PIXE ANALYSIS OF TRACE ELEMENTS IN SERUM AND HAIR OF PATIENTS WITH BRAIN TUMORS

1993 ◽  
Vol 03 (02) ◽  
pp. 103-108 ◽  
Author(s):  
CHENGJUN MA ◽  
ZHONGLI YIN ◽  
JIFANG HAO ◽  
XINZHOU JIONG ◽  
QIONG SU ◽  
...  
Keyword(s):  
Trace Elements ◽  
Brain Tumors ◽  
Trace Element ◽  
Clinical Importance ◽  
Healthy People ◽  
Pixe Analysis ◽  
Experimental Procedure

This investigation describes results of measurements of trace element distributions in serum and hair obtained from 30 patients with brain tumors. The experimental procedure is also described in this article. The results show that the contents of Zn, Fe and Sr in serum are lower compared to those of healthy people (p<0.01, p<0.05 and p<0.05). The contents of Ca, Cu, Sr and Zn in hair are decreased compared to healthy people (p<0.01 and p<0.05), while the contents of Cr and Fe in hair are higher by 2 times and 1.8 times (p<0.01), respectively. The results above might be of clinical importance.

DETERMINATION OF TRACE ELEMENTS IN HUMAN SALIVA BY PIXE TECHNIQUE

1996 ◽  
Vol 06 (01n02) ◽  
pp. 273-276 ◽  
Author(s):  
P. HATAMI ◽  
H. PEYROVAN ◽  
H. AFARIDEH ◽  
S. SHOJAEI
Keyword(s):  
Trace Elements ◽  
Healthy Volunteers ◽  
Trace Element ◽  
Element Concentration ◽  
Trace Element Concentration ◽  
Human Saliva ◽  
Normal Range ◽  
Pixe Analysis ◽  
X Ray

Mineral trace element concentration of human saliva from healthy volunteers, were investigated by Proton-Induced X-ray Emission (PIXE) analysis. The specimens were bombarded with Proton beams of 2 MeV from a Van de Graaff accelerator at NRC . The object of this measurement was to find a normal range of trace element concentration for Iranian people.

scholarly journals Association of antiepileptic drug usage, trace elements and thyroid hormone status

2016 ◽  
Vol 174 (4) ◽  
pp. 425-432 ◽  
Author(s):  
Chantal Zevenbergen ◽  
Tim I M Korevaar ◽  
Andrea Schuette ◽  
Robin P Peeters ◽  
Marco Medici ◽  
...  
Keyword(s):  
Trace Elements ◽  
Thyroid Hormone ◽  
Trace Element ◽  
Clinical Importance ◽  
Psychomotor Retardation ◽  
Thyroid Stimulating Hormone ◽  
Linear Regression Models ◽  
Drug Usage ◽  
Negatively Associated ◽  
Trace Element Levels

BackgroundLevels of thyroid hormone (TH) and trace elements (copper (Cu) and selenium (Se)) are important for development and function of the brain. Anti-epileptic drugs (AEDs) can influence serum TH and trace element levels. As the relationship between AEDs, THs, and trace elements has not yet been studied directly, we explored these interactions.MethodIn total 898 participants, from the Thyroid Origin of Psychomotor Retardation study designed to investigate thyroid parameters in subjects with intellectual disability (ID), had data available on serum Se, Cu, thyroid stimulating hormone (TSH), free thyroxine (FT4), tri-iodothyronine (T3), reverse T3, T4, and thyroxine-binding globulin (TBG); 401 subjects were on AED treatment. Differences in trace elements according to medication usage was investigated using ANOVA, and associations between trace elements and thyroid parameters were analysed using (non-) linear regression models.ResultsStudy participants were not deficient in any of the trace elements analyzed. AED (carbamazepine, valproate and phenytoin) usage was negatively associated with serum Se and showed compound-specific associations with Cu levels. After correction for drug usage, Se was positively associated with TSH levels, negatively associated with FT4levels, and positively with T3levels. Cu was positively associated with T4, T3, and rT3, which was largely dependent on TBG levels.ConclusionThe subjects with ID did not display profound deficiencies in trace element levels. AEDs were associated with serum Se and Cu levels, while serum Se and Cu were also associated with thyroid parameters. Further studies on the underlying mechanisms and potential clinical importance are warranted.

PIXE ANALYSIS OF TRACE ELEMENTS IN CLAM SHELLS MARKED WITH IRON RUSTING

1996 ◽  
Vol 06 (03n04) ◽  
pp. 517-522 ◽  
Author(s):  
YOSHINORI KOSHIKAWA ◽  
NOBUAKI ARAI ◽  
WATARU SAKAMOTO ◽  
KOJI YOSHIDA
Keyword(s):  
Trace Elements ◽  
Trace Element ◽  
Intensity Ratio ◽  
Ruditapes Philippinarum ◽  
Pixe Analysis ◽  
X Ray ◽  
Elemental Concentrations ◽  
Element Concentrations ◽  
Pixe Method

Trace element concentrations in short necked clam Ruditapes philippinarum marked shells with iron rusting were determined by particle induced X-ray emission (PIXE) method. Element such as Ca, Mn, Fe, Zn, Sr, and Br were detected in the shells. The Fe/Ca X-ray intensity ratio decreased exponentially on the day after marking. It was concluded that the higher Fe concentration on marked clams was caused by attached iron rusting. The concentrations of Fe, Br, and Sr differed among the 3 stations (Kamaya, Shigaki, and Iwatani), suggesting that elemental concentrations may be related to the growth of clams.

Elemental Analysis of Biomedical Samples by Pixe

1977 ◽  
Vol 21 ◽  
pp. 261-266
Author(s):  
J. A. Guffey ◽  
H. A. Van Rinsvelt ◽  
W. R. Adams ◽  
R. M. Sarper ◽  
Z. Karcioglu ◽  
...  
Keyword(s):  
Trace Elements ◽  
Early Detection ◽  
Trace Element ◽  
Elemental Analysis ◽  
Diagnostic Tool ◽  
Trace Element Analysis ◽  
Analytical Tool ◽  
Element Analysis ◽  
Pixe Analysis ◽  
X Ray

The use of particle-induced X-ray emission (PIXE) analysis as a standard analytical tool in the study of trace elements is well known. In the present investigation, an attempt is made to correlate human diseases with the presence or absence of trace elements and/or the changes in their concentration in healthy and diseased tissues. If such correlations do actually exist, trace element analysis could certainly be used as a diagnostic tool for the early detection of diseases and there is considerable interest in such information.

TRACE ELEMENT ANALYSIS IN ANTS COLLECTED IN JAPAN, FINLAND AND SWEDEN

1992 ◽  
Vol 02 (03) ◽  
pp. 405-411 ◽  
Author(s):  
K. KITAO
Keyword(s):  
Trace Elements ◽  
Trace Element ◽  
Trace Element Analysis ◽  
Reasonable Accuracy ◽  
Element Analysis ◽  
Pixe Analysis ◽  
X Ray ◽  
Minor Elements ◽  
Analytical Results ◽  
Pixe Method

Particle induced x-ray emission has been used to determine the concentration of trace elements in ants (Formicidae). Scanning PIXE analysis was also used to determine the distribution of these elements. Samples of ants were collected from gardens, buildings or from the roadway in Japan, Finland and Sweden. The only pre-treatments were dusting and washing. In each run of experiments we used only one individual ant and have obtained the analytical results of a reasonable accuracy. We have detected chemical minor elements, i.e., Mn, Fe, Cu, Zn, Rb, Br and Sr. The PIXE, and scanning PIXE method proved to be useful and sensitive enough to measure trace elements in such small insects as ants.

Methylmercury and Trace Element Distribution in the Organs of Stenella coeruleoalba Dolphins Stranded on the French Mediterranean Coast

2014 ◽  
Vol 8 (1) ◽  
pp. 35-48 ◽  
Author(s):  
Emmanuel Wafo ◽  
Véronique Risoul ◽  
Thérèse Schembri ◽  
Véronique Lagadec ◽  
Frank Dhermain ◽  
...  
Keyword(s):  
Trace Elements ◽  
Trace Element ◽  
Marine Pollution ◽  
Element Distribution ◽  
Mediterranean Coast ◽  
Trace Element Distribution ◽  
Slight Reduction ◽  
Stenella Coeruleoalba ◽  
Contamination Levels

The main objective of this study was to evaluate the contamination by mercury (Hg), methylmercury (Me-Hg), cadmium (Cd), selenium (Se), zinc (Zn), copper (Cu), iron (Fe) and manganese (Mn) in dolphins stranded on the French Mediterranean coast. The distributions of these contaminants in the organs of dolphins have also been studied. Overall, contamination levels varied according to the following sequence: liver > kidney > lung > muscle, except for cadmium (kidney > liver > lung > muscle). Size and sex of animals were also considered. Young dolphins were less impacted with trace elements than adults, except for copper. Among the studied parameters, the most important appeared to be the size of mammals. In addition, in the case of mercury and selenium, the sex of mammals seemed to be also relevant. The correlations between the concentrations of trace elements suggest the existence of detoxification processes. Since 1990s, using dolphins for tracing marine pollution, a slight reduction in the burden of the considered trace elements could be noted.

scholarly journals Spatial distribution and potential ecological risk assessment of some trace elements in sediments and grey mangrove (Avicennia marina) along the Arabian Gulf coast, Saudi Arabia

2020 ◽  
Vol 18 (1) ◽  
pp. 77-96
Author(s):  
Hameed Alsamadany ◽  
Hassan S. Al-Zahrani ◽  
El-Metwally M. Selim ◽  
Mohsen M. El-Sherbiny
Keyword(s):  
Trace Elements ◽  
Trace Element ◽  
Ecological Risk ◽  
Oil Pollution ◽  
Gulf Coast ◽  
Arabian Gulf ◽  
Avicennia Marina ◽  
Potential Ecological Risk ◽  
Average Concentration ◽  
Grey Mangrove

AbstractTo assess trace element concentrations (Zn, Cu, Pb, Cr, Cd and Ni) in the mangrove swamps along the Saudi coast of the Arabian Gulf, thirteen samples of surface sediment and leaves of grey mangrove, Avicennia marina were collected and analyzed. The detected trace element contents (μg g-1) in surface sediments were in the following descending order according to their mean values; Cr (49.18) > Zn (48.48) > Cu (43.06) > Pb (26.61) > Ni (22.88) > Cd (3.21). The results showed that the average concentrations of Cd and Pb exceeded their world average concentration of shale. The geo-accumulation, potential ecological risk and toxicity response indices demonstrated that trace elements have posed a considerable ecological risk, especially Cd. The inter-relationships between physico-chemical characters and trace elements suggests that grained particles of mud represent a noteworthy character in the distribution of trace elements compared to organic materials. Moreover, the results revealed that Zn was clearly bioaccumulated in leaf tissues A. marina. Dredging, landfilling, sewage effluents and oil pollution can be the paramount sources of pollution in the area under investigation.

scholarly journals Vitamin Analysis, Trace Elements Content, and Their Extractabilities in Tetrapleura tetraptera

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Prince Oteng ◽  
John K. Otchere ◽  
Stephen Adusei ◽  
Richard Q. Mensah ◽  
Emmanuel Tei-Mensah
Keyword(s):  
Trace Elements ◽  
Vitamin A ◽  
Vitamin C ◽  
Trace Element ◽  
Trace Element Content ◽  
Beta Carotene ◽  
Flame Atomic Absorption ◽  
Significant Difference ◽  
Tetrapleura Tetraptera ◽  
Vitamin Analysis

Tetrapleura tetraptera is widely cherished in African traditional homes because of its alleged therapeutic and nutritional properties. This present study aimed at determining the levels of vitamin A, C, E, and beta-carotene and trace element (Fe, Cu, Mn, Co, Se, and Zn) concentrations and their extractabilities in the pulp, seeds, and whole fruit (mixture of pulp and seeds) of T. tetraptera. The total trace element concentration of Fe, Cu, Co, Mn, and Zn and their extractabilities (%) were determined using flame atomic absorption spectrometer (FAAS), whereas UV-VIS spectrophotometer was used to determine selenium concentration. The trace element content (mg/kg) based on dry weight in the pulp, seeds, and whole fruit was Fe (162.00 ± 7.14, 115.00 ± 12.00, and 154.00 ± 25.20, respectively), Zn (31.60 ± 4.77, 43.40 ± 5.29, and 41.50 ± 8.97, respectively), Cu (16.10 ± 4.98, 11.90 ± 8.40, and 17.20 ± 14.50, respectively), Mn (55.30 ± 2.41, 156.00 ± 10.20, and 122.00 ± 5.29, respectively), Co (38.10 ± 6.40, 21.10 ± 7.15, and 44.00 ± 14.90, respectively), and Se (1.49 ± 0.17, 2.43 ± 0.28, and 2.97 ± 0.27 μg/g, respectively). The mineral extractabilities (%) in the pulp, seeds, and whole fruit of T. tetraptera were established to be in the order Co > Zn > Fe > Cu > Se > Mn. Also, the chromatographic method (HPLC) was used to evaluate vitamin E concentration, and vitamin C and concentration of beta-carotene were calculated from the obtained concentration of vitamin A using a conversion factor by the titrimetric method. From the results of vitamin analysis, a significant difference (p<0.05) was observed among the pulp, seeds, and whole fruit for vitamin C and E. However, no significant difference (p>0.05) was perceived among these plant parts for vitamin A and beta-carotene. This study has therefore revealed that the pulp, seeds, and whole fruit of T. tetraptera contain varying concentrations of vitamins and trace elements and has given many vital insights on which part of T. tetraptera to consume, as concentrations of these nutrients differ in the discrete parts of the fruit.

scholarly journals Comparative Genomics of Trace Element Dependence in Biology

2011 ◽  
Vol 286 (27) ◽  
pp. 23623-23629 ◽  
Author(s):  
Yan Zhang ◽  
Vadim N. Gladyshev
Keyword(s):  
Trace Elements ◽  
Comparative Genomics ◽  
Trace Element ◽  
Evolutionary Dynamics ◽  
Protein Families ◽  
Fundamental Properties ◽  
Recent Advances ◽  
Living Organisms ◽  
Zinc Protein

Biological trace elements are needed in small quantities but are used by all living organisms. A growing list of trace element-dependent proteins and trace element utilization pathways highlights the importance of these elements for life. In this minireview, we focus on recent advances in comparative genomics of trace elements and explore the evolutionary dynamics of the dependence of user proteins on these elements. Many zinc protein families evolved representatives that lack this metal, whereas selenocysteine in proteins is dynamically exchanged with cysteine. Several other elements, such as molybdenum and nickel, have a limited number of user protein families, but they are strictly dependent on these metals. Comparative genomics of trace elements provides a foundation for investigating the fundamental properties, functions, and evolutionary dynamics of trace element dependence in biology.

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