Ultraviolet-Fluorescence Bronchoscopy in Early Detection of Bronchogenic Carcinoma

1978 ◽  
Vol 87 (4) ◽  
pp. 528-532 ◽  
Author(s):  
Dietrich Hürzeler
Keyword(s):  
Early Detection ◽  
Optical System ◽  
Bronchogenic Carcinoma ◽  
Uv Light ◽  
Naked Eye ◽  
Ciliary Action ◽  
Malignant Changes ◽  
Normal Mucous Membrane ◽  
Superficial Tumor ◽  
Detailed Diagnosis

The still unsatisfactory prognosis of bronchogenic carcinoma prompted the search for possibilities of better early and detailed diagnosis. This led us to the idea of UV-fluorescence bronchoscopy. The patient inhales 5 ml of an aqueous 5% solution of fluorescein, together with a β2 stimulator, 10–15 minutes before the bronchoscopy, by means of a pressure inhaler. While the normal mucous membrane cleanses itself by virtue of ciliary action (secretions containing fluorescein are expectorated or drawn off during the bronchoscopy), carcinoma, carcinomatous lymphangiosis, superficial tumor infiltrations and nonciliated metaplasias are stained. These places fluoresce in UV light, even when they cannot be observed with the naked eye or with an optical system. In this way, they are made visible for directed biopsy. Malignant changes not discernible by means of the methods hitherto employed can thus be diagnosed and sites determined with greater accuracy for proposed resection.

scholarly journals Redesigning Skin Cancer Early Detection and Care Using a New Mobile Health Application: Protocol of the SKIN Research Project, a Randomised Controlled Trial

Dermatology ◽  
2018 ◽  
Vol 235 (1) ◽  
pp. 11-18 ◽  
Author(s):  
Monika Janda ◽  
Caitlin Horsham ◽  
Uyen Koh ◽  
Nicole Gillespie ◽  
Lois J. Loescher ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Early Detection ◽  
Controlled Trial ◽  
Skin Lesions ◽  
Mobile Technologies ◽  
Whole Body ◽  
Naked Eye ◽  
Cancer Early Detection ◽  
Reported Data ◽  
Randomised Controlled

Patients often detect melanoma themselves; therefore, regular skin self-examinations (SSEs) play an important role in the early detection and prompt treatment of melanoma. Mobile teledermoscopy is a technology that may facilitate consumer SSEs and rapid communication with a dermatologist. This paper describes the planned randomised controlled trial of an intervention to determine whether mobile technologies can help improve the precision of SSE in consumers. A randomised controlled trial will be conducted to evaluate mobile teledermoscopy-enhanced SSE versus naked-eye SSE. Participants in each group will conduct three home whole-body SSEs at baseline, 1 and 2 months, then present for a clinical skin examination (CSE) by a doctor after the 2-month SSE. Specifically, participants will identify skin lesions that meet the AC (asymmetry and colour) rule for detecting a suspicious skin spot. The primary outcomes are sensitivity and specificity of the skin lesions selected by the participants as needing attention by a doctor, compared to the clinical diagnosis by the dermatologist that will serve as the reference standard for this analysis. For the mobile teledermoscopy-enhanced SSE group, researchers will assess the number, location and type of lesions (1) sent by the participant via mobile teledermoscopy, (2) found at CSE or (3) missed by the participant. For the naked-eye SSE group, researchers will assess the number, location and type of lesions (1) recorded on their body chart by the participant, (2) found at CSE or (3) missed by the participant. Secondary outcomes are based on participants’ self-reported data via online questionnaires.

Time resolved optical system for an early detection of prostate tumor

2011 ◽  
Author(s):  
Lionel Hervé ◽  
Aurélie Laidevant ◽  
Mathieu Debourdeau ◽  
Jérôme Boutet ◽  
Jean-Marc Dinten
Keyword(s):  
Early Detection ◽  
Optical System ◽  
Prostate Tumor ◽  
Time Resolved

scholarly journals Raman microspectroscopy for the early detection of pre-malignant changes in cervical tissue

2014 ◽  
Vol 97 (3) ◽  
pp. 554-564 ◽  
Author(s):  
Nosheen Rashid ◽  
Haq Nawaz ◽  
Kelvin W.C. Poon ◽  
Franck Bonnier ◽  
Salih Bakhiet ◽  
...  
Keyword(s):  
Early Detection ◽  
Raman Microspectroscopy ◽  
Cervical Tissue ◽  
Malignant Changes

scholarly journals Design and Experimental Implementation of a Multi-Cloak Paraxial Optical System

Photonics ◽  
2021 ◽  
Vol 8 (9) ◽  
pp. 358
Author(s):  
Alicia Fresno-Hernández ◽  
Braulio García-Cámara ◽  
Juan Carlos Torres ◽  
José Manuel Sánchez-Pena
Keyword(s):  
Visual Field ◽  
Optical System ◽  
Mathematical Formalism ◽  
Transformation Optics ◽  
Lens System ◽  
Successful Operation ◽  
Naked Eye ◽  
Experimental Implementation ◽  
Simple Arrangement ◽  
Simple Systems

Electromagnetic cloaking has being continuously pursued using a large variety of approaches. In recent years, this effect has been observed using either complex devices based on the so-called Transformation Optics or simple systems based on conventional optics with proper characteristics. In the latter case, a simple arrangement of lenses working in the paraxial regime can provide broadband visible cloaking in a wide area. In this work, we analyzed and generalized this method by proposing a five-lens system producing at least three potential invisible regions with a large cloaked area (>90% of the visual field). In particular, we developed the mathematical formalism and show, both numerically and experimentally, the successful operation of the cloaking system with the naked eye.

scholarly journals Spatiotemporal multiplexing method for visual field of view extension in holographic displays with naked eye observation

2016 ◽  
Vol 24 (3) ◽  
Author(s):  
G. Finke ◽  
M. Kujawińska ◽  
T. Kozacki ◽  
W. Zaperty
Keyword(s):  
Visual Field ◽  
Optical System ◽  
Wigner Distribution ◽  
Field Of View ◽  
Distribution Analysis ◽  
Holographic Display ◽  
Holographic Imaging ◽  
Naked Eye ◽  
Holographic Displays ◽  
Functional Problems

AbstractIn this paper we propose a method which allows to overcome the basic functional problems in holographic displays with naked eye observation caused by delivering too small images visible in narrow viewing angles. The solution is based on combining the spatiotemporal multiplexing method with a 4f optical system. It enables to increase an aperture of a holographic display and extend the angular visual field of view. The applicability of the modified display is evidenced by Wigner distribution analysis of holographic imaging with spatiotemporal multiplexing method and by the experiments performed at the display demonstrator.

The Mayo Lung Project for Early Detection and Localization of Bronchogenic Carcinoma: A Status Report

CHEST Journal ◽  
1975 ◽  
Vol 67 (5) ◽  
pp. 511-522 ◽  
Author(s):  
Robert S. Fontana ◽  
David R. Sanderson ◽  
Lewis B. Woolner ◽  
W. Eugene Miller ◽  
Philip E. Bernatz ◽  
...  
Keyword(s):  
Early Detection ◽  
Bronchogenic Carcinoma ◽  
Status Report ◽  
Detection And Localization

Preparation and Properties of CdSiO3: Mn2+, Er3+ Phosphor

2013 ◽  
Vol 873 ◽  
pp. 831-836
Author(s):  
Xiao Fei Qu ◽  
Fang Lin Du ◽  
Li Xin Cao
Keyword(s):  
Uv Light ◽  
Luminescent Properties ◽  
Solid State Method ◽  
Naked Eye ◽  
Afterglow Time ◽  
Method Effects ◽  
State Method ◽  
Intensity Decay ◽  
Co Doped

CdSiO3: Mn2+, Er3+long-lasting phosphor was prepared by the conventional high temperature solid-state method. Effects of the concentration of Mn2+and Er3+on the luminescent properties of phosphor CdSiO3: Mn2+, Er3+were investigated by means of photoluminescence (PL) spectra and the afterglow intensity decay curves. It was found that when the Mn2+and Er3+dopant-concentrations were 0.2 mol% and 0.8 mol% of Cd2+ions in CdSiO3, respectively, the luminescence of phosphor prepared had better luminescent property and longer afterglow time. The phosphorescence for it could be seen with the naked eye for more than 60 min in the dark after the removal of the 254 nm UV light. Role of Er3+co-doped into CdSiO3: Mn2+matrix was discussed in this paper.

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