PHOTOTHERAPY FOR MILD TO MODERATE ACNE VULGARIS WITH PORTABLE BLUE AND RED LED

In this paper, we studied portable blue and red light-emitting-diode (LED) light sources in phototherapy for mild to moderate acne vulgaris to evaluate the efficacy and tolerance of patients. Patients, randomly divided into blue and red groups, received either blue or red LED phototherapy twice a week for four weeks. After complete treatment, the number of lesions reduced by 71.4% in the blue group, in contrast to 19.5% in the red group. No obvious side effects were observed during and one month after the treatment, except for some mild dryness mentioned by several patients.

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Effectiveness of light emitting diode versus conventional phototherapy in neonatal hyperbilirubinemia: a hospital based observational study

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20200780 ◽

2020 ◽

Vol 8 (3) ◽

pp. 1051

Author(s):

Radheshyam Purkait ◽

Manik Mondal

Keyword(s):

Side Effects ◽

Light Emitting Diode ◽

Total Duration ◽

Conventional Group ◽

Light Sources ◽

Fluorescent Lamp ◽

Light Emitting ◽

Led Phototherapy ◽

Significant Difference ◽

Compact Fluorescent Lamp

Background: The most commonly used light sources in the conventional phototherapy units are compact fluorescent lamp (CFL), halogen spotlights and fiberoptic blankets. Recently light emitting diodes (LED) has emerged as better light source for phototherapy and almost replacing all the available conventional light sources. Comparative studies on the efficacy of LED versus conventional phototherapy are limited from India. That is why; this study was undertaken.Methods: 48 neonates of ≥35 weeks gestational age with hyperbilirubinemia were participated in this study. Among them, 24 neonates received conventional phototherapy and rest of them received LED phototherapy. The rate of fall of bilirubin levels at 6 hours and at completion along with total duration of phototherapy in both groups was measured. Results analysed by standard statistical methods.Results: LED phototherapy units showed higher rate of fall in bilirubin at six hrs (LED group: 0.38±0.05 mg/dl/hr versus conventional group: 0.30±0.04 mg/dl/hr, p<0.05) and after completion of therapy (LED group: 0.32±0.03 mg/dl/hr versus conventional group: 0.26±0.03 mg/dl/hr, p<0.05) compared to conventional group. Significant difference was documented in total duration of phototherapy in LED group (30.8±1.8 hours) when compared to conventional group (34.6±0.7 hours). None of the neonate showed phototherapy failure. Side effects were minimal and comparable in both the groups.Conclusions: The LED phototherapy units are more efficacious in terms of higher rate of fall of bilirubin levels and lesser duration of phototherapy compared to conventional phototherapy units.

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Growth and Appearance Quality of Four Microgreen Species under Light-emitting Diode Lights with Different Spectral Combinations

HortScience ◽

10.21273/hortsci14925-20 ◽

2020 ◽

Vol 55 (9) ◽

pp. 1399-1405

Author(s):

Qinglu Ying ◽

Yun Kong ◽

Youbin Zheng

Keyword(s):

Plant Height ◽

High Intensity ◽

Light Emitting Diode ◽

Red Light ◽

Photon Flux ◽

Photon Flux Density ◽

Light Emitting ◽

Led Light ◽

Red Led ◽

Dry Biomass

To investigate plant growth and quality responses to different light spectral combinations, cabbage (Brassica oleracea L. var. capitata f. rubra), kale (Brassica napus L. ‘Red Russian’), arugula (Eruca sativa L.), and mustard (Brassica juncea L. ‘Ruby steak’) microgreens were grown in a controlled environment using sole-source light with six different spectra: 1) FL: cool white fluorescent light; 2) BR: 15% blue and 85% red light-emitting diode (LED); 3) BRFRL: 15% blue, 85% red, and 15.5 µmol·m−2·s−1 far-red (FR) LED; 4) BRFRH: 15% blue, 85% red, and 155 µmol·m−2·s−1 FR LED; 5) BGLR: 9% blue, 6% green, and 85% red LED; and 6) BGHR: 5% blue, 10% green, and 85% red LED. For all the light treatments, the total photosynthetic photon flux density (PPFD) was set at ≈330 µmol·m−2·s−1 under a 17-hour photoperiod, and the air temperature was ≈21 °C with 73% relative humidity (RH). At harvest, BR vs. FL increased plant height for all the tested species except arugula, and enlarged cotyledon area for kale and arugula. Adding high-intensity FR light to blue and red light (i.e., BRFRH) further increased plant height for all species, and cotyledon area for mustard, but it did not affect the fresh or dry biomass for any species. Also, BRFRH vs. BR increased cotyledon greenness for green-leafed species (i.e., arugula, cabbage, and kale), and reduced cotyledon redness for red-leafed mustard. However, BGLR, BGHR, and BRFRL, compared with BR, did not affect plant height, cotyledon area, or fresh or dry biomass. These results suggest that the combination of 15% blue and 85% red LED light can potentially replace FL as the sole light source for indoor production of the tested microgreen species. Combining high-intensity FR light, rather than low-level (≤10%) green light, with blue and red light could be taken into consideration for the optimization of LED light spectral quality in microgreen production under environmental conditions similar to this experiment.

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Effects of Light-Emitting Diodes on the Accumulation of Glucosinolates and Phenolic Compounds in Sprouting Canola (Brassica napus L.)

Foods ◽

10.3390/foods8020076 ◽

2019 ◽

Vol 8 (2) ◽

pp. 76 ◽

Cited By ~ 7

Author(s):

Chang Park ◽

Nam Kim ◽

Jong Park ◽

Sook Lee ◽

Jong-Won Lee ◽

...

Keyword(s):

Brassica Napus ◽

Phenolic Compounds ◽

Light Emitting Diode ◽

Red Light ◽

Dry Weight ◽

Total Phenolic ◽

Brassica Napus L ◽

Light Emitting ◽

Led Light ◽

Sprout Growth

In this study, we investigated optimal light conditions for enhancement of the growth and accumulation of glucosinolates and phenolics in the sprouts of canola (Brassica napus L.). We found that the shoot lengths and fresh weights of red light-irradiated sprouts were higher than those of sprouts exposed to white, blue, and blue + red light, whereas root length was not notably different among red, blue, white, and blue + red light treatments. The accumulations of total glucosinolates in plants irradiated with white, blue, and red lights were not significantly different (19.32 ± 0.13, 20.69 ± 0.05, and 20.65 ± 1.70 mg/g dry weight (wt.), respectively). However, sprouts exposed to blue + red light contained the lowest levels of total glucosinolates (17.08 ± 0.28 mg/g dry wt.). The accumulation of total phenolic compounds was the highest in plants irradiated with blue light (3.81 ± 0.08 mg/g dry wt.), 1.33 times higher than the lowest level in plants irradiated with red light (2.87 ± 0.05 mg/g dry wt.). These results demonstrate that red light-emitting diode (LED) light is suitable for sprout growth and that blue LED light is effective in increasing the accumulation of glucosinolates and phenolics in B. napus sprouts.

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Effect of 660 nm Light-Emitting Diode on the Wound Healing in Fibroblast-Like Cell Lines

International Journal of Photoenergy ◽

10.1155/2015/916838 ◽

2015 ◽

Vol 2015 ◽

pp. 1-9 ◽

Cited By ~ 1

Author(s):

Myung-Sun Kim ◽

Yong-Ick Cho ◽

Min-Suk Kook ◽

Sang-Chul Jung ◽

Young-Hyun Hwang ◽

...

Keyword(s):

Cell Proliferation ◽

Wound Healing ◽

Near Infrared ◽

Light Emitting Diode ◽

Biological Effects ◽

Soft Tissue Injuries ◽

Light Emitting ◽

Led Light ◽

Red Led ◽

And Migration

Light in the red to near-infrared (NIR) range (630–1000 nm), which is generated using low energy laser or light-emitting diode (LED) arrays, was reported to have a range of beneficial biological effects in many injury models. NIR via a LED is a well-accepted therapeutic tool for the treatment of infected, ischemic, and hypoxic wounds as well as other soft tissue injuries in humans and animals. This study examined the effects of exposure to 660 nm red LED light at intensities of 2.5, 5.5, and 8.5 mW/cm2for 5, 10, and 20 min on wound healing and proliferation in fibroblast-like cells, such as L929 mouse fibroblasts and human gingival fibroblasts (HGF-1). A photo illumination-cell culture system was designed to evaluate the cell proliferation and wound healing of fibroblast-like cells exposed to 600 nm LED light. The cell proliferation was evaluated by MTT assay, and a scratched wound assay was performed to assess the rate of migrating cells and the healing effect. Exposure to the 660 nm red LED resulted in an increase in cell proliferation and migration compared to the control, indicating its potential use as a phototherapeutic agent.

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Toluidine blue O and porphyrin-mediated photodynamic therapy on three main pathogenic bacteria of periodontitis using portable LED phototherapy device

Journal of Innovative Optical Health Sciences ◽

10.1142/s1793545815500170 ◽

2015 ◽

Vol 08 (04) ◽

pp. 1550017 ◽

Cited By ~ 3

Author(s):

Xuewei Jiang ◽

Zhichao Fan ◽

Yili Yu ◽

Chenying Shao ◽

Yuanzhen Suo ◽

...

Keyword(s):

Photodynamic Therapy ◽

Toluidine Blue ◽

Pathogenic Bacteria ◽

Light Emitting Diode ◽

Red Light ◽

In Vitro Screening ◽

Light Emitting ◽

Led Phototherapy ◽

Prevotella Melaninogenica

Photodynamic therapy (PDT) has been commonly used in treating many diseases, such as cancer and infectious diseases. We investigated the different effects of PDT on three main pathogenic bacteria of periodontitis — Prevotella melaninogenica (P.m.), Porphyromonas gingivalis (P.g.) and Aggregatibacter actinomycetemcomitans (A.a.). The portable red light-emitting diode (LED) phototherapy device was used to assess the exogenous PDT effects with different light doses and photosensitizer concentrations (Toluidine blue O, TBO). The portable blue LED phototherapy device was used to assess the endogenous PDT effects with the use of endogenous photosensitizers (porphyrin) under different light doses. We found out that both exogenous and endogenous PDT were able to restrict the growth of all the three bacteria significantly. Moreover, the optimal PDT conditions for these bacteria were obtained through this in vitro screening and could guide the clinical PDT on periodontitis.

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Morphogenetic and physiological effects of LED spectra on the apical buds of Ficus carica var. Black Jack

Scientific Reports ◽

10.1038/s41598-021-03056-7 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Ankita Rajendra Parab ◽

Kho Ying Han ◽

Bee Lynn Chew ◽

Sreeramanan Subramaniam

Keyword(s):

Callus Formation ◽

Light Emitting Diode ◽

Multiple Shoots ◽

Cellular Level ◽

Ficus Carica ◽

Light Sources ◽

Light Emitting ◽

Apical Buds ◽

Red Led

AbstractThe use of artificial light sources such as light-emitting diodes (LEDs) has become a prerequisite in tissue culture studies to obtain morphogenetic enhancements on in vitro plants. This technology is essential for developmental enhancements in the growing plant cultures due to its light quality and intensity greatly influencing the in vitro growing explants at a cellular level. The current study investigates the effects of different light-emitting diode (LED) spectra on the growth of apical buds of Ficus carica var. Black Jack. Ficus carica, commonly known as figs is rich in vitamins, minerals, and phytochemicals capable of treating microbial infections and gastric, inflammatory, and cardiac disorders. Apical buds of Ficus carica var. Black Jack, presented morphogenetic changes when grown under six different LED spectra. The highest multiple shoots (1.80 per growing explant) and healthy growing cultures were observed under the blue + red LED spectrum. Wound-induced callus formation was observed on apical buds grown under green LED spectrum and discolouration of the growing shoots were observed on the cultures grown under far-red LED spectrum. Multiple shoots obtained from the blue + red LED treatment were rooted using 8 µM indole-3-acetic acid (IAA), and the rooted plantlets were successfully acclimatised. Compared with the other monochromatic LEDs, blue + red proved to be significantly better for producing excellent plant morphogeny. It is apparent that blue and red LED is the most suitable spectra for the healthy development of plants. The findings have confirmed that the combination of blue + red LED can potentially be used for enhancing growth yields of medicinally and commercially important plants.

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The effects of light-emitting diode lighting on greenhouse plant growth and quality

Agricultural and Food Science ◽

10.23986/afsci.7897 ◽

2013 ◽

Vol 22 (2) ◽

pp. 223-234 ◽

Cited By ~ 193

Author(s):

Margit Olle ◽

Akvile Viršile

Keyword(s):

Growth Promotion ◽

Light Emitting Diode ◽

Red Light ◽

Growth Yield ◽

Sweet Pepper ◽

Light Sources ◽

Light Emitting ◽

Sodium Lamp ◽

Greenhouse Plant ◽

High Pressure Sodium Lamp

The aim of this study is to present the light emitting diode (LED) technology for greenhouse plant lighting and to give an overview about LED light effects on photosynthetic indices, growth, yield and nutritional value in green vegetables and tomato, cucumber, sweet pepper transplants. The sole LED lighting, applied in closed growth chambers, as well as combinations of LED wavelengths with conventional light sources, fluorescent and high pressure sodium lamp light, and natural illumination in greenhouses are overviewed. Red and blue light are basal in the lighting spectra for green vegetables and tomato, cucumber, and pepper transplants; far red light, important for photomorphogenetic processes in plants also results in growth promotion. However, theoretically unprofitable spectral parts as green or yellow also have significant physiological effects on investigated plants. Presented results disclose the variability of light spectral effects on different plant species and different physiological indices.

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The Effects of Eggplants Illuminated by Red LED (Light Emitting Diode) on the Population Density of the Melon Thrips, Thrips palmi (Thysanoptera: Thripidae)

Japanese Journal of Applied Entomology and Zoology ◽

10.1303/jjaez.2015.7 ◽

2015 ◽

Vol 59 (1) ◽

pp. 7-9 ◽

Cited By ~ 2

Author(s):

Manabu Shibao ◽

Hiroshi Tanaka

Keyword(s):

Population Density ◽

Light Emitting Diode ◽

Light Emitting ◽

Led Light ◽

Red Led ◽

Melon Thrips

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A Practical Method to Design Reflector-Based Light-Emitting Diode Luminaire for General Lighting

Advances in OptoElectronics ◽

10.1155/2018/7138592 ◽

2018 ◽

Vol 2018 ◽

pp. 1-10

Author(s):

Jinren Yan

Keyword(s):

Light Emitting Diode ◽

Spherical Surface ◽

Target Surface ◽

Practical Method ◽

Optical Simulation ◽

Light Sources ◽

Aspheric Surface ◽

Light Emitting ◽

Led Light ◽

Spherical Reflector

A reflector-based light-emitting diode (LED) luminaire structure that can achieve a large cut-off angle for general lighting is presented in this work. The proposed lighting unit mainly consists of a spherical reflector and a primary packaging lens that contains an aspheric surface and a spherical surface. The light rays emitted from the LED light source are well controlled by the spherical reflector and the aspheric surface of the lens for the purpose of obtaining a uniform illumination on the target surface. Both the ideal Lambertian LED and non-Lambertian LED light sources were employed to validate the proposed structure and the performance of the designed lighting units was analyzed by optical simulation. The results show that the light utilization efficiencies and the estimated uniformities are 92.96% and 91.11% for ideal Lambertian LED-based lighting unit and 93.31% and 91.64% for non-Lambertian LED-based lighting unit, respectively. Further analysis shows that the tolerances of horizontal, vertical, and rotational deviation of the both lighting units were about 2.0 mm, 1.0 mm, and 1.0°, respectively.

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