Possible Involvement of Tight Junctions, Extracellular Matrix and Nuclear Receptors in Epithelial Differentiation
2011 ◽
Vol 2011
◽
pp. 1-10
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Keyword(s):
Tight junctions are intercellular junctions localized at the most apical end of the lateral plasma membrane. They consist of four kinds of transmembrane proteins (occludin, claudins, junctional adhesion molecules, and tricellulin) and huge numbers of scaffolding proteins and contribute to the paracellular barrier and fence function. The mutation and deletion of these proteins impair the functions of tight junctions and cause various human diseases. In this paper, we provide an overview of recent studies on transmembrane proteins of tight junctions and highlight the functional significance of tight junctions, extracellular matrix, and nuclear receptors in epithelial differentiation.
2018 ◽
Keyword(s):
1990 ◽
Vol 48
(3)
◽
pp. 60-61
Keyword(s):
1998 ◽
Vol 273
(10)
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pp. 5419-5422
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1998 ◽
Vol 142
(1)
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pp. 101-115
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Keyword(s):
1984 ◽
Vol 99
(6)
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pp. 2333-2335
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2018 ◽
STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion
2014 ◽
Vol 207
(4)
◽
pp. 535-548
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