scholarly journals The Current State of Parkinsonism in West Africa: A Systematic Review

2021 ◽  
Vol 2021 ◽  
pp. 1-16
Author(s):  
Jude T. Quarshie ◽  
Esther N. Mensah ◽  
Osbourne Quaye ◽  
Anastasia R. Aikins

Parkinsonism is one of the most common neurodegenerative diseases among the elderly. Africa is experiencing an increasing burden of age-related conditions including parkinsonism. However, there is not enough data on the prevalence, symptoms, and management of the disorder in West African patients. This systematic review examines the current state of parkinsonism in West Africa by discussing its epidemiology, symptomatology, and treatment. We searched PubMed, BioMed Central, and AJOL databases from January 2000 to December 2020 for studies on parkinsonism conducted in West African countries. We included 32 studies in this review: 23 from Nigeria, 5 from Ghana, and 1 each from Benin, Mali, Niger, and Senegal. Out of the 32 reviewed studies, 11 focused on the prevalence of parkinsonism, 4 examined the genetics of Parkinson’s disease (PD), and 17 described the symptomatology and therapy of parkinsonism. The prevalence of parkinsonism in West Africa ranges from 6.0% to 8.3% of neurologic admissions/consultations. The estimated crude prevalence of PD in West Africa varies from 15 to 572 per 100,000 people. Thus far, no pathogenic genetic variants have been associated with PD in the region. Levodopa is frequently used singly or in combination with other medications to manage parkinsonian symptoms, which is consistent with reports from other African regions. Most of the reviewed studies focused only on PD, limiting assessment of other forms of parkinsonism. Almost all the prevalence studies were hospital-based and monocentric, making it impossible to accurately estimate the true prevalence of parkinsonism in West Africa. Larger community-based prevalence studies are recommended to enable accurate quantification of disease burden. Future genetic investigations should consider a wider array of gene mutations associated with parkinsonism. Moreover, public health surveillance strategies should be established to monitor the epidemiology of the disorder.

Author(s):  
Jeffrey Herbst

This chapter examines the politics of the currency in West Africa from the beginning of the twentieth century. A public series of debates over the nature of the currency occurred in West Africa during both the colonial and independence periods. Since 1983, West African countries have been pioneers in Africa in developing new strategies to combat overvaluation of the currency and reduce the control of government over the currency supply. The chapter charts the evolution of West African currencies as boundaries and explores their relationship to state consolidation. It shows that leaders in African capitals managed to make the units they ruled increasingly distinct from the international and regional economies, but the greater salience of the currency did not end up promoting state consolidation. Rather, winning the ability to determine the value of the currency led to a series of disastrous decisions that severely weakened the states themselves.


Zootaxa ◽  
2018 ◽  
Vol 4504 (2) ◽  
pp. 151 ◽  
Author(s):  
MATTHEW H. SHIRLEY ◽  
AMANDA N. CARR ◽  
JENNIFER H. NESTLER ◽  
KENT A. VLIET ◽  
CHRISTOPHER A. BROCHU

Molecular and morphological evidence has shown that the African slender-snouted, or sharp-nosed, crocodile Mecistops cataphractus (Cuvier, 1824) is comprised of two superficially cryptic species: one endemic to West Africa and the other endemic to Central Africa. Our ability to characterize the two species is compromised by the complicated taxonomic history of the lineage and overlapping ranges of variation in distinguishing morphological features. The name M. cataphractus was evidently originally based on West African material, but the holotype is now lost. Although types exist for other names based on the West African form, the name M. cataphractus is sufficiently entrenched in the literature, and other names sufficiently obscure, to justify retypification. Here, we designate a neotype for M. cataphractus and restrict it to West Africa. We resurrect M. leptorhynchus as a valid species from Central Africa and identify exemplary referred specimens that, collectively, overcome the obscurity and diagnostic limits of the extant holotype. We additionally indicate suitable neotype material in the event the holotype is lost, destroyed, or otherwise needing replacement, and we rectify the previously erroneous type locality designation. We provide a revised diagnosis for crown Mecistops, and revise and update previous descriptions of the two living species, including providing both more complete descriptions and discussion of diagnostic characters. Finally, we provide considerable discussion of the current state of knowledge of these species’ ecology, natural history, and distribution. 


2017 ◽  
Vol 41 (1) ◽  
pp. 279-310 ◽  
Author(s):  
Vaughn W. M. Watson ◽  
Michelle G. Knight-Manuel

Given polarizing popular-media narratives of immigrant youth from West African countries, we construct an interdisciplinary framework engaging a Sankofan approach to analyze education research literature on social processes of navigating identities and engaging civically across immigrant youth’s heritage practices and Indigenous knowledges. In examining social processes, we disrupt three areas of inequalities affecting educational experiences of immigrant youth: (a) homogenizing notions of a monolithic West Africa and immigrant youth’s West African countries, (b) deficit understandings of identities and the heterogeneity of Black immigrant youth from West African countries living in the United States, and (c) singular views of youth’s civic engagement. We provide implications for researchers, policymakers, and educators to better meet youth’s teaching and learning needs.


2016 ◽  
Vol 10 (02) ◽  
pp. 190-194 ◽  
Author(s):  
Arben Ndreu ◽  
Diana Hajdari ◽  
Anduena Ndoni ◽  
Klodiana Shkurti ◽  
Dhimiter Kraja ◽  
...  

This is a case-report of two patients with cerebral malaria (CM) imported from West-African countries. Notably, this form of malaria was developed as a second disease episode, while the first episode was experienced in West Africa. These findings suggest that the second episode of malaria was caused by a different strain of Plasmodium falciparum as compared to the first one. They are the first cerebral malaria cases imported in Albania after the eradication and absence of Plasmodium for five decades. Early treatment of cerebral malaria is decisive on the duration of coma and disease’s outcome.


Author(s):  
Ulrike Gut

This chapter describes the history, role, and structural properties of English in the West African countries the Gambia, Sierra Leone, Liberia, Ghana, Nigeria, the anglophone part of Cameroon, and the island of Saint Helena. It provides an overview of the historical phases of trading contact, British colonization and missionary activities and describes the current role of English in these multilingual countries. Further, it outlines the commonalities and differences in the vocabulary, phonology, morphology, and syntax of the varieties of English spoken in anglophone West Africa. It shows that Liberian Settler English and Saint Helenian English have distinct phonological and morphosyntactic features compared to the other West African Englishes. While some phonological areal features shared by several West African Englishes can be identified, an areal profile does not seem to exist on the level of morphosyntax.


Significance While the overall number of incidents is fewer than a dozen since the rise of the region's jihadist insurgencies in the early 2010s, the trend lends credence to growing warnings about the jihadist threat to coastal West African countries. Concern has focused on Ivory Coast and Benin, but there is also nervousness about Ghana, Togo and even Senegal. Impacts Western governments will boost security assistance to coastal states. Intelligence sharing and joint operations will not forestall cross-border hit-and-run attacks. Most regional states will resort to security-focused responses whose abuses drive jihadist recruitment.


1993 ◽  
Vol 18 (4) ◽  
pp. 331-358 ◽  
Author(s):  
Timothy J. Doherty ◽  
Anthony A. Vandervoort ◽  
William F. Brown

This review briefly summarizes the current state of knowledge regarding age related changes in skeletal muscle, followed by a more in-depth review of ageing effects on animal and human motor units (MUs). Ageing in humans is generally associated with reductions in muscle mass (atrophy), leading to reduced voluntary and electrically evoked contractile strength by the 7th decade for most muscle groups studied. As well, contraction and one-half relaxation times are typically prolonged in muscles of the elderly. Evidence from animal and human studies points toward age associated MU loss as the primary mechanism for muscle atrophy, and such losses may be greatest among the largest and fastest MUs. However, based on studies in animals and humans, it appears that at least some of the surviving MUs are able to partially compensate for MU losses, as indicated by an increase in the average MU size with age. The fact that muscles in the elderly have fewer, but on average larger and slower, MUs has important implications for motor control and function in this population. Key words: skeletal muscle, motor neuron, motor axon, contractile properties, adaptation


1971 ◽  
Vol 9 (4) ◽  
pp. 543-559 ◽  
Author(s):  
'Ladipo Adamolekun

While independence in West Africa focused academic attention on political parties, the proliferation of military régimes in the late 1960s– by 1970, seven West African countries had experienced military rule — brought two other institutions into prominence: the military and civil bureaucracies. This article seeks to throw some light on the place of the civil bureaucracy in Senegal through a study of the role of bureaucrats in the country's political process.


2016 ◽  
Vol 12 (31) ◽  
pp. 241
Author(s):  
Olabode Philip Olofin

This paper examines empirically the interaction among per capita income growth, climate change and food security in fifteen West African Countries. We employ Panel VAR (PVAR) techniques on annual secondary data obtained from the World Development Indicator (WDI) between 1990 and 2013. The PVAR approach allows us to address the endogeneity problem by allowing the endogenous interaction among the variables in the system. Our results provide evidence of income growth spurring food security in the short run and reducing it in the long run, while climate change increased food insecurity throughout in West Africa. The study suggests that climate change is a necessary variable that needs to be controlled if food security is a desired goal in West Africa and that more priority should be given to agricultural sector in economic growth. Also, the leaders in West Africa should embrace a judicious and dynamic energy mix that will allow renewable sources to replace fossil fuels.


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