scholarly journals Borderline personality disorder and polycystic ovary syndrome: A review of the literature

2017 ◽  
Vol 52 (2) ◽  
pp. 117-128 ◽  
Author(s):  
Raelene YM Tan ◽  
Jasmin Grigg ◽  
Jayashri Kulkarni
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Case Reports ◽  
Borderline Personality ◽  
Polycystic Ovaries ◽  
Ovary Syndrome ◽  
Cross Sectional ◽  
The Relationship

Objective: This review examines the existing evidence for the relationship between borderline personality disorder and polycystic ovary syndrome, and to identify commonalities in etiological mechanisms of borderline personality disorder and polycystic ovary syndrome that might explain the relationship between these seemingly disparate disorders. Methods: A search of Medline, EMBASE and Cochrane Central was undertaken on 5 December 2016 to identify studies investigating women with borderline personality disorder and polycystic ovary syndrome (or symptoms and markers specific to polycystic ovary syndrome). Results: Nine studies were identified, including three cross-sectional studies investigating symptoms of polycystic ovary syndrome in women with borderline personality disorder, two cross-sectional and one cohort study examining the prevalence of psychiatric diagnoses in women with polycystic ovary syndrome and three case reports of comorbid borderline personality disorder and polycystic ovary syndrome. Conclusion: Overall, the literature shows women with borderline personality disorder to have higher than expected serum androgen levels and incidence of polycystic ovaries, which can be key features of polycystic ovary syndrome. However, this research is still in its infancy, which limits our understanding of this potential comorbid phenomenon. Given the emerging anecdotal and empirical evidence to date, a theoretical discussion of the potential psychoneuroendocrinological mechanism underlying the borderline personality disorder and polycystic ovary syndrome comorbidity is provided. Further rigorous studies using standardized diagnostic criteria for polycystic ovary syndrome are warranted. Specifically, the use of prospective controlled cohort studies may be able to determine the causality and temporality of observed comorbid borderline personality disorder and polycystic ovary syndrome.

scholarly journals Circulating leptin concentrations and ovarian function in polycystic ovary syndrome

2001 ◽  
pp. 289-294 ◽  
Author(s):  
IR Pirwany ◽  
R Fleming ◽  
N Sattar ◽  
IA Greer ◽  
AM Wallace
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Ovarian Function ◽  
Polycystic Ovary ◽  
Ovarian Dysfunction ◽  
Ovary Syndrome ◽  
Cross Sectional ◽  
Serum Leptin ◽  
Significant Difference ◽  
The Relationship

OBJECTIVE: Polycystic ovary syndrome (PCOS) is characterized by ovarian dysfunction. Although the role of leptin in the control of reproduction is unclear, it may be involved in the control of ovulation. The aim of this cross-sectional study was to determine the relationship between circulating leptin concentrations, and anthropometric, metabolic and endocrine variables as well as to examine a possible role of leptin in ovarian dysfunction associated with PCOS. DESIGN: Prospective observational study. METHODS: Seventy-one subjects with PCOS and 23 body mass index (BMI)-matched control subjects were recruited from infertility clinics. The association between serum leptin concentrations and the above variables was measured outwith the luteal phase. A subgroup of 24 PCOS subjects underwent more frequent blood sampling to monitor follicular growth and ovulation. The association between variables was measured by univariate, multivariate and partial correlation analyses. RESULTS: Serum leptin concentrations were not different in subjects with PCOS and controls, and were strongly associated with BMI in both groups. Twelve patients ovulated during the study period. There was no significant difference in serum leptin concentrations between ovulatory and anovulatory subjects. The relationship between BMI and leptin was similar in both groups. CONCLUSION: The results indicated that circulating leptin concentrations relate principally to total body fat in subjects with PCOS and controls, and that this is not associated with the facility for follicular development and ovulation in these patients.

scholarly journals Asthma in reproductive-aged women with polycystic ovary syndrome and association with obesity

2017 ◽  
Vol 49 (5) ◽  
pp. 1601334 ◽  
Author(s):  
Thaw D. Htet ◽  
Helena J. Teede ◽  
Barbora de Courten ◽  
Deborah Loxton ◽  
Francisco G. Real ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Odds Ratio ◽  
Polycystic Ovary ◽  
Smoking Status ◽  
Epidemiological Studies ◽  
Community Based ◽  
Ovary Syndrome ◽  
Cross Sectional ◽  
Reproductive Aged Women ◽  
The Relationship

Recent research suggests that women with polycystic ovary syndrome (PCOS) may have a higher prevalence of asthma. However, there are no epidemiological studies aimed primarily at exploring the relationship between PCOS and asthma, and the effect of body mass index (BMI) on this association.This study is a cross-sectional analyses of data from the Australian Longitudinal Study on Women's Health, a large, community-based, prospective study to examine the association between PCOS and asthma in women aged 28–33 years (n=478 PCOS and n=8134 controls).The prevalence of asthma was 15.2% in women with PCOS and 10.6% in women without PCOS (p=0.004). Women with PCOS who had asthma had a trend for a higher BMI compared with women without asthma (29.9±0.9 versus 27.7±0.4 kg·m−2; p=0.054). Women without PCOS who had asthma had a higher BMI compared with women without asthma (26.4±0.2 versus 24.9±0.1 kg·m−2; p<0.001). After adjusting for age, BMI and smoking status, PCOS was associated with increased odds of asthma (odds ratio 1.34, 95% CI 1.004–1.79; p=0.047).This study showed both PCOS status and overweight/obese status were independently associated with asthma. Further prospective studies are required to explore the possible mechanisms underpinning the association between asthma and PCOS.

scholarly journals Does body mass index have an effect on the prevalence of various symptoms of polycystic ovary syndrome and their associated risk factors?

2021 ◽  
Vol 84 (2) ◽  
pp. 101-116
Author(s):  
Raminder Kaur ◽  
Maninder Kaur ◽  
Vanita Suri
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Polycystic Ovary Syndrome ◽  
Body Mass ◽  
Polycystic Ovary ◽  
Activity Level ◽  
Polycystic Ovaries ◽  
Ovary Syndrome ◽  
Cross Sectional ◽  
Associated Risk Factors

Abstract The present cross-sectional study is an attempt to understand the effect of body mass index (BMI) on the prevalence of various symptoms of polycystic ovary syndrome (PCOS) and to evaluate its associated risk factors. A total of 250 PCOS women diagnosed by Rotterdam Criteria (2003), age ranging from 18–45 years, attending OPD of Gynaecology and Obstetrics of PGIMER, Chandigarh, India were enrolled in the study. All the participants were divided in three groups according to their body mass index (BMI). The polycystic ovaries (83.2%) were the most frequently occurring symptoms of PCOS followed by hirsutism (74.4%), oligomenorrhea (60%), seborrhea (45.2%) and acne (40%). Category wise frequency distribution showed higher prevalence of symptoms among women in overweight/obese category, which were further supported by correspondence analysis. Results of multivariate analysis revealed that marital status, type of diet, socio-economic status and physical activity level were potential risk factors contributing to severe manifestations of PCOS symptoms. Obesity denoted as an important risk factor can exaggerate many symptoms of PCOS and also be a causative factor for menstrual disturbance.

scholarly journals Anti-mullerian hormone is associated with advanced glycosylated end products in lean women with polycystic ovary syndrome

2009 ◽  
Vol 160 (5) ◽  
pp. 847-853 ◽  
Author(s):  
Evanthia Diamanti-Kandarakis ◽  
Athanasia Piouka ◽  
Sarantis Livadas ◽  
Christine Piperi ◽  
Ilias Katsikis ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Oocyte Maturation ◽  
Granulosa Cells ◽  
Polycystic Ovary ◽  
Cross Sectional Study ◽  
Ovary Syndrome ◽  
Cross Sectional ◽  
End Products ◽  
Normal Women ◽  
The Relationship

ObjectiveOocyte maturation process characterizes polycystic ovary syndrome (PCOS). The mechanisms of this abnormality leading to chronic anovulation are under investigation. Advanced glycosylated end products (AGEs), a marker of oxidative stress linked with oocyte maturation are localized in granulosa cells and are increased in sera, in women with PCOS. The aim of this study was to investigate the relationship, whether there is an association between the anti-mullerian hormone (AMH), a hormone produced by granulosa cells and AGEs in ovulatory and anovulatory PCOS (PCOS-Anov), as well as in non-PCOS anovulatory (Non-PCOS Anov) women.DesignCross-sectional study.MethodsData from sixty women with PCOS (37 anovulatory and 23 regularly ovulating) were compared with eleven Non-PCOS Anov women and 25 normal women. In each subject biochemical, hormonal, and ultrasonographic parameters were studied.ResultsAMH values were statistically significantly higher in PCOS-Anov (7.63±3.12) in comparison with ovulatory PCOS (PCOS-Ov; 4.92±2.50), Non-PCOS Anov (3.66±1.4), and controls (4.02±1.27 ng/ml). AGEs demonstrated a similar pattern: 8.70±1.65 in PCOS-Anov, 7.43±1.79, PCOS-Ov, 5.21±0.09, Non-PCOS Anov, and 5.85±0.89 U/ml in controls (P<0.005 for all comparison respectively). Follicle number was significantly higher in PCOS-Anov in comparison with other groups. A significant positive correlation between AMH and AGEs was observed (r: 0.326,P<0.01), and with the estimated AMH/AGEs ratio to follicle number (r: 0.42,P: 0.0001) and the presence of anovulation.ConclusionsThese data suggest that an oxidative marker, AGEs, and AMH, may interact in the anovulatory mechanisms in women with PCOS.

Borderline Personality Disorder and Religiosity: Exploring the Relationship

2019 ◽  
Vol 46 (2) ◽  
pp. 40-56
Author(s):  
Lisa Hosack
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Undergraduate Students ◽  
Religious Faith ◽  
Cross Sectional Study ◽  
Borderline Personality ◽  
Negative Effects ◽  
Cross Sectional ◽  
Relationship Of ◽  
The Relationship

The negative effects of borderline personality disorder (BPD) are widely documented. And while religiosity has been found to be generally beneficial for individuals with clinical disorders, little is known about the relationship of religiosity and personality disorders, including BPD.  The purpose of this quantitative, cross-sectional study was to examine the relationship between BPD and two important components of religiosity. The first was termed religious quest and was defined in the study as the level of one’s internal openness to faith and spirituality. The other was defined as religious engagement and was defined in the study as the external, behavioral marks of religious faith such as prayer and attendance at religious events. A survey comprised of several validated measures was administered to undergraduate students within a large public university in the Midwest (N = 466).

scholarly journals Is polycystic ovary syndrome appropriately diagnosed by obstetricians and gynaecologists across China: a nationwide survey

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Deng Yan ◽  
Wang Yan-Fang ◽  
Zhu Shi-Yang ◽  
Ma Rui-Lin ◽  
Ding Xue-Song ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Diagnostic Criteria ◽  
Polycystic Ovary ◽  
Final Analysis ◽  
Nationwide Survey ◽  
Care Quality ◽  
Cross Sectional Survey ◽  
Ovary Syndrome ◽  
Cross Sectional ◽  
Rotterdam Criteria

Abstract Background To describe the diagnostic criteria used and their application accuracy in the practice of polycystic ovary syndrome (PCOS) caring among obstetricians and gynaecologists across China. Methods This was an Online cross-sectional survey of Obstetricians and gynecologists involved in PCOS caring conducted via the largest continuing education platform of obstetrics and gynecology across China from September 2019 to November 2019. Results A total of 2,328 respondents were eligible for the final analysis. Of these, 94.5 % were general obstetricians and gynaecologists (Ge-ObGyn), and 5.5 % were reproductive endocrinologists (Re-ObGyn). Overall, the most frequently used criteria were the Androgen Excess and Polycystic Ovary Syndrome Society (AE-PCOS) criteria (48.2 %), followed by the Rotterdam criteria (35.7 %) and NIH criteria (12.1 %). Of the respondents, 31.3 % used their diagnostic criteria in their clinical practice. More respondents who chose the Rotterdam criteria could accurately apply the diagnostic criteria than those who chose the AE-PCOS criteria (41.2 % vs. 32.1 %, P < 0.001). Compared with Ge-ObGyn, Re-ObGyn were less likely to use the AE-PCOS criteria (adjusted odds ratio, 0.513; 95 % CI, 0.328–0.802; P < 0.05) and 1.492 times more likely to accurately use their criteria (95 % CI, 1.014–2.196; P < 0.05). Conclusions Less than one-third of obstetricians and gynaecologists across China could accurately use the diagnostic criteria they choose to diagnose PCOS. There is an urgent need to train obstetricians and gynaecologists on PCOS diagnosis in an effort to improve the medical care quality of patients with PCOS.

Sign in / Sign up

Export Citation Format

Share Document