scholarly journals Clinical signs associated with a case of iatrogenic poisoning by a turpentine-based commercial product in a 3-day-old foal

2020 ◽  
Vol 56 (4) ◽  
pp. e153366
Author(s):  
Abelardo Morales Briceño ◽  
Hilal Al Mahrouqi ◽  
Abdallah Al Kayyoomi ◽  
Harmon Oliva ◽  
Kimberly Brewer ◽  
...  
Keyword(s):  
Anaphylactic Shock ◽  
Clinical Signs ◽  
Vital Signs ◽  
Commercial Product ◽  
Atropine Sulphate ◽  
Severe Respiratory Distress ◽  
Capillary Refill ◽  
Treatment Start ◽  
Mucous Membranes ◽  
Veterinary Product

The aim of this study is to report a case of iatrogenic poisoning by a turpentine-based commercial product in a 3-day-old foal and the successful treatment of this condition. A 3-day-old male foal presented with acute cardio-respiratory collapse, anaphylactic shock, severe respiratory distress, dyspnea and pulmonary edema. The animal’s history included previous administration of a commercial veterinary product (UNITIPAN). Clinical examination revealed: temperature: (39.9 °C), pulse: 135 bpm, respiration: 51 bpm, mucous membranes: moist and congested, capillary refill time: 3 sec or less. The foal was treated with emergency hydration, duphalyte, steroidal anti-inflammatory, atropine sulphate and antibiotic. After 6 h of treatment, the foal was stabilized and vital signs were normalized 8 h after treatment start.

scholarly journals Anaphylactic shock with pulmonary eosinophilic infiltration due to honeybee attack in a donkey: case report

2021 ◽  
Vol 73 (6) ◽  
pp. 1346-1350
Author(s):  
E. Zache ◽  
J.F. Cajueiro ◽  
A.Q. Andrade Neto ◽  
L. Almeida ◽  
R.R. Colares ◽  
...  
Keyword(s):  
Case Report ◽  
Anaphylactic Shock ◽  
Clinical Signs ◽  
Final Diagnosis ◽  
Eosinophilic Infiltration ◽  
Deep Dermis ◽  
Anatomic Pathology ◽  
Subcutaneous Edema ◽  
Mucous Membranes ◽  
Alveolar Edema

ABSTRACT A case of a donkey attacked by Africanized honeybee is reported here with clinical signs of agitation, dehydration, congestion of the ocular mucous membranes, tongue edema, tachycardia and inspiratory dyspnea, and progression to death. At necropsy, diffuse, severe subcutaneous edema at face and cervical regions and severe diffuse pulmonary hyperemia with abundant edema without parenchymal collapse were observed. Microscopically, marked, diffuse deep dermis and panniculus carnosus edema and marked diffuse alveolar edema, with moderate population of eosinophils predominantly around larger caliber vessels were noted. The final diagnosis of anaphylactic shock was supported by history, clinical signs, and anatomic pathology findings. This is the first report of a honeybee attack with pulmonary eosinophilic infiltration in a mammal.

Refractory Anaphylactic Shock Associated with Ketoconazole Treatment

2005 ◽  
Vol 39 (3) ◽  
pp. 547-550 ◽  
Author(s):  
Ping-Yen Liu ◽  
Cheng-Han Lee ◽  
Li-Jen Lin ◽  
Jyh-Hong Chen
Keyword(s):  
Anaphylactic Shock ◽  
Good Condition ◽  
Clinical Signs ◽  
Vital Signs ◽  
High Dose ◽  
Severe Reaction ◽  
Epinephrine Infusion ◽  
Severe Hypotension ◽  
Days Of Therapy ◽  
High Level

OBJECTIVE: To report a rare but severe reaction of refractory anaphylactic shock with ketoconazole treatment—associated hypotensive episodes in an elderly patient. CASE SUMMARY: A 72-year-old woman received antifungal therapy for her almost completely occluded cornea infected with Candida albicans. She was initially prescribed oral ketoconazole 200 mg twice daily. She developed hypotension over the first 2 days of therapy (BP 136/82 mm Hg at baseline; 90/50 mm Hg on day 2). Severe hypotension (BP 90/49 mm Hg) unresponsive to fluid therapy or high-dose dopamine developed on day 4 of therapy. An invasive Swan—Ganz catheterization study showed a very low level of peripheral vascular resistance with high cardiac output index without clinical signs of infection. When laboratory tests showed a high level of plasma tryptase, anaphylactic redistribution shock was diagnosed. Her vital signs became more stable after treatment with hydrocortisone and epinephrine infusion. She was discharged in good condition after 24 hours of observation. DISCUSSION: As of December 2004, refractory anaphylactic shock resulting from ketoconazole use had not been reported. The events of hypotension were strongly associated with the intake of ketoconazole. The hemodynamic results obtained with Swan—Ganz catheterization were compatible with anaphylactic shock. The Naranjo probability scale showed a probable association of the adverse event with ketoconazole. CONCLUSIONS: Ketoconazole may cause severe anaphylactic shock even when taken orally. Invasive catheterization and elevated tryptase levels can provide important information in the management of anaphylactic shock.

scholarly journals Nitrate and nitrite poisoning in sheep and goats caused by ingestion of Portulaca oleracea

2018 ◽  
Vol 38 (8) ◽  
pp. 1549-1553
Author(s):  
João G. Simões ◽  
Rosane Maria T. Medeiros ◽  
Márcia A. Medeiros ◽  
Robério G. Olinda ◽  
Antônio Flávio M. Dantas ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Body Weight ◽  
Clinical Signs ◽  
Portulaca Oleracea ◽  
Sheep And Goats ◽  
Ruminal Ph ◽  
The Third ◽  
Mucous Membranes ◽  
Nitrate And Nitrite ◽  
Positive Results

ABSTRACT: Three outbreaks of poisoning by Portulaca oleracea were reported in sheep and goats in Northeast Brazil. In the first outbreak, 8 out of 20 sheep were affected and later died. In the second outbreak, three goats and one sheep died out of a flock of 30 animals that included both species. In the third outbreak, two out of 19 sheep were affected, and they recovered after a treatment of 2% methylene blue at a dose of 4 mg/kg body weight. In the first and second outbreaks, the animals ingested P. oleracea after it was cut and offered in feeders. In the third outbreak, the flock was grazing in an area that had been invaded by the plant. To determine the toxicity, P. oleracea was administered experimentally at a dose of 80g/kg of body weight to seven sheep, weighing 19-30 kg. One control sheep received green grass. One to four hours after P. oleracea ingestion, the animals showed clinical signs of poisoning characterized by cyanotic mucous membranes, bloat, ruminal pH of 8-9, pollakiuria, aerophagia, involuntary movements of the upper lip, apathy, tachypnea and tachycardia. Five animals recovered, including one that was treated with 1% methylene blue, and two animals died. During necropsy, the mucous membranes were brownish, and the blood was dark brown. Diphenylamine tests of the plant and of rumen contents were positive for nitrates. Positive results for nitrates were also found in 24 samples of P. oleracea that were collected in different places in the states of Pernambuco and Paraíba. We conclude that P. oleracea accumulates nitrates at toxic levels and may cause poisoning in sheep and goats.

scholarly journals Mepivacaine-induced anaphylactic shock in a pregnant woman undergoing combined spinal and epidural anesthesia for cesarean delivery: a case report

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Miyuki Takahashi ◽  
Kunihisa Hotta ◽  
Soichiro Inoue ◽  
Tomonori Takazawa ◽  
Tatsuo Horiuchi ◽  
...  
Keyword(s):  
Case Report ◽  
Cesarean Delivery ◽  
Epidural Anesthesia ◽  
Anaphylactic Shock ◽  
Vital Signs ◽  
Birth Asphyxia ◽  
Causative Factor ◽  
Fetal Heart Rate Monitoring ◽  
Developmental Problems ◽  
Severe Hypotension

Abstract Background Anaphylactic shock during pregnancy is a rare but life-threatening event for both the mother and the newborn. Case presentation A 42-year-old woman, who was pregnant with twins, was scheduled for cesarean delivery under combined spinal and epidural anesthesia. An epidural catheter was placed uneventfully. After spinal anesthesia, the patient exhibited skin symptoms and severe hypotension. The patient was diagnosed with anaphylaxis, and subsequently, treatment was started. Fetal heart rate monitoring revealed sustained bradycardia, and it was decided to proceed with cesarean delivery. After delivery, the mother’s vital signs recovered. Both infants were intubated due to birth asphyxia. Currently, the twins are 4 years old and exhibit no developmental problems. Clinical examination identified mepivacaine as the causative agent of anaphylaxis. Conclusions This case report highlights that upon occurrence of anaphylaxis during pregnancy, maternal treatment and fetal assessment should be started immediately. Indication for immediate cesarean delivery should be considered and a definite identification of the causative factor pursued.

scholarly journals Fatal Onion (Allium Cepa) Toxicosis in Water Buffalo (Bubalus Bubalis)

2009 ◽  
Vol 21 (3) ◽  
pp. 402-405 ◽  
Author(s):  
Vanessa Borelli ◽  
Joelma Lucioli ◽  
Henrique Furlan Fernando ◽  
Giovana Hoepers Patrícia ◽  
Fleck Roveda Juliano ◽  
...  
Keyword(s):  
Allium Cepa ◽  
Water Buffalo ◽  
Clinical Signs ◽  
Epidemiological Data ◽  
Bubalus Bubalis ◽  
Coagulation Necrosis ◽  
Tubular Epithelial Cells ◽  
Dark Urine ◽  
Mucous Membranes ◽  
Renal Tubular

Toxicosis caused by the ingestion of onion ( Allium cepa) by 5 water buffalo ( Bubalus bubalis) occurred in the district of Caçador, Santa Catarina, Brazil. The water buffalo died after ingestion of a large quantity of onion that had been left in the pasture. Clinical signs started 8 days postingestion and were characterized by pale mucous membranes, lethargy, and dark urine. At necropsy, pieces of onions were found in the rumen of 1 animal. The carcass smelled strongly of onion, and the kidneys and urine were dark brown. Microscopic renal lesions included tubular degeneration and necrosis with deposits of eosinophilic material in the cytoplasm of renal tubular epithelial cells and tubular lumina. These changes were consistent with hemoglobinuric nephrosis. Centrilobular coagulation necrosis was observed in the liver accompanied by hemorrhage and macrophages containing brown cytoplasmic pigment. A diagnosis of hemolytic anemia caused by onion toxicosis was based on the epidemiological data, clinical signs, macroscopic changes, and histological lesions.

scholarly journals Efficacy of simethicone for treatment of bloat in ruminants

2017 ◽  
Vol 2 (4) ◽  
pp. 635-638 ◽  
Author(s):  
Mohammad Moshiur Rahman ◽  
Mohammad Musharraf Uddin Bhuiyan ◽  
Md Taohidul Islam ◽  
Mohammed Shamsuddin
Keyword(s):  
Pharmaceutical Company ◽  
Recovery Rate ◽  
Clinical Signs ◽  
Clinical History ◽  
Commercial Product ◽  
Effective Drug ◽  
Veterinary Services ◽  
Community Based ◽  
Commercial Products ◽  
Recovery Rates

The objective of the study was to evaluate the efficacy of simethicone against bloat in ruminants. The investigation was conducted in Potiya Upazila under the Chittagong district where routine veterinary services were in operation by the Community-based Dairy Veterinary Foundation (CDVF), Bangladesh Agricultural University, Mymensingh, Bangladesh. The diagnosis of bloat in animals was done based on clinical history, clinical signs and examination of animals. A total of 90 ruminants (60 cattle, 10 sheep and 20 goats) affected with bloat were treated with simethicone containing two commercial products marketed in Bangladesh (One product such as Bloat Stop®, marketed by ACME Laboratories, Bangladesh and another imported product by other pharmaceutical company). For treatment, 1 gm simethicone in 100 ml solution in cattle and 200 mg simethicone in 20 ml solution in sheep and goats were administered once at a time. The efficacy of simethicone from two commercial products was evaluated on the basis of recovery rate of affected animals. The overall recovery rates in ruminants after treatment with Bloat Stop® and other commercial product were 80% and 76%, respectively. In cattle recovery rate was numerically higher (83%) when treated with commercial product than that of other product (80%). In sheep, recovery rate was numerically higher (80%) when treated with Bloat Stop® than that of imported product (60%). In goats, the recovery rate was 70% after treatment of bloat with both products. However, the recovery rates in ruminant did not differ statistically between two drugs used for treatment of bloat (p>0.05). In conclusion simethicome is an effective drug for clinical treatment of bloat in ruminants.Asian J. Med. Biol. Res. December 2016, 2(4): 635-638

scholarly journals Efficiency of probiotics use in treatment of calves

2020 ◽  
Vol 11 (2) ◽  
pp. 1674-1678
Author(s):  
Nikolay V. Melnik ◽  
Vladimir I. Eremets ◽  
Larisa A. Neminuschaya ◽  
Valentina I. Klyukina ◽  
Svetlana A. Gryn ◽  
...  
Keyword(s):  
Biochemical Analysis ◽  
Clinical Signs ◽  
Feed Additives ◽  
Normal Flora ◽  
Young Stock ◽  
Treatment Start ◽  
Treatment Measures ◽  
Breeding Animal ◽  
Animal Growth ◽  
Positive Effect

The comprehensive approach to solving the issue of the animal raising intensification, the integrated part of which is herd breeding, animal yield preservation and its development provision, conditioned the enhancement of the research works aimed at further investigation of young stock diseases, features of their digestion development, search of efficient preventive and treatment measures, feeds and feed additives for simulating animal growth and development. The main objective of this study was the exploration of comparative therapeutic efficiency of the use of in treatment of calves, in acute digestive disturbances in the complex of conventional treatments. The experiment was carried out in the conditions of Danilovsky Complex of Semenovsky Stud Farm CJSC of Medvedev District in Mari El Republic in calves aged 2-4 days with clinical signs of digestive dysfunction. 3 experimental groups of calves were formed observing the principles of analogues. Calves of the first and the second experimental groups, in addition to the treatment regimen adopted at the farm, were given with milk or milk at the rate of 6 grams and 4 grams, respectively per one calf once a day. and biochemical analysis was carried out in all experimental calves at the beginning of the experiment and 5, 10 and 15 days after the treatment start. The experience demonstrated that has a normalizing effect on protein, carbohydrate, mineral metabolisms, and pH balance. The positive effect of this drug on animals is conditioned by the effect of it selectively stimulates the growth of useful intestinal normal flora by inhibiting pathogenic flora of colon.

scholarly journals Penyakit Ginjal Kronis pada Anjing dan Kucing: Manajemen Terapi dan Diet

2017 ◽  
Vol 35 (1) ◽  
pp. 16
Author(s):  
Yanuartono Yanuartono ◽  
Alfarisa Nururrozi ◽  
Soedarmanto Indarjulianto
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Weight Loss ◽  
Renal Failure ◽  
Renal Function ◽  
Medication Management ◽  
Clinical Signs ◽  
Electrolyte Balance ◽  
Mucous Membranes

Chronic kidney disease is a progressive impairment of renal function and irreversible. The kidneys fail to maintain metabolism and fluid and electrolyte balance, causing uremia. This disease is a common problem in old cats and dogs that not detected by the owners up to 75 % of kidney function is damaged. Clinical signs vary as polyuria, polidipsi, anorexia, vomiting, weight loss, pale mucous membranes, mouth ulceration, halitosis and acute blindness. Chronic renal failure is not curable so that the necessary medication management and proper diet in orderto improve the quality of life and prolong the life of the animal.

scholarly journals What about the others: differential diagnosis of COVID-19 in a German emergency department

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
David Fistera ◽  
Annalena Härtl ◽  
Dirk Pabst ◽  
Randi Manegold ◽  
Carola Holzner ◽  
...  
Keyword(s):  
Emergency Department ◽  
Differential Diagnosis ◽  
Clinical Symptoms ◽  
Respiratory Infections ◽  
Health Care Systems ◽  
Clinical Signs ◽  
Vital Signs ◽  
Main Diagnosis ◽  
Clinical Trial Registry ◽  
Airway Infections

Abstract Background The ongoing COVID-19 pandemic remains a major challenge for worldwide health care systems and in particular emergency medicine. An early and safe triage in the emergency department (ED) is especially crucial for proper therapy. Clinical symptoms of COVID-19 comprise those of many common diseases; thus, differential diagnosis remains challenging. Method We performed a retrospective study of 314 ED patients presenting with conceivable COVID-19 symptoms during the first wave in Germany. All were tested for COVID-19 with SARS-Cov-2-nasopharyngeal swabs. Forty-seven patients were positive. We analyzed the 267 COVID-19 negative patients for their main diagnosis and compared COVID-19 patients with COVID-19 negative respiratory infections for differences in laboratory parameters, symptoms, and vital signs. Results Among the 267 COVID-19 negative patients, 42.7% had respiratory, 14.2% had other infectious, and 11.2% had cardiovascular diseases. Further, 9.0% and 6.7% had oncological and gastroenterological diagnoses, respectively. Compared to COVID-19 negative airway infections, COVID-19 patients showed less dyspnea (OR 0.440; p = 0.024) but more dysgeusia (OR 7.631; p = 0.005). Their hospital stay was significantly longer (9.0 vs. 5.6 days; p = 0.014), and their mortality significantly higher (OR 3.979; p = 0.014). Conclusion For many common ED diagnoses, COVID-19 should be considered a differential diagnosis. COVID-19 cannot be distinguished from COVID-19 negative respiratory infections by clinical signs, symptoms, or laboratory results. When hospitalization is necessary, the clinical course of COVID-19 airway infections seems to be more severe compared to other respiratory infections. Trial registration: German Clinical Trial Registry DRKS, DRKS-ID of the study: DRKS00021675 date of registration: May 8th, 2020, retrospectively registered.

scholarly journals Design and monitoring body temperature and heart rate in humans based on WSN using star topology

2021 ◽  
Vol 22 (1) ◽  
pp. 326
Author(s):  
Setiyo Budiyanto ◽  
Freddy Artadima Silaban ◽  
Lukman Medriavin Silalahi ◽  
Selamet Kurniawan ◽  
Fajar Rahayu I. M. ◽  
...  
Keyword(s):  
Heart Rate ◽  
Body Temperature ◽  
Success Rate ◽  
Medical Information ◽  
Human Life ◽  
Clinical Signs ◽  
Vital Signs ◽  
Pulse Sensor ◽  
Information And Communication ◽  
Rate Sensor

<span><span>Electronic health (E-health) uses information and communication technology including electronics, telecommunications, computers, and informatics to process various types of medical information, to carry out clinical services (diagnosis or therapy). Health is the most important asset in human life, therefore maintaining health is a top priority and serious attention needed. Heart rate and body temperature are vital signs that the hospital routinely checks for clinical signs and are useful for strengthening the diagnosis of a disease. In this research monitoring heart rate and body temperature with the wireless sensor network (WSN) method that uses <span>NodeMCU 1.0 as a controller module and wireless as communication between nodes, the wireless network used in this research Wi-Fi network. As a data taker, a DS18b20 temperature sensor and a heart rate sensor (pulse sensor) are needed, which will be displayed by the ThingSpeak web and smartphones. From the test results, the success rate of the system in detecting heart rates is 97.17%. Whereas in detecting body temperature the success rate of the system is 99.28%. For data transmission, the system can send data smoothly at a maximum distance of 15 meters with a barrier.</span></span></span>

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