scholarly journals Pharmacology and Phytochemistry of Oleo-Gum Resin ofCommiphora wightii(Guggulu)

Scientifica ◽  
2015 ◽  
Vol 2015 ◽  
pp. 1-14 ◽  
Author(s):  
Prerna Sarup ◽  
Suman Bala ◽  
Sunil Kamboj
Keyword(s):  
Amino Acids ◽  
Wild Population ◽  
Therapeutic Potential ◽  
Chemical Constituents ◽  
Volatile Oil ◽  
Iucn Red List ◽  
Red List ◽  
Commiphora Wightii ◽  
Commiphora Mukul ◽  
Lipids Metabolism

Guggulu is an oleo-gum resin which exudes out as a result of injury from the bark ofCommiphora wightii(Arnott) Bhandari [syn.  Commiphora mukul(Hook. Ex Stocks) Engl;Balsamodendron mukul(Hook. Ex Stocks); Family, Burseraceae]. It has been used in theAyurvedasince time immemorial for the treatment of variety of disorders such as inflammation, gout, rheumatism, obesity, and disorders of lipids metabolism. It is a mixture of phytoconstituents like volatile oil which contains terpenoidal constituents such as monoterpenoids, sesquiterpenoids, diterpenoids, and triterpenoids; steroids; flavonoids; guggultetrols; lignans; sugars; and amino acids. This review is an effort to compile all the information available on all of its chemical constituents which are responsible for its therapeutic potential. The wild occurrence of this species is restricted mainly to the dry regions of Rajasthan and Gujarat States of India, and the bordering regions of Pakistan. Oleo-gum resin, guggulu, tapped from the stems of this species, is consumed in high volumes by the Indian herbal industries. There has been a decline in its wild population over the last several decades, as a result of habitat loss and degradation, coupled with unregulated harvesting and tapping of oleo-gum resin. This species is consequently assessed as Critically Endangered and enlisted in the IUCN red list of threatened species.

Primordial science and pioneering approaches of guggul for chronic ailments – A modernized review

2020 ◽  
Vol 7 (2) ◽  
pp. 14-20
Author(s):  
Jamal Basha D ◽  
Kumar P R ◽  
Ranganayakulu D
Keyword(s):  
Water Solubility ◽  
Therapeutic Potential ◽  
Chemical Constituents ◽  
Signs And Symptoms ◽  
Dosage Forms ◽  
The Novel ◽  
Lipids Metabolism ◽  
Clinical Conditions ◽  
Novel Drug ◽  
Conventional Dosage

An oleo gum resin guggulu is a product which obtained as a result of gummosis from the bark of Commiphora wightii (Arnott) Bhandari [syn. Commiphoramukul (Hook. Ex Stocks) Family, Burseraceae]. It has been known for its immense applicability in the Ayurveda since time immemorial for the treatment of variety of disorders such as inflammation, gout, rheumatism, impotence, leprosy, obesity, and disorders of lipids metabolism. It is a mixture of phytoconstituents like terpenoids, steroids, flavonoids, guggultetrols, lignans, sugars, and amino acids. This review is an effort to compile all the information available on all of its chemical constituents which are responsible for its therapeutic potential, limitation of guggul extracts and the necessity of novel principles for gum guggul. Nowadays, Guggul is available as the marketed formulation for curing numerous clinical conditions and is accessible in combination with various other ingredients. Though conventional dosage form shows the dominance as patient compliance and easy availability, yet it has found to pose the problems like dose fluctuation, peak-valley effect, non-adjustment of the administered drug, invasiveness etc. Guggul lacks its desired effect due to its low bioavailability and water solubility. This makes it a partial or a deficient therapy for remedy of many signs and symptoms. Novel drug delivery system (NDDS), a new approach and has excluded many of drawbacks exhibited by conventional dosage forms. Some of the novel dosage forms of guggul has been formed like nanoparticles, nanovesicles, gugglusomes and proniosomal gel. But still, the novel formulations for guggul has its less outspread in the market. Guggul can be executed as a profitable drug using NDDS. There is a need to highlight the unidentified and unexplained facts about guggul so as to make it more efficacious and effective in terms of bioavailability and aqueous insolubility.

scholarly journals Bilateral Intratesticular Spermatoceles in a Critically Endangered Dama Gazelle (Nanger dama mhorr)

2020 ◽  
Vol 2020 ◽  
pp. 1-3
Author(s):  
Riley E. Thompson ◽  
Holly J. Haefele ◽  
Daniel P. O’Neil ◽  
Budhan S. Pukazhenthi
Keyword(s):  
Adult Male ◽  
Threatened Species ◽  
Wild Population ◽  
Iucn Red List ◽  
Red List ◽  
Critically Endangered ◽  
Normal Sperm ◽  
The Us ◽  
In Captivity

Dama gazelles (Nanger dama mhorr) are considered critically endangered by the IUCN Red List of Threatened Species since the wild population is comprised of fewer than 200 animals. Several zoos in Europe and some private ranches in the US (Texas) maintain this species in captivity as a hedge against extinction. A routine reproductive exam on an adult male revealed bilateral cysts in the testicular parenchyma. The fluid in the cysts contained copious, moderately progressive motile spermatozoa. Following examination, the gazelle was diagnosed with bilateral intratesticular spermatoceles. Electroejaculation yielded 1.5 ml of semen containing 387×106 total sperm with 50% motility and 45% morphologically normal sperm. The spermatoceles did not appear to cause pain or dysfunction, so no treatment was performed at this time. Since fewer than 10 animals are managed in captivity in the US, no intervention (castration/hemicastration) was considered.

scholarly journals The First Record of Intestinal Ciliates from the Mountain Zebra (Equus zebra) in South Africa

2021 ◽  
Vol 59 (3-4) ◽  
pp. 149-155
Author(s):  
Olga Kornilova ◽  
Klara Tsushko ◽  
Ludmila Chistyakova
Keyword(s):  
South Africa ◽  
Wild Population ◽  
First Record ◽  
Iucn Red List ◽  
Red List ◽  
Western Cape ◽  
First Report ◽  
Ciliate Species ◽  
The World ◽  
First Time

This paper is a first report on species of endosymbiotic ciliates (Litostomatea, Trichostomatia) inhabiting the intestine of zebras in South Africa. Ciliates from Mountain Zebra were investigated for the first time in the world. The wild population of mountain zebras in general and the Cape Mountain Zebra subspecies in particular is low in numbers: this species is included as vulnerable in the IUCN Red List. Approximately 15 species of trichostome ciliates from 9 different genera were found in the samples collected from wild zebras in Western Cape, South Africa. Some of the ciliate species are also common to horses and other equids, while others are unique for zebras. The ciliates of Triplumaria genus common to elephants and rhinoceroses, and the species Blepharosphaera ceratotherii previously described in rhinoceroses were found in equids for the first time.

scholarly journals A New Flavonoid from Malaysian Dipterocarpus cornutus

2021 ◽  
Vol 21 (5) ◽  
pp. 1132
Author(s):  
Wan Zuraida Wan Mohd Zain ◽  
Liliwirianis Nawi ◽  
Norizan Ahmat ◽  
Che Puteh Osman ◽  
Yaya Rukayadi
Keyword(s):  
East Asia ◽  
Chemical Constituents ◽  
Stem Bark ◽  
Iucn Red List ◽  
Red List ◽  
South East Asia ◽  
Phytochemical Study ◽  
The Family ◽  
Coumarin 6 ◽  
Comprehensive Study

Dipterocarpus cornutus Dyer is commonly known as ‘keruing’. It belongs to the family of Dipterocarpaceae, an important timber family in South East Asia. D. cornutus is listed as critically endangered on IUCN Red List. Since no comprehensive study has been documented on the chemical constituents of D. cornutus, there is an urgent need to study this plant comprehensively. Phytochemical study of the stem bark of D. cornutus afforded a new flavonoid (1) and nine known compounds, which consist of flavonoids (2, 3), oligostilbenoids (4, 5, 7, 8, 9, 10), and coumarin (6). The finding of the study contributes to the chemotaxonomic differentiation in the plants of the tribe Dipterocarpae.

Typification of Ardisia blatteri (Primulaceae)

Phytotaxa ◽  
2017 ◽  
Vol 295 (1) ◽  
pp. 92
Author(s):  
RIJUPALIKA ROY ◽  
ANIRBAN ROY ◽  
ARABINDA PRAMANIK
Keyword(s):  
Threatened Species ◽  
Western Ghats ◽  
Chemical Constituents ◽  
Iucn Red List ◽  
Red List ◽  
Traditional Medicines ◽  
Medicinal Properties

Ardisia blatteri Gamble (1921: 121) is endemic to India and occurs in the southern part of Western Ghats (Dhanasekaran et al. 2016). This species has been considered as ‘Endangered’ in IUCN Red List of Threatened Species (IUCN 2016). The plants are rich in chemical constituents like alkaloids, tannins, saponins, anthraquinones, phenols, terpenoids and flavonoids, coumarins, steroids and phytosteroids and are used in traditional medicines (Dhanasekaran et al. 2016) for curing fever, cough, rheumatism, inflammation and many more ailments. The medicinal properties of this important plant require further research.

Phytochemical, Pharmacological Activities and Ayurvedic Significances of Magical Plant Mimosa pudica Linn

2020 ◽  
Vol 17 ◽  
Author(s):  
Vijay Kumar
Keyword(s):  
Therapeutic Potential ◽  
Wide Spectrum ◽  
Chemical Constituents ◽  
Future Research ◽  
Mimosa Pudica ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Traditional Medicines ◽  
Crude Extracts ◽  
Anti Cancer

: Mimosa pudica Linn is an integrated part of Traditional Medicines Systems of India, China, Africa, Korea and America. It has been used from centuries in traditional medicines to cure different diseases like fever, diabetes, constipation, jaundice, ulcers, biliousness, and dyspepsia. It is an important ingredient of wide class of herbal formulations. To assess the scientific evidence for therapeutic potential of Mimosa pudica Linn and to identify the gaps for future research. The available information on the ethno-medicinal uses, phytochemistry, pharmacology and toxicology of Mimosa pudica Linn was collected via a library and electronic searches in Sci-Finder, Pub-Med, Science Direct, Google Scholar for the period, 1990 to 2020. In traditional medicinal systems, variety of ethno-medicinal applications of Mimosa pudica Linn has been noticed. Phytochemical investigation has resulted in identification of 40 well known chemical constituents, among which alkaloids, phenols and flavionoids are the predominant groups. The crude extracts and isolates have exhibited a wide spectrum of in vitro and in vivo pharmacological activities including anti-cancer, anti-inflammation, osteoporosis, neurological disorders, hypertension etc.. To quantify the Mimosa pudica Linn and its formulations, analytical techniques like HPLC and HPTLC has shown dominancy with good range of recovery and detection limit. Mimosa pudica Linn is the well-known herb since an ancient time. The pharmacological results supported some of the applications of Mimosa pudica Linn in traditional medicine systems. Perhaps, the predominance of alkaloids, phenols and flavionoids are responsible for the pharmacological activities the crude extracts and isolates of Mimosa pudica Linn. Further, there is need to isolate and evaluate the active chemical constituents of Mimosa pudica Linn having significant medicinal values. In future, it is important to study the exact mechanism associated with the phytochemicals of Mimosa pudica Linn especially on anti-cancer activities. Notably, toxicity studies on Mimosa pudica Linn are limited which are to be explored in future for the safe application of Mimosa pudica Linn and its formulations.

scholarly journals Giant otter Pteronura brasiliensis density and abundance in Llanos Orientales de Colombia in the Orinoco basin

Oryx ◽  
2020 ◽  
pp. 1-4
Author(s):  
Germán Garrote ◽  
Beyker Castañeda ◽  
Jose Manuel Escobar ◽  
Laura Pérez ◽  
Brayan Marín ◽  
...  
Keyword(s):  
South America ◽  
Population Size ◽  
20Th Century ◽  
Conservation Status ◽  
Species Conservation ◽  
Iucn Red List ◽  
Red List ◽  
Recreational Fishing ◽  
Pteronura Brasiliensis ◽  
Direct Counts

Abstract The giant otter Pteronura brasiliensis, categorized as Endangered on the IUCN Red List, was once widely distributed throughout South America. By the middle of the 20th century the giant otter had become locally extinct along the main rivers of the Orinoco basin. Although some populations seem to have recovered, the paucity of information available does not permit a full evaluation of the species' conservation status. The objective of this study was to estimate the abundance and density of the giant otter population along the Orinoco river in the municipality of Puerto Carreño, Vichada, Colombia, where there is important commercial and recreational fishing. Thirty-nine linear km were surveyed, repeatedly, with a total of 315 km of surveys. Population size was estimated by direct counts of individuals. All individuals detected were photographed and identified individually from their throat pelage patterns. In total, 30 otters were identified, giving a minimum density of 0.77 individuals per km, one of the highest reported for the species in Colombia. Given the high density in this well-developed area, our results highlight the importance of this population for the conservation of the species.

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