scholarly journals Extended Durability of a Cloth-Covered Star-Edwards Caged Ball Prosthesis in Aortic Position

2009 ◽  
Vol 2009 ◽  
pp. 1-2
Author(s):  
Yusuf Ata ◽  
Tamer Turk ◽  
Cüneyt Eris ◽  
Mihriban Yalcin ◽  
Filiz Ata ◽  
...  

The Starr-Edwards caged ball valve is one of the oldest cardiac valve prosthesis and was widely used all around the world in the past decades. Despite the long-term results that have been reported there are only a few cases reported that exceed 30 years of durability. Here in, we report a 53-year-old patient with a well-functioning 35-year-old aortic Starr-Edwards caged ball prosthesis.

1984 ◽  
Vol 37 (4) ◽  
pp. 328-336 ◽  
Author(s):  
C.G. Montero ◽  
J.J. Rufilanchas ◽  
A. Juffe ◽  
R. Burgos ◽  
J. Ugarte ◽  
...  

Viruses ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 569
Author(s):  
Jean-Nicolas Tournier ◽  
Joseph Kononchik

The eradication of infectious diseases has been achieved only once in history, in 1980, with smallpox. Since 1988, significant effort has been made to eliminate poliomyelitis viruses, but eradication is still just out of reach. As the goal of viral disease eradication approaches, the ability to recreate historically eradicated viruses using synthetic biology has the potential to jeopardize the long-term sustainability of eradication. However, the emergence of the severe acute respiratory syndrome-coronavirus (SARS-CoV)-2 pandemic has highlighted our ability to swiftly and resolutely respond to a potential outbreak. This virus has been synthetized faster than any other in the past and is resulting in vaccines before most attenuated candidates reach clinical trials. Here, synthetic biology has the opportunity to demonstrate its truest potential to the public and solidify a footing in the world of vaccines.


2014 ◽  
Vol 2 (4) ◽  
pp. 20-31
Author(s):  
Irina Yurievna Klychkova ◽  
Yuri Alexeevich Lapkin ◽  
Mikhail Pavlovich Konyukhov ◽  
Yulia Aleksandrovna Stepanova ◽  
Vladimir Markovich Kenis

Conservative treatment of congenital clubfoot is generally accepted standard in the world orthopedic practice. There are many techniques that basically include functional methods and techniques of passive correction of the deformity. We analyzed 10 years of experience in the treatment of primary clubfoot according to three techniques - Zatsepin’s method, author’s method and Ponseti method. The evaluation of treatment results in the short and long terms was carried out. Analysis of long-term results showed a statistically significant advantage of Pontseti method over the other used techniques.


Aorta ◽  
2021 ◽  
Author(s):  
Igor Vendramin ◽  
Uberto Bortolotti ◽  
Davide Nunzio De Manna ◽  
Andrea Lechiancole ◽  
Sandro Sponga ◽  
...  

AbstractSimultaneous replacement of the ascending aorta and aortic valve has always been a challenging procedure. Introduction of composite conduits, through various ingenious procedures and their modifications, has changed the outlook of patients with aortic valve disease and ascending aorta pathology. In the past 70 years, progress of surgical techniques and prosthetic materials has allowed such patients to undergo radical procedures providing excellent early and long-term results in both young and elderly patients. This article aims to review the most important technical advances in the treatment of aortic valve disease and ascending aorta aneurysms recognizing the important contributions in this field.


2021 ◽  
Vol 13 (16) ◽  
pp. 3264 ◽  
Author(s):  
Shuang Li ◽  
Zhongqiu Sun ◽  
Yafei Wang ◽  
Yuxia Wang

Studying urban expansion from a longer-term perspective is of great significance to obtain an in-depth understanding of the process of urbanization. Remote sensing data are mostly selected to investigate the long-term expansion of cities. In this study, we selected the world-class urban agglomeration of Beijing-Tianjin-Hebei (BTH) as the study area, and then discussed how to make full use of multi-source, multi-category, and multi-temporal spatial data (old maps and remote sensing images) to study long-term urbanization. Through this study, we addressed three questions: (1) How much has the urban area in BTH expanded in the past 100 years? (2) How did the urban area expand in the past century? (3) What factors or important historical events have changed the development of cities with different functions? By comprehensively using urban spatial data, such as old maps and remote sensing images, geo-referencing them, and extracting built-up area information, a long-term series of urban built-up areas in the BTH region can be obtained. Results show the following: (1) There was clear evidence of dramatic urban expansion in this area, and the total built-up area had increased by 55.585 times, from 126.181 km2 to 7013.832 km2. (2) Continuous outward expansion has always been the main trend, while the compactness of the built-up land within the city is constantly decreasing and the complexity of the city boundary is increasing. (3) Cities in BTH were mostly formed through the construction of city walls during the Ming and Qing dynasties, and the expansion process was mostly highly related to important political events, traffic development, and other factors. In summary, the BTH area, similarly to China and most regions of the world, has experienced rapid urbanization and the history of such ancient cities should be further preserved with the combined use of old maps.


2020 ◽  
Vol 8 (2) ◽  
pp. e000948 ◽  
Author(s):  
Olivier Michielin ◽  
Michael B Atkins ◽  
Henry B Koon ◽  
Reinhard Dummer ◽  
Paolo Antonio Ascierto

Melanoma treatment has been revolutionized over the past decade. Long-term results with immuno-oncology (I-O) agents and targeted therapies are providing evidence of durable survival for a substantial number of patients. These results have prompted consideration of how best to define long-term benefit and cure. Now more than ever, oncologists should be aware of the long-term outcomes demonstrated with these newer agents and their relevance to treatment decision-making. As the first tumor type for which I-O agents were approved, melanoma has served as a model for other diseases. Accordingly, discussions regarding the value and impact of long-term survival data in patients with melanoma may be relevant in the future to other tumor types. Current findings indicate that, depending on the treatment, over 50% of patients with melanoma may gain durable survival benefit. The best survival outcomes are generally observed in patients with favorable prognostic factors, particularly normal baseline lactate dehydrogenase and/or a low volume of disease. Survival curves from melanoma clinical studies show a plateau at 3 to 4 years, suggesting that patients who are alive at the 3-year landmark (especially in cases in which treatment had been stopped) will likely experience prolonged cancer remission. Quality-of-life and mixture-cure modeling data, as well as metrics such as treatment-free survival, are helping to define the value of this long-term survival. In this review, we describe the current treatment landscape for melanoma and discuss the long-term survival data with immunotherapies and targeted therapies, discussing how to best evaluate the value of long-term survival. We propose that some patients might be considered functionally cured if they have responded to treatment and remained treatment-free for at least 2 years without disease progression. Finally, we consider that, while there have been major advances in the treatment of melanoma in the past decade, there remains a need to improve outcomes for the patients with melanoma who do not experience durable survival.


2012 ◽  
Vol 62 (4) ◽  
pp. 423-434
Author(s):  
Jan Winiecki

A look at the Western debate about West’s problems reveals what the present writer regards in a large measure as an irritating superficiality. Nowhere is it better visible than in the mainstream discussions about the euro zone and its problems, where most debaters glide over the fundamentals of Europe’s long-term problems and concentrate on the superficial and short-term issues. The discussions on how to “save” the euro zone strangely forget the defects in its creation, glide over the lessons to be drawn from policies pursued during the past decade, and defend the virtue of maintaining its present membership. But the problems of Europe run much deeper than the survival or collapse of the monetary union. Even if we assume that the problems of confidence the member states have in each other’s behaviour are restored and the rest of the world regains confidence in the institutions of the monetary union, the fundamental problems will remain unsolved. A clue to the real long-term problems may be found in the answer to a rather simple question. It runs as follows: “Why is the large majority of European countries indebted to such an extent that any further increase in debt to GDP ratio generates panic reactions among potential lenders?”


1998 ◽  
Vol 37 (4II) ◽  
pp. 1053-1070 ◽  
Author(s):  
Sohail Jehangir Malik ◽  
Hina Nazli

By highlighting the lack of rigorous evidence and calling for a greater understanding of the interaction of the two processes, a recent study [Nelson et al. (1997)] has called into question the strong perception that poverty is both a consequence as well as a cause of resource degradation.1 This perception which is widely held is strongly evident in the writings of the multilateral development agencies such as the World Bank (1990) and IFAD (1992) and exists despite extensive reviews which indicate that the short- and long-term implications of land degradation are not very clear [see Scherr and Yadav (1995)]. Similarly, while knowledge about poverty is expanding rapidly, thanks in large parts to the massive international focus and resources brought to bear on its understanding in the past ten.........................


Author(s):  
Robert Pool

The past couple of decades have been a confusing, frustrating period for engineers. With their creations making the world an ever richer, healthier, more comfortable place, it should have been a time of triumph and congratulation for them. Instead, it has been an era of discontent. Even as people have come to rely on technology more and more, they have liked it less. They distrust the machines that are supposedly their servants. Sometimes they fear them. And they worry about the sort of world they are leaving to their children. Engineers, too, have begun to wonder if something is wrong. It is not simply that the public doesn’t love them. They can live with that. But some of the long-term costs of technology have been higher than anyone expected: air and water pollution, hazardous wastes, the threat to the Earth’s ozone layer, the possibility of global warming. And the drumbeat of sudden technological disaster over the past twenty years is enough to give anyone pause: Three Mile Island, Bhopal, the Challenger, Chernobyl, the Exxon Valdez, the downing of a commercial airliner by a missile from the U.S.S. Vincennes. Is it time to rethink our approach to technology? Some engineers believe that it is. In one specialty after another, a few prophets have emerged who argue for doing things in a fundamentally new way. And surprisingly, although these visionaries have focused on problems and concerns unique to their own particular areas of engineering, a single underlying theme appears in their messages again and again: Engineers should pay more attention to the larger world in which their devices will function, and they should consciously take that world into account in their designs. Although this may sound like a simple, even a self-evident, bit of advice, it is actually quite a revolutionary one for engineering. Traditionally, engineers have aimed at perfecting their machines as machines. This can be seen in the traditional measures of machines: how fast they are, how much they can produce, the quality of their output, how easy they are to use, how much they cost, how long they last.


1937 ◽  
Vol 33 (10) ◽  
pp. 1287-1287
Author(s):  
B. Ivanov

Author reports on the long-term results of X-ray therapy for hyperthyroidism, carried out over the past year in 140 cases. It turned out that the best results are observed with Graves' disease.


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