scholarly journals Long-Term Side Effects of Adjuvant Therapy in Primary Breast Cancer Patients: Results of a Web-Based Survey

Breast Care ◽  
2019 ◽  
Vol 14 (2) ◽  
pp. 111-116 ◽  
Author(s):  
Renate Haidinger ◽  
Ingo Bauerfeind
Keyword(s):  
Breast Cancer ◽  
Peripheral Neuropathy ◽  
Side Effects ◽  
Primary Breast Cancer ◽  
Sleep Disturbances ◽  
Breast Cancer Survivors ◽  
Time Frame ◽  
Breast Cancer Patients ◽  
Web Based

Background: Chronic treatment sequelae may substantially reduce the long-term quality of life in breast cancer survivors. Methods: We report a comprehensive Web-based survey on the presence of long-term side effects of adjuvant anti-breast cancer therapy in 1,506 patients who had been diagnosed with primary breast cancer at least 1 year before. Results: Fatigue, depression, depressive mood, concentration deficit, pain, changes of mucosa and skin appendages, as well as symptoms of peripheral neuropathy were the most prevalent reported complaints. Chemotherapies - taxane-based regimens in particular - were associated with increased rates of long-term symptoms, including persistent peripheral neuropathy. Overall, the data show a substantial prevalence of a wide variety of potentially treatment-associated symptoms over a protracted time frame after the diagnosis of breast cancer. The burden of symptoms was high for fatigue, depression, sleep disturbances, pain, and peripheral neuropathic symptoms. Conclusion: Estimating the burden of chronic toxicities should contribute to enhance rational decision-making on treatments including chemotherapy in patients with low versus high risk of recurrence.

Distress and body image due to altered appearance in posttreatment and active treatment of breast cancer patients and in general population controls

2017 ◽  
Vol 16 (2) ◽  
pp. 137-145 ◽  
Author(s):  
Danbee Kang ◽  
Eun-Kyung Choi ◽  
Im-Ryung Kim ◽  
Seok Jin Nam ◽  
Jeong Eon Lee ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Body Image ◽  
General Population ◽  
Cancer Patients ◽  
Active Treatment ◽  
Breast Cancer Survivors ◽  
Breast Cancer Patients ◽  
Skin Changes ◽  
Population Controls

ABSTRACTObjective:Our objective was to evaluate long-term altered appearance, distress, and body image in posttreatment breast cancer patients and compare them with those of patients undergoing active treatment and with general population controls.Method:We conducted a cross-sectional survey between May and December of 2010. We studied 138 breast cancer patients undergoing active treatment and 128 posttreatment patients from 23 Korean hospitals and 315 age- and area-matched subjects drawn from the general population. Breast, hair, and skin changes, distress, and body image were assessed using visual analogue scales and the EORTC BR–23. Average levels of distress were compared across groups, and linear regression was utilized to identify the factors associated with body image.Results:Compared to active-treatment patients, posttreatment patients reported similar breast changes (6.6 vs. 6.2), hair loss (7.7 vs. 6.7), and skin changes (5.8 vs. 5.4), and both groups had significantly more severe changes than those of the general population controls (p < 0.01). For a similar level of altered appearance, however, breast cancer patients experienced significantly higher levels of distress than the general population. In multivariate analysis, patients with high altered appearance distress reported significantly poorer body image (–20.7, CI95% = –28.3 to –13.1) than patients with low distress.Significance of results:Posttreatment breast cancer patients experienced similar levels of altered appearance, distress, and body-image disturbance relative to patients undergoing active treatment but significantly higher distress and poorer body image than members of the general population. Healthcare professionals should acknowledge the possible long-term effects of altered appearance among breast cancer survivors and help them to manage the associated distress and psychological consequences.

From helplessness to self help: Breast cancer surviorship in India.

2017 ◽  
Vol 35 (5_suppl) ◽  
pp. 208-208 ◽  
Author(s):  
Rebecca DeSouza ◽  
Shona Milon Nag ◽  
Rama Sivaram ◽  
Anupama Dutt Mane
Keyword(s):  
Breast Cancer ◽  
Side Effects ◽  
Cancer Survivors ◽  
Support Group ◽  
Breast Cancer Survivors ◽  
Social Stigma ◽  
Lifestyle Changes ◽  
Social Health ◽  
Annual Conference ◽  
Breast Cancer Patients

208 Background: In The Indian Scenario, a diagnosis of cancer is accompanied with social stigma and emotional upheavals, especially in breast cancer patients. They are typically thinking: “I would be less of a woman,” “I don’t know if people understand me,” “I feel isolated from myself, my family and my friends,” “Would I be normal again?” “Do I know how to help myself?” or “What will happen in the future, to my kids, to my husband?” Methods: All of these concerns are not always addressed by the medical professions. To address these issues, the Indian Breast Cancer Survivors Conference was organized as an annual conference with an attendance of 200-250 breast cancer survivors from the state of Maharashtra, India. The conference would address the psychological, emotional and social distress experienced by the patients with an aim from living a longer life to living a better and fulfilled life. Results: The emphasis of the sessions were educational (with recent updates on the surgical, medical and radiation therapy aspects of breast cancer treatment), practical (emphasized important issues like side-effects of treatment, patient advocacy, complementary therapies, spirituality, lifestyle changes, etc.), and entertaining. The summary and outcomes of the last 5 annual survivorship conferences will be described and enumerated. Results of questionnaires administered during the last 2 conferences and addressing health behavior patterns of survivors will be presented. Conclusions: We can evaluate through post conference support group discussions and conference feedback, qualify patient psychological and social health as 1) Physical:There are side effects but I choose to go on; 2) Mental: There are times that I am low, depressed, anxious, scared, guilty, but this is my new normal; 3) Emotional:Little things upset me, angry quickly but I am dealing with it; 4)Spiritual:Moved away from bargaining with God to accepting, from rituals to spiritual; 5) Social:don’t hesitate to reach out for support and to support; and 5) Intellectual:Knowledge is power, so I have learned to ask, to question, and then to decide. Achieving psychological and social health is the effort of the patient, the treating team and the support group.

scholarly journals Resistance Exercise for Breast Cancer Patients? Evidence from the Last Decade

Breast Care ◽  
2021 ◽  
pp. 1-7
Author(s):  
Lars Gerland ◽  
Freerk T. Baumann ◽  
Timo Niels
Keyword(s):  
Breast Cancer ◽  
Side Effects ◽  
Resistance Training ◽  
Muscle Strength ◽  
Cancer Patients ◽  
Exercise Intervention ◽  
Large Field ◽  
Breast Cancer Patients ◽  
The Impact

<b><i>Background:</i></b> Breast cancer is associated with many therapy-induced side effects that impact patients’ lives from diagnosis to long-term survivorship. Physical activity has become an important and proven supportive measure in treating side effects like loss of muscle strength, fatigue, chemotherapy-induced peripheral neuropathy, lymphedema, and loss of quality of life. Resistance training (RT) is an established exercise intervention for breast cancer patients, but the correct type, timing, intensity, and duration of exercise remain unclear. It is necessary to investigate different resistance training interventions and their effects on breast cancer patients by covering all stages of treatment, beginning with prehabilitation, through the period of acute therapy, to long-term survivorship. <b><i>Conclusion:</i></b> Upon evaluation of randomized controlled trials (RCTs) from the past decade, RT was found to be feasible and safe. Furthermore, there is evidence on the impact of RT on muscle strength, CRF and QoL amongst other factors. Studies implementing mixes of aerobic and strength exercises are rather common, but RCTs of RT-only protocols remain scarce. Different strength training protocols at distinct stages of breast cancer treatment have been conducted, but with the complexity of treatments and the variety of training styles, a large field of study remains. <b><i>Key Messages:</i></b> Although the overall data on RT for breast cancer patients has increased, there are many different methodological approaches and testing measures as well as gaps in study documentation. There is still very little of the evidence that would facilitate the compilation of standardized and individualized guidelines.

scholarly journals Short Communication...Therapeutic Values of Yoga and Qigong – Are These Exercises Suitable for Breast Cancer Survivors?

2014 ◽  
Vol 20 (1) ◽  
pp. 58-60
Author(s):  
Shirley S.M. FONG ◽  
Shamay S.M. NG ◽  
W. S. LUK ◽  
Ada W.W. MA
Keyword(s):  
Breast Cancer ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Well Being ◽  
Breast Cancer Patients ◽  
Cancer Treatments ◽  
Shoulder Dysfunction ◽  
Health And Well Being

Breast cancer is one of the most common malignant diseases in women. The mortality rate of breast cancer patients is rather low and the survival rate continues to increase worldwide (Siegel, Naishadham, & Jernal, 2012). However, conventional breast cancer treatments (e.g., mastectomy and radiotherapy) often lead to long-term physical impairments such as lymphedema and shoulder dysfunction (Cheville & Tchou, 2007). These side-effects may diminish the psychological well-being and quality of life of breast cancer survivors (Fong et al., 2013a). Promoting the health and well-being of this growing population has, therefore, become a major concern for healthcare professionals. (Abstract taken from first paragraph of document)

scholarly journals A Brief Review on Breast cancer treatment and current challenges

2021 ◽  
pp. 27-31
Author(s):  
Isha Shah ◽  
Nensi Raytthatha
Keyword(s):  
Breast Cancer ◽  
Side Effects ◽  
Cancer Treatment ◽  
Effective Treatment ◽  
Breast Cancer Survivors ◽  
Early Stage ◽  
Breast Cancer Treatment ◽  
Good News ◽  
Number Of Patients

Cancer is a global disease, so rational and effective treatment is needed. Breast cancer is one of the most common cancers in a woman and now the number of patients is increasing day by day. Therefore, development and research are underway for the effective treatment of breast cancer. Breast cancer treatment depends on the stage of cancer and the risk, based on this medical agents should be employed on patients to prevent breast cancer. In addition, breast cancer survival rates are rising which is good news for science but on the other hand the side effects of treatment present new challenges. An early-stage cancer diagnosis can save a patient's active or healthy life due to long-term and varied treatments that can be used for cancer otherwise breast cancer is a life-threatening disease. Breast cancer survivors not only have negative side effects of cancer treatment but also, have many other issues of previous treatment so it is a challenge for researchers. As a result, this review article deals with the effective treatment of breast cancer and its side effects. This review will help researchers better understand the long-term medical implications for breast cancer.

Long term peripheral neuropathy symptoms in breast cancer survivors.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e21599-e21599
Author(s):  
Moaath Khader Mustafa Ali ◽  
Machelle Moeller ◽  
Lisa A. Rybicki ◽  
Halle C. F. Moore
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Peripheral Neuropathy ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Multivariable Analysis ◽  
Multivariable Logistic Regression Analysis ◽  
Patient Reported ◽  
Associated Risk Factors

e21599 Background: Peripheral neuropathy (PN) is a common complication from chemotherapy (CTX), associated with significant morbidity, and may improve with time. The prevalence of long-term PN symptoms in breast cancer survivors is not well known. We sought to explore PN symptoms and associated risk factors among breast cancer survivors at least 2 years out from diagnosis. Methods: We performed a cross-sectional retrospective study investigating the prevalence of patient-reported numbness/tingling symptoms as a surrogate for PN in breast cancer survivors at our institution. We included patients with stage 0-III breast cancer who completed a questionnaire about symptoms and life-style habits at a survivorship visit that occurred 2 or more years after initial diagnosis. We evaluated the prevalence of PN and associated risk factors using univariable and multivariable logistic regression analysis; results are shown as odds ratio (OR) and 95% confidence interval (CI). Results: 605 patients assessed between April 2009 and October 2016 met eligibility for analysis. Median age was 60 (31-93) years. Median number of years from diagnosis to assessment was 6.3 (2-21). All patients had surgery and 62% had CTX. Twenty-seven percent reported PN. On univariable analysis, obesity, stage II & III, mastectomy, PN before diagnosis, and receipt of taxane CTX were associated with PN (all p < 0.05). Patients who were older, exercised before diagnosis, had ER/PR-positive disease and who received endocrine therapy reported less PN (all p < 0.05). On multivariable analysis, only receipt of docetaxel (OR: 2.18, CI: 1.22- 3.88) or paclitaxel (OR: 4.07, CI: 2.54-6.50) and reporting PN symptoms before diagnosis (OR: 3.28, CI: 1.49-7.21) were associated with PN. Among patients without pre-existing PN symptoms, 15%, 19%, 28% and 43% reported long-term PN after no CTX, non-taxane CTX, docetaxel CTX and paclitaxel CTX respectively. Conclusions: At a median follow-up of 6.3 years from diagnosis, 28% of survivors in our cohort who had received docetaxel and 43% who had received paclitaxel report long-term PN symptoms compared with 15-19% in those who received no or non-taxane CTX. These data can help inform patients and clinicians regarding long-term PN risk following CTX.

Triggers of Uncertainty About Recurrence and Long-Term Treatment Side Effects in Older African American and Caucasian Breast Cancer Survivors

2004 ◽  
Vol 31 (3) ◽  
pp. 633-639 ◽  
Author(s):  
Karen M. Gil ◽  
Merle H. Mishel ◽  
Michael Belyea ◽  
Barbara Germino ◽  
Laura S. Porter ◽  
...  
Keyword(s):  
Breast Cancer ◽  
African American ◽  
Side Effects ◽  
Cancer Survivors ◽  
Breast Cancer Survivors ◽  
Term Treatment ◽  
Treatment Side Effects ◽  
Long Term Treatment
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