AUTOMATED DIAGNOSIS OF BRAIN TUMOURS ASTROCYTOMAS USING PROBABILISTIC NEURAL NETWORK CLUSTERING AND SUPPORT VECTOR MACHINES
2005 ◽
Vol 15
(01n02)
◽
pp. 1-11
◽
Keyword(s):
A computer-aided diagnosis system was developed for assisting brain astrocytomas malignancy grading. Microscopy images from 140 astrocytic biopsies were digitized and cell nuclei were automatically segmented using a Probabilistic Neural Network pixel-based clustering algorithm. A decision tree classification scheme was constructed to discriminate low, intermediate and high-grade tumours by analyzing nuclear features extracted from segmented nuclei with a Support Vector Machine classifier. Nuclei were segmented with an average accuracy of 86.5%. Low, intermediate, and high-grade tumours were identified with 95%, 88.3%, and 91% accuracies respectively. The proposed algorithm could be used as a second opinion tool for the histopathologists.
Keyword(s):
2012 ◽
Vol 263-266
◽
pp. 2173-2178
2005 ◽
2020 ◽
2019 ◽
Vol 8
(10)
◽
pp. 3664-3667
◽
2020 ◽
2012 ◽
Vol 3
(1)
◽
pp. 91-94