scholarly journals Diagnostic accuracy of diffuse reflectance imaging for early detection of pre-malignant and malignant changes in the oral cavity: a feasibility study

BMC Cancer ◽  
2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Manju M Stephen ◽  
Jayaraj L Jayanthi ◽  
Nisha G Unni ◽  
Philip E Kolady ◽  
Valappil T Beena ◽  
...  
Keyword(s):  
Early Detection ◽  
Oral Cavity ◽  
Diagnostic Accuracy ◽  
Feasibility Study ◽  
Diffuse Reflectance ◽  
Malignant Changes ◽  
Diffuse Reflectance Imaging

scholarly journals Independent Validation of Sepsis Index for Sepsis Screening in the Emergency Department

Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1292
Author(s):  
Luisa Agnello ◽  
Alessandro Iacona ◽  
Salvatore Maestri ◽  
Bruna Lo Sasso ◽  
Rosaria Vincenza Giglio ◽  
...  
Keyword(s):  
Emergency Department ◽  
High Risk ◽  
Early Detection ◽  
Diagnostic Accuracy ◽  
Positive Likelihood Ratio ◽  
Curve Analysis ◽  
Roc Curve Analysis ◽  
Distribution Width ◽  
Independent Validation ◽  
Sepsis Screening

(1) Background: The early detection of sepsis is still challenging, and there is an urgent need for biomarkers that could identify patients at a high risk of developing it. We recently developed an index, namely the Sepsis Index (SI), based on the combination of two CBC parameters: monocyte distribution width (MDW) and mean monocyte volume (MMV). In this study, we sought to independently validate the performance of SI as a tool for the early detection of patients at a high risk of sepsis in the Emergency Department (ED). (2) Methods: We enrolled all consecutive patients attending the ED with a request of the CBC. MDW and MMV were measured on samples collected in K3-EDTA tubes on the UniCel DxH 900 haematology analyser. SI was calculated based on the MDW and MMV. (3) Results: We enrolled a total of 703 patients stratified into four subgroups according to the Sepsis-2 criteria: control (498), infection (105), SIRS (52) and sepsis (48). The sepsis subgroup displayed the highest MDW (median 27.5, IQR 24.6–32.9) and SI (median 1.15, IQR 1.05–1.29) values. The ROC curve analysis for the prediction of sepsis showed a good and comparable diagnostic accuracy of the MDW and SI. However, the SI displayed an increased specificity, positive predictive value and positive likelihood ratio in comparison to MDW alone. (4) Conclusions: SI improves the diagnostic accuracy of MDW for sepsis screening.

Diagnostic accuracy of different methods of early detection of chronic kidney disease

2017 ◽  
Vol 25 (4) ◽  
pp. 401-407
Author(s):  
Luciana Saraiva da Silva ◽  
Rosângela Minardi Mitre Cotta ◽  
Tiago Ricardo Moreira ◽  
Rodrigo Gomes da Silva
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Early Detection ◽  
Diagnostic Accuracy

Role of Nurses in the Prevention and Early Detection of Oral Cavity and Pharynx Cancers

2021 ◽  
Vol 21 (2) ◽  
pp. 152-166
Author(s):  
Patricia Da Rosa ◽  
Lori Koenecke ◽  
Laura Gudgeon ◽  
Whitney Keller ◽  
Wei Gu
Keyword(s):  
Early Detection ◽  
Oral Cavity ◽  
Prevention And Early Detection

Diagnostic Accuracy of Multislice Contrast CT scan in Detection of Squamous cell Carcinoma of Oral cavity, in clinically suspected Patients

2021 ◽  
Vol 15 (8) ◽  
pp. 2500-2501
Author(s):  
Aliya Khan ◽  
Abid Ali Sahito ◽  
Mahreen Shaikh ◽  
Humera Jabeen ◽  
Humaira Ashraf ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Squamous Cell Carcinoma ◽  
Oral Cavity ◽  
Diagnostic Accuracy ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Gold Standard ◽  
Multislice Computed Tomography ◽  
Multislice Ct ◽  
Sensitivity Specificity

Objective: To evaluate the diagnostic accuracy of multislice computed tomography (CT) in detection of squamous cell carcinoma (SCC) of oral cavity in clinically suspected patients taking histopathology as gold standard. Material and Methods: This cross-sectional study has been conducted at Radiology department of Civil Hospital Karachi from 8th September 2018 to March 2019. All the cases having suspected oral squamous cell carcinoma and either of gender were included. Patients underwent computed tomography by using multislice scanner. Then patients undergone biopsy sampling and patients were labeled as positive or negative for squamous cell carcinoma of oral cavity on MDCT and histopathology. Sensitivity, specificity, and diagnostic accuracy of multislice CT for squamous cell carcinoma of oral cavity were measured taking histopathology as gold standard. Results: Total 168 cases were studied and out of them males were 76.8% and females were 23.2%. Mean gutka addiction history was 11.52±5.21 years. Mean lesion size on CT scan was 2.44±1.43 cm. In our study, 35.1% patients were diagnosed positive by multislice computed tomography and 43.5% through histopathology. Sensitivity, Specificity, PPV, NPV and accuracy were 86.4%, 79.8%, 69.9%, 91.6%, and 82.1% respectively. Conclusion: Multislice CT observed to be the effective diagnostic tool for the detection of SCC of oral cavity. Keywords: Multislice Computed Tomography, cancer, Oral Cavity

scholarly journals Primary Oral Malignant Melanoma: Two Case Reports and Review of Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Neeraj Sharma
Keyword(s):  
Malignant Melanoma ◽  
Early Detection ◽  
Oral Cavity ◽  
Tumor Size ◽  
Malignant Tumors ◽  
Case Reports ◽  
Review Of Literature ◽  
Oral Region ◽  
Rare Neoplasm ◽  
Oral Malignant Melanoma

Primary malignant melanoma of the oral cavity is a rare neoplasm. The tumors tend to metastasize or locally invade tissue more readily than other malignant tumors in the oral region. The survival of patients with mucosal melanomas is less than for those with cutaneous melanomas. Tumor size and metastases are related to the prognosis of the disease. Early detection, therefore, is important.

Sign in / Sign up

Export Citation Format

Share Document