scholarly journals Tomographic Aspects of Advanced Active Pulmonary Tuberculosis and Evaluation of Sequelae following Treatment

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Rafael Barcelos Capone ◽  
Domenico Capone ◽  
Thiago Mafort ◽  
Roberto Mogami ◽  
Rosana de Souza Rodrigues ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Drug Therapy ◽  
Pulmonary Tuberculosis ◽  
Descriptive Study ◽  
Architectural Distortion ◽  
Cross Sectional ◽  
Chest Computed Tomography ◽  
Active Pulmonary Tuberculosis ◽  
Laboratory Results ◽  
Pleural Involvement

Objectives.To evaluate tomographic changes in pulmonary tuberculosis (TB), degree of agreement among three radiologists regarding tomographic diagnoses, and sequelae following treatment.Methods.Cross-sectional and descriptive study of 74 TB patients confirmed by sputum culture and chest computed tomography before (CT1) and 6 months after (CT2) drug therapy. Results were performed by three radiologists blinded to clinical and laboratory results.Results.Main findings in CT1 included nodules indicating the presence of a tree-in-bud pattern in 93% of cases, ill-defined nodules in 84% of cases, consolidation in 77% of cases, architectural distortion in 71% of cases, cavitary lesions in 62% of cases, and ground glass opacities in 37% of cases. Airway involvement, characterized by increased thickness and dilatation of the bronchial walls, occurred in 93% of cases. Pleural involvement occurred in 54%. There was an agreement on active TB among the three radiologists in 85% of cases. The results in CT2 indicated the presence of architectural distortion in 91% of cases and cylindrical bronchiectasis in 86%.Conclusions.The study established a tomographic pattern for diagnosis of active TB characterized by the presence of airway nodules, consolidation, architectural distortion, and cavitary lesions, and an almost complete degree of agreement (Kappa) was observed among the radiologists (0.85). CT after treatment assists in defining the cure.

scholarly journals Frequency of Pulmonary Tuberculosis on high resolution computed tomography in clinically suspected patients visiting Radiology Department Mayo Hospital, Lahore.

2019 ◽  
Vol 26 (12) ◽  
pp. 2058-2063
Author(s):  
Usman Shahid ◽  
Faiza Farooq ◽  
Khawaja Khursheed ◽  
Ishfaq Ahmad Shad ◽  
Hira Babar
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Pulmonary Tuberculosis ◽  
Descriptive Study ◽  
Low Grade ◽  
Common Symptom ◽  
Computed Tomography Scan ◽  
High Resolution Computed Tomography ◽  
Cross Sectional ◽  
Tomography Scan

High resolution computed tomography scan, in modern years, is more effective than standard computed tomography scan and conventional chest radiography in localization of diseases in the lobule of lung and in the appraisal of pulmonary parenchymal diseases because of high-resolution power and minimal partial volume effect. Objectives: To identify pulmonary tuberculosis in clinically suspected patients by high resolution computed tomography scan of chest. Study Design: Cross Sectional Descriptive study. Setting: Department of Radiology, Mayo Hospital, Lahore. Period: 15th February 2018 to 15th November 2018. Material & Methods: After taking consent, fifty patients, fulfilling inclusion and exclusion criteria, were selected by convenient sampling in this cross sectional descriptive study. Demographic details, clinical history and High resolution tomographic scan findings were documented. Data analysis was performed on Microsoft excel and statistical package for social sciences (SPSS v21) and reported by descriptive statistics. Results: Out of 50 patients, pulmonary tuberculosis was diagnosed in 44(88%) patients, acute on chronic tuberculosis in 2(4%), healed tuberculosis in 2(4%), interstitial lung disease in 1(2%) & post tubercular sequela in 1(2%) patient. Majority were males (n=29, 58%) and most patients belonged to fifth decade of life (n=19, 38%). Overall mean age of patients was 45.14±12.16 years and mostly belonged to lower socioeconomic status (n=38, 76%). Most common symptom and High resolution computed tomography finding were low grade fever in 45(95%) & consolidation in 39(78%) patients, respectively. Conclusion: High resolution computed tomography scan is valuable in diagnosis of pulmonary tuberculosis & its related spectrum of diseases in patients having clinical suspicion of pulmonary tuberculosis.

scholarly journals Undiagnosed Active Pulmonary Tuberculosis among Pilgrims during the 2015 Hajj Mass Gathering: A Prospective Cross-sectional Study

2017 ◽  
Vol 97 (5) ◽  
pp. 1304-1309 ◽  
Author(s):  
Saber Yezli ◽  
Alimuddin Zumla ◽  
Badriah Alotaibi ◽  
Abdulhafiz M. Turkistani ◽  
Yara Yassin ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Cross Sectional Study ◽  
Mass Gathering ◽  
Sectional Study ◽  
Cross Sectional ◽  
Active Pulmonary Tuberculosis

scholarly journals Chest computed tomography findings of 1271 patients with COVID-19 pneumonia and classifications with different age groups: a descriptive study from Istanbul, Turkey

2021 ◽  
Vol 67 (11) ◽  
pp. 1531-1537
Author(s):  
Safiye Sanem Dereli Bulut ◽  
Zakir Sakci ◽  
Aslihan Semiz Oysu ◽  
Fatma Kulali ◽  
Mehmet Taha Avci ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Age Groups ◽  
Descriptive Study ◽  
Chest Computed Tomography

scholarly journals 792. Number and Volume of Cavitary Lesions on Chest Computed Tomography Associated With Prolonged Time to Culture Conversion in Drug-Susceptible Pulmonary Tuberculosis

2018 ◽  
Vol 5 (suppl_1) ◽  
pp. S284-S284
Author(s):  
Alfonso Hernandez
Keyword(s):  
Computed Tomography ◽  
Pulmonary Tuberculosis ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Chest Roentgenogram ◽  
Sputum Smear ◽  
Chest Computed Tomography ◽  
Median Difference ◽  
Cox Proportional Hazards Models ◽  
Culture Conversion

Abstract Background Cavitary lesions (CLs) may be a marker of poor treatment response in pulmonary tuberculosis (PTB). Identification of CLs by chest roentgenogram (CXR) has important limitations. Chest computed tomography (CT) is more sensitive than CXR to detect CLs but the clinical relevance of CLs identified by CT remains understudied. We compared detection of CLs between CT and CXR and assessed their association with time to sputum culture conversion (tSCC). We hypothesized that increasing number and volume of CLs on CT would be associated with prolonged tSCC. Methods Retrospective cohort study of 141 culture confirmed PTB patients who underwent chest CT. We used multivariate Cox proportional hazards models to evaluate the association between chest radiological features and tSCC. Results Seventy-five (53%) patients had one or more CLs on CT. CT identified cavities in 31% of patients without a CL on CXR. Detection of cavity on CT was associated with an increased median [IQR] time to culture conversion (15 [7–35] days among noncavitary CT vs. 39 [25–55] days among cavitary CT; P < 0.0001). Among patients without CL on CXR, detection of CL on CT was associated with prolonged tSCC (median difference (CI): 16 (7–25) days, P = 0.0008). Similar results were observed among patients with 3–4+ sputum smear (median difference: 19.5 (8–31) days, P = 0.001). Adjusted Kaplan–Meier curves of number and volume of CLs and tSCC are shown in Figure 1. After confounder adjustment patients with single and multiple CL had a prolonged tSCC relative to patients without CLs on CT (adjusted Hazard Ratio [aHR] 0.56 (0.32–0.97) and 0.31 (0.16–0.60), respectively). Similarly, patients with CL volume 25 mL or more had a prolonged tSCC (aHR 0.39 (0.21–0.72)). CXR CL was not associated with prolonged tSCC. Conclusion We observed a dose–response relationship between increasing number and volume of CLs on CT and delayed tSCC independent of sputum bacillary load. Our findings highlight a role for CT in a clinical research setting to predict shorter time to culture conversion. Disclosures All authors: No reported disclosures.

scholarly journals Mathematical model and tool to explore shorter multi-drug therapy options for active pulmonary tuberculosis

2020 ◽  
Vol 16 (8) ◽  
pp. e1008107
Author(s):  
John Fors ◽  
Natasha Strydom ◽  
William S. Fox ◽  
Ron J. Keizer ◽  
Radojka M. Savic
Keyword(s):  
Mathematical Model ◽  
Drug Therapy ◽  
Pulmonary Tuberculosis ◽  
Therapy Options ◽  
Active Pulmonary Tuberculosis

scholarly journals Dual-Energy Computed Tomography Lung in patients of Pulmonary Tuberculosis

2020 ◽  
Vol 10 ◽  
pp. 39
Author(s):  
Ahmad Umar Khan ◽  
Sachin Khanduri ◽  
Zikra Tarin ◽  
Syed Zain Abbas ◽  
Mushahid Husain ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Pulmonary Tuberculosis ◽  
Imaging Techniques ◽  
Ground Glass Opacity ◽  
Signs And Symptoms ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
High Resolution Computed Tomography ◽  
Cross Sectional ◽  
Pulmonary Tb

Objectives: The objective of this study was to characterize findings of high-resolution computed tomography (HRCT) and dual-energy CT (DECT) (80 keV, 140 keV, and mixed) in pulmonary tuberculosis (TB) patients and to compare and correlate HRCT and DECT findings. Material and Methods: This cross-sectional study was conducted on 67 patients of 18–65 years of age who were suspected cases of pulmonary TB with signs and symptoms of cough, fever, hemoptysis, sputum, night sweats, and weight loss with positive sputum AFB examinations/bronchoalveolar lavage. All the patients subjected to HRCT scan and followed with DECT scan. Comparison of various imaging techniques (DECT 80 keV, DECT 140 keV, and DECT mixed) with HRCT was done for detecting lung findings and data so obtained were subjected to statistical analysis. Results: On comparing the various imaging techniques with HRCT for detecting consolidation, tree in bud pattern, cavitary lesions, ground-glass opacity, bronchiectasis, atelectasis, nodules, granuloma, peribronchial thickening, and fibrosis, the maximum agreement of HRCT was found with DECT 80 keV and minimum agreement was found with DECT 140 keV. Conclusion: The study concluded that DECT 80 keV monochromatic reconstructions among 80 keV, mixed, and 140 keV monochromatic reconstructions in lung parenchyma window settings are a faster and better analytical tool for the assessment of findings of pulmonary TB when compared with HRCT.

scholarly journals STUDI PENGARUH STATUS PERKAWINAN DAN PEKERJAAN PADA PASIEN TUBERKULOSIS DI RUMAH SAKIT DKT PURWOKERTO

2019 ◽  
Vol 10 (2) ◽  
pp. 46-51
Author(s):  
Peppy Octaviani
Keyword(s):  
Infectious Disease ◽  
Developing Countries ◽  
Pulmonary Tuberculosis ◽  
Descriptive Study ◽  
World Health ◽  
P Value ◽  
Cross Sectional ◽  
Pulmonary Tb ◽  
The World ◽  
Health Organization

ABSTRACT Pulmonary tuberculosis (TB) is a contagious pulmonary infectious disease that is still a health problem in the world, especially developing countries. Tuberculosis has been proclaimed by WHO (World Health Organization) as Global Emergency since 1992. The purpose of this study is to find out what physical characteristics are at risk of tuberculosis in DKT Hospital Purwokerto. The research design used in this study was a descriptive study with a cross-sectional approach to determine the characteristics of pulmonary TB patients who were adherent to treatment and those who did not comply with treatment at the DKT Hospital in Purwokerto. This research was conducted at the DKT Purwokerto Hospital in May 2018. The samples studied in this study were pulmonary TB patients who were obedient to treatment and non-compliance with treatment at the DKT Purwokerto Hospital for the period of 1 January - 30 December 2017 that met the sample criteria. The results of the study have no relationship between age and the results of sputum examination at the Purwokerto DKT Hospital (p value = 0.286), there is no relationship between sex with the results of sputum examination at DKT Purwokerto Hospital (p value = 0.261).                                                                                                                           Keywords: Pulmonary TBC, Characteristics, Phlegm Examination  

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