Abstract T P126: Diabetes Mellitus and K-Modified Barthel Index at 6 Months after Stroke: A Prospective Multicenter Study

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Shin Yi Jang ◽  
Yun-Hee Kim ◽  
Min Kyun Sohn ◽  
Jongmin Lee ◽  
Deog Young Kim ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Barthel Index ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Age Groups ◽  
The Elderly ◽  
Elderly Group ◽  
Middle Aged ◽  
Aged Group ◽  
The Mean

Introduction: Few studies investigated the diabetes mellitus (DM) as a predictable factor of 6 months K-Modified Barthel Index (KMBI) outcome after stroke. Aims: The aim of this study is to investigate whether DM predicts the outcome of KMBI at 6-month after stroke with adjustment for cardiovascular disease risk factors, socioeconomic position and health behavior factors. Methods: This is an interim report of the Korean Stroke Cohort for Functioning and Rehabilitation (KosCo). The sample included 1,199 stroke patients aged 45-92 years. FIM score was assessed at 6 months after onset. We divided subjects into two age groups: the middle aged (45-64 year-old) and the elderly (over 65 year-old). Subjects who met one of the following requirements were defined as having DM: taking an oral hyperglycemic agent, using insulin, clinical diagnosis of diabetes, or a fasting glucose level >125 mg/dL. Results: The mean age of the middle aged group was 55.8(±5.44) year-old and the elderly group was 74.3(±6.14)(p<0.001). The distribution of DM was 20.8% and 28.9%, respectively (p<0.001). The mean 6-Month KMBI was 91.7 (±20.7) and 78.4 (±33.1), respectively (p<0.001). The 6-Month KMBI significantly decreased in DM group compared to the non DM group after adjustment for confounding factors. In the middle aged group, the 6-Month KMBI decreased in DM group (p<0.01), but in the elderly group. Conclusions: This hospital-based cohort study showed that DM may predict poor 6-Month KMBI outcome, especially, for the middle aged group (Supported by Korea Centers for Disease Control and Prevention (2013E3301701)).

scholarly journals Common and Uncommon Imaging Appearances of COVID-19 Pneumonia in Young and Middle-Aged Group and Elderly Group

2021 ◽  
Author(s):  
Alireza Mahmoudabadi ◽  
Hamed Masoumi ◽  
Mohammad Keshtkar ◽  
Arash Azhideh ◽  
Hamidreza Haghighatkhah
Keyword(s):  
Pleural Effusion ◽  
Ground Glass Opacity ◽  
The Elderly ◽  
Ct Images ◽  
Elderly Group ◽  
Wall Thickening ◽  
Lung Region ◽  
Middle Aged ◽  
Aged Group ◽  
Lower Lung

Purpose: In this study, we retrospectively evaluated chest Computed Tomography (CT) imaging manifestations of the patients with Coronavirus Disease 2019 (COVID-19) to simplify prompt early diagnosis of disease and speed up needed actions for infected patients. Materials and Methods: Totally, 75 patients who laboratory confirmed COVID-19 pneumonia were enrolled in this study. CT images, demographic and some clinical data of all patients were collected and analyzed retrospectively. Furthermore, for comparison, the patients were divided into two groups as follows: the young and middle-aged group (< 60 years old) and the elderly group (≥ 60 years old). Results: Based on the evaluation of CT images, 33 patients (44%) showed Ground-Glass Opacity (GGO), 15 patients (20%) showed consolidation, 24 patients (32%) showed mixed GGO and consolidation, 2 patients (2.6%) had bronchial wall thickening, 10 patients (13.3%) had a crazy paving sign, 35 patients (46.6%) had air bronchogram and, 7 patients (9.3%) had cavitation and 2 patients (2.6%) had a tree in the bud. CT images of 3 patients (4%) were normal. In terms of out of lung changes, lymphadenopathy was observed in one patient (1.3%), pleural effusion in 12 patients (16%), and pericardial effusion in 2 patients (2.6%). Lesions were found predominantly in the peripheral (57.3%) and the lower lung region (60%). Conclusion: CT images of the COVID-19 patients showed various aspects, mainly GGO, consolidation, mixed GGO and consolidation, and air bronchogram. Lesion distribution was predominantly in lower lung region, bilateral and peripheral. Pleural effusion and multiple lobe involvement were significantly higher in the elderly group than that of the young and middle-aged group.

scholarly journals Correlation Between Blood Pressure Variability and Plasma Renin–Angiotensin–Aldosterone Levels in Patients With Essential Hypertension at Different Ages

2020 ◽  
Vol 33 (6) ◽  
pp. 581-581
Author(s):  
Cai-ni Fan ◽  
Hai-ying Zhao ◽  
Dan-dan Tian ◽  
Hao Wang
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Blood Pressure Variability ◽  
Plasma Renin ◽  
The Elderly ◽  
Young Group ◽  
Moderate Essential Hypertension ◽  
Elderly Group ◽  
Middle Aged ◽  
Aged Group

Abstract Background To study the correlation between blood pressure variability (BPV) and plasma renin activity (PRA), angiotensin II (AngII), aldosterone levels in patients with essential hypertension. Methods A total of 300 patients with mild to moderate essential hypertension were analyzed retrospectively. The subjects were divided into 3 age groups: 100 patients aged 18–44 years (young group), 110 patients aged 45–64 years (middle-aged group), and 90 patients aged over 65 years (elderly group). PRA, AngII, and aldosterone levels were assessed. Blood pressure (BP) was measured by 24-hour ambulatory BP monitoring. The relationships between BP variability and the PRA, AngII, aldosterone levels were compared among the 3 groups. Results Supine and upright PRA and aldosterone levels were significantly higher in the young group than those in the middle-aged and elderly groups. The coefficient of variation (CV) of 24-hour systolic (24hSBPCV), diastolic BP (24hDBPCV), CV of daytime systolic (dSBPCV), diastolic (dDBPCV), and nighttime systolic BP (nSBPCV) in the elderly group was higher than those in the young group and the middle-aged group (all P &lt; 0.05). Spearman correlation analysis showed that in the young and middle-aged groups, BPV was significantly correlated with the levels of PRA, AngII, and aldosterone (all P &lt; 0.05). In the elderly group however, only 24hDBPCV, nDBPCV, and nSBPCV were correlated with AngII and aldosterone levels (all P &lt; 0.05). Conclusions BPV is correlated with plasma renin–angiotensin–aldosterone levels in young and middle-aged patients with mild to moderate essential hypertension.

scholarly journals Intra-Articular Hyaluronic Acid as Treatment in Elderly and Middle-Aged Patients with Knee Osteoarthritis

2013 ◽  
Vol 7 (1) ◽  
pp. 38-41 ◽  
Author(s):  
Demet Uçar ◽  
Demirhan Dıraçoğlu ◽  
Türker Süleyman ◽  
Nalan Çapan
Keyword(s):  
Hyaluronic Acid ◽  
Knee Osteoarthritis ◽  
The Elderly ◽  
Elderly Group ◽  
Middle Aged ◽  
Old Patients ◽  
Aged Group ◽  
The Third ◽  
Age Related ◽  
One Year

Introduction: Osteoarthritis is the most common age-related degenerative joint disease. It affects all the joints containing hyaline cartilage. Knee osteoarthritis is the most cumbersome in terms of prevalence and disability. The aim of this study to evaluate the efficacy of intra-articular hyaluronic acid in patients with knee osteoarthritis with regard to joint pain and function, as well as patient satisfaction, assessed at one month and at one year, and by age group. Methods: In this prospective randomised study, 172 patients who were diagnosed knee OA and who received three consecutive intra-articular injections of HA weekly were included. Patients 65 years of age or older were accepted as the “elderly group”, and those under 65 were accepted as the “middle-aged group”. Clinical evaluations of efficacy and safety were conducted at the beginning of the study, one month after the third injection, and one year after the third injection. Results: In the two groups, the intragroup analysis revealed significant improvements following injection when compared with preinjection values. According to the last followup controls (after 12 months) in the middle-aged group, VAS activity pain, VAS rest pain, WOMAC physical function, and WOMAC pain values were found to be statistically lower when compared with pre-injection values. In the elderly group, no statistically significant differences were found between pre-injection and after 12 months. Conclusion: We can conclude that intra-articular joint HA injections are effective in both young and old patients with OA with regard to pain and functional status over a short-term period. Further, HA injections in patients younger than 65 years can be planned for a one-year period.

Abstract W P128: The Effect of Obesity on K-Modified Barthel Index at 6 Months after Stroke: A Prospective Multicenter Study

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Shin Yi Jang ◽  
Yun-Hee Kim ◽  
Min Kyun Sohn ◽  
Jongmin Lee ◽  
Deog Young Kim ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Functional Outcome ◽  
Barthel Index ◽  
Disease Risk ◽  
Cardiovascular Disease Risk ◽  
Stroke Onset ◽  
Obese Group ◽  
Stroke Patients ◽  
Control And Prevention ◽  
The Mean

Introduction: Previously, association between body mass index (BMI) and K-Modified Barthel Index (KMBI) score was reported. However, few studies investigated the value of obesity as a predictive factor of 6 months functional outcome after stroke. Aims: The aim of this study is to examine whether BMI predicts the 6-month KMBI after stroke onset with adjustment for cardiovascular disease risk factors socioeconomic position and health behavior factors in stroke patients. Methods: This is an interim report of the Korean Stroke Cohort for Functioning and Rehabilitation (KosCo). The sample included 1,299 stroke patients, both ischemic and hemorrhagic, aged 18-92 years. FIM score was assessed at 6 months after stroke onset. Subjects were classified into three groups based on their baseline BMI categories at admission: normal (18.5 ≤ BMI < 23), overweight (23 ≤ BMI < 25), or obese (BMI ≥ 25) groups. Results: The mean age was 64.1 (±12.8) years. The distribution of overweight and obese groups was 28.5 % and 36.3 %, respectively. The mean 6-month KMBI was 85.6 (±27.6) and 88.0 (±26.0), respectively. The 6-month KMBI significantly increased in obese group compared to the normal BMI group after adjustment for confounding factors. In the ischemic stroke, the 6-month KMBI was increased in the obese group (p<0.05), but not in the hemorrhagic stroke. Conclusions: This hospital-based cohort study showed that obesity measured by BMI may predict good 6 months functional outcome, especially, for the ischemic stroke patients (Supported by Korea Centers for Disease Control and Prevention (2013E3301701)).

scholarly journals Contact-Induced Vowel Variation: A Case Study of the Short High Vowels /i/ and /u/ in CVN Syllables in Lue and Khün

MANUSYA ◽  
2011 ◽  
Vol 14 (2) ◽  
pp. 53-87
Author(s):  
Phinnarat Akharawatthanakun
Keyword(s):  
Age Groups ◽  
Young Group ◽  
Elderly Group ◽  
Age Group ◽  
Middle Aged ◽  
Aged Group ◽  
Language Resource ◽  
Group 15 ◽  
High Vowels

This paper presents the variation in the two short high vowels /i/ and /u/ occurring in live syllables ending with final nasal consonants (CVN) in two Southwestern Tai (SWT) dialects: Lue and Khün, respectively spoken in the villages of Nong Bua and Nong Muang in Pa Kha Subdistrict, Tha Wang Pha District, in Nan Province. The data were collected from Lue and Khün language resource persons (LRPs) in three age groups, an elderly group (60 years old and above), a middle-aged group (35–50 years old), and a young group (15–25 years old), with five LRPs in each age group. The data analyzed for this paper come from a total of 30 LRPs (5 LRPs × 3 age groups × 2 SWT dialects).

scholarly journals Consumption of melatonin supplement improves cardiovascular disease risk factors and new anthropometric indices (as predictors of obesity) in type 2 diabetes mellitus patients: A double–blind, randomized, placebo-controlled trial

2020 ◽  
Author(s):  
Hadi Bazyar ◽  
Ahmad Zare Javid ◽  
Hossein Bavi Behbahani ◽  
Fardin Moradi ◽  
Bahman Moradi Poode ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Disease Risk ◽  
Controlled Trial ◽  
Cardiovascular Disease Risk ◽  
Intervention Group ◽  
Control Group ◽  
Anthropometric Indices ◽  
Double Blind ◽  
The Mean ◽  
Conicity Index

Abstract Background: Diabetes mellitus is a common chronic disease. Dyslipidemia and hypertension are two complications may develop in diabetic patients if hyperglycemia, insulin resistance, and weight gain are not controlled. The objective of this study was to investigate the effects of melatonin supplementation on some cardiovascular disease risk factors and new anthropometric indices in patients with type 2 diabetes mellitus (T2DM).Materials and Methods: In this double-blind, randomized, placebo-controlled trial, 50 T2DM patients were randomly allocated to intervention and control groups. The intervention and control groups received either 2 tablets melatonin or placebo (250 mg) once a day for 8 weeks. Mean arterial pressure (MAP), pulse pressure (PP), atherogenic index of plasma (AIP), body shape index (ABSI), abdominal volume index (AVI), body adiposity index (BAI), lipid accumulation product (LAP), conicity index, and waist to height ratio (WHR) were evaluated in all patients pre and post-intervention.Results: Melatonin supplementation for 8 weeks significantly decreased the mean levels of MAP, PP, BAI, AVI, conicity index, and WHR post intervention (p <0.05). Also, the mean changes of MAP, PP, BAI, AVI, and Conicity index were significantly lower in the intervention group compared with the control group (p <0.05). A significant increase (p <0.001) was observed in the mean levels of ABSI in the intervention group. The mean changes of ABSI was significantly greater in the intervention group compared with the control group (p <0.001).Conclusions: Consumption of melatonin supplement may be effective in controlling arterial pressure and new anthropometric indices (as predictors of obesity) in T2DM patients.Trial registration: This trial was registered in the Iranian Registry of Clinical Trials website at 2019/5/17. (IRCT20190303042905N1).

The Effects of Significant International Sports Events on Hungarian Suicide Rates

Crisis ◽  
2016 ◽  
Vol 37 (2) ◽  
pp. 148-154 ◽  
Author(s):  
Karoly Bozsonyi ◽  
Peter Osvath ◽  
Sandor Fekete ◽  
Lajos Bálint
Keyword(s):  
Significant Relationship ◽  
Olympic Games ◽  
Arima Model ◽  
Age Groups ◽  
The Elderly ◽  
Intervention Analysis ◽  
Middle Aged ◽  
Sports Events ◽  
Sport Events ◽  
The Olympic Games

Abstract. Background: Several studies found a significant relationship between important sport events and suicidal behavior. Aims: We set out to investigate whether there is a significant relationship between the raw suicide rate and the most important international sports events (Olympic Games, FIFA World Cup, UEFA European Championship) in such an achievement-oriented society as the Hungarian one, where these sport events receive great attention. Method: We examined suicide cases occurring over 15,706 days between January 1, 1970, and December 31, 2012 (43 years), separately for each gender. Because of the age-specific characteristics of suicide, the effects of these sport events were analyzed for the middle-aged (30–59 years old) and the elderly (over 60 years old) generations as well as for gender-specific population groups. The role of international sport events was examined with the help of time-series intervention analysis after cyclical and seasonal components were removed. Intervention analysis was based on the ARIMA model. Results: Our results showed that only the Olympic Games had a significant effect in the middle-aged population. Neither in the older male nor in any of the female age groups was a relationship between suicide and Olympic Games detected. Conclusion: The Olympic Games seem to decrease the rate of suicide among middle-aged men, slightly but significantly.

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