Abstract 174: The Longitudinal Effect of Medicaid Expansion on 30-Day Readmissions for Heart Failure and Acute Myocardial Infarction - Insights from Hospital Compare

Author(s):  
Ankeet S Bhatt ◽  
Azalea Kim ◽  
William K Bleser ◽  
Robert Saunders ◽  
Zubin J Eapen

Background: The emergency department (ED) is a primary access point for hospital admissions/ readmissions. Recent analyses have found that state-level Medicaid expansion is associated with higher ED volumes and longer ED length of stay (LOS). Increased ED congestion has been proposed to lead to higher readmission rates, though this has not been empirically evaluated. We examined the association of Medicaid expansion with readmission rates for AMI and HF specifically given that these readmissions are prevalent, publicly reported, and subject to financial penalties. Methods: We utilized the Hospital Compare database to construct a panel of US acute care hospitals offering ED services over three time intervals: 10/01/2012-09/30/2013, before any Medicaid expansion effective coverage dates (“Period 1”); 10/1/2013-9/30/2014 and 10/1/2014-9/30/2015, after Medicaid expansion effective coverage dates (“Periods 2 and 3”). We used multivariate linear fixed-effects regression to evaluate the independent effect of Medicaid expansion on absolute unplanned 30-day case-mix adjusted readmission rates for AMI and HF. Fixed effects regression adjusts for time-invariant confounders by design and potential time-variant confounders were included as covariates, including year fixed effects to control for temporal variation. Standard errors were clustered on states. Sensitivity analysis was performed to evaluate the interaction between Medicaid expansion and ED LOS with respect to the primary outcome. Results: Our model examined 2,257 hospitals for AMI and 2,947 hospitals for HF. Overall, within-hospital 30-day unplanned readmission rates for AMI and HF decreased over the three defined periods. AMI readmission rates decreased by 1.37% (95% CI: -1.46% to -1.27%) from Period 1 to Period 3. HF readmission rates decreased by 1.07% (95% CI: -1.21% to -0.93%) from Period 1 to Period 3. All p-values were <0.001. Medicaid expansion effective coverage dates did not affect within-hospital readmissions rates for AMI (ARR -0.09%; 95% CI: -0.22% to 0.04%; p-value 0.162) or HF (ARR -0.03%; 95% CI: -0.20 to 0.15%; p-value 0.770). A sensitivity analysis showed no interaction between Medicaid expansion and ED LOS with respect to the primary outcome (p value = 0.190 for AMI, p-value = 0.255 for HF). Conclusion: Among hospitals with publicly reported outcomes in the Hospital Compare database, readmission rates for AMI and HF decreased from 2012-2015. Medicaid expansion was not associated with significant within-hospital differences in 30-day readmission rates for AMI and HF. There was no interaction by ED LOS. Our results offer evidence to quell concerns that Medicaid expansion, by increasing ED LOS, may adversely impact unplanned readmission rates. Further studies are needed to evaluate factors affecting within-hospital readmission rates.

Author(s):  
Soumya Upadhyay ◽  
Amber L. Stephenson ◽  
Dean G. Smith

This longitudinal study examines whether readmission rates, made transparent through Hospital Compare, affect hospital financial performance by examining 98 hospitals in the State of Washington from 2012 to 2014. Readmission rates for acute myocardial infarction (AMI), pneumonia (PN), and heart failure (HF) were examined against operating revenues per patient, operating expenses per patient, and operating margin. Using hospital-level fixed effects regression on 276 hospital year observations, the analysis indicated that a reduction in AMI readmission rates is related with increased operating revenues as expenses associated with costly treatments related with unnecessary readmissions are avoided. Additionally, reducing readmission rates is related with an increase in operating expenses. As a net effect, increased PN readmission rates may show marginal increase in operating margin because of the higher operating revenues due to readmissions. However, as readmissions continue to happen, a gradual increase in expenses due to greater use of resources may lead to decreased profitability.


2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Zahra Anjoman Azari ◽  
Mojgan Mirghafourvand ◽  
Ciara Hughes ◽  
Shiva Havizari

Context: Constipation is a prevalent symptom of gastrointestinal disorders, which has an annoying impact on health and quality of life. On the other hand, reflexology is a popular type of complementary and alternative medicine in medical practices. Objectives: The present study aimed to assess the effect of foot reflexology on constipation symptoms. Methods: Nine databases were systematically searched to detect relevant Randomized Clinical Trials. The current used the Cochrane Risk of Bias tool to evaluate the methodological quality of the included articles. The primary outcome was the improvement of constipation symptoms. The Standardized Mean Difference (SMD) was measured, and random effects were reported instead of the fixed effects due to the high heterogeneity. Results: Out of the 693 articles retrieved from the databases and eight additional records identified through other sources, 496 titles, 48 abstracts, and 16 full-texts were reviewed, and 11 articles were included in this study, out of which nine articles entered the meta-analysis. The findings of the meta-analysis indicated that foot reflexology had a significant effect on the constipation score (SMD: -0.82; 95% CI: -1.47 to -0.17; P value = 0.0001; I2 = 93%) Conclusions: Foot reflexology can effectively improve constipation symptoms; however, clinical trials with better designs are recommended.


PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0256406
Author(s):  
Francisco Perez-Arce ◽  
Marco Angrisani ◽  
Daniel Bennett ◽  
Jill Darling ◽  
Arie Kapteyn ◽  
...  

Background The COVID-19 pandemic brought about large increases in mental distress. The uptake of COVID-19 vaccines is expected to significantly reduce health risks, improve economic and social outcomes, with potential benefits to mental health. Purpose To examine short-term changes in mental distress following the receipt of the first dose of the COVID-19 vaccine. Methods Participants included 8,003 adults from the address-based sampled, nationally representative Understanding America Study (UAS), surveyed at regular intervals between March 10, 2020, and March 31, 2021 who completed at least two waves of the survey. Respondents answered questions about COVID-19 vaccine status and self-reported mental distress as measured with the four-item Patient Health Questionnaire (PHQ-4). Fixed-effects regression models were used to identify the change in PHQ-4 scores and categorical indicators of mental distress resulting from the application of the first dose of the COVID-19 vaccine. Results People who were vaccinated between December 2020 and March 2021 reported decreased mental distress levels in the surveys conducted after receiving the first dose. The fixed-effects estimates show an average effect of receiving the vaccine equivalent to 4% of the standard deviation of PHQ-4 scores (p-value<0.01), a reduction in 1 percentage point (4% reduction from the baseline level) in the probability of being at least mildly depressed, and of 0.7 percentage points (15% reduction from the baseline level) in the probability of being severely depressed (p-value = 0.06). Conclusions Getting the first dose of COVID-19 resulted in significant improvements in mental health, beyond improvements already achieved since mental distress peaked in the spring of 2020.


Blood ◽  
2019 ◽  
Vol 134 (Supplement_1) ◽  
pp. 4950-4950
Author(s):  
Ahmad Abu-Hashyeh ◽  
Saad Ullah Malik ◽  
Jennifer Dotson ◽  
Abdul Mughees Rana ◽  
Warda Faridi ◽  
...  

Background Stroke is one of the leading causes of death in the United States and carries a significant risk of morbidity and mortality. P2Y12 inhibitors (Clopidogrel, Ticagrelor etc.) as monotherapy or in combination are used to decrease risk of future ischemic strokes. While standard dosing regimens are currently being used ,the effect of obesity on their efficacy remains unclear. We examined the effect of obesity on the efficacy of P2Y12 inhibitors compared to controls in preventing future incidence of ischemic stroke. Methods We conducted a systematic search on Pubmed, Embase, Cochrane Library, Cochrane Central Register of Controlled Trials and Web of Science to identify relevant randomized clinicals (RCTs) until 31st, July 2019. Our primary outcome of interest was to assess the efficacy of P2Y12 inhibitors (Clopidogrel and Ticagrelor) in preventing recurrent stroke among obese patients with recent stroke or obese individuals at high risk for atherothrombotic events. Obesity was defined as body mass index (BMI) >30kg/m2 and normal BMI was defined as 18 kg/m2 to 25kg/m2. Collected data included dosing regimens, hazard ratio (HR) and confidence interval (CI) for primary outcome in each study arm. We used DerSimonian and Laird random-effects model to estimate pooled HR along with 95% CI using Comprehensive Meta Analysis (CMA) version 3.3. We also performed a sensitivity analysis of the RCTs using Clopidogrel. Heterogeneity was assessed using I2 statistic (<25%=negligible, 25% to 50%= moderate, ≥70% =substantial). Publication bias was assessed using funnel plot and risk of bias was assessed using Grading of Recommendations Assessment, Development and Evaluation (GRADE) tool for clinical trials. Results Out of 2142 studies initially retrieved, we included three RCTS (n=49134) namely CHARISMA (clopidogrel (Clopi) plus asprin (ASA) vs ASA), PRoFESS (Clopi vs ASA plus dipyridamole (Dipy), and SOCRATES (ticagrelor (Tica) vs ASA). There was no statistical difference in the efficacy of P2Y12 inhibitors in preventing stroke when obese and normal BMI patients were compared (p-value of interaction = 0.80, HR: 0.97 [95% CI: 0.88-1.06]) (figure 1). Sensitivity analysis of patients using Clopi also revealed no statistical difference in preventing future stroke (p-value of interaction = 0.96, HR: 1.03 [95% CI: 0.91-1.16]) (figure 2) in obese vs normal BMI patients. Moreover, there was no difference in the efficacy of P2Y12 inhibitors vs control arm (HR: 0.98 [95% CI: 0.85-1.13], p-value: 0.81, I2=0%) and Clopidogrel only vs Control arm (HR: 1.03 [95% CI: 0.88-1.20], p-value: 0.75, I2=0%) in preventing stroke among obese patients. Conclusion Although Obesity is a known risk factor for cardiovascular events including stroke, and it affects the metabolism of many drugs including anticoagulants among others which was the basis of the idea to look into the published literature on the topic in an attempt to find a correlation between obesity and an increased risk of stroke in patients on P2Y12 inhibitors, there was no difference in the efficacy of standard dose P2Y12 inhibitors in obese patients as compared to normal BMI patients. Sensitivity analysis of trials using standard dose Clopidogrel also revealed no statistical difference, we believe the topic might benefit from further studies . Disclosures Anwer: Seattle Genetics: Membership on an entity's Board of Directors or advisory committees; In-Cyte: Speakers Bureau.


2021 ◽  
Vol 9 (1) ◽  
Author(s):  
Xiao-Li Chen ◽  
Bei-Lei Zhang ◽  
Chang Meng ◽  
Hui-Bin Huang ◽  
Bin Du

Abstract Objective Conservative oxygen strategy is recommended in acute illness while its benefit in ICU patients remains controversial. Therefore, we sought to conduct a systematic review and meta-analysis to examine such oxygen strategies’ effect and safety in ICU patients. Methods We searched PubMed, Embase, and the Cochrane database from inception to Feb 15, 2021. Randomized controlled trials (RCTs) that compared a conservative oxygen strategy to a conventional strategy in critically ill patients were included. Results were expressed as mean difference (MD) and risk ratio (RR) with a 95% confidence interval (CI). The primary outcome was the longest follow-up mortality. Heterogeneity, sensitivity analysis, and publication bias were also investigated to test the robustness of the primary outcome. Results We included seven trials with a total of 5265 patients. In general, the conventional group had significantly higher SpO2 or PaO2 than that in the conservative group. No statistically significant differences were found in the longest follow-up mortality (RR, 1.03; 95% CI, 0.97–1.10; I2=18%; P=0.34) between the two oxygen strategies when pooling studies enrolling subjects with various degrees of hypoxemia. Further sensitivity analysis showed that ICU patients with mild-to-moderate hypoxemia (PaO2/FiO2 >100 mmHg) had significantly lower mortality (RR, 1.24; 95% CI, 1.05–1.46; I2=0%; P=0.01) when receiving conservative oxygen therapy. These findings were also confirmed in other study periods. Additional, secondary outcomes of the duration of mechanical ventilation, the length of stay in the ICU and hospital, change in sequential organ failure assessment score, and adverse events were comparable between the two strategies. Conclusions Our findings indicate that conservative oxygen therapy strategy did not improve the prognosis of the overall ICU patients. The subgroup of ICU patients with mild to moderate hypoxemia might obtain prognosis benefit from such a strategy without affecting other critical clinical results.


2021 ◽  
pp. 0192513X2098556
Author(s):  
Karsten Hank

Despite the important role of adult parent–child and sibling relations in the family system, only few studies have investigated yet, how the common adult experience of parental death impacts sibling relations. Estimating fixed-effects regression models using four waves of data from the German Family Panel (pairfam; n = 4,123 respondents), the present note focused on changes in three dimensions of adult siblings’ relationship qualities following the first parent’s death. Our analysis revealed a short-term positive effect of parental death on sibling contacts as well as longer-lasting increases in emotional closeness and conflicts. Next to an intensification of sibling relations following the first parent’s death, we also detected significant spillover effects from respondents’ relationship with the surviving parent to their sibling relations. Our analysis thus provided evidence for adult parent–child and sibling relations to be “linked in life and death,” underlining the benefits of jointly analyzing intra- and intergenerational family relationships.


Author(s):  
Cody A Drolc ◽  
Lael R Keiser

Abstract Government agencies often encounter problems in service delivery when implementing public programs. This undermines effectiveness and raise questions about accountability. A central component of responsiveness and performance management is that agencies correct course when problems are identified. However, public agencies have an uneven record in responding to problems. In this paper we investigate whether, and to what extent, capacity both within the agency and within institutions performing oversight, improves agency responsiveness to poor performance indicators. Using panel data on eligibility determinations in the Social Security Disability program from U.S. state agencies from 1991-2015 and fixed effects regression, we find that indicators of agency and oversight capacity moderate the relationship between poor performance and improvement. Our results suggest that investments in building capacity not only within agencies, but also within elected institutions, are important for successful policy implementation. However, we find evidence that while agency capacity alone can improve responsiveness to poor performance, the effect of oversight capacity on improving performance requires high agency capacity.


2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 76-76
Author(s):  
Kylie Meyer ◽  
Zachary Gassoumis ◽  
Kathleen Wilber

Abstract Caregiving for a spouse is considered a major stressor many Americans will encounter during their lifetimes. Although most studies indicate caregiving is associated with experiencing diminished health outcomes, little is known about how this role affects caregivers’ use of acute health services. To understand how spousal caregiving affects the use of acute health services, we use data from the Health and Retirement Study. We apply fixed effects (FE) logistic regression models to examine odds of experiencing an overnight hospitalization in the previous two years according to caregiving status, intensity, and changes in caregiving status and intensity. Models controlled for caregiver gender, age, race, ethnicity, educational attainment, health insurance status, the number of household residents, and self-assessed health. Overall, caregivers were no more likely to experience an overnight hospitalization compared to non-caregivers (OR 0.92; CI 0.84 to 1.00; p-value=0.057). However, effects varied according to the intensity of caregiving and the time spent in this role. Compared to non-caregivers, for example, spouses who provided care to someone with no need for assistance with activities of daily living had lower odds of experiencing a hospitalization (OR 0.77; CI 0.66 to 0.89). In contrast, caregivers who provided care to someone with dementia for 4 to &lt;6 years had 3.29 times the odds of experiencing an overnight hospitalization (CI 1.04 to 10.38; p-value=0.042). Findings indicate that, although caregivers overall appear to use acute health services about as much as non-caregivers, large differences exist between caregivers. Results emphasize the importance of recognizing diversity within caregiving experiences.


2014 ◽  
Vol 37 (12) ◽  
pp. 1110-1136 ◽  
Author(s):  
Daniel Kipkirong Tarus ◽  
Federico Aime

Purpose – The purpose of this study is to examine the effect of boards’ demographic diversity on firms’ strategic change and the interaction effect of firm performance. Design/methodology/approach – This paper used secondary data derived from publicly listed firms in Kenya during 2002-2010 and analyzed the data using fixed effects regression model to test the effect of board demographic and strategic change, while moderated regression analysis was used to test the moderating effect of firm performance. Findings – The results partially supported board demographic diversity–strategic change hypothesis. In particular, results indicate that age diversity produces less strategic change, while functional diversity is associated with greater levels of strategic change. The moderated regression results do not support our general logic that high firm performance enhances board demographic diversity–strategic change relationship. In effect, the results reveal that at high level of firm performance, board demographic diversity produces less strategic change. Originality/value – Despite few studies that have examined board demographic diversity and firm performance, this paper introduces strategic change as an outcome variable. This paper also explores the moderating role of firm performance in board demographic diversity–strategic change relationship, and finally, the study uses Kenyan dataset which in itself is unique because most governance and strategy research uses data from developed countries.


2021 ◽  
Vol 10 (2) ◽  
pp. 128-145
Author(s):  
Woosik Yu

This paper analyzes the effect of the so-called ‘brain drain’ on economic growth through the channel of growth in total factor productivity. We analyze panel data that measure the severity of brain drain, which are from IMD and the U.S. National Science Foundation. Our analysis shows that middle-income countries have more brain drain compared to the group of high-income countries. Also, emerging economies that grow fast tend to experience more brain drain. Our results from fixed effects regression models show that that brain drain has a significant and positive impact on economic growth, and the main channel is productivity growth. This can be considered as evidence of the positive effects of ‘brain circulation’, which is one of the brain drain phenomena that settlement of the talents in advanced countries can eventually help improve the productivity of home country by the sharing of advanced technologies and skills around them with colleagues in motherland. Therefore, a strategy of utilizing overseas resident talents should also be considered, alongside the brain-attraction policy.


Sign in / Sign up

Export Citation Format

Share Document