THYROXINE AND INSULIN INTERACTION

1959 ◽  
Vol 37 (1) ◽  
pp. 763-774
Author(s):  
Dorothy S. Dow ◽  
C. E. Allen
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Muscle Mass ◽  
Dna Content ◽  
Body Weight Gain ◽  
Treated Animal ◽  
Hypoglycemic Action ◽  
Young Rat ◽  
The Relationship ◽  
Rna Concentration

Rate of body weight gain of both the young chick and the young rat was markedly inhibited following ingestion of amounts of thyroxine which were greatly in excess of physiological requirements. The rate of body weight gain of the young rat was also markedly inhibited in alloxan diabetes. The administration of insulin partly or largely prevented the observed effect on body weight in both conditions. The administration of thyroxine caused a reduction of rat skeletal muscle mass which was partially prevented when insulin was given concurrently with thyroxine.Reduced body weight gain and muscle mass in the rat were accompanied by marked increases in the muscle DNA and nuclei concentration. Nuclear diameter and the amount of DNA per nucleus remained unchanged. RNA concentration of the muscle was not reduced. The beneficial effect of insulin administration on body weight and muscle mass was accompanied by a preventive effect against changes in muscle DNA and nuclei concentration. However, since the DNA content of muscle bundles remained relatively unchanged and since muscle bundle weights changed proportionately with body weight it would appear that DNA content does not reflect change in muscle mass.The effectiveness of insulin in the thyroxine-treated animal appears to be due to an improved utilization of energy. A hypoglycemic action of thyroxine implies an antagonism between the two hormones in their mechanism of action. The relationship between the two hormones is not direct since the administration of insulin does not affect the increased plasma protein-bound iodine levels resulting from thyroxine treatment.

THYROXINE AND INSULIN INTERACTION

1959 ◽  
Vol 37 (6) ◽  
pp. 763-774 ◽  
Author(s):  
Dorothy S. Dow ◽  
C. E. Allen
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Muscle Mass ◽  
Dna Content ◽  
Body Weight Gain ◽  
Treated Animal ◽  
Hypoglycemic Action ◽  
Young Rat ◽  
The Relationship ◽  
Rna Concentration

Rate of body weight gain of both the young chick and the young rat was markedly inhibited following ingestion of amounts of thyroxine which were greatly in excess of physiological requirements. The rate of body weight gain of the young rat was also markedly inhibited in alloxan diabetes. The administration of insulin partly or largely prevented the observed effect on body weight in both conditions. The administration of thyroxine caused a reduction of rat skeletal muscle mass which was partially prevented when insulin was given concurrently with thyroxine.Reduced body weight gain and muscle mass in the rat were accompanied by marked increases in the muscle DNA and nuclei concentration. Nuclear diameter and the amount of DNA per nucleus remained unchanged. RNA concentration of the muscle was not reduced. The beneficial effect of insulin administration on body weight and muscle mass was accompanied by a preventive effect against changes in muscle DNA and nuclei concentration. However, since the DNA content of muscle bundles remained relatively unchanged and since muscle bundle weights changed proportionately with body weight it would appear that DNA content does not reflect change in muscle mass.The effectiveness of insulin in the thyroxine-treated animal appears to be due to an improved utilization of energy. A hypoglycemic action of thyroxine implies an antagonism between the two hormones in their mechanism of action. The relationship between the two hormones is not direct since the administration of insulin does not affect the increased plasma protein-bound iodine levels resulting from thyroxine treatment.

scholarly journals Physical activity and 4-year changes in body weight in 52,498 non-obese people: The Lifelines Cohort

2020 ◽  
Author(s):  
Oyuntugs Byambasukh ◽  
Petra Vinke ◽  
Daan Kromhout ◽  
Gerjan Navis ◽  
Eva Corpeleijn
Keyword(s):  
Physical Activity ◽  
Body Weight ◽  
Weight Gain ◽  
Muscle Mass ◽  
Leisure Time ◽  
Leisure Time Physical Activity ◽  
Body Weight Gain ◽  
Average Weight ◽  
Obese People ◽  
Average Weight Gain

Abstract Objectives: We investigated associations between leisure-time physical activity (LTPA) at different intensities (moderate and vigorous or moderate-to-vigorous) and prospective weight gain in non-obese people. We also examined whether these associations were independent of other lifestyle factors and changes in muscle mass and whether they were age-dependent and changed over a person’s life course.Methods: The data were extracted from the Lifelines cohort study (N=52,498; 43.5% men) and excluded obese individuals (BMI>30kg/m2). We used the validated SQUASH questionnaire to estimate moderate-to-vigorous (MVPA; MET≥4), moderate (MPA; MET between 4 and 6.5) and vigorous PA (VPA; MET≥6.5). Body weight was objectively measured, and changes were standardized to a 4-year period. Separate analyses, adjusted for age, educational level, diet, smoking, alcohol consumption and changes in creatinine excretion (a marker of muscle mass), were performed for men and women.Results: The average weight gain was +0.45±0.03 kg in women. Relative to each reference groups (No-MVPA, No-MPA and No-VPA), MVPA (Beta (95%CI): -0.34 kg (-0.56;-0.13)), MPA (-0.32 kg (-0.54;-0.10)) and VPA (-0.30 kg (-0.43;-0.18)) were associated with less gain in body weight in women after adjusting for potential confounders, described above. These associations were dose-dependent when physically active individuals were divided in tertiles. Beta-coefficients (95%CI) for the lowest, middle, and highest MVPA tertiles relative to the ‘No-MVPA’ were, respectively, -0.24 (-0.47;-0.02), -0.31 (-0.53;-0.08), and -0.38 (-0.61;-0.16) kg. The average weight gain in men was +0.13±0.03 kg, and only VPA, not MPA was associated with less body weight gain. Beta-coefficients (95%CI) for the VPA tertiles relative to the ‘No-VPA’ group were, respectively, -0.25 (-0.42;-0.09), -0.19 (-0.38;-0.01) and -0.20 (-0.38;-0.02) kg. However, after adjusting for potential confounders, the association was no longer significant in men. The potential benefits of leisure-time PA were age-stratified and mainly observed in younger adults (men: <35 years; women: <55 years). Moreover, occupational MVPA was not associated with favourable changes in body weight in males and females.Conclusion: Higher leisure-time MVPA, MPA, and VPA were associated with less weight gain in women <55 years. In younger men (<35 years), only VPA was associated with less weight gain.

Effect of energy intake on the performance of different types of pig from 45 to 100 kg body weight. 2. Tissue gain

1996 ◽  
Vol 63 (2) ◽  
pp. 289-296 ◽  
Author(s):  
N. Quiniou ◽  
J. Noblet ◽  
J.-Y. Dourmad
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Energy Intake ◽  
Body Weight Gain ◽  
Energy Levels ◽  
Metabolizable Energy ◽  
Large White ◽  
Different Types ◽  
Ad Libitum ◽  
The Relationship

AbstractThe effect of energy supply on physical composition of body weight gain between 45 and 100 kg was studied in Large White castrated males (cLW), crossbred Pietrain × Large White castrated males (cPPX) and boars (bPPX). The pigs were either given food ad libitum and kept in individual pens in experiment 1, or allocated to four energy levels (0·70, 0·80, 0·90, and 1·00 ad libitum) and kept in metabolism cages in experiment 2. Daily protein supplies were calculated to be the same at the four energy levels within each type of pig and non-limiting for growth. Five additional animals for each type of pig were slaughtered at 45 kg. Daily tissue gain was measured according to the comparative slaughter technique. The daily lean gain increased with metabolizable energy (ME) intake according to a linear-plateau relationship whereas the daily fat gain increased linearly. The type of pig significantly affected the slope of the relationship between lean gain and ME intake (from 15 to 22 g per extra MJ ME) but not the slope of the relationship between fat gain and ME intake (10 g per extra MJ ME on average). Increased energy intake was associated with increased fatness of body-weight gain, which was higher in cLW and cPP× than in bPP×.

The influence of level of concentrate feeding on the voluntary intake of grass and on live-weight gain by cattle

1972 ◽  
Vol 14 (1) ◽  
pp. 85-96 ◽  
Author(s):  
J. C. Tayler ◽  
J. M. Wilkinson
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Body Weight Gain ◽  
Live Weight ◽  
Linear Increase ◽  
Live Weight Gain ◽  
Feeding Experiments ◽  
Gut Fill ◽  
Stocking Rates ◽  
The Relationship

SUMMARYGrazing and stall-feeding experiments were conducted to examine the effect of giving different amounts of cereal-protein concentrate with grass on the live-weight gain of cattle initially 6 months of age. The effect of level of concentrate on grass intake was also studied in the indoor trial. Experiment 1 took place at pasture, with two stocking rates (high and low) and three levels of supplementation at each stocking rate. The response to supplementation, and rate of live-weight gain by the unsupplemented groups was similar at both stocking rates for a 101-day period from late April to mid-August. The results are discussed in relation to other pasture supplementation experiments, and to those obtained in the indoor experiment. Experiment 2 (stall-feeding) consisted of five levels of concentrate feeding from zero to 100% of the diet. There was little increase in total intake as the proportion of concentrate in the diet increased, and the relationship between grass intake and concentrate intake was rectilinear.Gut fill estimates are presented for each level of concentrate feeding, and results for empty body-weight gain are discussed in relation to live-weight gains. There was a linear increase in weight gain with increasing proportion of concentrate in the diet. Empty body-weight gain is recommended as a less biased assessment of the response of cattle to concentrates given with pasture or forages.

scholarly journals Physical activity and 4-year changes in body weight in 52,498 non-obese people: The Lifelines Cohort

2020 ◽  
Author(s):  
Oyuntugs Byambasukh ◽  
Petra Vinke ◽  
Daan Kromhout ◽  
Gerjan Navis ◽  
Eva Corpeleijn
Keyword(s):  
Physical Activity ◽  
Body Weight ◽  
Weight Gain ◽  
Muscle Mass ◽  
Body Weight Gain ◽  
Average Weight ◽  
Obese People ◽  
Physically Active ◽  
Younger Men ◽  
Average Weight Gain

Abstract Objectives: We investigated associations between daily-life physical activity (PA) and prospective weight gain in non-obese people. We also examined whether these associations were independent of other lifestyle factors and changes in muscle mass and whether they were age-dependent and changed over a person’s life course. Methods: The data were extracted from the Lifelines cohort study (N=52,498; 43.5% men) and excluded obese individuals (BMI>30kg/m 2 ). We used the validated SQUASH questionnaire to estimate moderate-to-vigorous (MVPA; MET≥4), moderate (MPA; MET between 4 and 6.5) and vigorous PA (VPA; MET≥6.5) within non-occupational (commuting and leisure) and occupational domains. Body weight was objectively measured and changes were standardized to a 4-year period. Separate analyses, adjusted for age, educational level, diet, smoking, alcohol consumption and changes in creatinine excretion (a marker of muscle mass), were performed for men and women. Results: The average weight gain was +0.45±0.03 kg in women. Relative to each reference groups (No-MVPA, No-MPA and No-VPA), non-occupational MVPA (Beta (95%CI): -0.34 kg (-0.56;-0.13)), MPA (-0.32 kg (-0.54;-0.10)) and VPA (-0.30 kg (-0.43;-0.18)) were associated with less gain in body weight in women after adjusting for potential confounders, described above. These associations were dose-dependent when physically active individuals were divided in tertiles. Beta-coefficients (95%CI) for the lowest, middle, and highest MVPA tertiles relative to the ‘No-MVPA’ were, respectively, -0.24 (-0.47;-0.02), -0.31 (-0.53;-0.08), and -0.38 (-0.61;-0.16) kg. The average weight gain in men was +0.13±0.03 kg, and only non-occupational VPA was associated with less body weight gain. Beta-coefficients (95%CI) for the VPA tertiles relative to the ‘No-VPA’ group were, respectively, -0.25 (-0.42;-0.09), -0.19 (-0.38;-0.01) and -0.20 (-0.38;-0.02) kg. However, after adjusting for potential confounders, the association was no longer significant in men. The potential benefits of non-occupational PA were age-stratified and mainly observed in younger adults (men: <35 years; women: <55 years). Moreover, occupational MVPA was not associated with favourable changes in body weight in males and females. Conclusion: Higher non-occupational MVPA, MPA, and VPA were associated with less weight gain in women <55 years. In younger men (<35 years), only non-occupational VPA was associated with less weight gain.

scholarly journals Karakteristik Kuantitatif Sapi Bali dan Sapi Simbal (Simmental X Bali) di Kecamatan Renah Pamenang Kabupaten Merangin

2021 ◽  
Vol 11 (1) ◽  
pp. 30
Author(s):  
Husni Almakmum ◽  
Depison Depison ◽  
Helmi Ediyanto
Keyword(s):  
Body Weight ◽  
Body Size ◽  
Weight Gain ◽  
Body Weight Gain ◽  
The Body ◽  
Chest Circumference ◽  
Body Measurements ◽  
Quantitative Characteristics ◽  
Bali Cattle ◽  
The Relationship

Abstract This study aimed to determine the quantitative characteristics, the determinant of body size and shape, and the correlation of body measurements and the bodyweight of Bali and Simbal cattle in Renah Pamenang, Merangin District. The survey method was used along with purposive sampling, the samples were Bali and Simbal cattle aged I1 (Incicivus 1) and not in pregnant condition, with 60 cattle consisting of 30 males and 30 females. Observed data included: body weight, body weight gain, body length, shoulder height, chest circumference, chest weight, chest width, hip height, and canon circumference were analyzed using the t-test method. The principal component analysis was used to determine the determinant of size and shape of Bali and Simbal cattle followed by the regression and correlation analysis to determine the relationship and closeness of the relationship between body measurements with body weight. The result showed that the body weight, body weight gain, and body size of Bali cattle were significantly different (P <0.05) from Simbal. The body weight, body weight gain, and body size of Bali cattle were lower than Simbal cattle. The main characteristic of size in Bali and Simbal cattle was the Chest Circumference. The dominant characteristic of shape in Bali and Simbal cattle was shoulder height. The highest correlation between body measurements and body weight in Bali and Simbal cattle was the chest circumference. Keywords: Quantitative Characteristics; Bali Cattle; Simbal Cattle.   Abstrak Penelitian ini bertujuan untuk mengetahui karakteristik kuantitatif, penciri ukuran dan bentuk tubuh, serta korelasi ukuran-ukuran tubuh dengan bobot badan sapi Bali dan Simbal di Kecamatan Renah Pamenang Kabupaten Merangin. Metode yang digunakan adalah survey dengan pengambilan sampel secara purposive sampling, yaitu sapi Bali dan Simbal, umur I1 (Incicivus 1),  dan tidak dalam keadaan bunting sebanyak 60 sampel yang terdiri dari 30 ekor jantan dan 30 ekor betina pada masing-masing bangsa. Data yang dihimpun meliputi : bobot badan, pertambahan bobot badan, panjang badan, tinggi pundak, lingkar dada, dalam  dada, lebar dada, tinggi pinggul dan lingkar kanon dianalisis menggunakan uji-t. Analisis komponen utama digunakan untuk mengetahui penciri ukuran dan bentuk tubuh sapi Bali dan Simbal kemudian dilanjutkan analisis regresi dan korelasi untuk mengetahui hubungan dan keeratan hubungan antara ukuran-ukuran tubuh dengan bobot badan. Hasil penelitian menunjukkan bahwa bobot badan, pertambahan bobot badan dan ukuran-ukuran tubuh sapi Bali berbeda nyata (P<0,05) dengan Simbal. Bobot badan, pertambahan bobot badan dan ukuran-ukuran tubuh sapi Bali lebih rendah dibandingkan Simbal. Penciri ukuran pada sapi Bali dan Simbal adalah lingkar dada. penciri bentuk pada sapi Bali dan Simbal adalah tinggi pundak. Korelasi tertinggi antara ukuran-ukuran tubuh dengan bobot badan sapi Bali dan Simbal adalah lingkar dada. Kata kunci: Karakteristik kuantitatif; Sapi Bali; Sapi Simbal

Glutathione peroxidase and selenium in sheep. II.* The relationship between glutathione peroxidase and selenium-responsive unthriftiness in Merino lambs

1979 ◽  
Vol 30 (4) ◽  
pp. 703 ◽  
Author(s):  
DI Paynter ◽  
JW Anderson ◽  
JW McDonald
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Glutathione Peroxidase ◽  
Peroxidase Activity ◽  
Body Weight Gain ◽  
Selenium Status ◽  
Glutathione Peroxidase Activity ◽  
Central Victoria ◽  
Selenium Treatment ◽  
The Relationship

Low erythrocyte activities of the selenium-containing enzyme glutathione peroxidase were found in Merino lambs in an area of the Strathbogie Ranges in central Victoria where selenium-responsive conditions have previously been reported. Body weight gain trials conducted over 10 properties in the above area demonstrated that the severity of selenium-responsive unthriftiness was significantly correlated with the erythrocyte glutathione peroxidase activity (r = – 0.95, P <: 0.001). Positive body weight responses to selenium treatment were only observed in lambs with erythrocyte glutathione peroxidase activities less than 30 U/g Hb prior to selenium treatment. These findings indicate that measurement of erythrocyte glutathione peroxidase activity provides a convenient index of the selenium status in sheep. ________________ *Part I, Aust. J. Agric. Res., 30: 695 (1979).

scholarly journals HUBUNGAN BOBOT LAHIR ANAK BABI DENGAN PERTAMBAHAN BOBOT BADAN, BOBOT SAPIH, MORTALITAS, DAN LITTER SIZE SAPIHAN PADA PETERNAKAN PT. KARYA PROSPEK SATWA

ZOOTEC ◽  
2020 ◽  
Vol 40 (1) ◽  
pp. 260
Author(s):  
Debora K.I. Bunok ◽  
M.Th.R. Lapian ◽  
V.R.W. Rawung ◽  
G.D.G. Rembet
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Birth Weight ◽  
Litter Size ◽  
Body Weight Gain ◽  
Animal Husbandry ◽  
Weaning Weight ◽  
Close Relationship ◽  
Relationship Of ◽  
The Relationship

RELATIONSHIP OF WEIGHT BIRTH PIGLET WITH ADDITION OF AGENCY WEIGHT, WEANING WEIGHT, MORTALITY, AND LITTER SIZE WEANING IN LIVESTOCK PT. KARYA PROSPEK SATWA. This study aims to determine how much the relationship of birth weight with weight gain, weaning weight, mortality, and litter size of weaning in animal husbandry companies owned by Animal Prospects. The material used is 7 pregnant sows from Yorkshire and Landrace, with an average body weight of 140 kg which will be taken by 54 children randomly. Furthermore, this research data obtained from weighing piglets during parturition, weighing weekly during weaning and weighing when weaned and taking data on live and dead piglets during the study. The data is then processed by procentage descriptive method and evaluated by simple correlation (r) and determination (R) tests. The variables measured in the study were body weight gain, weaning weight, mortality, and weaning litter size. Birth weight has a very close relationship with weight gain and weaning weight, but litter size weaning has a very weak relation. While mortality is not related. Key words: Piglets, Birth weight, Weight gain, Weaning weight, Mortality, Litter size weaning.

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