scholarly journals Visual Acuity and Size of Choroidal Neovascularization in Highly Myopic Eyes with a Dome-Shaped Macula

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Lu Wang ◽  
Bin-wu Lin ◽  
Xiao-fang Yin ◽  
Wei-lan Huang ◽  
Yi-zhi Wang ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Choroidal Neovascularization ◽  
Protective Factor ◽  
Case Series ◽  
Protective Mechanism ◽  
Fundus Fluorescein Angiography ◽  
Case Series Study ◽  
Significant Difference ◽  
Imagej Software ◽  
Series Study

Introduction. A dome-shaped macula (DSM) is an inward convexity or anterior deviation of the macular area. DSM is believed as a protective factor in maintaining visual acuity in highly myopic eyes. Objective. To investigate the correlation between best-corrected visual acuity (BCVA), choroidal neovascularization (CNV), and a dome-shaped macula (DSM) in highly myopic eyes. Methods. In this retrospective and observational case series study, BCVA tests and optical coherence tomography (OCT) were performed in a total of 472 highly myopic eyes (refractive error ≥6.5 diopters or axial length ≥26.5 mm). CNV was detected by fundus fluorescein angiography (FFA), and the CNV area was measured by ImageJ software. BCVA, central retinal thickness (CRT), and the CNV area were compared between highly myopic eyes with and without DSM. Results. The data revealed 13 eyes with DSM complicated by CNV, for an estimated prevalence of 25%. The eyes with CNV in the DSM group showed worse BCVA than those in the non-DSM group (1.59 ± 0.69 and 0.63 ± 0.64, respectively, p < 0.05 ), and the CNV area in the DSM group was larger than that in the non-DSM group (2793.91 ± 2181.24 and 1250.71 ± 1210.36 pixels, respectively, p < 0.05 ). After excluding the eyes with CNV, the DSM group had better BCVA than the non-DSM group (0.33 ± 0.17 and 0.44 ± 0.48, respectively, p < 0.05 ); however, no significant difference was observed in the CRT of eyes with CNV between the DSM group and the non-DSM group. Conclusion. These results show that DSM might be a protective mechanism for visual acuity, but its protective capability is limited. DSM eyes have better visual acuity within the protective capability. If a more powerful pathogenic factor exceeding the protective capability is present, then the eye will have more severe CNV and worse visual acuity.

scholarly journals Anatomical and Visual Effects of Implantable Phakic Contact Lens on Correction of Myopia

2022 ◽  
Author(s):  
Mahmoud Ekram ◽  
Ahmed Mohamed Kamal Elshafei ◽  
Asmaa Anwar Mohamed ◽  
Mohamed Farouk Sayed Othman Abdelkader
Keyword(s):  
Visual Acuity ◽  
Anterior Chamber ◽  
Contact Lens ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Case Series ◽  
Care Group ◽  
Case Series Study ◽  
Significant Difference ◽  
The Mean

Abstract Purpose: To evaluate the anatomical effects of implantable phakic contact lens (IPCL) (Care Group, India) on anterior segment and its visual outcomes .Patients and methods: In a prospective interventional case series study, 60 highly myopic eyes of 32 patients were subjected to IPCL implantation in the Ophthalmology Department of Minia University Hospital, Egypt from January 2019 to June 2021. All patients had complete ophthalmic examination and were followed up for 1 year. Pentacam was used for preoperative and postoperative estimation of anterior chamber depth (ACD), anterior chamber angle (ACA), anterior chamber volume (ACV) and IPCL vault in the 1st, 3rd, and 12th months. Assessment of corneal endothelium was done using specular microscope preoperatively and after 12 months. Preoperative and postoperative refraction and visual acuity were measured. Results: There was a statistically significant decrease in ACD, ACA, and ACV. There was no significant difference between preoperative and postoperative mean intraocular pressure (IOP) by the 12th month (P=0.163). The mean preoperative endothelial cell count (ECD) was significantly reduced from 2929.3±248 cells/mm2 to 2737.9±303 cells/mm2 at the 12th month (P<0.001). with a statistically highly significant improvement of mean Log Mar uncorrected visual acuity (UCVA) from 1.48±0.19 preoperatively to 0.46±0.11 by the end of follow up (P<0.001) with insignificant difference between preoperative best corrected visual acuity (BCVA) and postoperative UCVA (P=0.209). In the 12th month, the mean vault was 240±540 μm. No sight threatening complications occurred.Conclusion: Although IPCL induced anatomical changes, it was safe and effective for correction of high myopia.

scholarly journals Case-series study of hepatic echinococcal cysts in Serbia: viability of scolices, seropositivity and epidemiological characteristics

2017 ◽  
Vol 92 (2) ◽  
pp. 161-167 ◽  
Author(s):  
I. Colovic Calovski ◽  
A. Barac ◽  
Z. Golubovic ◽  
A. Karamarkovic ◽  
S. Mitrovic ◽  
...  
Keyword(s):  
Rural Areas ◽  
Case Series ◽  
Epidemiological Data ◽  
Viability Test ◽  
The Balkans ◽  
Case Series Study ◽  
Significant Difference ◽  
Balkan Region ◽  
Epidemiological Characteristics ◽  
Series Study

AbstractCystic echinococcosis (CE) is an endemic helminthic disease caused by infection with Echinococcus granulosus metacestodes. Although CE is endemic in the Balkan region, the exact epidemiology remains unknown. We conducted a case-series study with the aim of evaluating the correlation between seropositivity, socio-epidemiological data, pre-operative treatment with albendazole and viability of protoscolices in human hepatic hydatid cysts. Consecutive patients with hepatic CE underwent surgery to extract E. granulosis cysts. The viability of protoscolices was measured by their ability to absorb 0.1% eosin. Socio-epidemiological data were collected and serological testing was performed. In the present study, 38 patients (28 adults and 10 children) with hepatic CE were treated surgically. The scolex viability test was positive in 30/38 (79%) samples. All patients with non-viable cysts had seronegative results. The viability test was positive in 11/12 (91.6%) adult patients with pre-operative albendazole treatment and in 9/10 (90%) children. Statistically more patients were from an urban area compared with a rural area (65.8% vs. 15.7%). The increasing number of stray dogs shedding E. granulosus eggs in urban public areas in the Balkans might be the reason for the significant difference in the rate of infection between urban and rural areas in the present study. In addition, uncontrolled slaughtering of livestock, common in rural settlements, and feeding the infected viscera to dogs, favour the maintenance of the parasite cycle. We believe that the results of our study will encourage physicians, veterinarians and health authorities to initiate a programme to prevent and control CE in the Balkan region.

scholarly journals Regenerative Biotechnologies in Plastic Surgery: A Multicentric, Retrospective, Case-Series Study on the Use of Micro-Needling with Low-Level Light/Laser Therapy as a Hair Growth Boost in Patients Affected by Androgenetic Alopecia

2021 ◽  
Vol 12 (1) ◽  
pp. 217
Author(s):  
Pietro Gentile ◽  
Simone Garcovich ◽  
Soo-Ik Lee ◽  
Sangbum Han
Keyword(s):  
Laser Therapy ◽  
Case Series ◽  
Androgenic Alopecia ◽  
Retrospective Case ◽  
Low Level ◽  
Case Series Study ◽  
Significant Difference ◽  
Assessment Scales ◽  
Series Study

A new biotechnology based on micro-needling (MND) with low-level light/laser therapy (LLLT) that is used for hair re-growth (HR-G) needs to be standardized. The study aims to report the clinical outcomes resulting from a multicentric, retrospective, observational, case-series study in which MND with LLLT was used on patients affected by androgenic alopecia (AGA). Twenty-six patients were initially enrolled of which 15 males were classified as stages I–III of vertex by the Norwood–Hamilton scale, and 11 females was classified in stages I–II by the Ludwig scale. Twenty patients (10 females and 10 males) were analyzed after their screening (the exclusion and inclusion criteria evaluation). The HR-G assessment was evaluated with photography, as well as the physician’s and patient’s global assessment scales, in addition to standardized phototrichograms, during a short follow-up at T0-baseline, T1-16 weeks. Encouraging results represented by a hair density increase of 12 ± 2 hairs/cm2 at T1 after 16 weeks (16 weeks vs. 0 weeks) in the targeted area, compared with the baseline results (59 ± 2 hairs/cm2 at T1 versus 47 ± 2 hairs/cm2 at baseline), were observed using computerized trichograms with a statistically significant difference in hair re-growth (p = 0.0238). The effectiveness of MND with LLLT use has been demonstrated in mild to moderate AGA patients.

scholarly journals Correction of Pre-Existing Astigmatism with Phacoemulsification Using Spherical Intraocular Lens and Wave front Guided Surface Ablation: A Retrospective Case Series

2021 ◽  
pp. 24-29
Author(s):  
Ahmed El-Shehawy ◽  
Ahmed El-Massry ◽  
Mohamed El- Shorbagy ◽  
Mohamed Atef ◽  
Moataz Sabry
Keyword(s):  
Visual Acuity ◽  
Intraocular Lens ◽  
Case Series ◽  
Corneal Astigmatism ◽  
Retrospective Case ◽  
Astigmatism Correction ◽  
Surface Ablation ◽  
Retrospective Case Series ◽  
Case Series Study ◽  
Significant Difference

Objective: To evaluate safety and efficacy of using spherical intraocular lens followed by wavefront guided surface ablation in correction of preexisting regular corneal astigmatism. Methods: This retrospective case series study included 20 eyes of 16 patients having visually significant cataracts and co-existing regular corneal astigmatism. The patients underwent phacoemulsification with spherical intraocular lens and wavefront guided PRK three months later.  Results: There was a statistically significant difference for Uncorrected Visual Acuity UCVA, Best Corrected Visual Acuity BCVA, Manifest Refraction Spherical Equivalent MRSE, and refractive astigmatism postoperatively regarding all these parameters (P˂0.05). Conclusion: Astigmatism correction during or even after cataract surgery is a safe and effective method to improve visual outcomes. Longer period of follow up are required to evaluate stability of this technique and possibility of regression.

scholarly journals Role of Panretinal Photocoagulation in Improvement of Visual Acuity of Patients with Proliferative Diabetic Retinopathy

2021 ◽  
pp. 211-217
Author(s):  
Shabeer Ahmed Bhutto ◽  
Zakaullah Gopang ◽  
Safder Ali Abbasi ◽  
Naeem Akhtar Katpar ◽  
Muhammad Yusuf Depar ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Case Series ◽  
Panretinal Photocoagulation ◽  
Yag Laser ◽  
Case Series Study ◽  
Medical University ◽  
Series Study

Objective: To determine the improvement of visual acuity in patients having proliferative diabetic retinopathy undergoing panretinal photocoagulation therapy. Study design: This is a descriptive case series study. Setting: Study carried out at Ophthalmology Department, ShaheedMohtarma Benazir Bhutto Medical University Larkana, from 01-10-2019 to 31-03-2020 (06 months). Materials and methods: We selected patient with proliferative diabetic retinopathy from the retina clinic after taking a careful history and clinical examination including visual acuity anterior and posterior segment examination and then patient selected for panretinal coagulation with the  help of frequency-doubled Nd: YAG laser in three or four sittings. Results: The total of 158 eyes of 110 patients with proliferative diabetic retinopathy were included in this study out of which improvement of visual acuity was found in 38 (24%) eyes and 120 (76%) eyes have no improvement or same vision. Conclusion: Proliferative Diabetic Retinopathy (PDR) can successfully be treated with panretinal coagulation with the help of frequency doubled Nd: YAG laser therapy.

scholarly journals The Effect of Chromium in the Management of Diabetic Macular Edema: An Interventional Comparative Case Series

2021 ◽  
Vol 8 (2) ◽  
pp. 1-6
Author(s):  
Suresh K Karri ◽  
Keyword(s):  
Visual Acuity ◽  
Diabetic Retinopathy ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Proliferative Diabetic Retinopathy ◽  
Case Series ◽  
Macular Thickness ◽  
Case Series Study ◽  
Series Study

Objective of the present study was to investigate the effect of chromium polynicotinate supplementation on the visual acuity and macular thickness of the diabetic macular edema in patients with non-proliferative diabetic retinopathy through a prospective, interventional comparative case series study, was performed in 120 patients.

scholarly journals Evaluation of the consequences of early permission of mothers with cesarean delivery

2021 ◽  
Vol 8 (11) ◽  
pp. 1824
Author(s):  
Faranak Jalilvand ◽  
Maryam Sadat-Razavi ◽  
Afshan Sharghi ◽  
Zahra Ghavami ◽  
Reza Izadi
Keyword(s):  
Body Mass Index ◽  
Cesarean Section ◽  
Vital Signs ◽  
Case Series ◽  
Early Discharge ◽  
High Tendency ◽  
Case Series Study ◽  
Significant Difference ◽  
Good General Condition ◽  
Series Study

Background: In Iran, there is a high tendency to give birth by cesarean section, while about 75% of them are unnecessary and selective. In many hospitals in the country, mothers who have undergone cesarean section are permission 24 hours after the operation if they have stable vital signs and are in good general condition. The aim of this study was to evaluate the consequences of early discharge in mothers who underwent cesarean section.Methods: This descriptive case-series study was performed on 400 pregnant women aged 18-40 years with a gestational age of 37 weeks and more who were admitted to the hospital in Ardabil city for cesarean section at year 2019. Patients without any preference were divided into two groups. The first group was discharged 24 hours and second group was discharged 72 hours after surgery. Individuals in both groups were followed up by telephone 1 and 6 weeks after permission. The relevant checklist was completed for all of them. Other necessary data were collected through a questionnaire containing demographic and clinical information.Results: Two groups were matched in terms of age and body mass index. At one and six weeks after discharge; there was no significant difference between two groups in terms of fever, readmission, symptoms of infection and use of antibiotics.Conclusions: The results of the present study showed that after cesarean section, if the patient's vital signs are stable, the patient can be discharged after 24 hours.

scholarly journals Aesthetics outcome of immediately restored single implants placed in extraction sockets in the anterior maxilla: A case series study

2020 ◽  
Vol 14 (1) ◽  
pp. 48-53
Author(s):  
Amin Saedi Germi ◽  
Vadoud Ghasemi Barghi ◽  
Karim Jafari ◽  
Rahman Nemati ◽  
Saeed Yeganzad
Keyword(s):  
Soft Tissue ◽  
Case Series ◽  
T Test ◽  
Facial Soft Tissue ◽  
Anterior Maxilla ◽  
Case Series Study ◽  
Significant Difference ◽  
The Status ◽  
The Aesthetic ◽  
Series Study

Background . Immediate single implant placement and restoration (IIR) is recognized as a novel method and is the main request of many patients. This study was designed to evaluate the aesthetic outcomes of immediately restored single implants placed in extraction sockets in theanterior maxilla. Methods. In this case series study, 18 patients were selected from two private clinics after placing a single-tooth implant in the anterior maxilla. Immediate provisional crowns were delivered on the following day or at most 48 hours later, and guidelines were provided. The Pink Esthetic Score (PES) questionnaire was used at 6- and 12-month follow-ups to assess aesthetic outcomes. Data were analyzed with single t-test and dependent t-test. Results. In general, the results showed that the status of the mesial papilla, distal papilla, curve of the facial soft tissue line, level of the facial peri-implant mucosa and root convexity soft tissue in IIR method were optimal (P<0.05), with total PES means of 9.44±0.783 and 8.58±1.003 after 6 and 12 months, respectively. Also, the results showed a significant difference in PES between the 6-month and 12-month intervals (P<0.05). Conclusion. IIR is a viable method that resulted in optimal aesthetic outcomes based on PES in the short term. Considering its confirmation in this study and previous studies, it is recommended that dentists apply this method.

scholarly journals Descompresión orbitaria endoscópica transnasal en orbitopatía por enfermedad de Graves

2017 ◽  
Vol 2 (3) ◽  
pp. 25-29
Author(s):  
Martín Alonso Pinzón Navarro ◽  
Perla Villamor Rojas
Keyword(s):  
Visual Acuity ◽  
Case Series ◽  
Orbital Decompression ◽  
San Jose ◽  
Ocular Symptoms ◽  
Case Series Study ◽  
Graves Orbitopathy ◽  
Retrospective Nature ◽  
Series Study

Introducción: La orbitopatía distiroidea ocasiona un aumento del volumen orbitario, exoftalmos y síntomas oculares severos como pérdida de la agudeza visual, diplopía y compromiso del nervio óptico. Los corticoesteroides y la radioterapia han sido usados para su tratamiento pero con efectos secundarios indeseables. La cirugía se puede considerar una de las mejores opciones de manejo.Objetivo: El objetivo del estudio es describir los resultados quirúrgicos de los pacientes con orbitopatía por enfermedad de Graves sometidos a descompresión endoscópica transnasal de órbita en el Hospital de San José en Bogotá, Colombia, entre el año 2009 y 2014.Métodos: Se realizó un estudio descriptivo longitudinal de serie de casos. Se analizaron los datos con base en cambios posoperatorios de agudeza visual, campimetría y exoftalmometría, así como complicaciones posoperatorias.Resultados: Se analizaron 32 órbitas de 16 pacientes. El 83,3% de los pacientes presentaba campimetrías pre y posoperatorias normales, excepto por defectos leves secundarios a ptosis palpebral. El 87,5% presentó agudeza visual preopera- toria peor o igual a 20/50, con mejoría de la agudeza visual en el posoperatorio en el 100% de los casos. La exoftalmometría preoperatoria tuvo una mediana de 24 mm (RIQ: 21,8-27) (DS: 2,77), mientras que la posquirúrgica presentó una mediana de 1,25 mm (RIQ:16-21) (DS: 2,99), la cual se considera un estudio dentro de límites normales. La única complicación reportada fue la presencia de diplopía en 4 de los 16 pacientes (25%), de los cuales una fue transitoria y 3 persistieron durante todo el seguimiento (18,75%).Conclusiones: Existen limitaciones en el estudio al ser retrospectivo descriptivo; sin embargo, los datos obtenidos muestran a la descompresión orbitaria transnasal para orbitopatía de Graves como una intervención segura y eficaz.Abstract Introduction: Dysthyroid orbitopathy causes an increase in orbital volume, exophthalmos and severe ocular symptoms such as loss of visual acuity, diplopia, and optic nerve involvement. Corticosteroids and radiotherapy have been used for treatment but with undesirable side effects. The surgery can be considered one of the best treatment options.Objective: The aim of the study was to describe the surgical outcomes of patients with Graves’ orbitopathy, treated with transnasal endoscopic orbital decompression in Hospital de San José in Bogotá, Colombia, between 2009 and 2014. Methods: A descriptive longitudinal case series study was conducted. Data were analyzed taking into account postsurgical changes of visual acuity, exophthalmometry and campimetry, also postoperative complications. Results: 32 orbits of 16 patients were analyzed. 83.3% of patients had pre and postoperative normal campimetries except slight defects, due to palpebral ptosis. 87.5% had preoperative visual acuity worse or equal than 20/50, with improved visual acuity postoperatively in 100% of cases. The preoperative exophthalmometry 24 mm had a median (IQR 21.8-27) (SD: 2.77), while the postoperative median was 18.25 mm (IQR 16-21) (SD: 2.99), which is considered a normal study. The only complication reported was the presence of diplopia in 4 of the 16 patients (25%), of which 1 was transient and 3 persisted throughout follow-up (18.75%).Conclusions: There are limitations on the study due to its retrospective nature, but the data showed the transnasal orbital decompression for Graves orbitopathy as a safe and effective intervention.

scholarly journals Macular hole edge morphology predicts restoration of postoperative retinal microstructure and functional outcome

2020 ◽  
Author(s):  
Jiwei Tao ◽  
Huan Chen ◽  
Lin Zhu ◽  
Deming Pan ◽  
Jia Fang ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Macular Hole ◽  
Case Series ◽  
Morphological Characteristics ◽  
Final Visual Acuity ◽  
Negative Group ◽  
Visual Outcomes ◽  
Hole Edge ◽  
Case Series Study ◽  
Series Study

Abstract Background: To investigate the association between iOCT feature in macular hole (MH) surgery and the restoration of the retina microstructure and visual outcomes. Methods: This was a case series study including fifty-three eyes of 53 patients with macular hole were recruited. According to the morphological characteristics of the hole edge as imaged by iOCT after ILM peeling, all patients were divided into three groups: fovel flap group, hole-door group, and negative group. The restoration of the retina microstructure and postoperative visual outcomes of the MH surgery were compared between these groups. Results: All of the eyes had MH closure after vitrectomy. The postoperative BCVA was significantly improved compared with the preoperative BCVA (P<0.001). Based on the features of the hole edge as reveal by iOCT, the negative group included 24 eyes, the fovea flap group included 14 eyes, and the hole-door group included 15 eyes. The hole-door group and foveal flap group had significantly better final visual acuity and postoperative restoration of the ELM than the negative group (P=0.002, P=0.012). For the group in which the MHD was ≤400 μm, there were no significant differences in ELM restoration, EZ restoration, or BCVA among the three groups (P=0.516 and P=0.179 respectively). For the MHD >400-μm group, the hole-door group and fovea flap group had significantly better final visual acuity and restoration of ELM than the negative group (P=0.013, P=0.005). Conclusion: This study describes a novel intraoperative sign using iOCT. This sign can provide useful predictive information for postoperative restoration of the retinal microstructure and visual outcomes of MHs, especially large ones

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