scholarly journals Стоматологічний статус осіб, схильних до регулярного активного куріння

2017 ◽  
Author(s):  
O. Ya. Lavrin ◽  
V. V. Shcherba ◽  
I. Ya. Krynytska
Keyword(s):  
Periodontal Disease ◽  
Periodontal Diseases ◽  
Pathological Process ◽  
Control Group ◽  
Periodontal Tissue ◽  
Active Smoking ◽  
Periodontal Tissues ◽  
Increased Risk ◽  
Periodontal Index ◽  
Central District

Smoking is associated with significantly increased risk of diseases of organs and tissues of the oral cavity, especially periodontal pathology and cancer of the mouth.The aim of the study – to investigate the prevalence, structure and clinical course of periodontal tissue diseases in people prone to regular active smoking.Materials and Methods. A study of 120 visitors who had undergone preventive examinations in the Clinic of Zbarazh Central District Municipal Hospital exposed to regular active smoking was performed. To assess the degree of inflammation in periodontal tissues we used marginally-papillary-alveolar index, periodontal index, the Green-Vermilyon index.Results and Discussion. Dental examination of persons exposed to regular active smoking, revealed periodontal disease in 102 individuals (85.0 %), intact periodont – 18 persons (15.0 %). At the same time, investigation of 30 control individuals showed periodontal disease in 12 persons (40.0 %), clinically healthy periodontal tissue – in 18 persons (60.0 %). PMA index of individuals exposed to regular active smoking, treated as severe gingivitis and was significantly higher than data of the control group in 2.5 times. Average numerical values of periodontal index in patients exposed to regular active smoking answered moderate periodontitis and significantly were higher than data of the control group in 4 times. Oral hygiene status in 62 % of those exposed to regular active smoking, was poor, 7 % – very poor, 22 % – satisfactory, 9 % – good. Average numerical values of Green-Vermilyon index in smokers was significantly higher than data of the control group in 3.1 times.Conclusions. Thus, smoking contributes to increasing of diffuse periodontal diseases and deepening of pathological process.

scholarly journals Clinical efficiency of ultraphonophoresis of Metrogyl Denta gel in mild periodontitis

2021 ◽  
Vol 25 (1) ◽  
pp. 48-53
Author(s):  
Alexander G. Volkov ◽  
Dmitry I. Morozov ◽  
Nataliya Zh. Dikopova ◽  
Egor E. Olesov ◽  
Alexandr I. Sinyakov
Keyword(s):  
Blood Circulation ◽  
Periodontal Diseases ◽  
Control Group ◽  
Comprehensive Treatment ◽  
Physical Factors ◽  
Periodontal Tissue ◽  
Moderate Severity ◽  
Functional Parameters ◽  
Periodontal Tissues ◽  
Periodontal Index

BACKGROUND: Periodontal diseases are one of the most common in dentistry. Along with the complications of caries, periodontitis is one of the causes of tooth loss. In the etiology of this disease, the leading role is played by the microbial factor, as well as microcirculatory disorders in periodontal tissues. The complex mechanism of periodontitis development involves a comprehensive treatment approach aimed at different links in the pathogenesis of the development of this disease. Among the numerous physical factors used in the treatment of periodontal diseases, ultraphonophoresis, which combines the effects of ultrasound and a medicinal substance, is not widely used. The study of the effectiveness of the use of Metrogil Denta gel ultraphonophoresis in the treatment of inflammatory periodontal diseases is of considerable scientific and practical interest. AIM: This study aimed to investigate the effect of ultraphonophoresis of gel on the clinical course of chronic generalized periodontitis of moderate severity. MATERIALS AND METHODS: Sixty patients (aged 3162) with chronic generalized periodontitis of moderate severity were examined and treated. In the main group (n=30), treatment included high-frequency ultrasound and antibacterial preparation of Metrogyl Denta gel applied to the periodontal tissue (ultraphonophoresis of Metrogyl Denta gel). In the control group (n=30 patients), Metrogyl Denta gel was injected into the periodontal tissue. RESULTS: Application of Metrogyl Denta gel for moderate periodontitis did not improve local blood circulation. Six months after treatment, nearly half of the examined patients showed signs of inflammation, which was accompanied by a worsening of periodontal index (PI), SchillerPisarev tests results, and rheography finding. Twelve months after treatment, 63% of the patients developed complications. CONCLUSIONS: There was further deterioration in the clinical and functional parameters. After ultraphonophoresis of Metrogyl Denta gel, there was a decrease in the readings of the SchillerPisarev test, PI, and normalization of the qualitative and quantitative indicators of the rheoparodontogram, which indicated a decrease in inflammation and activation of local blood circulation in the periodontium. In the long term after treatment, despite the increase in hygiene index, the relative stability of clinical and functional parameters was maintained. Even a year after treatment, the level of indicators did not reach the level obtained before treatment.

Comparative analysis of polymorphic variants of IL-17A and MMP-1 genes with the risk of developing chronic periodontitis in petrochemical workers

2020 ◽  
Vol 60 (10) ◽  
pp. 687-693
Author(s):  
Iskander I. Zaidullin ◽  
Denis O. Karimov ◽  
Lilija K. Karimova ◽  
Milyausha F. Kabirova ◽  
Rasima R. Galimova ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Clinical Manifestations ◽  
Control Group ◽  
Periodontal Tissues ◽  
Dental Examination ◽  
Number Of Patients ◽  
Increased Risk ◽  
Harmful Substances

The susceptibility to the development and progression of inflammatory periodontal diseases, which depends on genetic and external factors (smoking, stress, oral hygiene), varies widely. In the development of these diseases, an important role is played not only by the presence of periodontal pathogenic microorganisms, but also by the presence of congenital or acquired immunodeficiency, immunoregulatory defects. The immune system plays a key role in the physiological and pathological processes of periodontal tissues. In this regard, IL17, produced by CD4+ Th cells, which has both Pro-inflammatory and protective activity, is of particular interest in the pathogenesis of periodontitis. The aim of study was to identify the relationship between polymorphic loci of the IL-17A (rs2275913) and MMP-1 (rs1799750) genes and clinical manifestations of chronic periodontitis in petrochemical workers. Dental examination was performed in 92 ethylene oxide production workers with chronic periodontitis and 74 patients with chronic periodontitis who did not come into contact with chemical factors (control group). Genotyping of polymorphisms rs2275913 of the IL17A gene and rs1799750 of the MMP1 gene was performed by allele-specific real-time polymerase chain reaction (PCR). Hygienic assessment of the degree of air pollution of the working area with harmful substances was carried out by gas chromatography according to the guidelines for the determination of harmful substances in the air № 5098-89, № 3119-84. When comparing the results of studies of both groups, there were no statistically significant differences in the frequency distributions of allelic variants and genotypes of the IL-17A and MMP-1 genes. The AA/AG genotypes of the IL-17A gene were associated with an increased risk of severe disease compared to the GG genotype in workers in the main group (OR=6.1; 95% CI 1.33-28.5; p=0.021) and in the control group (OR=7.26; 95% CI 1.34-39.25; p=0.016). Carriers of the A allele in the control group increased the risk of severe chronic periodontitis by 2.4 times compared to carriers of the G allele (OR=2.41; 95% CI 1.19-4.87; p=0.014). During the dental examination of employees of the ethylene oxide plant, the clinical course of periodontal diseases was more severe in comparison with the control group, and the number of patients with severe periodontitis was twice as high. It was found that the AA/AG genotypes of the IL-17A gene and the carrier of the A allele are associated with increased susceptibility to the development of severe chronic periodontitis. The association between the MMP-1 gene polymorphism and the risk of severe forms of chronic periodontitis has not been established. A risk factor for the development of inflammatory periodontal diseases in employees of the petrochemical complex is a complex of harmful production factors.

scholarly journals DIAGNOSTIC AND PROGNOSTIC SIGNIFICANCE OF MICROBIAL FLORA IMBALANCE IN GINGIVAL BIOFILM

2020 ◽  
Vol 5 (2) ◽  
pp. 76-82
Author(s):  
G. A. Loban ◽  
T. O. Petrushanko ◽  
V. V. Chereda ◽  
M. O. Faustova ◽  
M. M. Ananieva ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Prognostic Significance ◽  
Fluid Composition ◽  
Dental Tissues ◽  
Periodontal Tissues ◽  
Dmf Index ◽  
Increased Risk ◽  
Hard Dental Tissues

Background. Periodontal tissues inflammatory diseases are widespread among young people. Objective. This study was aimed at elaborating the method to assess risks of periodontal inflammatory diseases and determining its efficacy depending on the state of dental tissues, gum tissues and sex.          Methods. The study included 182 students (93 men, 89 women) aged 19-29: 22 individuals had no lesions of hard dental tissues and no signs of periodontal disease; 51 individuals were found to have DMF index <6; 52 individuals – DMF index ≥6; 57 individuals were diagnosed with chronic catarrhal gingivitis. Primary groups were formed in autumn; re-examination was carried in spring. The research participants were assessed for detection of risks of periodontal inflammatory disease by the method developes by the authors (Patent UA 54041). Results. The study revealed that the risk of development of preiodontitis increases in individuals with high caries and gingivitis intensity. In spring, more individuals suffer from microbial imbalance in in the composition of gingival sulcus fluid and decrease in the mean stability coefficient value that indicates an increased risk of inflammatory periodontal disease development. Women were less likely to experience seasonal dysbiotic changes in the gingival sulcus fluid composition compared with men. Conclusions. The method suggested for assessment of the risk of periodontal inflammatory diseases is of high informativeness. It allows clinicians detecting early pre-nosological signs of oral microbiocenosis imbalance that enhances the effectiveness of early diagnosis of inflammatory periodontal diseases.

scholarly journals SOME ASPECTS OF THE EATIOLOGY OF PARODONTUS DISEASES. (LITERATURE REVIEW)

2018 ◽  
pp. 54-59
Author(s):  
N.N. Saveleva ◽  
I.I. Sokolova ◽  
S.I. German ◽  
T.V. Tomilina
Keyword(s):  
Gastrointestinal Tract ◽  
Periodontal Disease ◽  
Structural Damage ◽  
Inflammatory Diseases ◽  
Periodontal Diseases ◽  
Clinical Manifestations ◽  
Pathological Process ◽  
Chronic Obstructive ◽  
Internal Organs ◽  
Periodontal Tissues

The review of the scientific literature is devoted to the topical issues of studying the etiology of periodontal diseases, which are one of the most common and complex pathologies of the maxillofacial region. Analysis of recent studies proves a stable relationship between the development of periodontal diseases and disorders in the immune system, the neurohumoral system, metabolic disorders, genetic predisposition, and so on. The article presents the data obtained in the course of studying the literature on the role of disorders in the functioning of individual organs (gastrointestinal tract, liver, lungs, heart, and urinary system) in the development of chronic periodontal diseases. The article notes that the anatomical and physiological proximity of the periodontal and digestive tract tissues, the generality of innervation and humoral regulation create prerequisites for the involvement of periodontal disease in the pathological process in diseases of the gastrointestinal tract. One of the main etiological factors in the development of inflammatory diseases of the gastrointestinal tract and periodontium is Helicobacter pylori, which is found in the loci of the oral cavity: in the oral and gingival fluid, on the mucous membrane of the tongue and cheeks, and in the periodontal pockets. It is pointed out that the liver also occupies a special place in the development of periodontal diseases, which is explained by the performance of its significant functions for the human body: regulatory, metabolic, antitoxic and other. There is evidence that the pathology of periodontal disease plays a leading role in the structure of dental diseases in patients with chronic obstructive pulmonary diseases, which is clinically manifested by symptoms of generalized periodontitis of the І-ІІ degrees of development and its complications - partial or complete secondary adentia, and with tooth preservation - defects in dental series and violations of occlusion, function, aesthetics. Scientists suggest a general biological mechanism for the development of generalized periodontitis and cardiovascular diseases, linking the development of periodontal diseases in patients with cardiovascular pathology with microcirculatory disorders. The dependence of the severity of inflammatory changes in the periodontal tissues on the disturbances of salt metabolism in urolithiasis is proved. The data obtained indicate that diseases of the internal organs contribute to the structural damage of periodontal tissues and they are a risk factor for periodontal diseases, which necessitate the presence of not only theoretical knowledge and practical skills in dentistry, but also their awareness of the features and clinical manifestations of somatic pathology. An urgent and justified step in the treatment of periodontal diseases is also the involvement in the process of rendering complex dental care to internist doctors capable of quickly and qualitatively assessment the condition of the internal organs and the basic systems of the patient's body.

scholarly journals Comparative evaluation of expression of VEGF (vascular endothelial growth factors) in periodontal tissues of healthy, chronic and aggressive periodontitis patients: an immunohistochemical study

2020 ◽  
Vol 9 (1) ◽  
pp. 784-788
Keyword(s):  
Growth Factors ◽  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Aggressive Periodontitis ◽  
Control Group ◽  
Vascular Endothelial ◽  
Healthy Controls ◽  
Periodontal Tissues ◽  
Inflammatory Status

Periodontitis is a chronic inflammatory disease of the vascularized supporting tissues of the teeth. Angiogenesis (neovascularization) is the budding of new capillaries and is thought to be an essential process in the development of chronic inflammatory diseases. Inflamed tissues (such as gingiva coincident in periodontal disease) have evidence of enhanced expression of inflammatory mediators, many of which can promote angiogenesis. Of the various cytokines and growth factors that are involved in angiogenesis, the most potent agent that acts specifically on vascular epithelium is Vascular Endothelial Growth Factor. Even though angiogenesis is a prominent feature of both inflammation and healing, information about its role in periodontal lesions is limited. Hence the aim of the present study was the immunohistochemical evaluation of the expression of VEGF in the gingival tissues of chronic and aggressive periodontitis patients compared to the healthy controls. The present study was carried out in a total of 45 subjects with age range of 18-55 years, reporting to the Department of Periodontology, Rajarajeswari Dental College and Hospital, Bangalore. Gingival tissue samples were collected from all the 45 subjects and categorized into three groups based on their clinical findings as follows: Group 1 (Healthy), Group II (Chronic Periodontitis), Group III (Aggressive Periodontitis). Following sample collection, immunohistochemical staining of tissues was carried out and evaluation was done to compare the grades of expression of VEGF in the three groups. The expression of VEGF in blood vessels was also quantitatively evaluated. The results were statistically analyzed using Kruskal Wallis ANOVA and Mann Whitney test. There was a statistically significant higher expression of VEGF in both chronic periodontitis and aggressive periodontitis group as compared to the control group. Aggressive periodontitis cases showed higher grades of expression of VEGF compared to the chronic periodontitis cases and healthy controls. However, the difference in expression of VEGF was not statistically significant between the two forms of periodontitis. The presence of VEGF in both chronic and aggressive periodontitis clearly indicates the potent role played by VEGF as an inflammatory agent in the initiation and progression of periodontal diseases. Thus, VEGF might be used as a potential vascular marker for the assessment of severity and inflammatory status in periodontal disease.

scholarly journals CONDITION OF PERIODONTAL TISSUES IN PATIENTS WITH DERMATOSES

2018 ◽  
Vol 14 (4) ◽  
pp. 54-57
Author(s):  
Н. Чернышева ◽  
N. Chernyshova ◽  
Сергей Чуйкин ◽  
Sergey Chuykin ◽  
Гузель Акмалова ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Periodontal Disease ◽  
Lichen Planus ◽  
Oral Lichen Planus ◽  
Periodontal Diseases ◽  
Complex Treatment ◽  
Adequate Treatment ◽  
Periodontal Tissues ◽  
Periodontal Index ◽  
Oral Lichen

Background. Periodontal disease is one of the most common and complex pathologies in dentistry. It is known frequently damage to the tissues of the periodontal complex with dermatoses. The most relevant among the dermatoses of the mucous membrane of the mouth and the red border of the lips is oral lichen planus. Among the six clinical forms of red flat oral lichen planus and the red border of the lips, the exudative-hyperemic and erosive-ulcerous forms occur most often. Atypical form is much less common than other forms and is often diagnosed by dentists as an inflammatory periodontal disease. At the same time, the pathogenetic mechanisms of inflammatory processes in the gums, which are different in oral lichen planus, are not taken into account, which, accordingly, complicates adequate treatment. Objectives. The aim of the study was to analyze the periodontal status in patients with exudative-hyperemic, erosive-ulcerative and atypical forms of oral lichen planus. Methods. Under our supervision there were 181 patients with oral lichen planus, in whom a simplified Green-Vermillion hygiene index was determined. To assess the state of periodontal used periodontal index according to Russell. Results. When assessing the hygienic condition of the oral cavity, high values were observed in individuals with severe forms of the disease: erosive-ulcerative, exudative-hyperemic. The highest values of the periodontal index were found in patients with atypical, erosive and ulcerative forms of oral lichen planus. Conclusions. The results of the clinical examination of patients with oral lichen planus dictate, first of all, to include in the scheme of complex treatment of it the sanitization of oral cavity and complex treatment of inflammatory periodontal diseases as well.

scholarly journals Features of substitution of defects of tooth rows in persons with periodontal tissue diseases of different severity

2021 ◽  
Vol 105 (1) ◽  
pp. 82-87
Author(s):  
O. Doroshenko ◽  
◽  
O. Bida ◽  
Keyword(s):  
Periodontal Disease ◽  
Bone Tissue ◽  
Dental Implants ◽  
Alveolar Bone ◽  
Periodontal Diseases ◽  
Pathological Process ◽  
Periodontal Tissue ◽  
Dental Implantation ◽  
Orthopedic Rehabilitation ◽  
Abutment Teeth

Resume. The high prevalence of periodontal disease causes the urgency of finding ways to improve methods of diagnosis, treatment and prevention of complications of this disease. The complex clinical picture requires a differentiated approach to the choice of orthopedic rehabilitation of such patients taking into account the patient's age, degree of pathological changes and activity of the pathological process with mandatory immobilization of movable teeth by different types of splints and splint dentures. Depending on the degree of pathological changes in periodontal tissues, the size and topography of dentition defects and the severity of destructive-resorptive processes in the alveolar bone, the replacement of dentition defects should be planned using dental implants and splinttype dentures. The aim of the study. Improving the effectiveness of orthopedic treatment of periodontal diseases, burdened by defects of the dentition through the differentiated use of dental implants and splinting structures. Materials and methods. A comprehensive clinical and laboratory examination of 237 patients with clinically diagnosed periodontitis I–III degree, burdened by partial loss of teeth. From the specified contingent of persons we carried out orthopedic treatment of 98 patients aged from 30 to 69 years with periodontal diseases of various severity, aggravated by defects of dentitions of various size and localization. Cone-beam computed tomography was used for objective quantitative and qualitative assessment of periodontal tissue and bone tissue of the edentulous jaw in individuals with various clinical forms of periodontal disease, to determine the relative densitometric density of bone tissue, when planning dental implantation and for control its results. The localization of supracontacts was determined by occlusion. Diagnosis and elimination of traumatic occlusion were performed according to Jenkelson and Schuller [3]. Evaluation of the stability of dental implants was performed by frequency – resonance analysis of the stability of dental implants using the Osstell ISQ device. Results. According to the results of examination of 237 people and the division of patients into three age groups, the clinical features of the pathological process in the age aspect were established. The results of computed tomography of the dental apparatus of the subjects showed that periodontal disease in the age aspect in the dynamics is accompanied by the severity of destructive-resorptive processes in the alveolar bone, which are manifested in a decrease in the relative densitometric density of bone marrow and bone loss. Orthopedic rehabilitation of this contingent of persons was performed with the use of biologically indifferent structural materials and splinting orthopedic structures, including splinting of abutment teeth, removable prosthetics and dental implantation, as well as accompanying physiotherapy of prostheses. In the case of periodontitis of I–II degree with sufficient volume and density of bone tissue in the area of the dentition defect, high clinical efficacy was shown by the use of dental implantation in the case of gradual loading of the dental implant using a superstructure of own development. In the presence of medium and large defects of the dentition on the background of periodontitis II–III severity in the presence of significant pathological mobility of abutment teeth and insufficient volume and density of bone tissue in the area of the defect sufficient clinical effectiveness showed the use of removable dentures own design. Conclusions. Periodontal diseases in the age aspect in the dynamics are accompanied by pronounced destructive-resorptive processes in the alveolar bone, which are manifested by a decrease in the relative densitometric density of bone tissue and progressive loss of height of the alveolar process. Timely application of dental implantation due to the dosed gradual occlusal load on the alveolar bone helps to preserve the structure of the alveolar bone and the height of the alveolar process. In the presence of medium and large defects of the dentition on the background of periodontitis II–III severity in the presence of significant pathological mobility of abutment teeth and insufficient volume and density of bone tissue in the area of the dentition defect, the use of removable dentures of splinttype design is shown. To prevent complications of prosthetics and prolong the use of orthopedic structures, it is advisable to use photodynamic maintenance therapy. Key words: periodontal tissue disease, dentition defect, dental implantation, splint-type denture.

scholarly journals BIOCHEMICAL AND CLINICAL EVALUATION OF CORRELATION OF PERIODONTITIS AND EARLY CAROTID ATHEROSCLEROSIS

2019 ◽  
Vol 3 (12) ◽  
Author(s):  
Shazia Khatoon ◽  
Samir Jain
Keyword(s):  
Oral Health ◽  
Periodontal Disease ◽  
Lipid Profile ◽  
Clinical Evaluation ◽  
Carotid Atherosclerosis ◽  
Periodontal Diseases ◽  
Control Group ◽  
World Population ◽  
Periodontal Tissues ◽  
Systemic Health

Periodontal disease is a disease characterized by inflammation of the periodontal tissues caused by microorganisms in the oral cavity and affects approximately 90% of the world population. Losses in the alveolar bone and connective tissue are observed due to periodontal diseases, which may lead to tooth loss. In addition, periodontal disease has been associated with many systemic diseases such as coronary artery diseases, stroke, head and neck cancer, pregnancy complications and diabetes. Periodontal disease is affected by risk factors such as smoking and diabetes, similar to vascular diseases. Hence based on above findings the present study was planned for Biochemical and Clinical Evaluation of Correlation of Periodontitis and Early Carotid Atherosclerosis. The present study was planned in Department of Dentistry, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar, India. In the present study 20 cases of the Generalized chronic Periodontitis were enrolled in the Group A as study group patients. And 20 cases of Periodontally healthy individuals were enrolled in Group B as control group patients for comparative evaluation. Under aseptic measures, venous blood samples were drawn by venipuncture in antecubital fossa using 5ml syringe and collected in a plain vacuum tubes and transported to clinical laboratory for lipid profile analysis. Both the groups were subjected for ultrasonography for the assessment of Carotid Intima-Media Thickness (IMT) and Lipid Profile. The data generated from the present study concluded that periodontal disease has association with early carotid atherosclerosis which is a risk factor for cardiovascular diseases .Thus oral health and systemic health are closely related and overall systemic health of an individual can be improved by maintaining a proper oral health regimen. It is important in terms of health policies that there is no need for an additional cost for this early diagnosis. Keywords: Periodontitis, Early Carotid Atherosclerosis, Heart disease, etc.

scholarly journals Study of the influence of different methods of application of Metrogyl Denta gel on the microbiota of periodontal pockets in periodontitis

2021 ◽  
Vol 25 (1) ◽  
pp. 42-47
Author(s):  
Dmitry I. Morozov ◽  
Alexander G. Volkov ◽  
Egor E. Olesov ◽  
Nataliya Zh. Dikopova ◽  
Yulia A. Trefilova
Keyword(s):  
High Frequency ◽  
Periodontal Diseases ◽  
Practical Interest ◽  
Control Group ◽  
Periodontal Tissue ◽  
High Frequency Ultrasound ◽  
Periodontal Tissues ◽  
Group Data ◽  
And Control ◽  
Frequency Ultrasound

BACKGROUND: One of the most popular antibacterial drugs used in periodontology is Metrogil Denta gel. In recent years, it is most often prescribed as a means of local antibacterial therapy. However, there is practically no information about the use of Metrogil Denta gel ultraphonophoresis in the treatment of periodontal tissue diseases. Therefore, the development of the Metrogil Denta gel ultraphonophoresis technique and the study of its effectiveness in inflammatory periodontal diseases has significant theoretical and practical interest. AIM: This study aimed to explore the influence of various methods of using Metrogyl Denta gel on the microbiota of the periodontal pockets in periodontitis. MATERIALS AND METHODS: In the first group (main), composed of 20 patients with a diagnosis of moderate periodontitis, the treatment procedures included high-frequency ultrasound and application of antibacterial preparation of Metrogyl Denta gel for the periodontal tissue (ultraphonophoresis of Metrogyl Denta gel). In the second group (control), composed of 20 patients with a diagnosis of moderate periodontitis, phonophoresis was not prescribed, and Metrogyl Denta gel was applied into the surface of the gums of the upper and lower jaw two times a day for 10 days. RESULTS: Contents of the pathological periodontal pockets were examined twice: first after dental plaque removal in patients with periodontitis of the main and control groups and then after 10 ultraphonophoresis procedures using Metrogyl Denta gel as a contact medium in the study group or after 10 days of Metrogyl Denta gel applications in the control group. Data analysis revealed that ultraphonophoresis of Metrogyl Denta gel has a more pronounced antibacterial effect in comparison with the injection of this drug. CONCLUSIONS: The combined effect of high-frequency ultrasound and Metrogyl Denta gel makes it possible to create a drug reserve in the periodontal tissues.

scholarly journals PERIODONTAL DISEASES AND ATHEROSCLEROSIS (LITERATURE REVIEW)

2019 ◽  
Vol 72 (3) ◽  
pp. 462-465
Author(s):  
Iryna S. Dankevych-Kharchyshyn ◽  
Olena M. Vynogradova ◽  
Natalia V. Malko ◽  
Roman M. Gnid ◽  
Andriana P. Skalat ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Vascular Disease ◽  
Periodontal Diseases ◽  
Disease Diagnosis ◽  
Modern Concept ◽  
Bacterial Invasion ◽  
Periodontal Tissue ◽  
Atherosclerotic Vascular Disease ◽  
Periodontal Tissues ◽  
The Relationship

Introduction: The relationship between periodontal diseases and atherosclerosis is addressed in this article. Both these diseases have an inflammatory basis. Because periodontal disease is a risk factor for developing atherosclerotic vascular disease, diagnosis of the former is important. Particular attention must be paid to patients who have periodontal disease with other risk factors for atherosclerotic vascular disease. Recommendations managing these patients have been made included. The aim: The paper is aimed at familiarization of broad medical public with the presence of the relationship between diseases of periodontal tissues and atherosclerosis. Materials and methods: A thorough comprehensive analysis and generalization of scientific achievements elucidated in the fundamental and periodical publications, relating to diseases of the periodontal tissues and atherosclerosis, has been carried out. Review: The article consists of many researchers regarding the prevalence and intensity of periodontal tissue diseases in people of all ages. Problems associated with the state of periodontal tissues in people under study as dentists and general practitioners. Proven role in the pathogenesis of inflammatory diseases of the periodontal tissues in people with atherosclerosis. In the modern concept of the etiology and pathogenesis of periodontal diseases in people is extremely important role for the immune system and resistance to periodontal bacterial invasion. Analyzed common changes important for pathogenesis of periodontal tissue diseases and atherosclerosis. Conclusions: Consequently, recent studies have shown a clear, directly proportional relationship between periodontal tissue diseases and atherosclerosis, but mechanisms for their development and interaction are not fully disclosed.

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