Abstract 1766: Effect of soy isoflavones on prostate cancer cell cycle regulation and apoptosis

2010 ◽  
Author(s):  
Peter J. Van Veldhuizen ◽  
Anup Kasi Loknath Kumar ◽  
Snigdha Banerjee ◽  
Gophal Dhar ◽  
Smita Mehta ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Cycle ◽  
Cancer Cell ◽  
Cell Cycle Regulation ◽  
Prostate Cancer Cell ◽  
Soy Isoflavones ◽  
Cycle Regulation

The Tumor Suppressor Gene PTEN Plays a Role in Cell Cycle Regulation and Apoptosis in Prostate Cancer Cell Lines

2006 ◽  
pp. 487-493
Author(s):  
Alice Hlobilková ◽  
Michaela Šváchová ◽  
Jana Knillová ◽  
Eva Pimrová ◽  
Petra Řiháková ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Cycle ◽  
Tumor Suppressor ◽  
Tumor Suppressor Gene ◽  
Cell Lines ◽  
Cancer Cell ◽  
Cell Cycle Regulation ◽  
Suppressor Gene ◽  
Prostate Cancer Cell Lines ◽  
Cycle Regulation

Investigation of the synergistic effects of paclitaxel and herbal substances and endemic plant extracts on cell cycle and apoptosis signal pathways in prostate cancer cell lines

Gene ◽  
2019 ◽  
Vol 687 ◽  
pp. 261-271 ◽  
Author(s):  
Zeynep Özlem Doğan Şiğva ◽  
Tuğçe Balci Okcanoğlu ◽  
Çığır Biray Avci ◽  
Sunde Yilmaz Süslüer ◽  
Çağla Kayabaşi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Cycle ◽  
Cell Lines ◽  
Cancer Cell ◽  
Plant Extracts ◽  
Prostate Cancer Cell ◽  
Synergistic Effects ◽  
Signal Pathways ◽  
Endemic Plant ◽  
Prostate Cancer Cell Lines

Cell cycle perturbations and radiosensitization effects in a human prostate cancer cell line

2003 ◽  
Vol 129 (3) ◽  
pp. 175-182 ◽  
Author(s):  
Albert A. Geldof ◽  
Marian A.B.D. Plaizier ◽  
Ilse Duivenvoorden ◽  
Marieke Ringelberg ◽  
Richard T. Versteegh ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Cycle ◽  
Cell Line ◽  
Cancer Cell ◽  
Prostate Cancer Cell ◽  
Cancer Cell Line ◽  
Prostate Cancer Cell Line ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Human Prostate Cancer Cell

scholarly journals Combination of axitinib and dasatinib for anti-cancer activities in two prostate cancer cell lines

2015 ◽  
Vol 11 (1) ◽  
pp. 130
Author(s):  
Nai-Xiong Peng ◽  
Chun-Xiao Liu ◽  
Xi-Sheng Wang ◽  
Ze-Jian Zhang ◽  
Su-Cai Liao
Keyword(s):  
Prostate Cancer ◽  
Cell Cycle ◽  
Survival Rate ◽  
Cell Lines ◽  
Cancer Cell ◽  
Prostate Cancer Cell ◽  
Cancer Cell Lines ◽  
Prostate Cancer Cell Lines ◽  
Expression Levels ◽  
Different Response

<p class="Abstract">Prostate cancer is major cause of cancer related deaths worldwide in men. There are new treatment methods and drugs are being developed with promising results in two of the prostate cancer cell lines (PPC-1 and TSU-Pr1). These two cells were treated with 20 uM of axitinib combined with dasatinib for 6-72 hours. The cell viability assessed by the cytotoxicity assay. Various regulatory genes such as c-KIT, cell cycle and apoptosis and angiogenic factors were also studied. The enzyme activity of apoptosis efector caspase-3 was colorimetrically determined. Axitinib and dasatinib combination lowered the survival rate of PPC-1 cells but enhanced the survival rate of TSU-Pr1 cells. The protein expression levels in apoptosis and angiogenesis factors were also found to be in contrast between the two cell lines. PPC-1 and TSU-Pr1 cells displayed a different response to axitinib with dasatinib, which explains different expression levels of regulators of cell-cycle, apoptosis and angiogenesis.</p><p> </p>

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