Acupuncture and Traditional Herbal Medicine Therapy Prevent Deliriumin Patients with Cardiovascular Disease in Intensive Care Units

2017 ◽  
Vol 45 (02) ◽  
pp. 255-268 ◽  
Author(s):  
Jun Matsumoto-Miyazaki ◽  
Hiroaki Ushikoshi ◽  
Shusaku Miyata ◽  
Nagisa Miyazaki ◽  
Takahide Nawa ◽  
...  
Keyword(s):  
Intensive Care ◽  
Treatment Group ◽  
Herbal Medicine ◽  
Combination Therapy ◽  
Incidence Rate ◽  
Control Period ◽  
Control Group ◽  
Large Sample Size ◽  
Traditional Herbal Medicine ◽  
Cv Disease

The aim of this study was to determine the effect of combination therapy consisting of acupuncture and traditional herbal medicine (Kampo medicine) for reducing the incidence rate of delirium in patients with cardiovascular (CV) disease in ICUs. Twenty-nine patients who had been urgently admitted to the ICU in the control period were treated with conventional intensive care. Thirty patients in the treatment period received conventional therapy plus a combination therapy consisting of acupuncture and herbal medicine. Acupuncture treatment was performed once a day, and the herbal formula was administered orally three times a day during the first week of the ICU stay. The standard acupuncture points were GV20, Ex-HN3, HT7, LI4, Liv3, and KI3, and the main herbal preparation was Kamikihito. The incident rates of delirium, assessed using the confusion assessment method for ICU, in the treatment and control period were compared. The incidence rate of delirium was significantly lower in the treatment group than in the control group (6.6% vs. 37.9%, [Formula: see text]). Moreover, sedative drugs and non-pharmacological approaches against aggressive behavior of patients who were delirious were used less in the treatment group than in the control group. No serious adverse events were observed in the treatment group. Combination therapy consisting of acupuncture and herbal medicine was found to be effective in lowering the incidence of delirium in patients with CV disease in ICUs. Further studies with a large sample size and parallel randomized controlled design would be required to establish the effects of this therapy.

Effect of Pressure Injury Prevention Guides Used In a Pediatric Intensive Care

2019 ◽  
Vol 29 (4) ◽  
pp. 249-255
Author(s):  
Gülzade Uysal ◽  
Duygu Sönmez Düzkaya ◽  
Tülay Yakut ◽  
Gülçin Bozkurt
Keyword(s):  
Intensive Care ◽  
Treatment Group ◽  
Injury Prevention ◽  
Intervention Group ◽  
Pediatric Intensive Care ◽  
Control Group ◽  
Post Intervention ◽  
Significant Difference ◽  
Pressure Injury ◽  
Pressure Injury Prevention

The aim of this study was to determine the effectiveness of a pressure injury prevention guide used in a pediatric intensive care unit (PICU) on the occurrence of pressure injuries. The design is a pre-post intervention with a control group and a prospective intervention group. Pressure injuries occurred on 9.4% of children in the nontreatment group, and in 3.6% of children in the treatment group. There was a statistically significant difference in the occurrence of pressure injuries between the nontreatment group and the treatment group ( p = .033). The average Braden Q pressure injury score was 12.20 ± 2.280 at the beginning of the intensive care hospitalization, and 13.73 ± 3.312 at discharge in the treatment group ( p < .001). The results show that the risk of pressure injuries was reduced and pressure injuries occurred later when an evidence-based pressure injury prevention guide was used.

Efficacy of the Kampo Medicine Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in), a Traditional Herbal Medicine, in the Treatment of Maternity Blues Syndrome in the Postpartum Period

2005 ◽  
Vol 33 (01) ◽  
pp. 117-126 ◽  
Author(s):  
Takahisa Ushiroyama ◽  
Kou Sakuma ◽  
Minoru Ueki
Keyword(s):  
Herbal Medicine ◽  
Postpartum Period ◽  
Depressive Mood ◽  
Psychological State ◽  
Control Group ◽  
Clinical Effects ◽  
Traditional Herbal Medicine ◽  
College Hospital ◽  
Normal Delivery ◽  
Significant Difference

This study was to evaluate the clinical efficacy of Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in), a Japanese traditional herbal medicine, in stabilizing postpartum psychological state. We enrolled 268 women who had a normal delivery in Osaka Medical College Hospital or its affiliated clinics and randomly assigned them to the following two groups: a group of 134 women who received Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) at a dose of 6.0 g/day and another group of 134 women without Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) (control group). We observed 2.06-fold and 1.67-fold higher incidences of depressive mood and nervousness, respectively, after delivery in the control group than in the Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) group. Within 3 weeks of postpartum, there was a significant difference in the incidences of maternity blues between the Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) group (15.7%; 21/134) and the control group (32.1%; 43/134) (p=0.0195). No adverse effects were observed in this study. The results of this study demonstrate the beneficial clinical effects of Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) in stabilizing psychological state in the postpartum period. Xiong-gui-tiao-xue-yin (Kyuki-chouketsu-in) can be expected to improve the mental health of women in the postpartum period and prevent maternity blues.

scholarly journals Convalescent Plasma Treatment Reduced Mortality in Patients With Severe Pandemic Influenza A (H1N1) 2009 Virus Infection

2011 ◽  
Vol 52 (4) ◽  
pp. 447-456 ◽  
Author(s):  
Ivan FN Hung ◽  
Kelvin KW To ◽  
Cheuk-Kwong Lee ◽  
Kar-Lung Lee ◽  
Kenny Chan ◽  
...  
Keyword(s):  
Intensive Care ◽  
Viral Load ◽  
Treatment Group ◽  
Respiratory Tract ◽  
Plasma Treatment ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Control Group ◽  
Severity Scores ◽  
Influenza A H1n1

Background. Experience from treating patients with Spanish influenza and influenza A(H5N1) suggested that convalescent plasma therapy might be beneficial. However, its efficacy in patients with severe pandemic influenza A(H1N1) 2009 virus (H1N1 2009) infection remained unknown. Methods. During the period from 1 September 2009 through 30 June 2010, we conducted a prospective cohort study by recruiting patients aged ≥18 years with severe H1N1 2009 infection requiring intensive care. Patients were offered treatment with convalescent plasma with a neutralizing antibody titer of ≥1:160, harvested by apheresis from patients recovering from H1N1 2009 infection. Clinical outcome was compared with that of patients who declined plasma treatment as the untreated controls. Results. Ninety-three patients with severe H1N1 2009 infection requiring intensive care were recruited. Twenty patients (21.5%) received plasma treatment. The treatment and control groups were matched by age, sex, and disease severity scores. Mortality in the treatment group was significantly lower than in the nontreatment group (20.0% vs 54.8%; P =  .01). Multivariate analysis showed that plasma treatment reduced mortality (odds ratio [OR], .20; 95% confidence interval [CI], .06-.69; P =  .011), whereas complication of acute renal failure was independently associated with death (OR, 3.79; 95% CI, 1.15-12.4; P =  .028). Subgroup analysis of 44 patients with serial respiratory tract viral load and cytokine level demonstrated that plasma treatment was associated with significantly lower day 3, 5, and 7 viral load, compared with the control group (P &lt;  .05). The corresponding temporal levels of interleukin 6, interleukin 10, and tumor necrosis factor α (P &lt;  .05) were also lower in the treatment group. Conclusions. Treatment of severe H1N1 2009 infection with convalescent plasma reduced respiratory tract viral load, serum cytokine response, and mortality.

scholarly journals Implementation of Nurse-Led, Goal-Directed Lung Physiotherapy for Older Patients With Sepsis and Pneumonia in the ICU

2021 ◽  
Vol 8 ◽  
Author(s):  
Jianhua Sun ◽  
Na Cui ◽  
Wen Han ◽  
Qi Li ◽  
Hao Wang ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Treatment Group ◽  
Older Patients ◽  
Control Group ◽  
Icu Mortality ◽  
Two Phase ◽  
Before And After ◽  
Before And After Study

Objectives: This study aimed to investigate the effect of nurse-led, goal-directed lung physiotherapy (GDLPT) on the prognosis of older patients with sepsis caused by pneumonia in the intensive care unit.Methods: We conducted a prospective, two-phase (before-and-after) study over 3 years called the GDLPT study. All patients received standard lung therapy for sepsis caused by pneumonia and patients in phase 2 also received GDLPT. In this study, 253 older patients (age ≥ 65 years) with sepsis and pneumonia were retrospectively analyzed. The main outcome was 28 day mortality.Results: Among 742 patients with sepsis, 253 older patients with pneumonia were divided into the control group and the treatment group. Patients in the treatment group had a significantly shorter duration of mechanical ventilation [5 (4, 6) vs. 5 (4, 8) days; P = 0.045], and a lower risk of intensive care unit (ICU) mortality [14.5% (24/166) vs. 28.7% (25/87); P = 0.008] and 28 day mortality [15.1% (25/166) vs. 31% (27/87); P = 0.005] compared with those in the control group. GDLPT was an independent risk factor for 28 day mortality [odds ratio (OR), 0.379; 95% confidence interval (CI), 0.187–0.766; P = 0.007].Conclusions: Nurse-led GDLPT shortens the duration of mechanical ventilation, decreases ICU and 28-day mortality, and improves the prognosis of older patients with sepsis and pneumonia in the ICU.

scholarly journals Comparison between fractional Co2 laser-triamcinolone injection combination therapy and triamcinolone injection monotherapy for keloid

2019 ◽  
Author(s):  
M. Yulianto Listiawan ◽  
Dwi Murtiastutik ◽  
Willy Sandhika ◽  
Brama Rachmantyo ◽  
Putri Hendria Wardhani
Keyword(s):  
Treatment Group ◽  
Combination Therapy ◽  
Triamcinolone Acetonide ◽  
Co2 Laser ◽  
Laser Energy ◽  
Treatment Options ◽  
Control Group ◽  
Fractional Co2 Laser ◽  
Triamcinolone Injection ◽  
Collagen Density

The histopathologic view of keloid shows dense fibroblasts and bundles of collagen throughout dermis. Treatment that completely cure keloid still not exist, although there are many treatment options. The monotherapy fractional CO2 laser shows good results, but is still as an adjuvant therapy. Fractional CO2 laser affects fibroblast and its functions in producing collagen. The combination therapy will combine the selective phototermolysis effect of CO2 lasers with antimitotic and antiinflammatory effects of corticosteroids. This study was an open trial with parallel design that compared fractional CO2 laser-intralesional triamcinolone acetonide combination therapy (treatment group) and intralesional triamcinolone acetonide (control group) in keloid patients with collagen density as evaluation parameter. The dose of triamcinolone was 10 mg/ml of 0.05-0.1 ml/cm2 of keloid. Fractional CO2 laser energy setting was 10-20 mJ. The decrease of collagen density in control and treatment group was significant (p=0.008 and p=0.001), although the decrease difference between control and treatment group was not significant (p=0.328). The collagen density that decrease in a shorter time shows that fractional CO2 laser could be a good combination therapy.

scholarly journals Infliximab and Intravenous Gammaglobulin in Hospitalized Severe COVID-19 Patients in Intensive Care Unit

2021 ◽  
Vol 24 (2) ◽  
pp. 139-143
Author(s):  
Mohsen Farrokhpour ◽  
Nader Rezaie ◽  
Najmeh Moradi ◽  
Fatemeh Ghaffari Rad ◽  
Shirin Izadi ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Combination Therapy ◽  
Clinical Symptoms ◽  
Observational Research ◽  
Control Group ◽  
Therapeutic Effects ◽  
Significant Difference ◽  
Intravenous Gammaglobulin ◽  
Underlying Diseases

Background: Severe coronavirus disease 2019 (COVID-19) may lead to the cytokine storm syndrome which may cause acute respiratory failure syndrome and death. Our aim was to investigate the therapeutic effects of infliximab, intravenous gammaglobulin (IVIg) or combination therapy in patients with severe COVID-19 disease admitted to the intensive care unit (ICU). Methods: In this observational research, we studied 104 intubated adult patients with severe COVID-19 infection (based on clinical symptoms, and radiographic or CT scan parameters) who were admitted to the ICU of a multispecialty hospital during March 2020 in Tehran, Iran. All cases received standard treatment regimens as local protocol (Oseltamivir + hydroxychloroquine + lopinavir/ritonavir or sofosbuvir or atazanavir ± ribavirin). The cases were grouped as controls (n = 43), infliximab (n = 27), IVIg (n = 23) and combination (n = 11). Results: There was no significant difference between controls and treatment groups in terms of underlying diseases or the number of underlying diseases. The mean age (SD) of cases was 72.42 (16.06) in the control group, 64.52 (12.965) in IVIg, 63.40 (17.57) in infliximab and 64.00 (11.679) in combination therapy; (P = 0.047, 0.031 and 0.11, respectively). Also, 37% in the infliximab group, 26.1% in IVIg, 45.5% in combination therapy, and 62.8% in the control group expired (all P < 0.05). Hazard ratios were 0.31 in IVIg (95% CI: 0.12-0.76, P = 0.01), 0.30 in infliximab (95% CI: 0.13-0.67, P = 0.004), 0.39 in combination therapy (95% CI: 0.12-1.09, P = 0.071). Conclusion: According to the findings of this study, it seems that infliximab and IVIg, alone or together, in patients with severe COVID-19 disease can be considered an effective treatment.

Efficacy of quxie capsule in metastatic colorectal cancer: Update of a double-blind, randomized, placebo controlled trial.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e15030-e15030
Author(s):  
Tong Zhang ◽  
Wenting He ◽  
Yun Xu ◽  
Bin He ◽  
Yufei Yang
Keyword(s):  
Colorectal Cancer ◽  
Treatment Group ◽  
Herbal Medicine ◽  
Metastatic Colorectal Cancer ◽  
Chinese Herbal Medicine ◽  
Conventional Therapy ◽  
Controlled Trial ◽  
Control Group ◽  
Double Blind ◽  
Chinese Herbal

e15030 Background: To verify the efficacy of Quxie Capsule in patients with metastatic colorectal cancer (mCRC). Methods: This is a update of a randomized, double-blind, placebo-controlled trial. Between April 2014 and July 2015, 121 patients were enrolled in the study. Sixty patients were eligible and randomized to the two groups at a 1:1 ratio. Treatment group received conventional therapy and Chinese herbal medicine combined with Quxie Capsule for 3 months. Control group received conventional therapy and Chinese herbal medicine combined with placebo for 3 months. Main outcome measures were overall survival (OS) and progression-free survival (PFS). As of Dec 31st 2018, one patient in the control group was still alive, and all the other patients reached the main clinical endpoint. Median follow-up time was 19.4 months. Bo Ao Tong (Beijing) Medical Technology Co. Ltd. was responsible for the protocols of blind and block randomization. Results: The median OS were 23.9 months in the treatment group [95% confidence interval (CI) 15.9–28.5] vs. 14.3 months in the control group (95% CI 11.3–21.4) (Kaplan–Meier, Log-rank P=0.032), hazard ratio (95%CI)= 0.55 (0.31, 0.95), P=0.04. In the subgroups of left-sided colon, RAS wild type, non-targeted therapy, colon cancer and ≥second-line therapy, the median OS of the treatment group and the control group were respectively: 20.9 vs 12.2m, 17.4 vs 14.4m, 20.8 vs 12.0m, 25.1 vs 18.5m, 25.1 vs 12.0m ( P=0.037, 0.019, 0.022, 0.018, 0.007). There were no significant differences between the two groups in PFS. Conclusions: Quxie Capsule showed good efficacy, can reduce the risk of death and prolong the OS of patients with mCRC. Clinical trial information: ChiCTR-IOR-16009733.

scholarly journals Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data

BMJ ◽  
2020 ◽  
pp. m1844 ◽  
Author(s):  
Matthieu Mahévas ◽  
Viet-Thi Tran ◽  
Mathilde Roumier ◽  
Amélie Chabrol ◽  
Romain Paule ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Overall Survival ◽  
Acute Respiratory Distress Syndrome ◽  
Intensive Care ◽  
Treatment Group ◽  
Confidence Interval ◽  
Distress Syndrome ◽  
Routine Care ◽  
Hospital Treatment ◽  
Control Group

Abstract Objective To assess the effectiveness of hydroxychloroquine in patients admitted to hospital with coronavirus disease 2019 (covid-19) pneumonia who require oxygen. Design Comparative observational study using data collected from routine care. Setting Four French tertiary care centres providing care to patients with covid-19 pneumonia between 12 March and 31 March 2020. Participants 181 patients aged 18-80 years with documented severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia who required oxygen but not intensive care. Interventions Hydroxychloroquine at a dose of 600 mg/day within 48 hours of admission to hospital (treatment group) versus standard care without hydroxychloroquine (control group). Main outcome measures The primary outcome was survival without transfer to the intensive care unit at day 21. Secondary outcomes were overall survival, survival without acute respiratory distress syndrome, weaning from oxygen, and discharge from hospital to home or rehabilitation (all at day 21). Analyses were adjusted for confounding factors by inverse probability of treatment weighting. Results In the main analysis, 84 patients who received hydroxychloroquine within 48 hours of admission to hospital (treatment group) were compared with 89 patients who did not receive hydroxychloroquine (control group). Eight additional patients received hydroxychloroquine more than 48 hours after admission. In the weighted analyses, the survival rate without transfer to the intensive care unit at day 21 was 76% in the treatment group and 75% in the control group (weighted hazard ratio 0.9, 95% confidence interval 0.4 to 2.1). Overall survival at day 21 was 89% in the treatment group and 91% in the control group (1.2, 0.4 to 3.3). Survival without acute respiratory distress syndrome at day 21 was 69% in the treatment group compared with 74% in the control group (1.3, 0.7 to 2.6). At day 21, 82% of patients in the treatment group had been weaned from oxygen compared with 76% in the control group (weighted risk ratio 1.1, 95% confidence interval 0.9 to 1.3). Eight patients in the treatment group (10%) experienced electrocardiographic modifications that required discontinuation of treatment. Conclusions Hydroxychloroquine has received worldwide attention as a potential treatment for covid-19 because of positive results from small studies. However, the results of this study do not support its use in patients admitted to hospital with covid-19 who require oxygen.

scholarly journals Phytopreparations in complex treatment of patients with benign prostatic hyperplasia and erectile dysfunction

2018 ◽  
Vol 19 (4) ◽  
pp. 46-53
Author(s):  
A. B. Bat’ko
Keyword(s):  
Erectile Dysfunction ◽  
Benign Prostatic Hyperplasia ◽  
Treatment Group ◽  
Combination Therapy ◽  
Family Doctor ◽  
Prostatic Hyperplasia ◽  
Control Group ◽  
Symptomatic Therapy ◽  
Phosphodiesterase Type 5 Inhibitors ◽  
Study Objective

The study objectiveis to evaluate clinical effectiveness of a phytopharmaceutical Vialissil® for treatment of patients with benign prostatic hyperplasia (BPH) and erectile dysfunction.Materials and methods. At the multi-specialty clinic “Family Doctor” (Saint Petersburg) 34 patients aged from 55 to 67 years (mean age 59.6 + 0.7 years) with BPH and concomitant erectile dysfunction without the need for surgical intervention were examined. All patients received previously prescribed symptomatic therapy for BPH and erectile dysfunction (a-adrenoblockers and phosphodiesterase type 5 inhibitors on demand). The treatment group included 18 patients who additionally received Vialissil® as capsules once a day for 30 days. The remaining 16 patients were the control group.Results.After treatment, intensity of general symptoms decreased more in the treatment group than in the control group (by 10 and 4 points, respectively). After the course of therapy, erectile function improved in both groups but only in the treatment group these dynamics were statistically significant. An increase in testosterone level was statistically significant only after combination therapy with Vialissil® (by 16.5 %), and blood level of biologically accessible (active) testosterone increased twofold.Conclusion.Combination therapy for BPH and erectile dysfunction including administration of the Vialissil® phytopharmaceutical more effectively decreases disease intensity compared to standard therapy.

scholarly journals EFEKTIVITAS PENDIDIKAN KESEHATAN DENGAN MEDIA KIPAS EDUKASI TERHADAP IMPLEMENTASI BUDAYA NIFAS

2021 ◽  
Vol 7 (3) ◽  
pp. 383-390
Author(s):  
Sinta Nuryati ◽  
Fuadah Ashri Nurfurqoni
Keyword(s):  
Herbal Medicine ◽  
Health Education ◽  
Postpartum Period ◽  
Total Sample ◽  
Postpartum Care ◽  
Personal Hygiene ◽  
Control Group ◽  
P Value ◽  
Research Subjects ◽  
Traditional Herbal Medicine

Background: Most regions in Indonesia have a culture in the form of taboos or recommendations that mothers must do during the postpartum period. Some cultures applied during the puerperium have no logical basis, especially from a medical point of view. The implementation of an illogical or harmful postpartum culture can harm both mother and child. Thus, there is a need for health education that can prevent the implementation of negative postpartum culture. Midwives need to have the right health education strategy with simple, easy-to-remember, and understand media. One of the strategies is health education using Education Fan Media. This fan-shaped media is a visual media that is more attractive, easy to remember, and easy to read anywhere.Purpose: this study was to determine the effectiveness of health education with educational fan media on the implementation of postpartum culture in Bogor Regency.Methods: This study uses a Quasi-Experimental design, using a Non-randomized approach with Control Posttest only Design. The research subjects were early postpartum mothers (0-7 days postpartum) with a total sample of 25 people in each intervention and control group who met the inclusion and exclusion criteria—the research held in the Kemang District, Bogor Regency, July to October 2019. The research instrument used was a questionnaire. The intervention provided was health education with a fan for postpartum education to the closest family, including husband, mother, in-laws, or grandmother who lived at home. This educational fan contains about postpartum care and negative culture during the postpartum period. The independent variable in this study is Health Education with educational fan media. The dependent variable is culture during the puerperium with sub-variables of abstinence, traditional herbal medicine, personal hygiene, and postpartum care.Results: The results of data analysis using unpaired t-test showed that health education with educational fan media had a significant effect on implementing personal hygiene culture and postpartum care with p <0.005. Health education with educational fan media has no significant effect on the implementation of dietary restrictions and traditional herbal medicine with a p-value > 0.005Conclusion: Health education with Education Fan Media has a significant effect on implementing personal hygiene culture and postpartum care in Bogor Regency. Suggestion Health education using educational fans for postpartum more effective if carried out more than once. This health education should repeat during the postpartum home visit. Keywords: Health education, education fan, postpartum culture ABSTRAK Latar Belakang: Sebagian besar daerah di Indonesia memiliki budaya berupa pantangan ataupun anjuran tertentu yang harus dilakukan ibu pada masa nifas. Beberapa budaya yang diterapkan pada masa nifas tidak memiliki dasar logis, terutama dari segi medis.  Praktik penerapan budaya nifas yang tidak logis  atau negatif dapat membahayakan ibu dan anak. Dengan demikian perlu adanya pendidikan kesehatan yang dapat mencegah praktik penerapan budaya nifas yang negatif.  Sebagai Bidan perlu memiliki strategi pendidikan kesehatan yang tepat dengan media yang sederhana, mudah diingat dan difahami. Salah satu strateginya adalah pendidikan kesehatan dengan menggunakan Media Kipas Edukasi. Media berbentuk kipas ini merupakan media visual uang diharapkan lebih menarik, mudah di ingat dan mudah dibaca dimana sajaTujuan: dalam penelitian ini adalah untuk mengetahui Efektivitas Pendidikan Kesehatan dengan Media Kipas Edukasi Terhadap Implementasi Budaya Nifas di Kabupaten Bogor.Metode: Penelitian ini menggunakan desain Quasi Eksperiment, dengan menggunakan pendekatan  Non-randomized with  Control Postest only Design. Subjek Penelitian adalah ibu nifas dini (0-7 hari postpartum) dengan jumlah sampel 25 orang pada setiap kelompok intervensi dan kontrol yang memenuhi kriteria inklusi dan eksklusi. Penelitian dilakukan  di wilayah Kecamatan Kemang, Kabupaten Bogor pada bulan Juli sampai Oktober 2019. Instrument penelitian yang digunakan adalah kuesioner. Intervensi yang diberikan yaitu pendidikan kesehatan dengan Kipas edukasi nifas  kepada keluarga terdekat diantaranya suami, ibu,mertua atau nenek yang tinggal serumah. Kipas edukasi  ini berisi mengenai perawatan masa nifas dan budaya negatif selama masa nifas. Variabel independent dalam penelitian ini yaitu Pendidikan Kesehatan dengan media kipas edukasi, sedangkan variabel dependent yaitu Budaya pada masa nifas dengan sub variabel budaya pantangan makan, jamu tradisional, dan kebersihan diri, serta perawatan nifasHasil: Hasil analisis data  dengan menggunakan menggunakan uji t tidak berpasangan didapatkan hasil bahwa, pendidikan kesehatan dengan media kipas edukasi berpengaruh secara signifikan terhadap implementasi  budaya kebersihan diri dan perawatan masa nifas dengan nilai p <0.005.  Pendidikan kesehatan dengan media kipas edukasi tidak  berpengaruh secara signifikan terhadap implementasi  budaya pantangan makan dan   jamu tradisonal dengan nilai p > 0.005Kesimpulan: pendidikan kesehatan dengan Media Kipas Edukasi berpengaruh secara signifikan terhadap implementasi  budaya kebersihan diri dan perawatan masa nifas di Kabupaten Bogor.Saran supaya lebih efektif, pendidikan kesehatan dengan menggunakan  kipas edukasi terhadap ibu nifas, sebaiknya  dilakukan lebih dari satu kali. Pendidikan kesehatan ini  dapat diulangi pada saat kunjungan rumah ibu nifas Kata kunci: Pendidikan kesehatan, kipas edukasi, Budaya nifas

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