scholarly journals Cardiovascular Disease and Psychiatric Comorbidity: The Potential Role of Perseverative Cognition

2009 ◽  
Vol 2009 ◽  
pp. 1-8 ◽  
Author(s):  
Britta A. Larsen ◽  
Nicholas J. S. Christenfeld
Keyword(s):  
Cardiovascular Disease ◽  
Psychiatric Disorders ◽  
Potential Role ◽  
Cardiovascular Health ◽  
Acute Stress ◽  
Stressful Events ◽  
Disease Etiology ◽  
Perseverative Cognition ◽  
Cardiovascular Damage

The high comorbidity between psychiatric disorders and cardiovascular disease has received increasing attention, yet little is known about the processes linking the two. One plausible contributing mechanism is the tendency of those with psychiatric disorders to ruminate on stressful events. This phenomenon, sometimes called perseverative cognition, can extend the psychological and physiological effects of stress, which could contribute to cardiovascular disease etiology. In this paper, we discuss the potential role of perseverative cognition in mediating the relationship between psychiatric illness and cardiovascular disease. Rumination can delay physiological recovery from acute stress, which in turn has been found to predict future cardiovascular health. This delayed recovery could act as a mechanism in the longitudinal link between worry and cardiovascular health. The cognitive inflexibility that characterizes mood and anxiety disorders may then contribute to disease not by producing greater reactivity, but instead through extending activation, increasing the risks for cardiovascular damage.

Excess all-cause mortality during COVID-19 outbreak: potential role of untreated cardiovascular disease

2020 ◽  
Author(s):  
Andrea SAGLIETTO ◽  
Fabrizio D'ASCENZO ◽  
Elena CAVARRETTA ◽  
Giacomo FRATI ◽  
Matteo ANSELMINO ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Potential Role ◽  
All Cause Mortality

The Potential Role of a Corticotropin-Releasing Factor Receptor-1 Antagonist in Psychiatric Disorders

CNS Spectrums ◽  
2008 ◽  
Vol 13 (6) ◽  
pp. 467-483 ◽  
Author(s):  
Stephen M. Stahl ◽  
Dana D. Wise
Keyword(s):  
Stress Response ◽  
Psychiatric Disorders ◽  
Stress Responses ◽  
Potential Role ◽  
Corticotropin Releasing Factor ◽  
Recovering Alcoholic ◽  
Mood And Cognition ◽  
Pituitary Adrenal Axis

The hypothalamic-pituitary-adrenal axis is a key mediator of the stress response in humans. The corticotropin-releasing factor (CRF) type 1 receptor (CRFR-1) in the pituitary gland is a gatekeeper for that response, and the CRFR-1 receptor is also present in many other mood- and cognition-related neural structures. Behaviorally, a number of relationships between stress and psychiatric disorders can be observed: chronic or repeated stress is associated with onset of depression; stressors can cause a recovering alcoholic to relapse; overactive stress responses mark many anxiety disorders; and insomnia can arise from an overactive stress response. Thus, a CRFR-1 antagonist could be useful for treating or preventing the consequences of CRF-mediated stress in depression, anxiety, insomnia, and substance abuse.

scholarly journals Prognostic value of arterial stiffness measurements in cardiovascular disease, diabetes, and its complications: The potential role of sodium‐glucose co‐transporter‐2 inhibitors

2020 ◽  
Vol 22 (4) ◽  
pp. 562-571 ◽  
Author(s):  
Dimitrios Patoulias ◽  
Christodoulos Papadopoulos ◽  
Konstantinos Stavropoulos ◽  
Ioanna Zografou ◽  
Michael Doumas ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Arterial Stiffness ◽  
Prognostic Value ◽  
Potential Role

scholarly journals STRESS AND HYPERTENSION

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Mr. Israel Jeba Prabu ◽  
Dr. C.P Sharma
Keyword(s):  
Cell Phone ◽  
Cardiovascular Health ◽  
Acute Stress ◽  
Healthcare Systems ◽  
Stressful Events ◽  
System Failure ◽  
Public Health Burden ◽  
The Third ◽  
Health Burden ◽  
Over Time

ABSTRACT Stress is body's reaction to a challenge or demand. In short bursts, stress can be positive, such as when it helps to avoid danger or meet a deadline. High blood pressure (BP) is ranked as the third most important risk factor for attributable burden of disease in south Asia (2010). Hypertension (HTN) exerts a substantial public health burden on cardiovascular health status and healthcare systems in India. Sympathetic responses to acute stress are well documented, but the process by which stress contributes to sustained BP elevation over time is not well understood. It may be repeated activation of this system, failure to return to resting levels following stressful events, failure to habituate to repeated stressors of the same type, or some combination that is responsible for the development of hypertension. A variety of free meditation or mindfulness apps are available to download onto cell phone or tablet. There are also plenty of guided meditations available online. When we don’t get enough rest, it affects our mood. Being tired can also impair judgment and cause brain fog. It’s important to take time for them self and make sure individual getting enough rest Key words: awareness, control, hypertension, stress.

scholarly journals Plasticizers and Cardiovascular Health: Role of Adipose Tissue Dysfunction

2021 ◽  
Vol 11 ◽  
Author(s):  
Mikyla A. Callaghan ◽  
Samuel Alatorre-Hinojosa ◽  
Liam T. Connors ◽  
Radha D. Singh ◽  
Jennifer A. Thompson
Keyword(s):  
Cardiovascular Disease ◽  
Adipose Tissue ◽  
Adverse Effects ◽  
Cardiovascular Health ◽  
The United States ◽  
Current Evidence ◽  
Endocrine Disrupting ◽  
And Function

Since the 1950s, the production of plastics has increased 200-fold, reaching 360 million tonnes in 2019. Plasticizers, additives that modify the flexibility and rigidity of the product, are ingested as they migrate into food and beverages. Human exposure is continuous and widespread; between 75 and 97% of urine samples contain detectable levels of bisphenols and phthalates, the most common plasticizers. Concern over the toxicity of plasticizers arose in the late 1990s, largely focused around adverse developmental and reproductive effects. More recently, many studies have demonstrated that exposure to plasticizers increases the risk for obesity, type 2 diabetes, and cardiovascular disease (CVD). In the 2000s, many governments including Canada, the United States and European countries restricted the use of certain plasticizers in products targeted towards infants and children. Resultant consumer pressure motivated manufacturers to substitute plasticizers with analogues, which have been marketed as safe. However, data on the effects of these new substitutes are limited and data available to-date suggest that many exhibit similar properties to the chemicals they replaced. The adverse effects of plasticizers have largely been attributed to their endocrine disrupting properties, which modulate hormone signaling. Adipose tissue has been well-documented to be a target of the disrupting effects of both bisphenols and phthalates. Since adipose tissue function is a key determinant of cardiovascular health, adverse effects of plasticizers on adipocyte signaling and function may underlie their link to cardiovascular disease. Herein, we discuss the current evidence linking bisphenols and phthalates to obesity and CVD and consider how documented impacts of these plasticizers on adipocyte function may contribute to the development of CVD.

scholarly journals Cardiovascular Health and Risk Management in Cancer Survivors

2020 ◽  
Vol 18 (7.5) ◽  
pp. 1004-1006
Author(s):  
Javid J. Moslehi
Keyword(s):  
Cardiovascular Disease ◽  
Cancer Survivors ◽  
Cardiovascular System ◽  
Cardiovascular Health ◽  
Checkpoint Inhibitors ◽  
Angiogenesis Inhibitors ◽  
Cardiovascular Complications ◽  
Cancer Treatments ◽  
Cardiovascular Damage ◽  
Similar Risk

Cardio-oncology is a growing field, due to several factors. These include the recognition that similar risk factors predispose people to both cardiovascular disease and cancer. In addition, certain cancers affect the heart, and cancer treatments can have short-term and long-lasting deleterious effects on the cardiovascular system. More than 40 years ago, it became evident that anthracyclines and radiation cause heart damage, and since then the list of cancer treatments that can harm the cardiovascular system has grown to include more modern treatments, such as anti-HER2 agents and angiogenesis inhibitors. Most recently, immune checkpoint inhibitors (ICIs) have been added to the list of cancer treatments that cause cardiovascular damage. ICI-associated myocarditis is a relatively rare but fatal complication that develops rapidly after initiating immunotherapy. Oncologists should be aware of the potential cardiovascular complications of cancer treatments, and should assess the cardiovascular health of all patients about to undergo therapy. Cancer survivors should be assessed and advised about prevention and treatment that may be needed to address cardiovascular disease.

Cardiovascular Disease

2018 ◽  
Author(s):  
Mara Caroline ◽  
Ryan Bradley ◽  
Mimi Guarneri
Keyword(s):  
Cardiovascular Disease ◽  
Elderly Population ◽  
Cardiovascular Health ◽  
The Elderly ◽  
Nutrient Deficiencies ◽  
Comorbid Conditions ◽  
Increased Risk ◽  
Increased Susceptibility

The older population is challenging to treat for numerous reasons, including comorbid conditions and increased susceptibility to adverse drug reactions, limiting medical therapy. They are at increased risk for loneliness and depression, which strongly impacts their cardiovascular outcomes, and they also have different values, usually prioritizing quality of life over mortality objectives. Finally, the elderly are underrepresented in cardiovascular clinical trials, thus limiting the applicability of guideline recommendations. This chapter emphasizes the importance of a comprehensive assessment of individual circumstances when assessing cardiovascular health in the elderly population. The chapter focuses on the role of nutrition, resiliency, and exercise for the prevention and treatment of cardiovascular disease. Nutrient deficiencies commonly seen with cardiovascular drugs are also discussed, as well as specific integrative strategies for optimizing dyslipidemia, atrial fibrillation, and heart failure in this population.

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