scholarly journals Reference Standards for Cardiorespiratory Fitness by Cardiovascular Disease Category and Testing Modality: Data From FRIEND

2021 ◽  
Author(s):  
James E. Peterman ◽  
Ross Arena ◽  
Jonathan Myers ◽  
Susan Marzolini ◽  
Philip A. Ades ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Cardiorespiratory Fitness ◽  
Clinical Care ◽  
Cardiopulmonary Exercise Testing ◽  
Age Groups ◽  
Reference Standards ◽  
National Database ◽  
Disease Category ◽  
Men And Women ◽  
The Mean

Background The importance of cardiorespiratory fitness for stratifying risk and guiding clinical decisions in patients with cardiovascular disease is well‐established. To optimize the clinical value of cardiorespiratory fitness, normative reference standards are essential. The purpose of this report is to extend previous cardiorespiratory fitness normative standards by providing updated cardiorespiratory fitness reference standards according to cardiovascular disease category and testing modality. Methods and Results The analysis included 15 045 tests (8079 treadmill, 6966 cycle) from FRIEND (Fitness Registry and the Importance of Exercise National Database). Using data from tests conducted January 1, 1974, through March 1, 2021, percentiles of directly measured peak oxygen consumption (VO 2peak ) were determined for each decade from 30 through 89 years of age for men and women with a diagnosis of coronary artery bypass surgery, myocardial infarction, percutaneous coronary intervention, or heart failure. There were significant differences between sex and age groups for VO 2peak ( P <0.001). The mean VO 2peak was 23% higher for men compared with women and VO 2peak decreased by a mean of 7% per decade for both sexes. Among each decade, the mean VO 2peak from treadmill tests was 21% higher than the VO 2peak from cycle tests. Differences in VO 2peak were observed among the age groups in both sexes according to cardiovascular disease category. Conclusions This report provides normative reference standards by cardiovascular disease category for both men and women performing cardiopulmonary exercise testing on a treadmill or cycle ergometer. These updated and enhanced reference standards can assist with patient risk stratification and guide clinical care.

A history of smoking does not reduce long-term benefits of cardiac rehabilitation on cardiorespiratory fitness in men and women with cardiovascular disease

2020 ◽  
Author(s):  
Kenneth Shinkichi Noguchi ◽  
Michael Pryzbek ◽  
Kevin Moncion ◽  
Angelica McQuarrie ◽  
Maureen J. MacDonald ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Cardiac Rehabilitation ◽  
Cardiorespiratory Fitness ◽  
Smoking Behaviour ◽  
Smoking History ◽  
Cardiac Events ◽  
Men And Women ◽  
All Cause Mortality ◽  
History Of

Smoking is an important risk factor for cardiovascular disease and all-cause mortality. Cardiac rehabilitation (CR) is effective for reducing the risk of recurrent cardiac events through improving cardiorespiratory fitness (CRF). Little is known about the influence of smoking on CRF throughout long-term CR. The purpose of this analysis was to compare CRF trajectories among individuals with positive and negative smoking history enrolled in long-term CR. Participants had a positive smoking history if they currently smoke or formerly smoked (Smoke+, n=55, mean age=64.9 ± 9.0 years) and had a negative history if they never smoked (Smoke–, n=34, mean age=61.4 ± 9.0 years). CRF (VO2peak) was measured at baseline and annually thereafter for 6 years. The Smoke+ group had lower CRF compared to the Smoke– group over enrollment (β=-3.29 (SE=1.40), 95% CI -6.04, -0.54, p=0.02), but there was no interaction of smoking history and enrollment (β=0.35 (SE=0.21), 95% CI -0.06, 0.77, p=0.10). Moreover, trajectories were not influenced by pack-years (β=0.01 (SE=0.01), 95% CI -0.01, 0.04, p=0.23) or time smoke-free (β=-0.002 (SE=0.01), 95% CI -0.02, 0.02, p=0.80). Although the trajectories of CRF do not appear to be affected by smoking behaviour, individuals without a history of smoking maintained higher CRF throughout enrollment. Novelty bullets: • The benefits of long-term exercise-based cardiac rehabilitation on cardiorespiratory fitness are similar between those who have smoked and those who have never smoked. • Neither the number of pack-years nor the length of time spent smoke-free influence cardiorespiratory fitness trajectories following long-term cardiac rehabilitation.

scholarly journals Obesity trends in populations of the Russian Federation and the United States of America. Thirty-year long dynamics

2018 ◽  
Vol 17 (4) ◽  
pp. 67-73 ◽  
Author(s):  
V. G. Vilkov ◽  
S. A. Shalnova ◽  
A. D. Deev ◽  
Yu. A. Balanova ◽  
S. E. Efstifeeva ◽  
...  
Keyword(s):  
Russian Federation ◽  
Age Groups ◽  
The United States ◽  
Men And Women ◽  
The Us ◽  
Obesity Trends ◽  
Prevalence Of Obesity ◽  
The Mean ◽  
And Gender ◽  
Gender Categories

Aim. To evaluate the dynamics of obesity and mean body mass index (BMI) in Russia and USA in various age and gender categories during 1975-2014.Material and methods. By a repeat analysis of one-moment studies of Russian and US population in 1975-1982 and 2007-2014, the values of obesity and BMI were assessed in men and women age 25-64 y. o. Into analysis, the data was included from Russian part of the Lipid Clinics study and multicenter ESSE-RF study (Epidemiology of cardiovascular diseases and risk factors in various regions of Russian Federation). American data acquired from the studies NHANES (National Health And Nutrition Examination Survey), open access. Total number of observations 48974.Results. In the 80s of XX century in all age groups of women the mean BMI levels were lower in USA comparing to Russia, in men there were no significant differences. For the following 30 years in Russia the situation improved for men and women <45 y. o. — differences with USA changed modality, and currently BMI in Russia is lower than in USA.Conclusion. Russia was below the US 30 years ago by the mean BMI in females of all ages, with no differences for males. For the following 30 years in the US there was significant increase of BMI in all age strata of men and women, and in Russia dynamics was the same, but lesser. Comparison of the prevalence of obesity in men 30 years ago showed some predominance of obesity in American males, especially young, but not statistically significant. Russian women had higher prevalence of obesity regardless of age. Currently, obesity in young age is more prevalent in men and women of USA, and >45 years old — in Russia.

scholarly journals Daily sitting time and physical performance in oldest adults

2018 ◽  
Vol 32 (1) ◽  
pp. 17-24
Author(s):  
Lucélia Justino Borges ◽  
Renata Da Conceição ◽  
Vandrize Meneghini ◽  
Tiago Rosa de Souza ◽  
Aline Rodrigues Barbosa
Keyword(s):  
Physical Performance ◽  
Age Groups ◽  
Community Dwelling ◽  
Sitting Time ◽  
Limiting Factor ◽  
Cross Sectional ◽  
Men And Women ◽  
Stand Test ◽  
Sit To Stand ◽  
The Mean

The aim of this study was to verify the physical performance (PP) and daily sitting time in the oldest population in a rural community dwelling in southern Brazil. In addition, to analyze the association between physical performance tests (PPT) and daily sitting time (ST). This was a cross-sectional, population-based household study. All residents aged 80 years and older were examined in 2010. PPT included standing balance (four measures of static balance), five times “sit-to-stand” test and “pick up a pen” test (assessed by time). Daily ST was estimated by questionnaire. Women of the younger age groups displayed better results in the PPT compared to older women. The men had good results in the tests, independent from their age group (except for 95-100 years of age). For women, the mean time in the “sit to stand” test decreased with the advancing age, whereas for men, we observed the opposite. Men and women displayed similar means in the “pick up a pen” test. The mean daily ST increased with the advancement of age. After adjustment for sex, age, and number of morbidities, the daily ST was ~52 minutes lower for those with better balance (β -52.6; p = 0.001). For those with better performance in the “sit to stand” test, the time was ~35 minutes lower (β -35.8; p = 0.001). Men and women differ in the rate of decline in PPT. The results suggest that longer sitting time is a limiting factor of good performance in tests for the oldest of the population.

scholarly journals MON-180 Risk for Hypercoagulability Among Patients with Cushing Syndrome. From the National Inpatient Sample

2020 ◽  
Vol 4 (Supplement_1) ◽  
Author(s):  
Fatima Ahmed ◽  
Ashraf Abugroun ◽  
Manar Elhassan ◽  
Berhane Seyoum ◽  
Wael Taha
Keyword(s):  
Cushing Syndrome ◽  
Metastatic Cancer ◽  
Multivariable Analysis ◽  
Age Groups ◽  
Young Patients ◽  
Hypercoagulable State ◽  
National Database ◽  
Control Group ◽  
National Inpatient Sample ◽  
The Mean

Abstract Background: Patients with Cushing syndrome are at higher risk for hypercoagulability due to elevated levels of pro-coagulants and impaired fibrinolysis. Objective: We aimed to examine the association of Cushing syndrome and hypercoagulability using a large national database. Methods: The National Inpatient Sample (NIS) was queried for all patients diagnosed with Cushing syndrome during the year 2011-2015. Patients with Cushing syndrome were identified using the international classification of diseases (ICD-9) code “2550”. The control group was randomly selected from the same database in a 4:1 ratio matched by age and gender. Hypercoagulable state was defined by presence of either ICD-9 codes “28981 or 28982” for primary and secondary hypercoagulable state as well as personal history of venous thrombosis or pulmonary embolism identifed with ICD-9 codes “V1251 and V1255” respectively. Patients who were diagnosed with autoimmune diseases, solid tumors, metastatic cancer, as well as those who were bed-bound were excluded. Multivariable logistic regression with adjustment for patient’s demographics, socioeconomic factors, comorbidities and hospital factors was used to obtain Cushing syndrome related risk for hypercoagulability. Subgroup analysis was performed based on gender, race and age groups; young adults (aged 18-35 years), middle-aged (&gt; 35-&lt;55 years) and older adults (aged &gt; 55 years). Results: A total of 43,157 patients diagnosed with Cushing syndrome were identified. The mean age was 53.9 years (standard error of the mean 0.1). Majority of patients were females (75.2%) and of Caucasian race (74.6%). The prevalence of hypercoagulability was markedly higher among patients with Cushing syndrome 10 % vs 4%, p &lt;0.001. On multivariable analysis, presence of Cushing syndrome correlated with significanlty higher risk for hypercoagulability with adjusted odd ratio (a OR) 2.20 [95%CI: 1.98-2.44] p &lt;0.001. The risk for hypercoagulability was highest among young patients (age ≤ 35) with a OR 6.02 [95%CI: 4.06-8.94] p&lt;0.001 and among Hispanics with a OR 3.66 [95%CI: 2.38-5.64] p&lt;0.001. No significant gender difference on risk for hypercoagulability. Conclusion: Patients with Cushing syndrome are at higher risk for hypercoagulability. This risk is markedly higher among young patients and among Hispanics. Particular attention for early detection and prevention of venous thromboembolism in patients with Cushing Syndrome is advisable.

scholarly journals Prevalence and incidence of type 2 diabetes in Iceland 2005-2018

2021 ◽  
Vol 107 (05) ◽  
pp. 227-233
Author(s):  
Bolli Þórsson ◽  
◽  
Elías Freyr Guðmundsson ◽  
Gunnar Sigurðsson ◽  
Thor Aspelund ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Age Groups ◽  
Similar Rate ◽  
Population Based ◽  
National Database ◽  
Published Data ◽  
Prescription Database ◽  
Men And Women ◽  
The Usa

INTRODUCTION: The number of people with type 2 diabetes has increased in Iceland in the last few decades. We utilized the national database on prescribed medication from the Directorate of Health to estimate the prevalence and incidence of type 2 diabetes in Iceland and made prediction on the prevalence of type 2 diabetes in Iceland in 10 and 20 years. MATERIAL AND METHODS: Prevalence and incidence of type 2 diabetes for the period 2005-2018 was estimated based on prescriptions of diabetes medication in the national prescription database containing all prescriptions in Iceland during the period. The result was compared to the result from the REFINE-Reykjavik study (prospective, population-based cohort study) from 2004 to 2011 and published data from the USA from 1980 to 2016. RESULTS: The prevalence of type 2 diabetes more than doubled in near all age groups in both men and women in the period 2005-2018. The incidence increased by 2.8% annually (in 18-79 years old). The number of people in Iceland with type 2 diabetes was 10600 in 2018 and had increased from 4200 in the year 2005. Comparison with the results of the REFINE-Reykjavik study showed an underestimation (29% in men and women) of the prevalence of type 2 diabetes. If the increase in type 2 diabetes continues at a similar rate as in the years 2005-2018 the number of people with diabetes in Iceland could be near 24000 in the year 2040. CONCLUSION: Linear increase was seen in incidence and prevalence of people with type 2 diabetes in the years 2005-2018. Similar evolution was seen in USA from 1984. In order to counteract the increase of type 2 diabetes following the same path as has been seen in the USA, targeted measures are needed.

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