Abstract P070: Longer Sleep Duration Is Associated With Less Myosteatosis In African Caribbean Adults

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Adrianna I Acevedo-Fontanez ◽  
Ryan Cvejkus ◽  
Allison L Kuipers ◽  
Joseph Zmuda ◽  
Victor Wheeler ◽  
...  
Keyword(s):  
Physical Activity ◽  
Skeletal Muscle ◽  
Sleep Duration ◽  
Vigorous Physical Activity ◽  
Health Study ◽  
Muscle Area ◽  
Subjective Data ◽  
Muscle Density ◽  
Intermuscular Adipose Tissue ◽  
African Caribbean

Introduction: Skeletal muscle is the largest organ in the human body and vital to maintaining metabolic homeostasis. Increased skeletal muscle fat infiltration (i.e. myosteatosis) is now recognized as a major risk factor for cardio-metabolic diseases, independent of general obesity. Modifications in lifestyle, such as sleep, to reduce myosteatosis would be of great public health importance. However, studies of this relationship often use subjective data and are lacking in minority populations. The aim of this study was to examine the relation between objectively measured sleep duration and myosteatosis at the calf among African Caribbeans. Methods: Data were collected on men (n=393) and women (n=438) from the Tobago Health Study. Sleep duration and physical activity was collected using a SenseWear Pro Armband (BodyMedia, Inc.). Participants were instructed to wear the armband at all times, except in water, for 4-7 days. Measures of muscle density, intermuscular adipose tissue (IMAT), and area were obtained by peripheral QCT scans of the calf (Stratec XCT-2000). Model covariates included age, sex, BMI, diabetes, alcohol intake, smoking, and moderate to vigorous physical activity (MVPA). Linear regression was used to assess the relationship of sleep duration on skeletal muscle. Results: Mean sleep duration was 5.5 hours/day (Min 2.2, Max 11.6). Overall, participants were aged 58.7 years, had a BMI of 30.2 kg/m 2 , spent an average of 42 min/day in MVPA, and 18% were diabetic. In fully adjusted models, longer sleep duration was associated with smaller muscle area, but greater muscle density and less IMAT (all P<0.03). There was no interaction of sleep and sex on muscle density, area and IMAT (p-value=0.5184; 0.2730; 0.0954). Conclusions: In African Caribbean men and women, longer sleep duration was associated with less myosteatosis, as well as, less muscle area at the calf. Further research is warranted to understand this relationship longitudinally in order to determine how it may inform lifestyle guidelines in the Caribbean.

Physical Activity, Sedentary Time, and Sleep and the Association With Inflammatory Markers and Adiponectin in 8- to 11-Year-Old Danish Children

2016 ◽  
Vol 13 (7) ◽  
pp. 733-739 ◽  
Author(s):  
Mette S. Nielsen ◽  
Jonas S. Quist ◽  
Jean-Philippe Chaput ◽  
Stine-Mathilde Dalskov ◽  
Camilla T. Damsgaard ◽  
...  
Keyword(s):  
Physical Activity ◽  
Sleep Duration ◽  
Inflammatory Markers ◽  
Sedentary Time ◽  
Vigorous Physical Activity ◽  
Movement Behavior ◽  
Inverse Association ◽  
Pubertal Status ◽  
Negatively Associated ◽  
Reactive Protein

Background:Inflammatory markers, adiponectin, and movement/nonmovement behaviors have all been linked to risk factors for cardiovascular disease; however, the association between childhood movement/nonmovement behaviors and inflammatory markers and adiponectin is unknown.Methods:We explored the association between accelerometer determined moderate-to-vigorous physical activity (MVPA), sedentary time, and sleep (7 days/8 nights) and fasting C-reactive protein (CRP), interleukin-6 (IL-6), and adiponectin in 806 school children. A sleep variability score was calculated.Results:MVPA was negatively associated with adiponectin in boys and girls (P < .001) and with CRP and IL-6 in girls (P < .05) independent of sleep duration, sedentary time, age, fat mass index (FMI), and pubertal status. Sedentary time was positively associated with adiponectin in boys and girls (both P < .001), and sleep duration with adiponectin in boys independent of age, FMI, and pubertal status (P < .001); however, these associations disappeared after mutual adjustments for movement behavior. Sleep duration variability was positively associated with CRP in girls independent of all covariates (P < .01).Conclusion:MVPA remained negatively associated with inflammatory markers and adiponectin, and sleep duration variability positively associated with CRP after adjustment for FMI, pubertal status, and other movement behavior. The inverse association between MVPA and adiponectin conflicts with the anti-inflammatory properties of adiponectin.

Abstract P463: Objectively Measured Moderate-to-Vigorous Physical Activity is Associated With Decreased Myosteatosis in African Caribbean Adults

Circulation ◽  
2020 ◽  
Vol 141 (Suppl_1) ◽  
Author(s):  
Iva Miljkovic ◽  
Allison Kuipers ◽  
Ryan Cvejkus ◽  
Victor Wheeler ◽  
Joseph Zmuda
Keyword(s):  
Physical Activity ◽  
Skeletal Muscle ◽  
Sedentary Behavior ◽  
Metabolic Diseases ◽  
Vigorous Physical Activity ◽  
Middle Aged ◽  
Fat Infiltration ◽  
Muscle Attenuation ◽  
Muscle Fat Infiltration ◽  
Objectively Measured

Increased skeletal muscle fat infiltration (i.e. myosteatosis) is now recognized as a major risk factor for cardio-metabolic diseases. Therefore, a lifestyle modification that reduces myosteatosis would be of great public health importance. However, studies examining the association of relevant lifestyle factors with this ectopic fat depot are lacking, particularly in African ancestry populations who have a very high burden of cardio-metabolic diseases. The aim of this study was to examine the relation between objectively measured physical activity and sedentary behavior with computed tomography measured calf muscle attenuation among middle-aged and elderly African-Caribbeans from the population-based Tobago Health Study. Preliminary analyses were conducted among 134 women (mean age 59 yrs, mean BMI 31.6 kg/m 2 ) and 355 men (mean age 62 yrs, mean BMI 28 kg/m 2 ). Physical activity was measured using the SenseWear Pro armband worn for 4-7 days. We calculated the mean duration of waking time engaged in light physical activity (LPA), moderate to vigorous activity (MVPA), and sedentary behavior (SB) per day. Skeletal muscle attenuation (mg/cm 3 ) reflects the fat content of the muscle such that greater skeletal muscle fat infiltration is reflected by lower attenuation. Women spent less time in LPA (146 vs. 270 min/day) and MVPA (15 vs. 41 min/day), but more time in SB (789 vs. 647 min/day) than men (all p<0.0001) after adjustments for gender differences in age. Muscle attenuation was lower among women compared with men (70.5 vs. 72.7 mg/cm3; age and BMI adjusted p<0.0001). In both women and men, muscle attenuation was positively correlated with the LPA and MVPA, and inversely with time spent in SB (spearman correlation coefficients (r) ranged from 0.21 to 0.39, all p<0.006 adjusted for age). Upon additional adjustment for BMI, in both women and men, the association of muscle attenuation with MVPA remained significant (r=0.21 and r=0.18, respectively, both p<0.03), but there was no association with LPA. Percent time spent in SB was associated with muscle attenuation only among women after additional adjustment for BMI (women: -0.16, p=0.052), and we also found a significant sex interaction effect of SB on muscle attenuation (p=0.035). Our preliminary findings suggest that there is significant association between MVPA and myosteatosis among middle-aged and elderly African Caribbeans. However, SB may only be relevant for myosteatosis among women. Future analyses will be conducted in a larger sample from this cohort to confirm our findings and to test for independence from other potential confounding factors, such as diet, sleep patterns, adiposity distribution, and diabetes.

Effect of exercise on sleep and bi-directional associations with accelerometer-assessed physical activity in men with obesity

2020 ◽  
Author(s):  
Tatiana Plekhanova ◽  
Alex V. Rowlands ◽  
Melanie Davies ◽  
Charlotte L. Edwardson ◽  
Andrew Hall ◽  
...  
Keyword(s):  
Physical Activity ◽  
Sleep Quality ◽  
Aerobic Exercise ◽  
Sleep Duration ◽  
Exercise Intervention ◽  
Vigorous Physical Activity ◽  
Sleep Onset ◽  
Onset Time ◽  
Post Intervention

This study examined the effect of exercise training on sleep duration and quality and bidirectional day-to-day relationships between physical activity (PA) and sleep. Fourteen inactive men with obesity (49.2±7.9 years, BMI 34.9±2.8 kg/m²) completed a baseline visit, eight-week aerobic exercise intervention, and one-month post-intervention follow-up. PA and sleep were assessed continuously throughout the study duration using wrist-worn accelerometry. Generalised estimating equations (GEE) were used to examine associations between PA and sleep. Sleep duration increased from 5.2h at baseline to 6.6h during the intervention period and 6.5h at one-month post-intervention follow-up (p<0.001). Bi-directional associations showed that higher overall activity volume and moderate-to-vigorous physical activity (MVPA) were associated with earlier sleep onset time (p<0.05). Later timing of sleep onset was associated with lower overall volume of activity, most active continuous 30 minutes (M30CONT), and MVPA (p<0.05). Higher overall activity volume, M30CONT, and MVPA predicted more wake after sleep onset (WASO) (p<0.001), whereas greater WASO was associated with higher overall volume of activity, M30CONT, and MVPA (p<0.001). An aerobic exercise intervention increased usual sleep duration. Day-to-day, more PA predicted earlier sleep onset, but worse sleep quality and vice versa. Novelty: • Greater levels of physical activity in the day were associated with an earlier sleep onset time that night, whereas a later timing of sleep onset was associated with lower physical activity the next day in men with obesity • Higher physical activity levels were associated with worse sleep quality, and vice versa

scholarly journals Observed Physical Function Is Associated With Better Cognition Among Elderly Adults: The Adventist Health Study-2

2020 ◽  
Vol 35 ◽  
pp. 153331752096086 ◽  
Author(s):  
Nicole M. Gatto ◽  
Jennifer Garcia-Cano ◽  
Crissy Irani ◽  
Tiantian Liu ◽  
Cameron Arakaki ◽  
...  
Keyword(s):  
Physical Activity ◽  
Physical Function ◽  
Dietary Patterns ◽  
Processing Speed ◽  
Performance Test ◽  
Vigorous Physical Activity ◽  
Health Study ◽  
Elderly Adults ◽  
Timed Up And Go ◽  
Speed Factor

Lifestyle factors may individually protect against the development of mild cognitive impairment. We investigate the relationships between both self-reported physical activity and measured physical function with cognition in a population of elderly adults, more than half of whom follow vegetarian dietary patterns. Otherwise healthy adults (n = 127, mean age 74.9 ± 7.9 years, 61.3% current vegetarians) were assessed using a comprehensive neuropsychological battery. A principal components analysis derived processing speed, executive function, and memory/language factors. Participants reported current levels of vigorous physical activity on questionnaires, and physical function and mobility were measured with the Physical Performance Test (PPT) and Timed Up and Go (TUG) Test. Generalized linear models estimated β coefficients for cross-sectional associations between cognitive factors and indicators of physical abilities and self-reported physical activity. Better physical function indicated by PPT was associated with higher scores on the processing speed factor (β = 0.21 SDs for each 4.4-point increase in PPT score; p = 0.02). Faster TUG times were also associated with higher processing speed factor scores (β = 0.21 SDs increase for each 2.8 second less TUG time; p = 0.02). Self-reported levels of vigorous physical activity were not associated with any area of cognitive function; the association between PPT, TUG and processing speed was independent of physical activity. Associations between PPT and TUG and processing speed were stronger among participants who followed vegetarian dietary patterns. Better physical function may have an effect on cognition in a context of healthy lifestyles.

The relationship between sleep and physical activity: The moderating role of daily alcohol consumption

SLEEP ◽  
2021 ◽  
Author(s):  
Eunjin Lee Tracy ◽  
Kathryn Jean Reid ◽  
Kelly Glazer Baron
Keyword(s):  
Physical Activity ◽  
Alcohol Consumption ◽  
Sleep Duration ◽  
Alcohol Intake ◽  
Vigorous Physical Activity ◽  
Sleep Onset ◽  
Sleep Fragmentation ◽  
Activity Duration ◽  
Alcoholic Drinks ◽  
Physical Activity Duration

Abstract Study objectives Studies have demonstrated a daily, bidirectional relationship between sleep and physical activity. However, little is known about how other health behaviors, such as alcohol consumption affect this relationship. This study examined how daily and average alcohol consumption affects the relationships between sleep and physical activity. Methods Participants included 70 men and women, ages 18-50 with sleep duration &gt;6.5 h. Participants wore an actigraph, physical activity monitor and recorded number of alcoholic drinks by daily food logs for 7 days. Results were analyzed using multi-level models to evaluate the 7-day average (i.e., between-person effects) and daily effects (i.e., within-person effects) simultaneously. Results Those with more average (7 day) minutes of vigorous physical activity had less wake after sleep onset (WASO). Furthermore, a higher number of alcoholic drinks was associated with longer sleep duration and higher WASO over 7 days. Days with a higher number of alcoholic drinks were associated with higher WASO and sleep fragmentation that night. Alcohol intake moderated the average (7 day) and daily relationships between sleep and physical activity such that high average (7 days) WASO was associated with shorter average total physical activity duration, but only for those with higher alcohol intake. In addition, longer physical activity duration during the day was associated with lower sleep fragmentation that night, but only for those with lower alcohol intake. Conclusions These data demonstrate that in a naturalistic setting, alcohol intake negatively impacts sleep and diminishes the benefits of physical activity on sleep.

Polar Vantage and Oura physical activity and sleep trackers: A validation and comparison study (Preprint)

2021 ◽  
Author(s):  
André Henriksen ◽  
Frode Svartdal ◽  
Sameline Grimsgaard ◽  
Gunnar Hartvigsen ◽  
Laila Hopstock
Keyword(s):  
Physical Activity ◽  
Heart Rate ◽  
Energy Expenditure ◽  
Total Energy ◽  
Sleep Duration ◽  
Vigorous Physical Activity ◽  
Total Energy Expenditure ◽  
Sleep Diary ◽  
Resting Heart Rate ◽  
Activity Trackers

BACKGROUND Consumer-based activity trackers are increasingly used in research as they have potential to increase activity participation and can be used for estimating physical activity. However, the accuracy of newer consumer-based devices is mostly unknown, and validation studies are needed. OBJECTIVE The objective of this study was to test the accuracy of the Polar Vantage watch and Oura ring activity trackers for measuring physical activity, total energy expenditure, resting heart rate, and sleep duration, in free-living adults. METHODS Twenty-one participants wore two consumer-based activity trackers (Polar, Oura), an ActiGraph accelerometer, an Actiheart accelerometer and heart rate monitor, and completed a sleep diary for up to seven days. We assessed Polar and Oura validity and comparability for physical activity, total energy expenditure, resting heart rate (Oura), and sleep duration. We analysed repeated measures correlation, Bland-Altman plots, and mean absolute percentage error. RESULTS Polar and Oura were both strongly correlated (p<0.001) with ActiGraph for steps (Polar r 0.75, 95% CI 0.54-0.92. Oura r 0.77, 95% CI 0.62-0.87), moderate-to-vigorous physical activity (Polar r 0.76, 95% CI 0.62-0.88. Oura r 0.70, 95% CI 0.49-0.82), and total energy expenditure (Polar r 0.69, 95% CI 0.48-0.88. Oura r 0.70, 95% CI 0.51-0.83) and strongly or very strongly correlated (p<0.001) with the sleep diary for sleep duration (Polar r 0.74, 95% CI 0.56-0.88. Oura r 0.82, 95% CI 0.68-0.91). Oura had a very strong correlation (p<0.001) with Actiheart for resting heart rate (r 0.9, 95% CI 0.85-0.96). However, all confidence interval ranges were wide and mean absolute percentage error was high for all variables, except Oura sleep duration (10%) and resting heart rate (3%) where Oura under-reported on average one beat per minute. CONCLUSIONS Oura can potentially be used as an alternative to Actiheart to measure resting heart rate. For sleep duration, Polar and Oura can potentially be used as a replacement for a manual sleep diary, depending on acceptable error. Neither Polar nor Oura can replace ActiGraph for measuring steps, moderate-to-vigorous physical activity, and total energy expenditure, but may be used as an additional source of physical activity in some settings.

scholarly journals Moderate to vigorous physical activity and impact loading independently predict variance in bone strength at the tibia but not at the radius in children

2019 ◽  
Vol 44 (3) ◽  
pp. 326-331 ◽  
Author(s):  
Anthony M. Kehrig ◽  
Kelsey M. Björkman ◽  
Nazeem Muhajarine ◽  
James D. Johnston ◽  
Saija A. Kontulainen
Keyword(s):  
Physical Activity ◽  
Bone Strength ◽  
Vigorous Physical Activity ◽  
Quantitative Computed Tomography ◽  
Peripheral Quantitative Computed Tomography ◽  
Children And Youth ◽  
Strength Development ◽  
Linear Regression Models ◽  
Muscle Area ◽  
Objective Recording

The objectives of this study were (i) to assess whether daily minutes of moderate to vigorous physical activity (MVPA) or vigorous physical activity (VPA) and impact counts (acceleration peaks ≥3.9g) independently predict variance in bone strength in children and youth and (ii) to estimate bone strength gain associated with increases in daily MVPA, VPA, or impact counts. We recorded 7-day activity of 49 participants (mean age 11.0 years, SD 1.7) using accelerometers and estimated radius and tibia bone strength using peripheral quantitative computed tomography. We used linear regression models adjusted for sex, body mass, and muscle area to address our objectives. Daily MVPA (mean 50 min, SD 23) and VPA (mean 17 min, SD 11) or impacts (mean 71 counts, SD 59) did not predict variance in radius strength. Daily VPA (β = 0.24) predicted variance in tibia strength at the distal and shaft sites, and shaft strength was also predicted by MVPA (β = 0.20) and impact counts (β = 0.21). Our models estimated a 3%–6%, 4%, or 4%–11% gain in tibia strength after increasing daily MVPA by 10–20 min, VPA by 5 min, or impacts by 30–100 counts, respectively. In conclusion, daily minutes of MVPA or VPA and impact counts are independent predictors of tibia but not radius strength. Objective recording of activities associated with forearm bone strength and trials testing the efficacy of increasing daily MVPA, VPA, and related impacts on bone strength development in children and youth are warranted.

Sign in / Sign up

Export Citation Format

Share Document