scholarly journals Clinical pharmacoepidemiology of antibiotics usage in intensive care unit of cancer special hospital

2020 ◽  
Vol 9 (3) ◽  
pp. 169
Author(s):  
Akrom Akrom ◽  
Rafiastiana Capritasari

The pattern of antibiotics use in cancer patients in the intensive care unit (ICU) of dharma is cancer special hospital (DCSH) has not been identified. The purpose of this study is to determine the pattern of antibiotics use in cancer patients treated in the ICU of DCSH from 2012-2014. This study was observational with a cross-sectional design. The data collection is done retrospectively. The inclusion criteria to recruit the subjects, i.e. Adult patients who had nosocomial infections in the ICU; Patients with medical records in the ICU who received antibiotics in the 2012-2014 periods. Patients originating from inpatients (wards); Patients with medical records were read. The exclusion criteria were postoperative patients and Patients with incomplete medical records. We collected data from medical records of cancer patients who had been admitted to the ICU in 2012-2014, medication administration records, sample submission, and laboratory records. There are 202 cancer patients including in the study. Leukemia and breast cancer were the most cancer’s diagnosis in the Subject. More than two hundred cancer patients were receiving antibiotic therapy, with more than 50% of them were diagnosed with pneumonia, followed by central infection (>20%) and urinary tract infection (>10%). The antibiotic most frequently used was meropenem, with 33.8%. The three most commonly used antibiotics from 2012 to 2014 were meropenem, levofloxacin, and ceftriaxone.

2021 ◽  
Vol 21 (2) ◽  
pp. 547-552
Author(s):  
Henrique Yuji Watanabe Silva ◽  
Felipe Teixeira de Mello Freitas

Abstract Objectives: to describe the epidemiology of invasive candidiasis in a neonatal intensive care unit. Methods: cross-sectional study that included all neonates with invasive candidiasis confirmed by blood culture from April 2015 to June 2018. Demographic, clinical and microbiological data were analyzed, comparing neonates with extreme low birth weight (ELBW) with neonates ≥ 1000g birth weight, considering a p <0.05 as statistically significant. Results: there were 38 cases of invasive candidiasis, resulting in an overall incidence of 2.5%. Twelve (32%) were ELBW neonates and 26 (68%) neonates ≥ 1000g birth weight, an incidence of 4.4% and 2.0%, respectively. Abdominal surgery was more frequent among neonates with birth weight ≥ 1000g compared to ELBW neonates (85% vs. 17%; p <0.01), as well as the median in days of antibiotics use (18 vs. 10.5; p = 0.04). The median in days of mechanical ventilation was more frequent among ELBW neonates (10 vs. 5.5; p = 0.04). The majority of Candida species were non-albicans (64%). Fatality rate was 32%. Conclusions: the incidence of invasive candidiasis among neonates with birth weight ≥ 1000g was higher than that found in the literature. This group has a higher proportion of gastrointestinal malformations that require surgery. Thus, fluconazole prophylaxis may be necessary for a broader group of neonates.


Author(s):  
Silvia Mayumi Okuma ◽  
Ana Flávia Marostegan De Paula ◽  
Gabriela Pereira Do Carmo ◽  
Marcela Maria Pandolfi

A internação na UTI (Unidade de Terapia Intensiva),  e o processo de adoecimento podem gerar implicações negativas ao sujeito como alterações motoras, cognitivas e na participação nas atividades de vida diária. Muitos pacientes compartilham más experiências vivenciadas durante a internação em UTI (as quais desorganizam o sujeito, identificar as necessidades pode contribuir na elaboração do plano de tratamento adequado às demandas do paciente. Dessa forma,o objetivo do trabalho foi de  caracterizar o perfil desses pacientes atendidos pela Terapia Ocupacional na UTI Adulto. Realizou-se uma pesquisa transversal observacional da qual participaram 37 sujeitos internados na UTI adulto de um hospital público da Zona Leste do município de São Paulo no período de junho a agosto de 2016. Verificou-se que as características mais presentes entre os participantes dos grupos conforme gênero, idade e dias de internação foram:  fraqueza, dor, mobilidade reduzida, limitação no autocuidado, banho e higiene foram os mais presentes entre os participantes. Déficit cognitivo e queixa de memória foram os mais elencados no grupo dos idosos. A internação na UTI e o processo de adoecimento podem gerar implicações negativas ao sujeito como alterações motoras, cognitivas e na participação nas atividades de vida diária. Com base nos resultados identificou-se que os pacientes internados apresentaram fatores que interferem na participação nas atividades de vida diária (autocuidado, banho, higiene, arrumar-se no leito, alimentação e controle de esfíncter), e a atuação da Terapia Ocupacional pode contribuir de forma a minimizar os efeitos deletérios decorrentes da hospitalizaçãoAbstractMany patients live bad experiences during their stay in ICU, that disrupt the subject. Identifying the needs of the person can contribute to the elaboration of the treatment plan. Thus, is importante to identify the profile of the patients treated by Occupational Therapy in an Adult Intensive Care Unit. The study consisted of an observational cross-sectional study in which 37 subjects were hospitalized in the adult ICU of a public hospital in the East of the city of São Paulo from June to August 2016. The presence of weakness, pain, reduced mobility, self-care limitation, bathing and hygiene were the most frequent among the participants according to gender, age and days of hospitalization. Cognitive deficit and memory complaints were the most prominent in the elderly group. ICU hospitalization and the process of illness may cause negative implications for the subject, such as motor and cognitive impairment and difficulties in activities of daily living. The data made it possible to identify the profile of the patients treated by Occupational Therapy in the adult ICU, which makes it possible to guide the practice itself.Keywords: Occupational Therapy, Intensive Care Unit, Adult. ResumenMuchos pacientes comparten de las malas experiencias vivenciadas durante la internação en UCI, las cuales desorganizan el sujeto. Identificar las necesidades del sujeto puede contribuir en la elaboración del plan de tratamiento adecuado a las demandas del paciente. De esa forma, se resalta la importancia de identificar el perfil de los pacientes atendidos por la Terapia Ocupacional en la Unidad de Cuidados Intensivos de Adultos. Se realizó una investigación transversal observacional en que fueron evaluados 37 sujetos ingresados en la UCI de adultos de un hospital público de la Zona Este del municipio de São Paulo en el periodo de junio a agosto de 2016. Se verificó que presencia de flaqueza, dolor, movilidad reducida, limitación en el autocuidado, baño e higiene fueron los más presentes entre los participantes de los grupos según género, edad y días de internação. Déficit cognitivo y queja de memoria fueron los más elencados en el grupo de los ancianos. La internação en la UCI y el proceso de adoecimento pueden generar implicaciones negativas al sujeto como alteraciones motoras, cognitivas y en la participación en las actividades de vida diaria. Los datos posibilitaron identificar el perfil de los pacientes atendidos por la Terapia Ocupacional en la UCI de adultos, lo que posibilita a orientar la práctica.Palabras clave: Terapia Ocupacional, Unidad de Cuidados Intensivos, Adulto.


2019 ◽  
Author(s):  
Susy Puspasari

Background: Comatosepatient’sexperiencesdeclineineyereflex.However,this issue receive less attention from the healthcare professional,particularly in the intensive care unit. Few studies exploring the associated factors of nurse implementation of eye care in intensive care unit. Theory of Planned Behavior (TPB) has been well-known as a framework to explore the behavior relation factors including nurse’s background, the certainty of behavior, normative, and control beliefs factors. Objectives: The purpose of this study was to analyze the factors that influence nurses in the implementation of eye care towards coma patients in intensive care rooms. Methods: This study used cross-sectional design to the nurses who working in intensive care units. The number ofsamplesusedinthisstudywastotalsampling.Atotalof104nursesworkinintensive care units participate as a sample of this study. A set questionnaire designed by the researcher was used for data collection. Data analysis was use distribution frequency, mean, SD and Chi square. Results:Half of nurse (50.96%) had a favorable background, unfavorable on normative assurance and belief factors. In the background factors resulted that nurse have favorable with a value of 50.96%. Conclusions: It is suggested that nurses who work in the hospital to use the information from this study to enhance their knowledge about eye care for comatose patient routinely and continuously. As for the intensive care unit, it is recommended to enforce algorithm, standard procedure, and particular supervision on the conduction of eye care for comatose patients.


2010 ◽  
Vol 18 (5) ◽  
pp. 888-894 ◽  
Author(s):  
Maria Lurdemiler Sabóia Mota ◽  
Islene Victor Barbosa ◽  
Rita Mônica Borges Studart ◽  
Elizabeth Mesquita Melo ◽  
Francisca Elisângela Teixeira Lima ◽  
...  

This study evaluates the knowledge of nurses working in intensive care units concerning recommendations for the proper administration of medication through nasogastric and enteral tubes. This exploratory-descriptive study with a quantitative approach was carried out with 49 nurses in an intensive care unit of a tertiary hospital in Fortaleza, CE, Brazil. A total of 36.7% of nurses reported they disregard the dosage forms provided by the pharmacy at the time of administering the medication through tubes. Metal, wood, or a plastic mortar is the method most frequently reported (42.86%) for crushing prescribed solid forms; 32.65% leave the drugs in 20ml of water until dissolved; 65.3% place the responsibility for choosing the pharmaceutical formulation and its correlation with the tube site, either into the stomach or into the intestine, on the physician. The results indicate there is a gap between specific literature on medication administered through tubes and knowledge of nurses on the subject.


2021 ◽  
pp. 105477382110117
Author(s):  
Altun Baksi ◽  
Hamdiye Arda Sürücü ◽  
Hale Turhan Damar ◽  
Meltem Sungur

This study aimed to examine the relationship between older adults’ readiness for discharge after surgery and satisfaction with nursing care and effects factors, using a descriptive, cross-sectional design that included 204 older adults. Examining the state of readiness for the discharge of older adults who underwent surgery in terms of the expected support sub-dimension of patients revealed that the presence of someone to support home care, the existence of health insurance, living with someone, undergoing emergency surgery, and being illiterate were statistically significant predictors. Thought of improvement in terms of nursing care between prior hospitalization and the latest hospitalization, use of intensive care unit, male, nursing care satisfaction, and the existence of health insurance were statistically significant predictors of the readiness for discharge in older adults after surgery in terms of personal status sub-dimension. Accordingly, an individual approach that takes these characteristics/variables into account is recommended when planning discharge.


Rev Rene ◽  
2015 ◽  
Vol 16 (2) ◽  
Author(s):  
Carla Portolan Ribeiro ◽  
Caroline De Oliveira Silveira ◽  
Eliane Raquel Rieth Benetti ◽  
Joseila Sonego Gomes ◽  
Eniva Miladi Fernandes Stumm

Objective: to identify nursing diagnoses of patients in mediate postoperative period of cardiac surgery. Methods: descriptive,cross-sectional design with 26 patients in mediate postoperative period of cardiac surgery, in an intensive care unit. Datawere collected through a form of socio-demographic/clinic characterization and nursing diagnoses. Results: one identified15 risk nursing diagnoses and 34 real diagnoses, and the most common were related to the domain safety and protection.Conclusion: the identification of nursing diagnoses in patients after cardiac surgery allows one to direct nursing care andsupport appropriate interventions to individual needs, because patients in these conditions require immediate and accurateinterventions.


e-CliniC ◽  
2019 ◽  
Vol 7 (2) ◽  
Author(s):  
Reinhard C. Taroreh ◽  
Harold F. Tambajong ◽  
Diana Ch. Lalenoh

Abstract: Sepsis is defined as organ dysfunction that threatens life due to disregulated response of vulnerable host to the infection agent. Antimicrobial therapy is one of the main therapies in the management of septic cases. Survival sepsis campaign guidelines in 2016 recommended antimicrobial administration in one hour after being diagnosed as sepsis. This study was aimed to determine the pattern of antimicrobial administration among septic patients in the Intensive Care Unit of RSUP Prof. Dr. R. D. Kandou Manado. This was an observational analytical study with a cross-sectional design. Samples were intensive care unit patients of RSUP Prof. Dr. R. D. Kandou Manado diagnosed as sepsis and its classification obtained from the Medical Record Installation data for the period of January to June 2019. The results showed a total of 35 septic patients consisting of 16 females (45.7%) and 19 males (54.3%). The time of antimicrobial administration ≤1 hour was found in 21 cases (60%). The most frequent antimicrobial administered was ceftriaxone in 13 cases (37.1%). The mortality rate after >48 hours was 13 cases (59%). In conclusion, most antimicrobial administration was in 1 hour after being diagnosed as sepsis and ceftriaxone was the most frequent antimicrobial given. Mortality rate after administration of antimicrobial was still high.Keywords: sepsis, ICU, antimicrobial, mortality rate Abstrak: Sepsis didefinisikan sebagai disfungsi organ yang mengancam nyawa akibat disregulasi respon penjamu terhadap infeksi. Terapi antimikroba merupakan salah satu terapi utama dalam penatalaksanaan kasus sepsis. Pedoman Survival Sepsis Campaign tahun 2016 menyatakan pemberian antimikroba yang direkomendasikan ialah satu jam setelah terdiagnosiss sepsis. Penelitian ini bertujuan untuk mengetahui pola pemberian antimikroba pada pasien sepsis di Intensive Care Unit RSUP Prof. Dr. R. D. Kandou Manado. Jenis penelitian ialah analitik observasional dengan desain potong lintang. Sampel penelitian ialah pasien ICU Prof. Dr. R. D. Kandou Manado dengan diagnosis sepsis dan klasifikasinya, diperoleh dari data Bagian Instalasi Rekam Medik periode Januari-Juni 2019. Hasil penelitian mendapatkan total 35 pasien dengan diagnosis sepsis, terdiri dari 16 orang perempuan (45,7%) dan 19 orang laki-laki (54,3%). Waktu pemberian antimikroba ≤1 jam pada sebanyak 21 kasus (60%). Penggunaan antimikroba yang sering diberikan ialah ceftriaxone pada 13 kasus (37,1%). Angka kematian setelah >48 jam sebanyak 13 kasus (59%). Simpulan penelitian ini ialah sebagian besar pemberian antimikroba 1 jam setelah didiagnosis sepsis dengan ceftriaxone sebagai antimikroba yang paling sering diberikan. Angka kematian pasca pemberian antimikroba masih tinggi.Kata kunci: sepsis, ICU, antimikroba, angka kematian


2019 ◽  
Vol 9 (9) ◽  
pp. 81
Author(s):  
Mohammad M. Al Barraj ◽  
Mirna Fawaz ◽  
Lina Kurdahi Badr

Background and objective: Having a family member admitted to Intensive Care Unit (ICU) is stressful and confusing for family members.  The aim of this study was to assess the perception of family members and nurses of their needs and whether those needs are met in four ICUs in Lebanon.Methods: A descriptive cross-sectional design using the Arabic version of Critical Care Family Need Inventory (CCFNI) and the Needs Met Inventory (NMI) were utilized to investigate the needs of 50 family members of patients and 50 nurses.Results: Seventeen of 30 need items on the CCFNI were significantly different between family members and nurses mostly related to ‘Information’ and ‘Assurance’. Family members also varied significantly on 5 out of 30 items on the NMI mostly related to ‘Support’. There were significant differences in needs between family members in terms of gender, age, and education, and significant differences in perceived needs based on the gender, years of experience, and age of nurses.Conclusions: The findings provide insight for nurses to consider the different needs of families, the effect of socio-demographic variations when providing care, and to be attuned to the needs of family members for understandable information and assurance of the wellbeing of patients in ICUs.


2009 ◽  
Vol 17 (3) ◽  
pp. 302-307 ◽  
Author(s):  
Simoni Pokorski ◽  
Maria Antonieta Moraes ◽  
Régis Chiarelli ◽  
Angelita Paganin Costanzi ◽  
Eneida Rejane Rabelo

OBJECTIVES: To describe the steps of the nursing process as prescribed in the literature and to investigate the process as actually applied in the daily routine of a general hospital. METHODS: Cross-sectional retrospective study (May/June 2005), performed in a hospital in Porto Alegre, RS. Medical records of adult patients admitted to a surgical, clinical or intensive care unit were reviewed to identify the nursing process steps accomplished during the first 48h after admission. The form for data collection was structured according to other reports. RESULTS: 302 medical records were evaluated. Nursing records and physical examination were included in over 90% of them. Nursing diagnosis was not found in any of the records. Among the steps performed, prescription was the least frequent. Evolution of the case was described in over 95% of the records. CONCLUSIONS: All nursing steps recommended in the literature, except for diagnosis, are performed in the research institution.


2021 ◽  
Vol 10 (5) ◽  
pp. 1145
Author(s):  
Olivier Peyrony ◽  
Jean-Paul Fontaine ◽  
Eloïse Trabattoni ◽  
Lionel Nakad ◽  
Sylvain Charreyre ◽  
...  

Background: Very little data are available concerning the prehospital emergency care of cancer patients. The objective of this study is to report the trajectories and outcomes of cancer patients attended by prehospital emergency services. Methods: This was an ancillary study from a three-day cross-sectional prospective multicenter study in France. Adult patients with cancer were included if they called the emergency medical dispatch center Service d’Aide Médicale Urgente (SAMU). The study was registered on ClinicalTrials.gov (NCT03393260, accessed on 8th January 2018). Results: During the study period, 1081 cancer patients called the SAMU. The three most frequent reasons were dyspnea (20.2%), neurological disorder (15.4%), and fatigue (13.1%). Among those patients, 949 (87.8%) were directed to the hospital, among which 802 (90.8%) were directed to an emergency department (ED) and 44 (5%) were transported directly to an intensive care unit (ICU). A mobile intensive care unit (MICU) was dispatched 213 (31.6%) times. The decision to dispatch an MICU seemed generally based on the patient’s reason for seeking emergency care and the presence of severity signs rather than on the malignancy or the patient general health status. Among the patients who were directed to the ED, 98 (16.1%) were deceased on day 30. Mortality was 15.4% for those patients directed to the ED but who were not admitted to the ICU in the next 7 days, 28.2% for those who were admitted to ICU in the next 7 days, and 56.1% for those patients transported by the MICU directly to the ICU. Conclusion: Cancer patients attending prehospital emergency care were most often directed to EDs. Patients who were directly transported to the ICU had a high mortality rate, raising the question of improving triage policies.


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