Differences between diploid donors are the main contributing factor for subgenome asymmetry measured in either gene ratio or relative diversity in allopolyploids

Genome ◽  
2021 ◽  
Author(s):  
Xueling Ye ◽  
Haiyan Hu ◽  
Hong Zhou ◽  
Yunfeng Jiang ◽  
Shang Gao ◽  
...  
Keyword(s):  
Large Degree ◽  
Diploid Parent ◽  
Polyploid Evolution ◽  
Evolutionary Selection ◽  
Donor Species

Subgenome asymmetry (SA) has routinely been attributed to different responses between the subgenomes of a polyploid to various stimuli during evolution. Here, we compared subgenome differences in gene ratio and relative diversity between artificial and natural genotypes of several allopolyploid species. Surprisingly, consistent differences were detected between these two types of polyploid genotypes although they differ in times exposed to evolutionary selection. The estimated ratio of shared genes between a subgenome and its diploid donor was invariably higher for the artificial allopolyploid genotypes than those for the natural genotypes, which is expected as it is now well-known that many genes in a species are not shared among all individuals. As the exact diploid parent for a given subgenome is unknown, the estimated ratios of shared genes for the natural genotypes would also include difference among individual genotypes of the diploid donor species. Further, we detected the presence of SA in genotypes before the completion of the polyploidization events as well as in those which were not formed via polyploidization. These results indicate that SA may, to a large degree, reflect differences between its diploid donors or that changes occurred during polyploid evolution are defined by their donor genomes.

Characterization of homoepitaxial diamond films by Electron microscopy

1991 ◽  
Vol 49 ◽  
pp. 880-881
Author(s):  
D.P. Malta ◽  
S.A. Willard ◽  
R.A. Rudder ◽  
G.C. Hudson ◽  
J.B. Posthill ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Surface Defects ◽  
Substrate Surface ◽  
Diamond Films ◽  
Chemical Vapor ◽  
Polycrystalline Diamond ◽  
Large Degree ◽  
Rf Plasma ◽  
Semiconducting Diamond

Semiconducting diamond films have the potential for use as a material in which to build active electronic devices capable of operating at high temperatures or in high radiation environments. A major goal of current device-related diamond research is to achieve a high quality epitaxial film on an inexpensive, readily available, non-native substrate. One step in the process of achieving this goal is understanding the nucleation and growth processes of diamond films on diamond substrates. Electron microscopy has already proven invaluable for assessing polycrystalline diamond films grown on nonnative surfaces.The quality of the grown diamond film depends on several factors, one of which is the quality of the diamond substrate. Substrates commercially available today have often been found to have scratched surfaces resulting from the polishing process (Fig. 1a). Electron beam-induced current (EBIC) imaging shows that electrically active sub-surface defects can be present to a large degree (Fig. 1c). Growth of homoepitaxial diamond films by rf plasma-enhanced chemical vapor deposition (PECVD) has been found to planarize the scratched substrate surface (Fig. 1b).

Using Convolutional Neural Networks to measure the contribution of visual features to the representation of object animacy in the brain

2019 ◽  
Author(s):  
Sushrut Thorat
Keyword(s):  
Neural Networks ◽  
Convolutional Neural Networks ◽  
Temporal Cortex ◽  
Large Degree ◽  
Visual Features ◽  
Visual Feature ◽  
Visual Stream ◽  
Feature Information ◽  
Ventral Visual Stream ◽  
Animal Images

A mediolateral gradation in neural responses for images spanning animals to artificial objects is observed in the ventral temporal cortex (VTC). Which information streams drive this organisation is an ongoing debate. Recently, in Proklova et al. (2016), the visual shape and category (“animacy”) dimensions in a set of stimuli were dissociated using a behavioural measure of visual feature information. fMRI responses revealed a neural cluster (extra-visual animacy cluster - xVAC) which encoded category information unexplained by visual feature information, suggesting extra-visual contributions to the organisation in the ventral visual stream. We reassess these findings using Convolutional Neural Networks (CNNs) as models for the ventral visual stream. The visual features developed in the CNN layers can categorise the shape-matched stimuli from Proklova et al. (2016) in contrast to the behavioural measures used in the study. The category organisations in xVAC and VTC are explained to a large degree by the CNN visual feature differences, casting doubt over the suggestion that visual feature differences cannot account for the animacy organisation. To inform the debate further, we designed a set of stimuli with animal images to dissociate the animacy organisation driven by the CNN visual features from the degree of familiarity and agency (thoughtfulness and feelings). Preliminary results from a new fMRI experiment designed to understand the contribution of these non-visual features are presented.

Are local losses of biodiversity causing degraded ecosystem function?

2017 ◽  
Author(s):  
Mark Vellend
Keyword(s):  
Ecosystem Function ◽  
Species Interactions ◽  
Regional Scale ◽  
Temporal Trends ◽  
Biodiversity Loss ◽  
Large Degree ◽  
Global Scale ◽  
Degraded Ecosystem ◽  
Biodiversity Change ◽  
Local Extirpation

This chapter highlights the scale dependence of biodiversity change over time and its consequences for arguments about the instrumental value of biodiversity. While biodiversity is in decline on a global scale, the temporal trends on regional and local scales include cases of biodiversity increase, no change, and decline. Environmental change, anthropogenic or otherwise, causes both local extirpation and colonization of species, and thus turnover in species composition, but not necessarily declines in biodiversity. In some situations, such as plants at the regional scale, human-mediated colonizations have greatly outnumbered extinctions, thus causing a marked increase in species richness. Since the potential influence of biodiversity on ecosystem function and services is mediated to a large degree by local or neighborhood species interactions, these results challenge the generality of the argument that biodiversity loss is putting at risk the ecosystem service benefits people receive from nature.

At the Simla Conference and in the General Elections

2018 ◽  
Author(s):  
J.S. Grewal
Keyword(s):  
Large Degree ◽  
Large Majority ◽  
Degree Of Polarization ◽  
Considerable Proportion ◽  
Executive Council ◽  
Crucial Importance ◽  
The Future ◽  
General Elections ◽  
The Right

On Lord Wavell’s initiative, the Simla Conference was held to discuss the proposal of a new executive council and a new constitution for India after the war. Master Tara Singh represented the Sikh community at the Simla Conference. The Conference failed due to Jinnah’s insistence that the Muslim League alone had the right to nominate Muslim representatives on the Executive Council. The failure of the Conference made the general elections of 1945–6 all the more important. The general elections resulted in a large degree of polarization between the Hindus, Muslims, and Sikhs. The Muslim League got Muslim mandate in favour of Pakistan. The Congress got a mandate of Hindus and a considerable proportion of the Sikhs for independence without partition. The Akalis got support of the large majority of the Sikhs for an independent political entity of the Sikhs. This polarization was of crucial importance for the future.

scholarly journals Optimized CSIDH Implementation Using a 2-Torsion Point

Cryptography ◽  
2020 ◽  
Vol 4 (3) ◽  
pp. 20 ◽  
Author(s):  
Donghoe Heo ◽  
Suhri Kim ◽  
Kisoon Yoon ◽  
Young-Ho Park ◽  
Seokhie Hong
Keyword(s):  
Elliptic Curve ◽  
Group Action ◽  
Large Degree ◽  
Transitive Group ◽  
Optimization Method ◽  
Torsion Point ◽  
Torsion Points ◽  
Diffie Hellman ◽  
Odd Degree ◽  
Montgomery Curve

The implementation of isogeny-based cryptography mainly use Montgomery curves, as they offer fast elliptic curve arithmetic and isogeny computation. However, although Montgomery curves have efficient 3- and 4-isogeny formula, it becomes inefficient when recovering the coefficient of the image curve for large degree isogenies. Because the Commutative Supersingular Isogeny Diffie-Hellman (CSIDH) requires odd-degree isogenies up to at least 587, this inefficiency is the main bottleneck of using a Montgomery curve for CSIDH. In this paper, we present a new optimization method for faster CSIDH protocols entirely on Montgomery curves. To this end, we present a new parameter for CSIDH, in which the three rational two-torsion points exist. By using the proposed parameters, the CSIDH moves around the surface. The curve coefficient of the image curve can be recovered by a two-torsion point. We also proved that the CSIDH while using the proposed parameter guarantees a free and transitive group action. Additionally, we present the implementation result using our method. We demonstrated that our method is 6.4% faster than the original CSIDH. Our works show that quite higher performance of CSIDH is achieved while only using Montgomery curves.

scholarly journals Temperature chaos is present in off-equilibrium spin-glass dynamics

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Marco Baity-Jesi ◽  
Enrico Calore ◽  
Andrés Cruz ◽  
Luis Antonio Fernandez ◽  
José Miguel Gil-Narvion ◽  
...  
Keyword(s):  
Spin Glass ◽  
Dynamic Effect ◽  
Large Degree ◽  
Equilibrium Temperature ◽  
Experimental Conditions ◽  
Temperature Changes ◽  
Equilibrium Dynamics ◽  
Glass Dynamics ◽  
Extreme Sensitivity ◽  
Non Equilibrium

AbstractExperiments featuring non-equilibrium glassy dynamics under temperature changes still await interpretation. There is a widespread feeling that temperature chaos (an extreme sensitivity of the glass to temperature changes) should play a major role but, up to now, this phenomenon has been investigated solely under equilibrium conditions. In fact, the very existence of a chaotic effect in the non-equilibrium dynamics is yet to be established. In this article, we tackle this problem through a large simulation of the 3D Edwards-Anderson model, carried out on the Janus II supercomputer. We find a dynamic effect that closely parallels equilibrium temperature chaos. This dynamic temperature-chaos effect is spatially heterogeneous to a large degree and turns out to be controlled by the spin-glass coherence length ξ. Indeed, an emerging length-scale ξ* rules the crossover from weak (at ξ ≪ ξ*) to strong chaos (ξ ≫ ξ*). Extrapolations of ξ* to relevant experimental conditions are provided.

scholarly journals Analysis of multiple chromosomal rearrangements in the genome of Willisornis vidua using BAC-FISH and chromosome painting on a supposed conserved karyotype

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Talita Fernanda Augusto Ribas ◽  
Julio Cesar Pieczarka ◽  
Darren K. Griffin ◽  
Lucas G. Kiazim ◽  
Cleusa Yoshiko Nagamachi ◽  
...  
Keyword(s):  
Chromosome Painting ◽  
Diploid Number ◽  
Chromosomal Rearrangements ◽  
Large Degree ◽  
Artificial Chromosome ◽  
Gallus Gallus ◽  
Phylogeographic Structure ◽  
Molecular Cytogenetic ◽  
Burhinus Oedicnemus ◽  
Intrachromosomal Rearrangements

Abstract Background Thamnophilidae birds are the result of a monophyletic radiation of insectivorous Passeriformes. They are a diverse group of 225 species and 45 genera and occur in lowlands and lower montane forests of Neotropics. Despite the large degree of diversity seen in this family, just four species of Thamnophilidae have been karyotyped with a diploid number ranging from 76 to 82 chromosomes. The karyotypic relationships within and between Thamnophilidae and another Passeriformes therefore remain poorly understood. Recent studies have identified the occurrence of intrachromosomal rearrangements in Passeriformes using in silico data and molecular cytogenetic tools. These results demonstrate that intrachromosomal rearrangements are more common in birds than previously thought and are likely to contribute to speciation events. With this in mind, we investigate the apparently conserved karyotype of Willisornis vidua, the Xingu Scale-backed Antbird, using a combination of molecular cytogenetic techniques including chromosome painting with probes derived from Gallus gallus (chicken) and Burhinus oedicnemus (stone curlew), combined with Bacterial Artificial Chromosome (BAC) probes derived from the same species. The goal was to investigate the occurrence of rearrangements in an apparently conserved karyotype in order to understand the evolutionary history and taxonomy of this species. In total, 78 BAC probes from the Gallus gallus and Taeniopygia guttata (the Zebra Finch) BAC libraries were tested, of which 40 were derived from Gallus gallus macrochromosomes 1–8, and 38 from microchromosomes 9–28. Results The karyotype is similar to typical Passeriformes karyotypes, with a diploid number of 2n = 80. Our chromosome painting results show that most of the Gallus gallus chromosomes are conserved, except GGA-1, 2 and 4, with some rearrangements identified among macro- and microchromosomes. BAC mapping revealed many intrachromosomal rearrangements, mainly inversions, when comparing Willisornis vidua karyotype with Gallus gallus, and corroborates the fissions revealed by chromosome painting. Conclusions Willisornis vidua presents multiple chromosomal rearrangements despite having a supposed conservative karyotype, demonstrating that our approach using a combination of FISH tools provides a higher resolution than previously obtained by chromosome painting alone. We also show that populations of Willisornis vidua appear conserved from a cytogenetic perspective, despite significant phylogeographic structure.

scholarly journals Capacity in municipalities: Infrastructures, maintenance debts and ways of overcoming a run-to-failure mentality

2021 ◽  
pp. 026909422110304
Author(s):  
Jens Alm ◽  
Alexander Paulsson ◽  
Robert Jonsson
Keyword(s):  
Economies Of Scale ◽  
Heavy Traffic ◽  
Road Networks ◽  
Large Degree ◽  
Welfare States ◽  
The Road ◽  
Technical Capacity ◽  
Multidimensional Concept ◽  
Sewage Systems ◽  
Road Segments

There is a growing maintenance debt of ageing and critical infrastructures in many municipalities in European welfare states. In this article, we use the multidimensional concept of local capacity as a point of departure to analyse how and in what ways Swedish municipalities work with the routine maintenance of infrastructures, including municipal road networks as well as water and sewage systems. For the road networks, maintenance is generally outsourced to contractors and there is also a large degree of tolerance for various standards on different road segments within and between the municipalities. Less used road segments are not as prioritised as those with heavy traffic. For the water and sewage systems, in-house technical capacity is needed as differences in water quality are not tolerated. Economies of scale mean that in-house capacity is translated into the creation of inter-municipal bodies. As different forms of capacities tend to reinforce each other, municipal capacity builds up over time in circular movements. These results add knowledge to current research by pointing to the ways municipalities are overcoming a run-to-failure mentality by building capacity to pay off the infrastructural maintenance debt.

scholarly journals Recent progress understanding pathophysiology and genesis of brain AVM—a narrative review

2021 ◽  
Author(s):  
Hans-Jakob Steiger
Keyword(s):  
Large Degree ◽  
Advanced Imaging ◽  
Genetic Origin ◽  
The Past ◽  
Open Questions ◽  
Brain Avm ◽  
Pubmed Search ◽  
Substantial Progress ◽  
The Individual ◽  
Arterial Aneurysms

AbstractConsiderable progress has been made over the past years to better understand the genetic nature and pathophysiology of brain AVM. For the actual review, a PubMed search was carried out regarding the embryology, inflammation, advanced imaging, and fluid dynamical modeling of brain AVM. Whole-genome sequencing clarified the genetic origin of sporadic and familial AVM to a large degree, although some open questions remain. Advanced MRI and DSA techniques allow for better segmentation of feeding arteries, nidus, and draining veins, as well as the deduction of hemodynamic parameters such as flow and pressure in the individual AVM compartments. Nonetheless, complete modeling of the intranidal flow structure by computed fluid dynamics (CFD) is not possible so far. Substantial progress has been made towards understanding the embryology of brain AVM. In contrast to arterial aneurysms, complete modeling of the intranidal flow and a thorough understanding of the mechanical properties of the AVM nidus are still lacking at the present time.

Sign in / Sign up

Export Citation Format

Share Document