scholarly journals Adverse Perinatal Outcomes and Risk Factors for Preeclampsia in Women With Chronic Hypertension

Hypertension ◽  
2008 ◽  
Vol 51 (4) ◽  
pp. 1002-1009 ◽  
Author(s):  
Lucy C. Chappell ◽  
Stephen Enye ◽  
Paul Seed ◽  
Annette L. Briley ◽  
Lucilla Poston ◽  
...  
Keyword(s):  
Risk Factors ◽  
Perinatal Outcomes ◽  
Chronic Hypertension ◽  
Adverse Perinatal Outcomes

The effect of maternal position on fetal middle cerebral artery Doppler indices and its association with adverse perinatal outcomes: a pilot study

2020 ◽  
Vol 48 (4) ◽  
pp. 317-321
Author(s):  
Rodney McLaren ◽  
Bharati Kalgi ◽  
Chima Ndubizu ◽  
Peter Homel ◽  
Shoshana Haberman ◽  
...  
Keyword(s):  
High Risk ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Repeated Measures ◽  
Adverse Outcome ◽  
Perinatal Outcomes ◽  
Low Risk ◽  
Doppler Velocity ◽  
Chronic Hypertension ◽  
Adverse Perinatal Outcomes

AbstractObjectiveThe aim of this study was to compare position-related changes in fetal middle cerebral artery (MCA) Doppler pulsatility indices (PI).MethodsA prospective study of 41 women with conditions associated with placental-pathology (chronic hypertension, pregestational diabetes, and abnormal analytes) and 34 women without those conditions was carried out. Fetal MCA Doppler velocity flow waveforms were obtained in maternal supine and left lateral decubitus positions. MCA PI Δ was calculated by subtracting the PI in the supine position from the PI in the left lateral position. Secondary outcomes included a composite of adverse perinatal outcomes (fetal growth restriction, oligohydramnios, and preeclampsia). χ2 and Student t-tests and repeated-measures analysis of variance were used.ResultsMCA PI Δ was significantly less for high-risk pregnant women ([P = 0.03]: high risk, left lateral PI, 1.90 ± 0.45 vs. supine PI, 1.88 ± 0.46 [Δ = 0.02]; low risk, left lateral PI, 1.90 ± 0.525 vs. supine PI, 1.68 ± 0.40 [Δ = 0.22]). MCA PI Δ was not significantly different between women who had a composite adverse outcome and women who did not have a composite adverse outcome (P = 0.843).ConclusionOur preliminary study highlights differences in position-related changes in fetal MCA PI between high-risk and low-risk pregnancies. These differences could reflect an attenuated ability of women with certain risk factors to respond to physiologic stress.

scholarly journals 856A gestational age specific prognostic model for adverse perinatal events in obese women

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Jeffrey Bone ◽  
Sarka Lisonkova
Keyword(s):  
Risk Factors ◽  
British Columbia ◽  
Gestational Age ◽  
Proportional Hazards Model ◽  
Perinatal Outcomes ◽  
Cox Proportional Hazards Model ◽  
Prognostic Models ◽  
Chronic Hypertension ◽  
Obese Women ◽  
Increased Risk

Abstract Background Obesity is one of the most preventable pre-pregnancy risk factors for adverse perinatal events. Despite this, there are few body-mass-index (BMI) specific prognostic models for timing of delivery associated with the lowest number of adverse perinatal events. Our aim was to build a predictive model to quantify gestational age-specific rates of adverse birth outcomes in obese women with and without additional risk factors. Methods All singleton births at ≥ 34 weeks’ gestation in British Columbia, Canada, 2008-2017 (n = 283,697) were included and data were obtained from the British Columbia Perinatal Database Registry. A multivariable Cox proportional hazards model including demographic and obstetric risk factors was used to estimate gestational age specific risk of composite perinatal mortality and severe morbidity. Results Among all women, 13.1% were obese (pre-pregnancy BMI ≥30m/kg2), 60.1% had normal BMI (18.5-24.9 m/kg2). In high-risk obese women (nulliparous with chronic hypertension, and diabetes), adjusted outcome rates (per 1000 ongoing pregnancies) were 7.5 at 34-36 weeks, 20.4 at 37-39 weeks, and 83.5 at ≥ 40 weeks’ gestation. In all obese women, the rates were 1.93, 6.27, and 18.5 per 1000 ongoing pregnancies, respectively. In contrast, on average these rates were 1.14, 4.03 and 11.6 per 1000 ongoing pregnancies, respectively, among women with normal BMI. Conclusions Obese women are at increased risk of poor perinatal outcomes at all gestational ages. These risks are compounded by other conditions known to effect perinatal outcomes. Key messages Obese women require specific guidelines for timing of optimal delivery.

scholarly journals Exploring  the influence of advanced maternal age on adverse perinatal outcome in Southern Anhui province, China

2019 ◽  
Author(s):  
Dandan Ge ◽  
Mingshu Si ◽  
Yong Xia
Keyword(s):  
Risk Factors ◽  
Perinatal Outcome ◽  
Maternal Age ◽  
Multiple Logistic Regression Analysis ◽  
Multiple Pregnancy ◽  
Perinatal Outcomes ◽  
Advanced Maternal Age ◽  
Multiple Logistic Regression ◽  
Adverse Perinatal Outcome ◽  
Adverse Perinatal Outcomes

Abstract Background : Elderly parturient women may face many pregnancy risks, which have serious consequences for perinatal and maternal. The objective of this study is to explore the association between advanced maternal age and adverse perinatal outcomes. Methods : In this study, we used retrospective study to randomly selected 977 puerpera ( aged 35 years and older) as the research group and 977 puerpera (aged 20 to 34 years older) as the control group from Yijishan Hospital for the years 2017-2018. Univariate analysis was used to test the association between gestational age and adverse perinatal outcomes. Multiple logistic regression analysis was performed to examine the factors associated with adverse perinatal outcome. A nomogram was conducted to explore the risk probability between risk factors and adverse perinatal outcome. Results : the AMA group (23.2%)exhibited a higher incidence of adverse perinatal outcome than the Non-AMA group(17.8%). Multiple logistic regression analysis showed among those who experienced multiple pregnancy, premature, hypertension, diabetes were more likely to induce adverse perinatal outcome. In this study, the risk of adverse perinatal outcome occurred in women aged 35 to 45 years with multiple pregnancy and preterm birth all was 42%-48%. The risk of adverse perinatal outcome in women aged 35 to 45 years with other variables respectively were 18%-19% (diabetes), 16%-18% (hypertension).The risk of adverse perinatal outcomes among women with AMA combined with these variables were higher than the counterpart. Conclusions : AMA is the risk factor for adverse perinatal outcome among pregnancy women and the probability that these risk factors combined with age produced poor perinatal outcome were also found. Active intervention measures focusing on the complications and treatment in AMA should be taken to ensure the health of mother and baby.

scholarly journals Role of umbilical artery Doppler velocimetry in predicting the adverse perinatal outcomes in hypertensive disorder of pregnancy

2017 ◽  
Vol 6 (10) ◽  
pp. 4382
Author(s):  
Jyoti Yadav ◽  
Mala Shukla ◽  
P. K. Jain ◽  
Devender Kumar
Keyword(s):  
Predictive Value ◽  
Perinatal Outcome ◽  
Umbilical Artery ◽  
Perinatal Outcomes ◽  
Chronic Hypertension ◽  
Hypertensive Disorder ◽  
Umbilical Artery Doppler ◽  
Hypertensive Disorder Of Pregnancy ◽  
Adverse Perinatal Outcomes ◽  
Group B

Background: Early detection of fetoplacental compromise with Umbilical Artery Doppler indices and to know the predictive value of each indices in predicting perinatal outcome and interventional strategies in these patients.Methods: The present prospective study was conducted on 200 women with hypertensive disorder of pregnancy. Umbilical artery doppler evaluation done in all the patients at (28-32) weeks, (33-36) weeks and (37-40) weeks of gestation and more frequently in those patients having deranged Doppler. Patients divided into two groups women with abnormal Umbilical artery indices (group B) and normal indices (group A). Perinatal outcome of both the groups were compared, analyzed statistically using Chi-square test. Multiple pregnancy, chronic hypertension, fetal congenital anomalies, systemic disease and those lost to follow up till delivery were excluded from study.Results: A total of 200 pregnant women with hypertensive disorder, 64% were primgravida. Abnormal umbilical artery indices seen in 36%. Adverse outcome was seen in 88.88% patients of group B. Statistically significantly higher rate of caeserian section, induction of labour, Preterm delivery, fetal growth restriction, NICU admission, NICU stay >48hrs were seen in group B. In all indices Umbilical artery PI had highest Sensitivity (84.21%), positive predictive value (88.88%) and accuracy (90%).Conclusions: Umbilical artery PI is the most reliable to predict adverse perinatal outcomes and help in appropriate timing of intervention to improve perinatal outcome.

Adverse perinatal outcomes in patient with chronic hypertension by insurance type

2022 ◽  
Vol 226 (1) ◽  
pp. S507-S508
Author(s):  
Uma Doshi ◽  
Claire H. Packer ◽  
Alyssa R. Hersh ◽  
Amy M. Valent
Keyword(s):  
Perinatal Outcomes ◽  
Chronic Hypertension ◽  
Insurance Type ◽  
Adverse Perinatal Outcomes

scholarly journals Maternal and Placental Risk Factors associated with Intrauterine Growth Restriction and the Perinatal Outcomes

2015 ◽  
Vol 7 (3) ◽  
pp. 176-181 ◽  
Author(s):  
Valsa CA Thekkedathu
Keyword(s):  
Risk Factors ◽  
Statistical Analysis ◽  
Intrauterine Growth Restriction ◽  
Perinatal Outcomes ◽  
Growth Restriction ◽  
Chronic Hypertension ◽  
Maternal Risk ◽  
Intrauterine Growth ◽  
Factors Associated ◽  
The Impact

ABSTRACT Objectives Identifying the factors responsible for the intrauterine growth restriction (IUGR) is very important, so that early interventions could be suggested to improve the perinatal outcome. The major objectives of this study are to analyze the impact of risk factors, specifically the maternal and placental risk factors, on IUGR and the perinatal outcomes. Materials and methods A prospective study was done on 60 women with IUGR pregnancies from January 2013 to January 2014, at Pushpagiri Medical College Hospital, Thiruvalla. Inclusion criteria were: singleton pregnancies, above the gestational age of 28 weeks, clinically diagnosed IUGR and confirmed subsequently on ultrasound. The statistical analysis was performed utilizing Statistical Package of the Social Sciences (SPSS) software and the significance level of p-value < 0.05 was accepted as statistically significant. Results Statistical analysis shows that maternal risk factors like chronic hypertension, pre-eclampsia, low socioeconomic status of mother, overt diabetes, anemia, gestational diabetes mellitus, low prepregnancy body mass index and hypothyroidism were significantly associated with IUGR. In this study, placental factors like chorangiomatosis, increased syncytial knotting, villous infarction, increased perivillous fibrinoid deposition, accelerated villous maturation, retroplacental hemorrhage and acute chorioamnionitis were significantly associated with IUGR. Conclusion Alertness toward antenatal risk factors for poor pregnancy outcome is important for the optimal management of IUGR pregnancies. Despite antenatal recognition of IUGR and associated risk factors, not all perinatal deaths can be prevented. How to cite this article Thekkedathu VCA. Maternal and Placental Risk Factors associated with Intrauterine Growth Restriction and the Perinatal Outcomes. J South Asian Feder Obst Gynae 2015;7(3):176-181.

scholarly journals Risk factors for adverse perinatal outcomes depend on smoking status, a study from a developing country

2021 ◽  
Author(s):  
Shereen Hamadneh ◽  
Jehan Hamadneh
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Maternal Education ◽  
Smoking Status ◽  
Perinatal Outcomes ◽  
Monthly Income ◽  
Smoking During Pregnancy ◽  
Adverse Perinatal Outcomes ◽  
Nicu Admission ◽  
Control Study

Background: This study aimed to investigate the risk factors for smoking and negative perinatal outcomes among Jordanian women about smoking status. Methods: A case-control study was conducted among singleton full-term pregnant women who gave birth at the main hospital in Jordan in June 2020. They were divided into three groups according to their smoking status (active, passive and non-smokers) and were interviewed using a semi-structured questionnaire, including demographic information, current pregnancy history, perinatal and neonatal outcomes. The study investigated the effect of smoking status on both independent and dependent variables. Results: Our study revealed that low-level maternal education (OR=25.38), unemployed maternal status (OR=2.67), the absence of following up during pregnancy (OR=5.8), smoking husband were risk factors for smoke exposure among pregnant women. The risk for cesarean section was increased in nulliparous smoking women (OR=9.0), those with low family monthly income (OR=7.8), and those who did not get any information about the hazard effect of smoking (OR=4.38), as well as in unemployed passive smoking women (OR=6.25). Parity of more than one has raised the risk of NICU admission inactive smoking women (OR=10.38). This risk was also increased in active and passive women with a lower level of education (OR=186.33 and OR=17.5), respectively, as well as inactive smoking women with low family monthly income (OR=4.11). Conclusions: Appropriate preventive strategies should focus on modifiable risk factors for smoking during pregnancy.

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