scholarly journals Integrative Effects of FeedingAspergillus awamoriandfructooligosaccharideon Growth Performance and Digestibility in Broilers: Promotion Muscle Protein Metabolism

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Ahmed A. Saleh ◽  
Khairy Amber ◽  
Mohammed A. El-Magd ◽  
Mostafa S. Atta ◽  
Ahmed A. Mohammed ◽  
...  
Keyword(s):  
Growth Factor ◽  
Growth Performance ◽  
Protein Metabolism ◽  
Muscle Protein ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Aspergillus Awamori ◽  
Control Group ◽  
Treatment Groups ◽  
Muscle Protein Metabolism

This study was conducted to show the effect ofAspergillus awamori(AA),fructooligosaccharide(FOS), and combinedAspergillus awamoriandfructooligosaccharide(AA + FOS) on growth, digestibility, blood parameters, and expression of some growth-related genes. A total of 60 broiler chicks at the age of 15 d were divided into a control group (n=15) and 3 treatment groups. The control group was fed a basal diet, and the treatment groups were fed basal diets supplemented with 0.05% AA, 0.05% FOS, and combined of 0.05% AA and 0.05% FOS. Results from measurement of growth performance and digestibility revealed a significant increase in the body weight gain with improved feed conversion rate in the experimental groups. Interestingly, dry matter digestibility (DMD) and crude protein utilization (CPU) were improved. In addition, plasma total cholesterol and low density lipoprotein-cholesterol (LDL-C) were decreased, while plasma high density lipoprotein-cholesterol (HDL-C) was increased by feeding AA, FOS, and AA + FOS. Expressions of growth hormone secretagogue receptor (GHSR), insulin-like growth factor 1 (IGF-1), and insulin-like growth factor 1 receptor (IGF1R) were increased in experimental groups. In conclusion, the supplementation of eitherAspergillus awamoriorfructooligosaccharideor both improves digestibility and growth performance probably by promoting skeletal muscle protein metabolism.

scholarly journals Effects of Quercetin Supplementation on Lipid and Protein Metabolism after Classic Boxing Training

2017 ◽  
Vol 5 (4) ◽  
pp. 74
Author(s):  
Nevzat Demirci ◽  
Mehmet Akif Ziyagil
Keyword(s):  
Protein Metabolism ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Control Group ◽  
Physical Conditioning ◽  
Control Groups ◽  
Significant Difference ◽  
And Control ◽  
Metabolic Fitness

The metabolic fitness (MF) is a component of athletes’ physical conditioning. This study aims to investigate the effects of quercetin supplementation on Turkish Junior athletes’ lipid and protein metabolism relating to MF after one month classic boxing training. Totally 20 voluntary junior male athletes were separated into two equal groups as the experimental group (EG) and control group (CG). The participants were supplemented with 500 mg quercetin fifteen minutes before each workout in one month boxing training program. Blood samples during pre and post training were taken from athletes in order to determine metabolic fitness related parameters. Lipid profile contains low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), trigliserid (TG), total cholesterol (TC) variables while protein metabolism includes the albumin, total protein, direct bilirubin and total bilirubin parameters. The Mann Whitney U analyzes were used for comparison of the means between experimental and control groups during pre and posttest and between pre and post test results in experimental and control groups. This study showed that EG had a similar physical characteristic with CG. There were significant decrease in TC and LDL-C and an increase in HDL-C in EG while there was only significant increase in HDL-C of in controls. A significant difference of HDL-C was observed between EG and CG during pretest. In other side, TC and LDL-C and HDL-C were significantly differentiated between EG and CG during posttest. Conclusion: it can be concluded that quercetin plays an important role on lipid metabolism not protein.

scholarly journals Effects of dietary dihydropyridine supplementation on growth performance and lipid metabolism of broiler chickens

2010 ◽  
Vol 55 (No. 3) ◽  
pp. 116-122 ◽  
Author(s):  
Z.Y. Niu ◽  
F.Z. Liu ◽  
Y.N. Min ◽  
W.C. Li
Keyword(s):  
Lipid Metabolism ◽  
Growth Performance ◽  
Lipase Activity ◽  
Feed Efficiency ◽  
Apolipoprotein B ◽  
Density Lipoprotein ◽  
Abdominal Fat ◽  
Lipoprotein Cholesterol ◽  
Optimum Dose ◽  
Control Group

An experiment was conducted to investigate the effects of dihydropyridine supplementation on growth performance and lipid metabolism of broilers. A total of 480 one-day-old female Arbor Acres broiler chicks were randomly divided into four groups, each group had six replications of 20 birds. Each group was fed a maize-soybean meal diet supplemented with 0, 100, 200, 300 mg/kg dihydropyridine, respectively, for six weeks. At 42 days of age, body weight and feed intake were not affected by dihydropyridine, while feed efficiency was significantly increased by 8.4%, 15.0% and 12.0%, respectively (<I>P </I>&lt; 0.05). The percentage of abdominal fat and the percentage of liver fat were reduced by 24.5%, 25.9%, 23.3%, and 23.6%, 26.7%, 26.0%, respectively (<I>P </I>&lt; 0.05). The higher level of dietary dihydropyridine (200 or 300 mg/kg) increased the hormone-sensitive triglyceride lipase activity in liver and abdominal fat (<I>P </I>&lt; 0.05). The lipoprotein lipase activity in abdominal fat was significantly decreased by dihydropyridine (<I>P </I>&lt; 0.05). The activity of glucose-6-phosphate dehydrogenase and malic dehydrogenase in liver was significantly reduced, whereas the isocitrate dehydrogenase activity in liver was not affected by dietary dihydropyridine. The content of cAMP was significantly increased by dihydropyridine, but malondialdehyde content was decreased (<I>P </I>&lt;&nbsp;0.05). Dihydropyridine at doses of 100 and 200 mg/kg increased apolipoprotein B (<I>P </I>&lt; 0.05), but 300 mg/kg dihydropyridine had no effect on apolipoprotein B compared with the control group. Triiodothyronine was significantly increased by dietary dihydropyridine (<I>P </I>&lt; 0.05). There were no differences in apolipoprotein A, cholesterol, trigly-cerides, high density lipoprotein-cholesterol, very low density lipoprotein-cholesterol, thyroxine and insulin among dietary treatments. It is concluded that supplementing dihydropyridine has a beneficial effect on feed efficiency and lipid metabolism of broilers, and that 200 mg/kg dihydropyridine supplementation is the optimum dose.

scholarly journals Growth Performance, Nutrient Digestibility, Biochemical Properties, Hematological Traits, and Intestinal Histopathology of Broiler Chicks Fed Mannan Oligosaccharides

2021 ◽  
Vol 11 (4) ◽  
pp. 621-633
Author(s):  
Abdallah Ali Ghazalah ◽  
Mohamed Ahmed Fouad El-Manylawi ◽  
Hady Fathy Abbas Motawe ◽  
Marwa Salah Khattab ◽  
Yara Ibrahem Youssef
Keyword(s):  
Growth Performance ◽  
Broiler Chickens ◽  
Density Lipoprotein ◽  
Basal Diet ◽  
Blood Parameters ◽  
Nutrient Digestibility ◽  
The Other ◽  
Control Group ◽  
Broiler Chicks ◽  
Treatment Groups

, , , , and Antibiotics as growth promoters in poultry diets are currently restricted, so other feed additives, such as prebiotics and probiotics, have been suggested as an antibiotics alternative to improve the performance and gut health of poultry. The current experiment was conducted to study the effects of adding Mannan oligosaccharides (MOS) as a potential replacement for an antibiotic on productive performance, nutrient digestibility, some blood parameters, and caecal microbiota of broiler chickens. For conducting the current research experiment, a total of 180 one–day old Ross broiler chicks were randomly divided into one control group fed a basal diet and four dietary treatments with six replicates for each treatment. The treatment groups were fed a basal diet supplemented with different levels of MOS 0.5, 1, and 2 g/Kg diet and Lincomycin 4.4 mg/Kg diet during 35 days of the feeding trial. With exception of the growing period, the group fed a basal diet supplemented with 2 g MOS/Kg feed had considerably higher body weight and weight gain, while having the lowest feed consumption and best feed conversion ratio compared to the other treatment groups, during all experimental periods. Moreover, dietary supplementation of MOS resulted in a significant decrease in the counts of caecal E. coli and Enterococcus, while Lactobacillus and Yeast bacteria counts were significantly higher, compared to non-supplemented groups. Broiler chicks having a 2 g MOS/kg diet recorded lower values of cholesterol, low-density lipoprotein (LDL), urea, and liver enzymes, including Aspartate transaminase (AST) and Alanine aminotransferase (ALT), while they recorded significantly higher high-density lipoprotein (HDL), compared to the other experimental groups. Group treated with MOS 2 g/Kg feed improved digestibility of crude protein, ether extract, crude fiber, nitrogen-free extract, and organic matter, compared to the control group, Additionally, MOS supplementation also increased the intestinal villi length, width, and crypt depth and decreased intestinal inflammation, compared to the control group. In conclusion, supplementation of MOS at 2 g/kg diet improved growth performance, digestibility, and blood parameters without having adverse effects on the intestine of broiler chickens, comparable to the Lincomycin.

Effects of dietary vitamin B6 on the skeletal muscle protein metabolism of growing rabbits

2017 ◽  
Vol 57 (10) ◽  
pp. 2007
Author(s):  
G. Y. Liu ◽  
Z. Y. Wu ◽  
Y. L. Zhu ◽  
L. Liu ◽  
F. C. Li
Keyword(s):  
Skeletal Muscle ◽  
Growth Factor ◽  
Protein Metabolism ◽  
Vitamin B6 ◽  
Muscle Protein ◽  
Dietary Vitamin ◽  
Skeletal Muscle Protein ◽  
Muscle Weight ◽  
Muscle Protein Metabolism ◽  
Leg Muscle

This study aimed to evaluate the effects of dietary vitamin B6 on the skeletal muscle protein metabolism and expression of transcription and growth factor of growing rabbits. Two hundred, healthy, rabbits with similar bodyweights were randomly assigned to one of five dietary groups with 40 animals per group. The dietary groups consisted of the following different vitamin B6 supplementation levels: 0, 5, 10, 20 and 40 mg/kg. The feeding trial lasted 60 days. The results showed that dietary vitamin B6 elicited significant effects on the fore and hind leg muscle ratio (the fore and hind leg muscle weight/the liveweight; P < 0.05) and on serum total amino acids (T-AA), blood urea and insulin-like growth factor 1 (IGF1) content (P < 0.05). Additionally, expression of IGF1, myogenic determination factor (MYOD) and myogenin (MYOG), myocyte regulation factor 5 (MYF5), myostatin (MSTN) and WW domain-containing E3 proteasome ubiquitin ligase 1 (WWP1) mRNA in the loin (M. longissimus dorsi) were affected by vitamin B6 in diets (P < 0.05). The immunoblot analysis revealed that dietary vitamin B6 elicited significant effects on IGF1, MYOG and WWP1 expression in the loin (P < 0.05). Our results indicate that the addition of dietary vitamin B6 can significantly alter the protein metabolism of growing rabbits and that an appropriate vitamin B6 supplementation level is 20 mg/kg for 3–5-month-old growing rabbits (the basic diet vitamin B6 content was 4.51 mg/kg).

scholarly journals Androstenedione Does Not Stimulate Muscle Protein Anabolism in Young Healthy Men1

2000 ◽  
Vol 85 (1) ◽  
pp. 55-59
Author(s):  
Blake B. Rasmussen ◽  
Elena Volpi ◽  
Dennis C. Gore ◽  
Robert R. Wolfe
Keyword(s):  
Protein Metabolism ◽  
Muscle Protein ◽  
Muscle Protein Synthesis ◽  
Compartment Model ◽  
Plasma Testosterone ◽  
Control Group ◽  
Improve Performance ◽  
Muscle Protein Metabolism ◽  
Three Compartment Model ◽  
Muscle Biopsies

Androstenedione is the immediate precursor of testosterone. Androstenedione intake has been speculated to increase plasma testosterone levels and muscle anabolism. Thus, androstenedione supplements have become widely popular in the sport community to improve performance. This study was designed to determine whether 5 days of oral androstenedione (100 mg/day) supplementation increases skeletal muscle anabolism. Six healthy young men were studied before the treatment period and after 5 days of oral androstenedione supplementation. Muscle protein turnover parameters were compared to those of a control group studied twice as well and receiving no treatment. We measured muscle protein kinetics using a three-compartment model involving infusion of l-[ring-2H5]phenylalanine, blood sampling from femoral artery and vein, and muscle biopsies. Plasma testosterone, androstenedione, LH, and estradiol concentrations were determined by RIA. After ingestion of oral androstenedione, plasma testosterone and LH concentrations did not change from basal, whereas plasma androstenedione and estradiol concentrations were significantly increased (P &lt; 0.05). Compared to a control group, androstenedione did not affect muscle protein synthesis and breakdown, or phenylalanine net balance across the leg. We conclude that oral androstenedione does not increase plasma testosterone concentrations and has no anabolic effect on muscle protein metabolism in young eugonadal men.

Dietary supplementation with avilamycin and Lactobacillus acidophilus effects growth performance and the expression of growth-related genes in broilers

2020 ◽  
Vol 60 (14) ◽  
pp. 1704 ◽  
Author(s):  
A. A. Saleh ◽  
K. Amber ◽  
A. A. Mohammed
Keyword(s):  
Growth Factor ◽  
Growth Performance ◽  
Feed Intake ◽  
Lactobacillus Acidophilus ◽  
Feed Efficiency ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Basal Diet ◽  
Control Group ◽  
Lipid Levels

Context The use of antibiotics in poultry production is appropriate; however, it brings a high risk of dissemination of antibiotic-resistant strains of pathogenic and non-pathogenic bacteria and their further transmission to humans via the food chain. Aims The effects of supplementation with Lactobacillus acidophilus (a probiotic) or avilamycin (an in-feed antibiotic growth promoter), on growth performance, digestibility, plasma lipid levels, and the expression of certain growth-related genes were investigated. Methods In total, 135 15-day-old broiler chicks were divided into three groups (n = 45): a control group and two treatment groups. Each treatment group was then further divided into three replicates (15 birds each). The control group was fed a basal diet; the second group received basal diet supplemented with avilamycin (0.1 g/kg); the third group received basal diet plus L. acidophilus (0.1 g/kg). Growth performance (bodyweight, feed intake and feed-conversion ratio) was measured. Digestibility and gene expression were measured at the end of the experiment. Key results Greatest bodyweight gain was achieved in the L. acidophilus-fed chicks, which were significantly (P &lt; 0.05) heavier than the control chicks and the avilamycin-fed chicks. Addition of avilamycin or L. acidophilus to the diet also significantly improved feed efficiency (P &lt; 0.05) compared with the control. Although the digestibility of dry matter, crude protein and crude fibre significantly improved in the two experimental groups compared with the control, ether extract was not affected. In addition, plasma total cholesterol, triglyceride and low-density-lipoprotein cholesterol levels were significantly (P &lt; 0.05) decreased whereas plasma high-density-lipoprotein cholesterol was significantly (P &lt; 0.05) increased in the L. acidophilus group compared with the control. Expression of the genes for growth hormone secretagogue receptor (GHSR), insulin-like growth factor 1 (IGF-1) and insulin-like growth factor 1 receptor (IGF1R) was remarkably upregulated in the skeletal muscles of the two experimental groups. Conclusions Supplementation with L. acidophilus (0.1 g/kg) in the broiler diet had positive effects on growth, feed intake, feed efficiency, digestibility, and plasma lipid levels of the broilers. Implications Lactobacillus acidophilus might be a more useful additive in broiler feed than antibiotic growth promoters such as avilamycin.

Hypercortisolemia alters muscle protein anabolism following ingestion of essential amino acids

2003 ◽  
Vol 284 (5) ◽  
pp. E946-E953 ◽  
Author(s):  
Douglas Paddon-Jones ◽  
Melinda Sheffield-Moore ◽  
Daniel L. Creson ◽  
Arthur P. Sanford ◽  
Steven E. Wolf ◽  
...  
Keyword(s):  
Amino Acids ◽  
Protein Metabolism ◽  
Muscle Protein ◽  
Sodium Succinate ◽  
Essential Amino Acids ◽  
Constant Infusion ◽  
Control Group ◽  
Before And After ◽  
Intravenous Saline ◽  
Muscle Protein Metabolism

Debilitating injury is accompanied by hypercortisolemia, muscle wasting, and disruption of the normal anabolic response to food. We sought to determine whether acute hypercortisolemia alters muscle protein metabolism following ingestion of a potent anabolic stimulus: essential amino acids (EAA). A 27-h infusion (80 μg · kg−1 · h−1) of hydrocortisone sodium succinate mimicked cortisol (C) levels accompanying severe injury (>30 μg/dl), (C + AA; n = 6). The control group (AA) received intravenous saline ( n = 6). Femoral arteriovenous blood samples and muscle biopsies were obtained during a primed (2.0 μmol/kg) constant infusion (0.05 μmol · kg−1 · min−1) ofl-[ ring-2H5]phenylalanine before and after ingestion of 15 g of EAA. Hypercortisolemia [36.5 ± 2.1 (C + AA) vs. 9.0 ± 1.0 μg/dl (AA)] increased postabsorptive arterial, venous, and muscle intracellular phenylalanine concentrations. Hypercortisolemia also increased postabsorptive and post-EAA insulin concentrations. Net protein balance was blunted (40% lower) following EAA ingestion but remained positive for a greater period of time (60 vs. 180 min) in the C + AA group. Thus, although differences in protein metabolism were evident, EAA ingestion improved muscle protein anabolism during acute hypercortisolemia and may help minimize muscle loss following debilitating injury.

1460 Muscle protein metabolism of growing Holstein × Gyr heifers

2016 ◽  
Vol 94 (suppl_5) ◽  
pp. 709-709
Author(s):  
F. A. S. Silva ◽  
S. C. Valadares Filho ◽  
L. N. Rennó ◽  
S. A. Santos ◽  
D. Zanetti ◽  
...  
Keyword(s):  
Protein Metabolism ◽  
Muscle Protein ◽  
Muscle Protein Metabolism
Sign in / Sign up

Export Citation Format

Share Document