scholarly journals Evidence according to Cochrane Systematic Reviews on Alterable Risk Factors for Anastomotic Leakage in Colorectal Surgery

2020 ◽  
Vol 2020 ◽  
pp. 1-15 ◽  
Author(s):  
Bradley Wallace ◽  
Fabia Schuepbach ◽  
Stefan Gaukel ◽  
Ahmed I. Marwan ◽  
Ralph F. Staerkle ◽  
...  

Anastomotic leakage reflects a major problem in visceral surgery, leading to increased morbidity, mortality, and costs. This review is aimed at evaluating and summarizing risk factors for colorectal anastomotic leakage. A generalized discussion first introduces risk factors beginning with nonalterable factors. Focus is then brought to alterable impact factors on colorectal anastomoses, utilizing Cochrane systematic reviews assessed via systemic literature search of the Cochrane Central Register of Controlled Trials and Medline until May 2019. Seventeen meta-anaylses covering 20 factors were identified. Thereof, 7 factors were preoperative, 10 intraoperative, and 3 postoperative. Three factors significantly reduced the incidence of anastomotic leaks: high (versus low) surgeon’s operative volume (RR=0.68), stapled (versus handsewn) ileocolic anastomosis (RR=0.41), and a diverting ostomy in anterior resection for rectal carcinoma (RR=0.32). Discussion of all alterable factors is made in the setting of the pre-, intra-, and postoperative influencers, with the only significant preoperative risk modifier being a high colorectal volume surgeon and the only significant intraoperative factors being utilizing staples in ileocolic anastomoses and a diverting ostomy in rectal anastomoses. There were no measured postoperative alterable factors affecting anastomotic integrity.

Author(s):  
Shahnam ASKARPOUR ◽  
Mehran PEYVASTEH ◽  
Hazhir JAVAHERIZADEH ◽  
Nasim ASKARI

Background: Anastomotic leak are reported among neonates who underwent esophageal atresia. Aim: To find risk factors of anastomotic leakage in patients underwent esophageal repair. Methods: All cases with esophageal atresia were included. In this case control study, patients were classified in two groups according to presence or absence of anastomotic leaks. Duration of study was 10 years. Results: Sixty-one cases were included. Mean±SD age at time of surgery in patients with leakage and without leakage was 9.50±7.25 and 8.83±6.93 respectively (p=.670). Blood transfusion and two layer anastomosis had significant correlation with anastomotic leakage. Conclusion: Blood transfusion and double layer anastomosis are associated with higher rate of anastomotic leakage.


2021 ◽  
Author(s):  
Carole Lunny ◽  
Trish Neelakant ◽  
Alyssa Chen ◽  
Gavindeep Shinger ◽  
Adrienne Stevens ◽  
...  

Abstract Background: Overviews synthesising the results of multiple systematic reviews help inform evidence-based clinical practice. In this first of two companion papers, we evaluate the bibliometrics of overviews, including their prevalence and factors affecting citation rates and journal impact factor.Methods: We searched MEDLINE, Epistemonikos and Cochrane databases. We included overviews that: (a) synthesised reviews, (b) conducted a systematic search, (c) had a methods section, and (d) examined a healthcare intervention. Multivariate regression was conducted to determine the association between citation density, impact factor and 6 predictor variables. Results: We found 1218 overviews published from 2000 to 2020; the majority (73%) were published in the most recent 5-year period. We extracted a selection of these overviews (n=541; 44%) dated from 2000 to 2018. The 541 overviews were published in 307 journals; Cochrane Database (8%), PLOS ONE (3%) and Sao Paulo Medical Journal (2%) were the most prevalent. The majority (70%) were published in journals with impact factors between 0.05 and 3.97. We found a mean citation count of 10 overviews per year, published in journals with a mean impact factor of 4.4. In multivariate analysis, overviews with a high number of citations and impact factors had more authors, larger sample sizes, were open access and reported the funding source. Conclusions: An 8-fold increase in the number of overviews was found between 2009 and 2020. We identified 332 overviews published in 2020, which is equivalent to 1 overview published per day. Overviews perform above average for the journals in which they publish.


2020 ◽  
Vol 10 ◽  
pp. 1-58
Author(s):  
Mónica Santos

Introduction/ objectives Over the last few decades getting tattoos has been progressively better accepted by society in most countries; thus, the number of establishments and professionals in the area has also increased. However, since it is a recent activity and with heterogeneous norms/ licensing, these individuals often escape the evaluation by Occupational Health. The literature on this subject is scarce. This review was intended to characterize the profession of tattoo artist with regard to: vocational training; main risk factors/ occupational risks; more prevalent semiology and associated major diseases; work accidents; collective/ individual protection measures adopted and associated legislation. Methodology This is a Scoping Review, initiated through a survey conducted in April 2019 in the databases “CINALH plus with full text, Medline with full text, Database of Abstracts of Reviews of Effects, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: Comprehensive, MedicLatina, Academic Search Ultimate, Science Direct, Web of Science, SCOPUS and RCAAP. Content In most countries, a person can work in the area without having specific qualifications; the products can be purchased via internet and the rules for opening the establishment vary locally. Given the absence of norms that parameterize the necessary qualifications to exercise, the same happens in the process of teaching in this sector. The main occupational risks/ risk factors are the quimical and biological agents, vibrations, noise, forced/ maintained postures, repetitive movements, visual effort, handling needles and sharps and prolonged shifts. Musculoskeletal semiology is very prevalent. Discussion / Conclusions / Limitations / Projects for the Future The risk factors are very similar to other professional sectors, such as dental medicine, which has already been studied in detail. Most of the few published documents on Tattoo Artists have a simplistic methodology and the samples are small. In addition, the absence of uniform labor standards and licensing undermines safe work. It would be very important that these arise and be progressively perfected. In a post-implementation phase, it would be desirable to have an institution with the capacity and authority to monitor compliance and to require the correction of identified problems. Similarly, it would also be interesting if the education process were also formalized and compulsory, perhaps starting at a technical level and evolving (if the progression of the sector allows or requires), to other degree.


2018 ◽  
Vol 43 (2) ◽  
pp. 33-41
Author(s):  
Duniel Ricardo Ortuño Borroto ◽  
Beatriz Mellado ◽  
Sebastián Prado ◽  
Juan Pablo Vargas ◽  
Gabriel Rada

Introducción: Las lesiones cervicales no cariosas son condiciones patológicas no bacterianas localizadas en el límite amelocementario de los dientes. Los principales biomateriales descritos para el tratamiento restaurador de estas lesiones son: vidrios ionómeros, vidrios ionómeros modificados con resinas, compómeros y resinas compuestas. El objetivo de este protocolo, consiste en establecer los elementos metodológicos de una revisión sistemática que evaluará el comportamiento clínico de restauraciones cervicales realizadas con estos biomateriales. Métodos: El protocolo fue diseñado, y será reportado, en línea con Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P 2015). Se realizará una búsqueda sensible en MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials y ClinicalTrials.gov, sin restricción por lenguaje o publicación, para identificar ensayos controlados aleatorizados que comparen dos o más tratamientos restauradores en lesiones cervicales no cariosas. Los desenlaces a evaluar serán la retención de las restauraciones y caries secundaria, según criterios RYGE/USPHS. Al menos dos investigadores realizarán de manera independiente la selección de los ensayos y la extracción de los datos. El riesgo de sesgo será evaluado utilizando la herramienta recomendada por la colaboración Cochrane. Si es posible, se realizará un metanálisis y los datos serán presentados en tablas de resúmenes de resultados mediante el método Grading of Recommendations Assesment, Development and Evaluation (GRADE). Fortalezas y debilidades: Esta revisión sistemática entregará evidencia actualizada sobre el comportamiento de cuatro biomateriales en el tratamiento de lesiones cervicales no cariosas. La principal limitación proviene de la baja cantidad o deficiencias metodológicas de los estudios primarios. Número de registro (PROSPERO): CRD42017071114.


2020 ◽  
Author(s):  
Paula Enes de Oliveira ◽  
Carlos Sequeira ◽  
Núria Albacar Riobocó ◽  
Francisco Miguel Correia Sampaio

Introduction – Addictive behavior can be defined by a person's compulsion to engage in a continuous activity or behavior, despite the negative impact on their ability to remain mentally and/or physically healthy and functional in the home and community. The person may find the behavior rewarding psychologically and be satisfied while involved in the activity, but later he may feel guilt, remorseful or even be overwhelmed by the consequences of this choice on an ongoing basis1. Addressing this complexity requires multidisciplinary approaches and a range of responses and devices that, articulately and congruently, act in the various aspects of this phenomenon.Objective – This review aims to map programs or interventions in a community context with an impact on the cessation / reduction of addictive behaviors in adults, as well as to identify the characteristics of the participants and the contexts of implementation.Inclusion criteria – Will be considered published and unpublished primary and secondary studies on programs/interventions with an impact on the cessation/reduction of addictive tolls in adults between 18 and 40 years of age in community context, written in Portuguese, Spanish, or English, between 2013 and 2019.Methods – The Scoping Review will be carried out in accordance with the guidelines of the Joanna Briggs Institute and PRISMA-ScR. From the objective and research questions, the databases and research repositories will be selected, CINAHL Plus with full text (via EBSCO) and MEDLINE with full text (via PubMed), SciELO, Scopus JBI Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, and Cochrane Systematic Reviews and Scientific Repositories; OpenGrey (European repository) and Open Access Scientific Repository of Portugal (Portuguese repository) using all pre-defined Boolean keywords, terms and expressions, to identify studies with inclusion criteria. Duplicate documents will be deleted. The selection of articles will be made by two reviewers independently by reading the title, abstract and full text. The extraction and synthesis of the data will also be performed by two reviewers independently through the analysis grid previously created for this purpose, based on the model of the Joanna Briggs Institute. The data synthesis will be presented in a narrative and table format.


2020 ◽  
Author(s):  
Paula Enes de Oliveira ◽  
Carlos Sequeira ◽  
Núria Albacar Riobocó ◽  
Francisco Miguel Correia Sampaio

Introduction – Addictive behavior can be defined by a person's compulsion to engage in a continuous activity or behavior, despite the negative impact on their ability to remain mentally and/or physically healthy and functional in the home and community. The person may find the behavior rewarding psychologically and be satisfied while involved in the activity, but later he may feel guilt, remorseful or even be overwhelmed by the consequences of this choice on an ongoing basis1. Addressing this complexity requires multidisciplinary approaches and a range of responses and devices that, articulately and congruently, act in the various aspects of this phenomenon.Objective – This review aims to map programs or interventions in a community context with an impact on the cessation / reduction of addictive behaviors in adults, as well as to identify the characteristics of the participants and the contexts of implementation.Inclusion criteria – Will be considered published and unpublished primary and secondary studies on programs/interventions with an impact on the cessation/reduction of addictive tolls in adults between 18 and 40 years of age in community context, written in Portuguese, Spanish, or English, between 2013 and 2019.Methods – The Scoping Review will be carried out in accordance with the guidelines of the Joanna Briggs Institute and PRISMA-ScR. From the objective and research questions, the databases and research repositories will be selected, CINAHL Plus with full text (via EBSCO) and MEDLINE with full text (via PubMed), SciELO, Scopus JBI Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, and Cochrane Systematic Reviews and Scientific Repositories; OpenGrey (European repository) and Open Access Scientific Repository of Portugal (Portuguese repository) using all pre-defined Boolean keywords, terms and expressions, to identify studies with inclusion criteria. Duplicate documents will be deleted. The selection of articles will be made by two reviewers independently by reading the title, abstract and full text. The extraction and synthesis of the data will also be performed by two reviewers independently through the analysis grid previously created for this purpose, based on the model of the Joanna Briggs Institute. The data synthesis will be presented in a narrative and table format.


2018 ◽  
Vol 3 ◽  
pp. 117
Author(s):  
Anna Aryee ◽  
Suvi Härmälä ◽  
Laura Shallcross ◽  
Andrew Hayward

Introduction: Rates of community-acquired Escherichia coli bacteraemia (ECB) have been consistently rising. As rates of antimicrobial resistance (AMR), particularly in Gram-negative bacteria, are also increasing, this is of concern both for management of individual patients and healthcare systems. There is currently little data on the risk factors for development of community-acquired ECB: this review aims to identify these risk factors in order to inform community interventions to reduce ECB as well as antibiotic prescribing policy. Methods and analysis: We will search Medline (Ovid), Embase (Ovid), Web of Science/Scopus and the Cochrane Central Register of Controlled Trials for published reports on observational and experimental primary research studies involving patients admitted to hospital with community-acquired ECB. Two reviewers will independently screen the studies for eligibility, perform data collection and assess study quality and risk of bias. Random effects meta-analyses will be performed if appropriate. Ethics and dissemination: No primary data will be collected for this study and so formal ethical approval is not required. We will publish the results of our review in relevant peer-reviewed medical journals, and will also seek to present them at relevant medical conferences. PROSPERO registration number: CRD42018104402


2020 ◽  
Vol 9 ◽  
pp. S137-S148
Author(s):  
Mónica Santos ◽  
Armando Almeida ◽  
Catarina Lopes ◽  
Tiago Oliveira

Introduction / framework / objectives Vibrations and noise are two reasonably prevalent occupational risk factors and, in many situations, present together. If a pathophysiological association between them is real, it will be very relevant to verify this, in order to readjust, if necessary, the vibration and noise limits considered safe. Methodology This is an Scoping Review, initiated by a September 2019 survey of the “Cochrane Central Register of Controlled Trials databases, CINALH plus with full text, Database of Abstracts of Reviews of Effects, Cochrane Database of Systematic Reviews, Cochrane Methodology Register, Nursing and Allied Health Collection: Comprehensive, MedicLatina, Academic Search Ultimate, Science Direct, SCOPUS and RCAAP.” Content Some researchers have quantified higher hearing losses in workers simultaneously exposed to noise and vibrations; however, workers exposed to vibration from work instruments are generally also exposed to higher levels of noise. If there is a pathophysiological link between these two occupational risk factors, it is believed that this may be related to the theory of sympathetic vasoconstriction (observed in white-finger syndrome) and may also damage the cochlea, producing ischemic damage to the hair cells. Another hypothesis points out that some work tools may give rise to vibrations that can reach the inner ear directly, through bone conduction (especially at the temporal level). Conclusions Most of the studies consulted did not have a very robust methodology that allows a rigorous evaluation of whether the most intense hypoacusis in individuals simultaneously exposed to vibration results from a true pathophysiological association, or if it is only a statistical bias. It would be interesting for occupational health teams to investigate on clients with workers simultaneously exposed to these two risk factors (and, if possible, with combinations of different intensities), in order to produce knowledge capable of enhancing occupational health and safety.


2016 ◽  
Vol 5 ◽  
Author(s):  
Rahel L. Birru ◽  
Vasudha Ahuja ◽  
Abhishek Vishnu ◽  
Rhobert W. Evans ◽  
Yoshihiro Miyamoto ◽  
...  

AbstractRecent studies suggest that the ability to produce equol, a metabolite of the soya isoflavone daidzein, is beneficial to coronary health. Equol, generated by bacterial action on isoflavones in the human gut, is biologically more potent than dietary sources of isoflavones. Not all humans are equol producers. We investigated whether equol-producing status is favourably associated with risk factors for CHD following an intervention by dietary soya isoflavones. We systematically reviewed randomised controlled trials (RCT) that evaluated the effect of soya isoflavones on risk factors for CHD and that reported equol-producing status. We searched PubMed, EMBASE, Ovid Medline and the Cochrane Central Register for Controlled Trials published up to April 2015 and hand-searched bibliographies to identify the RCT. Characteristics of participants and outcomes measurements were extracted and qualitatively analysed. From a total of 1671 studies, we identified forty-two articles that satisfied our search criteria. The effects of equol on risk factors for CHD were mainly based on secondary analyses in these studies, thus with inadequate statistical power. Although fourteen out of the forty-two studies found that equol production after a soya isoflavone intervention significantly improved a range of risk factors including cholesterol and other lipids, inflammation and blood pressure variables, these results need further verification by sufficiently powered studies. The other twenty-eight studies primarily reported null results. RCT of equol, which has recently become available as a dietary supplement, on CHD and its risk factors are awaited.


2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Soheil Hassanipour ◽  
Mojtaba Sepandi ◽  
Reza Tavakkol ◽  
Mousa Jabbari ◽  
Hadiseh Rabiei ◽  
...  

Abstract Background Occupational contact with blood and body fluids poses a significant risk to healthcare workers. The aim of this systematic review is to investigate the epidemiology and risk factors affecting needlestick injuries (NSI) in healthcare personnel in Iran. Methods In March 2020, researchers studied six international databases such as Medline/PubMed, ProQuest, ISI/WOS, Scopus, Embase, and Google Scholar for English papers and two Iranian databases (MagIran and SID) for Persian papers. Joanna Briggs Institute (JBI) Critical Appraisal Checklist was used to assess quality of studies. The method of reporting was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement. Results A total of 43 articles were included in the analysis. Results showed that females (OR = 1.30, 95 % CI 1.06–1.58, P value = 0.009), younger age (OR = 2.75, 95 % CI 2.27–3.33, P value < 0.001, rotated shift workers (OR = 2.16, 95 % CI 1.47–3.15, P value < 0.001), not attending training courses (OR = 1.30, 95 % CI 1.07–1.56, P value = 0.006), working in the surgery ward (OR = 1.83, 95 % CI 1.33–2.50, P value < 0.001), less work experience (OR = 1.43, 95 % CI 1.04–1.95, P value = 0.025) apposed a greater risk factors for NSI among healthcare workers. Conclusion Based on the results of this review, factors such as young age, less work experience, work shift, and female gender are considered as strong risk factors for NSI injury in Iran. Preventive measures including education programs can reduce the burden of NSI among healthcare personnel.


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