scholarly journals Determinants of Resting Oxidative Stress in Middle-Aged and Elderly Men and Women: WASEDA’S Health Study

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Takuji Kawamura ◽  
Kumpei Tanisawa ◽  
Ryoko Kawakami ◽  
Chiyoko Usui ◽  
Tomoko Ito ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Physical Fitness ◽  
Regression Model ◽  
Biochemical Parameters ◽  
Nutritional Intake ◽  
Middle Aged ◽  
Elderly Men ◽  
Men And Women ◽  
Leg Extension ◽  
Objectively Measured

Previous studies have not investigated the determinants of resting oxidative stress, including physical fitness, as it relates to redox regulation. The present study therefore was aimed at identifying lifestyle and biological factors that determine resting oxidative stress, including objectively measured physical fitness. In 873 middle-aged and elderly men and women, age and anthropometric parameters, lifestyle-related parameters, medication and supplementation status, physical fitness, biochemical parameters, and nutritional intake status, as well as three plasma oxidative stress markers: protein carbonyl (PC), F2-isoprostane (F2-IsoP), and thiobarbituric acid reactive substances (TBARS), were surveyed and measured. The determinants of PC, F2-IsoP, and TBARS in all participants were investigated using stepwise multiple regression analysis. In PC, age ( β = − 0.11 , P = 0.002 ), leg extension power ( β = − 0.12 , P = 0.008 ), BMI ( β = 0.12 , P = 0.004 ), and HDL-C ( β = 0.08 , P = 0.040 ) were included in the regression model (adjusted R 2 = 0.018 ). In the F2-IsoP, smoking status ( β = 0.07 , P = 0.060 ), BMI ( β = 0.07 , P = 0.054 ), and HbA1c ( β = − 0.06 , P = 0.089 ) were included in the regression model (adjusted R 2 = 0.006 ). In TBARS, glucose ( β = 0.18 , P < 0.001 ), CRF ( β = 0.16 , P < 0.001 ), age ( β = 0.15 , P < 0.001 ), TG ( β = 0.11 , P = 0.001 ), antioxidant supplementation ( β = 0.10 , P = 0.002 ), and HbA1c ( β = − 0.13 , P = 0.004 ) were included in the regression model (adjusted R 2 = 0.071 ). In conclusion, the present study showed that age, anthropometric index, lifestyle-related parameters, medication and supplementation status, objectively measured physical fitness, biochemical parameters, and nutritional intake status explain less than 10% of oxidative stress at rest.

scholarly journals RELATIONSHIP OF HEALTH AND PHYSICAL FITNESS IN MIDDLE-AGED AND ELDERLY MEN AND WOMEN

1996 ◽  
Vol 45 (2) ◽  
pp. 357-363 ◽  
Author(s):  
TOSHIRO SATO ◽  
TOMOHIKO MURASE ◽  
TERUAKI FUJII ◽  
SATOSHI IWAO ◽  
YOSHIKI KOBAYASHI ◽  
...  
Keyword(s):  
Physical Fitness ◽  
Middle Aged ◽  
Elderly Men ◽  
Men And Women ◽  
Relationship Of

scholarly journals SOME APPEARANCE ON THE PHYSICAL FITNESS AND PHYSIQUE OF MIDDLE AGED MEN AND WOMEN WHO LIVE IN TOKYO

1969 ◽  
Vol 18 (3-4) ◽  
pp. 53-71
Author(s):  
Mitsutsugu Ono ◽  
Yoshiro Morishita ◽  
Naomichi Yamamoto ◽  
Reizo Ishii
Keyword(s):  
Physical Fitness ◽  
Middle Aged ◽  
Men And Women

scholarly journals Association of metabolic syndrome and oxidative stress with ischemic heart disease in middle-aged persons

Medicina ◽  
2008 ◽  
Vol 44 (5) ◽  
pp. 392 ◽  
Author(s):  
Liucija Černiauskienė ◽  
Dalia Lukšienė ◽  
Abdonas Tamošiūnas ◽  
Regina Rėklaitienė ◽  
Lilija Margevičienė
Keyword(s):  
Oxidative Stress ◽  
Metabolic Syndrome ◽  
Heart Disease ◽  
Vitamin E ◽  
Ischemic Heart Disease ◽  
Odds Ratio ◽  
Ischemic Heart ◽  
Middle Aged ◽  
Men And Women ◽  
And Oxidative Stress

The aim of this study was to evaluate the association of metabolic syndrome and oxidative stress with ischemic heart disease in middle-aged persons (men and women aged 45–64 years). Material and methods. In this study, we have used data of 533 persons (247 men and 286 women) aged 45– 64 years from Kaunas population cohort investigated according to WHO MONICA study protocol during 2001–2002 in whom concentrations of malondialdehyde, a marker of lipid peroxidation, and antioxidant vitamin E in blood serum were determined. Metabolic syndrome was defined by the criteria of Adult Treatment Panel III. Oxidative stress was determined in the presence of increased level of malondialdehyde (≥5 mmol/L) and decreased level of lipid-standardized vitamin E (<20 mmol/L). The levels of malondialdehyde and vitamin E were measured by fluorimetric methods. Results. Ischemic heart disease was diagnosed in 19.8% of men and 21.3% of women. The frequency of ischemic heart disease among persons (men and women) with metabolic syndrome was significantly higher than among persons without metabolic syndrome (27.4% vs. 17.8%, respectively; odds ratio, 1.63; P=0.032). The frequency of ischemic heart disease among persons with oxidative stress was significantly higher than among persons without oxidative stress (29.1% vs. 17.6%, respectively; odds ratio, 1.88; P=0.029). The highest prevalence of ischemic heart disease (30.0%) was among persons with metabolic syndrome and oxidative stress, and the lowest prevalence of this disease (13.8%) was among persons without metabolic syndrome and without oxidative stress (odds ratio, 2.54; P=0.017). These data were adjusted by sex and age. Conclusion. Metabolic syndrome and oxidative stress are significantly associated with ischemic heart disease among 45–64-year-old persons.

scholarly journals Stroke Mortality Trends in the Population of Klaipėda From 1994 to 2008

Medicina ◽  
2011 ◽  
Vol 47 (9) ◽  
pp. 512 ◽  
Author(s):  
Henrikas Kazlauskas ◽  
Nijolė Raškauskienė ◽  
Rima Radžiuvienė ◽  
Vinsas Janušonis
Keyword(s):  
Mortality Rate ◽  
Mortality Rates ◽  
Mortality Data ◽  
World Population ◽  
Stroke Mortality ◽  
Middle Aged ◽  
Elderly Men ◽  
Men And Women ◽  
Specific Mortality ◽  
Permanent Residents

The objective of the study was to evaluate the trends in stroke mortality in the population of Klaipėda aged 35–79 years from 1994 to 2008. Material and Methods. Mortality data on all permanent residents of Klaipėda aged 35–79 years who died from stroke in 1994–2008 were gathered for the study. All death certificates of permanent residents of Klaipėda aged 35–79 years who died during 1994–2008 were examined in this study. The International Classification of Diseases (ICD-9 codes 430–436, and ICD-10 codes I60–I64) was used. Sex-specific mortality rates were standardized according to the Segi’s world population; all the mortality rates were calculated per 100 000 population per year. Trends in stroke mortality were estimated using log-linear regression models. Sex-specific mortality rates and trends were calculated for 3 age groups (35–79, 35–64, and 65–79 years). Results. During the entire study period (1994–2008), a marked decline in stroke mortality with a clear slowdown after 2002 was observed. The average annual percent changes in mortality rates for men and women aged 35–79 years were –4.6% (P=0.041) and –6.5% (P=0.002), respectively. From 1994 to 2002, the stroke mortality rate decreased consistently among both Klaipėda men and women aged 35–64 years (20.4% per year, P=0.002, and 14.7% per year, P=0.006, respectively) and in the elderly population aged 65–79 years (13.8% per year, P=0.005; and 12% per year, P=0.019). During 2003–2008, stroke mortality increased by 16.3% per year in middle-aged men (35–64 years), whereas among women (aged 35–64 and 65–79 years) and elderly men (aged 65–79 years), the age-adjusted mortality rate remained relatively unchanged. Conclusions. Among both men and women, the mortality rates from stroke sharply declined between 1994 and 2008 with a clear slowdown in the decline after 2002. Stroke mortality increased significantly among middle-aged men from 2003, while it remained without significant changes among women of the same age and both elderly men and women.

scholarly journals Hip Circumference and the Risk of Type 2 Diabetes in Middle-Aged and Elderly Men and Women: The Shanghai Women and Shanghai Men’s Health Studies

2011 ◽  
Vol 21 (5) ◽  
pp. 358-366 ◽  
Author(s):  
Baqiyyah Conway ◽  
Yong-Bing Xiang ◽  
Raquel Villegas ◽  
Xianglan Zhang ◽  
Honglan Li ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Men’S Health ◽  
Men's Health ◽  
Middle Aged ◽  
Hip Circumference ◽  
Elderly Men ◽  
Men And Women ◽  
Health Studies

scholarly journals Resting, night-time, and 24 h heart rate as markers of cardiovascular risk in middle-aged and elderly men and women with no apparent heart disease

2013 ◽  
Vol 34 (23) ◽  
pp. 1732-1739 ◽  
Author(s):  
C. D. Johansen ◽  
R. H. Olsen ◽  
L. R. Pedersen ◽  
P. Kumarathurai ◽  
M. R. Mouridsen ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Middle Aged ◽  
Elderly Men ◽  
Night Time ◽  
Men And Women

scholarly journals Dietary patterns, food groups, and nutrients as predictors of plasma choline and betaine in middle-aged and elderly men and women

2008 ◽  
Vol 88 (6) ◽  
pp. 1663-1669 ◽  
Author(s):  
Svetlana V Konstantinova ◽  
Grethe S Tell ◽  
Stein E Vollset ◽  
Arve Ulvik ◽  
Christian A Drevon ◽  
...  
Keyword(s):  
Dietary Patterns ◽  
Food Groups ◽  
Middle Aged ◽  
Elderly Men ◽  
Men And Women

scholarly journals Relationship Between Physical Fitness, BMI, WHR and Hypertension in Elderly Men and Women

2013 ◽  
Vol 52 (4) ◽  
pp. 275-284
Author(s):  
Saša Pantelić ◽  
Radmila Kostić ◽  
Ratomir Djurašković ◽  
Slavoljub Uzunović ◽  
Zoran Milanović ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Physical Fitness ◽  
Body Mass ◽  
Elderly Women ◽  
Upper Body ◽  
Predictor Variables ◽  
Elderly Men ◽  
Men And Women ◽  
Arterial Blood

Abstract Aim: The aim of this study was to determine the structure, characteristics and significance of the relationship between physical fitness, BMI and WHR on one hand and hypertension of elderly men and women on the other. Methods: The sample consisted of 1288 participants (594 men and 694 women) who live in their own households in the cities and villages of Central, Eastern and South Serbia. After the obtained classification of participants based on arterial blood pressure, 231 patients with hypertension aged 60-80 years were selected. The subsample consisted of 138 male participants, while the subsample of women was 93 participants. Predictor variables consisted of 6 variables for the evaluation of physical fitness, Body mass index (BMI) and Waist-to Hip Ratio index (WHR). Criterion variables consisted of systolic blood pressure (SBP) and diastolic blood pressure (DBP). Results: The results showed that there is a statistically significant correlation (p <0.05) between predictor variables and hypertension. Higher values of higher SBP in elderly men causes an increase in body weight due to increased body fat (BMI, WHR). In elderly women, these changes occur under the influence of increased body mass index and reduced CRF. Higher values of high DBP in elderly men cause more power and flexibility of the upper body and in elderly women greater strength in the arms and less strength in legs and CRF. Conclusions: Being overweight in both subsamples could be considered as a factor that contributes to high blood pressure.

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