolism. Additionally, it could mediate skin development and homeostasis. There is much evidence to suggest that dysregulation of PI3K/Akt pathway is frequently associated with several human cutaneous malignancies like malignant melanoma (MM), basal cell carcinoma (BCC), and cutaneous squamous cell carcinoma (SCC), as well as their poor outcomes. Nevertheless, emerging roles of PI3K/Akt pathway cascade in a group of common non-malignant skin disorders including acne and psoriasis, among others, have been recognized. The enhanced understanding of dysfunction of PI3K/Akt pathway in patients with these non-malignant disorders has offered a solid foundation for the progress of updated therapeutic targets. This article reviews the latest advances in the roles of PI3K/Akt pathway and their targets in the skin homeostasis and progression of a wide range of non-malignant skin disorders and describes the current progress in preclinical and clinical researches on the involvement of PI3K/Akt pathway targeted therapies.

More than just a pressure relief valve: physiological roles of volume-regulated LRRC8 anion channels

2019 ◽  
Vol 400 (11) ◽  
pp. 1481-1496 ◽  
Author(s):  
Lingye Chen ◽  
Benjamin König ◽  
Tianbao Liu ◽  
Sumaira Pervaiz ◽  
Yasmin S. Razzaque ◽  
...  
Keyword(s):  
Volume Regulation ◽  
Regulatory Volume Decrease ◽  
Anion Channel ◽  
Therapy Resistance ◽  
Cell Swelling ◽  
Organic Osmolytes ◽  
Anion Channels ◽  
Relief Valve ◽  
Wide Range ◽  
And Migration

Abstract The volume-regulated anion channel (VRAC) is a key player in the volume regulation of vertebrate cells. This ubiquitously expressed channel opens upon osmotic cell swelling and potentially other cues and releases chloride and organic osmolytes, which contributes to regulatory volume decrease (RVD). A plethora of studies have proposed a wide range of physiological roles for VRAC beyond volume regulation including cell proliferation, differentiation and migration, apoptosis, intercellular communication by direct release of signaling molecules and by supporting the exocytosis of insulin. VRAC was additionally implicated in pathological states such as cancer therapy resistance and excitotoxicity under ischemic conditions. Following extensive investigations, 5 years ago leucine-rich repeat-containing family 8 (LRRC8) heteromers containing LRRC8A were identified as the pore-forming components of VRAC. Since then, molecular biological approaches have allowed further insight into the biophysical properties and structure of VRAC. Heterologous expression, siRNA-mediated downregulation and genome editing in cells, as well as the use of animal models have enabled the assessment of the proposed physiological roles, together with the identification of new functions including spermatogenesis and the uptake of antibiotics and platinum-based cancer drugs. This review discusses the recent molecular biological insights into the physiology of VRAC in relation to its previously proposed roles.

scholarly journals Age‐dependent patterns of spatial autocorrelation in fish populations

Ecology ◽  
2021 ◽  
Author(s):  
Jonatan F. Marquez ◽  
Bernt‐Erik Sæther ◽  
Sondre Aanes ◽  
Steinar Engen ◽  
Are Salthaug ◽  
...  
Keyword(s):  
Spatial Autocorrelation ◽  
Fish Populations ◽  
Age Dependent

The digital divide in individual e-commerce utilization in China

2012 ◽  
Vol 29 (1) ◽  
pp. 69-80 ◽  
Author(s):  
Shizhan Zhu ◽  
Juan Chen
Keyword(s):  
Digital Divide ◽  
The Internet ◽  
Digital Inequality ◽  
Urban Inequality ◽  
First Order ◽  
Gender Education ◽  
Residency Status ◽  
Logistic Regressions ◽  
Using Data ◽  
And Migration

Using data from a national survey with 1,288 respondents, this study investigates the socio-demographic determinants of the first-order digital divide (access to the Internet) and the second-order digital divide (e-commerce use) in China. The survey employed spatial probability sampling technology so it would encompass migrants as well as registered residents. Multiple logistic regressions were applied to model the associations between access to the Internet/e-commerce use and demographic characteristics, socio-economic attributes, and migration and residency status. The results demonstrate the significant effects of rural-urban inequality and socio-economic divisions in Internet access. Age, gender, education, and residency were identified as significant predictors for individual e-commerce use. The findings provide helpful information for enterprises wishing to broaden their business horizons. The research can also be used in designing effective policies to reduce China’s digital inequality.

scholarly journals HMBG1 as a Driver of Inflammatory and Immune Processes in the Pathogenesis of Ocular Diseases

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Yi Liu ◽  
Guo-Bin Zhuang ◽  
Xue-Zhi Zhou
Keyword(s):  
Current Knowledge ◽  
High Mobility ◽  
Retinal Cell ◽  
Ocular Diseases ◽  
Wide Range ◽  
Glycation End Products ◽  
Cell Layers ◽  
Proinflammatory Activity ◽  
And Migration ◽  
Proliferation And Migration

High-mobility group box 1 (HMGB1) is a nuclear protein that can also act as an extracellular trigger of inflammation, proliferation, and migration in eye diseases. It induces signaling pathways by binding to the receptor for advanced glycation end products (RAGE) and Toll-like receptors (TLRs) 2, 4, and 9. This proinflammatory activity is considered to be important in the pathogenesis of a wide range of ocular diseases resulting from hemodynamic changes, presence of neovascular endothelial cells, secretion of intraocular immune factors or inflammation, and apoptosis of retinal cell layers. Further work is needed to elucidate in detail how HMGB1 contributes to ocular disease and how its damaging activity can be modulated. In this review, we summarize current knowledge on HMGB1 as a ligand that can evoke inflammation and immune responses in ocular diseases.

scholarly journals Pre-hospital CPR and early REBOA in trauma patients - Results from the ABOTrauma Registry.

2020 ◽  
Author(s):  
Peter Hilbert-Carius ◽  
David T McGreevy ◽  
Fikri M. Abu-Zidan ◽  
Tal M. Hörer
Keyword(s):  
Survival Rate ◽  
Hospital Admission ◽  
Injury Severity ◽  
Balloon Occlusion ◽  
Trauma Patients ◽  
Probability Of Survival ◽  
Traumatic Cardiac Arrest ◽  
Predicted Probability ◽  
Using Data

Abstract Background: Severely injured trauma patients suffering from traumatic cardiac arrest (TCA) and requiring cardiopulmonary resuscitation (CPR) rarely survive. The role of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA) performed early after hospital admission in patients with TCA is not well-defined. As the use of REBOA increases, there is great interest in knowing if there is a survival benefit related to the early use of REBOA after TCA. Using data from the ABOTrauma Registry, we aimed to study the role of REBOA used early after hospital admission in trauma patients who required pre-hospital CPR. Methods: Retrospective and prospective data on the use of REBOA were collected from the ABOTrauma Registry from 11 centers in seven countries globally between 2014 and 2019. In all patients with pre-hospital TCA, the predicted probability of survival, calculated with the Revised Injury Severity Classification II (RISC II), was compared with the observed survival rate. Results: Of 213 patients in the ABOTrauma Registry, 26 patients (12.2%) who had received pre-hospital CPR were identified. The median (range) Injury Severity Score (ISS) was 45.5 (25-75). Fourteen patients (54%) had been admitted to hospital with ongoing CPR. Nine patients (35%) died within the first 24 hours, while seventeen patients (65%) survived post 24 hours. The survival rate to hospital discharge was 27% (n=7). The predicted mortality using the RISC II was 0.977 (25 out of 26). The observed mortality (19 out of 26) was significantly lower than the predicted mortality (p=0.049). Patients not responding to REBOA were more likely to die. Only one (10%) out of 10 non-responders survived. Survival rate in the 16 patients responding to REBOA was 37.5% (n=6). REBOA with a median (range) duration of 45 (8-70) minutes significantly increases blood pressure from median (range) 56.5 (0-147) to 90 (0-200) mmHg. Conclusions: Mortality in patients suffering from TCA and receiving REBOA early after hospital admission is significantly lower than predicted by the RISC II. REBOA may improve survival after TCA. The use of REBOA in these patients should be further investigated.

scholarly journals Digital Curation for Science, Digital Libraries, and Individuals

2008 ◽  
Vol 1 ◽  
pp. 3-16 ◽  
Author(s):  
Neil Beagrie
Keyword(s):  
Digital Libraries ◽  
Digital Information ◽  
Digital Curation ◽  
Wide Range ◽  
Intellectual Assets ◽  
Information Professionals ◽  
Using Data ◽  
Traditional Roles ◽  
Significant Effort ◽  
Digital Assets

The creation, management and use of digital materials are of increasing importance for a wide range of activities. Much of the knowledge base and intellectual assets of institutions and individuals are now in digital form. The term digital curation is increasingly being used for the actions needed to add value to and maintain these digital assets over time for current and future generations of users. The paper explores this emerging field of digital curation as an area of inter-disciplinary research and practice, and the trends which are influencing its development. It analyses the genesis of the term and how traditional roles relating to digital assets are in transition. Finally it explores some of the drivers for curation ranging from trends such as exponential growth in digital information, to "life-caching", digital preservation, the Grid and new opportunities for publishing, sharing, and re-using data. It concludes that significant effort needs to be put into developing a persistent information infrastructure for digital materials and into developing the digital curation skills of researchers and information professionals. Without this, current investment in digitisation and digital content will only secure short-term rather than lasting benefits.

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