scholarly journals Intranodal Palisaded Myofibroblastoma in a Submandibular Lymph Node

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Leila Bouhajja ◽  
Raja Jouini ◽  
Olfa Khayat ◽  
Wafa Koubâa ◽  
Chiraz Mbarek ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Spindle Cell ◽  
Cell Tumor ◽  
Spindle Cell Tumor ◽  
Cervical Lymph Nodes ◽  
Histological Features ◽  
Submandibular Lymph Node ◽  
Intranodal Palisaded Myofibroblastoma

Intranodal palisaded myofibroblastoma (IPM), also known as “intranodal hemorrhagic spindle cell tumor with amianthoid fibers,” is a rare benign mesenchymal tumor originating from smooth muscle cells and myofibroblasts, often with the presence of amianthoid fibers. Usually IPM affects inguinal lymph nodes, but three cases have been described in the submandibular and cervical lymph nodes. We report a new case of a 44-year-old women with submandibular mass. Cervical ultrasound showed a suspect right submandibular adenomegaly. The patient underwent an excision of the submandibular mass. Histological features of the tumor include an encapsulated fusocellular proliferation, with nuclear palisading, amianthoid fibers, hemosiderin pigment, and extravasated erythrocytes. In the light of these results, we made the diagnosis of IPM. No recurrence was found 5 years after surgery.

Primary Spindle Cell Tumor of Lymph Node with “Amianthoid” Fibers: A Histological, Immunohistochemical and Ultrastructural Study

1993 ◽  
Vol 17 (2) ◽  
pp. 195-205 ◽  
Author(s):  
Francesco Tanda ◽  
Giovannino Massarelli ◽  
Antonio Cossu ◽  
Luisanna Bosincu ◽  
Sergio Cossu ◽  
...  
Keyword(s):  
Lymph Node ◽  
Ultrastructural Study ◽  
Spindle Cell ◽  
Cell Tumor ◽  
Spindle Cell Tumor

scholarly journals A rare lesion of cervical lymph nodes: Angiomyomatous hamartoma

2021 ◽  
Vol 8 (3) ◽  
pp. 187-188
Author(s):  
Mecdi Gurhan Balci ◽  
Mahir Tayfur
Keyword(s):  
Smooth Muscle ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Smooth Muscle Cells ◽  
Histopathological Examination ◽  
Muscle Cells ◽  
Cervical Region ◽  
Pathology Laboratory ◽  
Cervical Lymph Nodes ◽  
Vascular Structures

Objective: Angiomyomatous hamartomas are extremely rare, tumor-like lesions of the lymph nodes. They are usually seen in the inguinal region lymph nodes. They are rarely seen in the lymph nodes of the cervical region. Histopathologically, fibrous tissues, smooth muscle cells, and vascular structures are seen in the lymph node structure. It is important to distinguish it from benign and malignant lesions of the lymph node. Case: A 1 cm diameter lymph node excision material removed from the cervical region of a 26-year-old male patient was sent to the pathology laboratory with a pre-diagnosis of lymphadenitis. 4- micron sections were taken from the paraffin blocks prepared from the tissues belonging to the lesion. The samples were examined by staining Hematoxylin-Eosin. In histopathological examination, it was found that almost all of the lymph node structure consisted of vascular structures and smooth muscle cells located on a fibrous ground. The case was reported as angiomyomatous hamartoma. Conclusion: Angiomyomatous hamartomas are extremely rare lesions of the cervical lymph nodes and their consideration in differential diagnosis will reduce the risk of possible diagnostic error.

Role of Clinical Palpation in Evaluation of Cervical Lymph Node in Oral Squamous Cell Carcinoma

2013 ◽  
Vol 1 (2) ◽  
pp. 02-06
Author(s):  
SM Anwar Sadat ◽  
Sufia Nasrin Rita ◽  
Shoma Banik ◽  
Md Nazmul Hasan Khandker ◽  
Md Mahfuz Hossain ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Oral Squamous Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Predictive Value ◽  
Cervical Lymph Node ◽  
Betel Quid ◽  
Cervical Lymph Nodes

A cross sectional study of 29 cases of oral squamous cell carcinoma with or without  cervical lymph node metastasis was done among Bangladeshi patients from January 2006 to December 2007. Majority of the study subjects (34.5%) belonged to the age group of 40-49 years. 58.6% of the study subjects were male, while remaining 41.4% of them were female. 51.7% of the lesions were located in the alveolar ridge where the other common sites were buccal mucosa (27.6%) and retro molar area (13.8%). Half of the study subjects (51.7%) were habituated to betel quid chewing followed by 37.9% and 10.3% were habituated to smoking and betel quid-smoking respectively. Grade I lesions was most prevalent (75.9%) in the study subjects.  Majority of cases presented with Stage IV lesions (55.2%). The sensitivity, specificity, positive predictive value, negative predictive value & accuracy of clinical palpation method for determining metastatic cervical lymph nodes were 93.33%, 64.29%, 73.68%, 90% and 79.3% respectively. Careful and repeated clinical palpation plays important role in evaluation of cervical lymph nodes though several modern techniques may help additionally in the management of oral cancer.DOI: http://dx.doi.org/10.3329/updcj.v1i2.13978 Update Dent. Coll. j. 2011: 1(2): 02-06

scholarly journals Cervical lymph node enlargement as the initial manifestation of rectal cancer

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tong-Hui Xie ◽  
Peng Su ◽  
Jian-Guo Hong ◽  
Hui Zhang
Keyword(s):  
Colorectal Cancer ◽  
Rectal Cancer ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Cervical Lymph Node ◽  
Clinical Manifestations ◽  
Initial Symptom ◽  
Cervical Lymph Nodes ◽  
Supraclavicular Lymph Nodes ◽  
Lymph Node Enlargement

Abstract Background Colorectal cancer is a very common malignant tumor worldwide. The clinical manifestations of advanced colorectal cancer include the changes in bowel habits, hematochezia, diarrhea, local abdominal pain and other symptoms. However, the colorectal cancer with an initial symptom of cervical lymph node enlargement is extremely rare. In this article, we report a case of rectal cancer presenting with cervical lymph nodes enlargement as the initial symptom. Case presentation A 57-year-old woman was admitted to our hospital for cervical lymph node enlargement which was accidentally detected during physical examination. Computed tomography scan revealed multiple enlarged lymph nodes in the neck. Cervical ultrasound showed normal thyroid gland and multiple left supraclavicular lymph nodes enlargement. The patient underwent lymph nodes biopsy and pathologic results showed metastatic adenocarcinoma. The subsequent lower gastrointestinal endoscopy revealed a mucosal bulge lesion located at rectus and biopsy revealed adenocarcinoma. The patient underwent rectal cancer resection. She is alive with no evidence of recurrence or new tumors 2 years after surgery. Conclusions Cervical lymph node metastasis is a rare metastatic way in colorectal cancer. This is the first case of rectal cancer presenting with cervical lymph nodes metastases as the initial symptom. Surgical resection combined with postoperative chemotherapy improved long-term prognosis of the patient. This rare metastatic way of rectal cancer should be paid attention for clinicians.

scholarly journals Theragnostic Glycol Chitosan-Conjugated Gold Nanoparticles for Photoacoustic Imaging of Regional Lymph Nodes and Delivering Tumor Antigen to Lymph Nodes

Nanomaterials ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1700
Author(s):  
In-Cheol Sun ◽  
SeongHoon Jo ◽  
Diego Dumani ◽  
Wan Su Yun ◽  
Hong Yeol Yoon ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Cancer Immunotherapy ◽  
Tumor Antigen ◽  
Tumor Antigens ◽  
Imaging System ◽  
Superior Performance ◽  
Glycol Chitosan ◽  
Cervical Lymph Nodes

Lymph node mapping is important in cancer immunotherapy because the morphology of lymph nodes is one of the crucial evaluation criteria of immune responses. We developed new theragnostic glycol-chitosan-coated gold nanoparticles (GC-AuNPs), which highlighted lymph nodes in ultrasound-guided photoacoustic (US/PA) imaging. Moreover, the ovalbumin epitope was conjugated GC-AuNPs (OVA-GC-AuNPs) for delivering tumor antigen to lymph node resident macrophage. In vitro studies proved the vigorous endocytosis activity of J774A.1 macrophage and consequent strong photoacoustic signals from them. The macrophages also presented a tumor antigen when OVA-GC-AuNPs were used for cellular uptake. After the lingual injection of GC-AuNPs into healthy mice, cervical lymph nodes were visible in a US/PA imaging system with high contrast. Three-dimensional analysis of lymph nodes revealed that the accumulation of GC-AuNPs in the lymph node increased as the post-injection time passed. Histological analysis showed GC-AuNPs or OVA-GC-AuNPs located in subcapsular and medullar sinuses where macrophages are abundant. Our new theragnostic GC-AuNPs present a superior performance in US/PA imaging of lymph nodes without targeting moieties or complex surface modification. Simultaneously, GC-AuNPs were able to deliver tumor antigens to cause macrophages to present the OVA epitope at targeted lymph nodes, which would be valuable for cancer immunotherapy.

Laparoscopic Liver Resection of a Desmoplastic Nested Spindle Cell Tumor of the Liver

2010 ◽  
Vol 76 (9) ◽  
pp. 184-185
Author(s):  
Caridad Marín ◽  
Ricardo Robles ◽  
Matilde Fuster ◽  
Pascual Parrilla
Keyword(s):  
Liver Resection ◽  
Laparoscopic Liver Resection ◽  
Spindle Cell ◽  
Cell Tumor ◽  
Spindle Cell Tumor

Assessment of cervical lymph node metastases using indirect computed tomography lymphography with iopamidol in a tongue VX2 carcinoma model

2011 ◽  
Vol 125 (8) ◽  
pp. 820-828 ◽  
Author(s):  
Y Shu ◽  
X Xu ◽  
Z Wang ◽  
W Dai ◽  
Y Zhang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lymph Node ◽  
Lymph Nodes ◽  
Lymph Node Metastases ◽  
Cervical Lymph Node ◽  
Cervical Lymph Nodes ◽  
Cervical Lymph Node Metastases ◽  
Computed Tomography Images ◽  
Vx2 Carcinoma ◽  
Node Metastases

AbstractObjective:To investigate the performance of indirect computed tomography lymphography with iopamidol for detecting cervical lymph node metastases in a tongue VX2 carcinoma model.Materials and methods:A metastatic cervical lymph node model was created by implanting VX2 carcinoma suspension into the tongue submucosa of 21 rabbits. Computed tomography images were obtained 1, 3, 5, 10, 15 and 20 minutes after iopamidol injection, on days 11, 14, 21 (six rabbits each) and 28 (three rabbits) after carcinoma transplantation. Computed tomography lymphography was performed, and lymph node filling defects and enhancement characteristics evaluated.Results:Indirect computed tomography lymphography revealed bilateral enhancement of cervical lymph nodes in all animals, except for one animal imaged on day 28. There was significantly slower evacuation of contrast in metastatic than non-metastatic nodes. A total of 41 enhanced lymph nodes displayed an oval or round shape, or local filling defects. One lymph node with an oval shape was metastatic (one of 11, 9.1 per cent), while 21 nodes with filling defects were metastatic (21/30, 70 per cent). The sensitivity, specificity, accuracy, and positive and negative predictive values when using a filling defect diameter of 1.5 mm as a diagnostic criterion were 86.4, 78.9, 82.9, 82.6 and 83.3 per cent, respectively.Conclusion:When using indirect computed tomography lymphography to detect metastatic lymph nodes, filling defects and slow evacuation of contrast agent are important diagnostic features.

Hyalinizing spindle cell tumor with giant rosettes of the omentum

2003 ◽  
Vol 29 (6) ◽  
pp. 388-391 ◽  
Author(s):  
Asako Koishi ◽  
Hideto Gomibuchi ◽  
Jun Inoue ◽  
Shigeki Minoura ◽  
Eisaku Itoh ◽  
...  
Keyword(s):  
Spindle Cell ◽  
Cell Tumor ◽  
Spindle Cell Tumor
Sign in / Sign up

Export Citation Format

Share Document