Eosinophilic Gastroenteritis Presenting as Acute Intestinal Obstruction

1983 ◽  
Vol 28 (2) ◽  
pp. 183-184 ◽  
Author(s):  
R. J. C. Steele ◽  
R. G. Wright ◽  
H. M. Gilmore
Keyword(s):  
Small Intestine ◽  
Abdominal Pain ◽  
Intestinal Obstruction ◽  
Large Intestine ◽  
Eosinophilic Gastroenteritis ◽  
Acute Intestinal Obstruction ◽  
Clinical Feature ◽  
Distal Small Intestine ◽  
Uncommon Condition ◽  
Small Intestinal

Eosinophilic gastroenteritis is an uncommon condition which usually affects the antrum of the stomach and may occasionally involve the small or large intestine (1). The main clinical feature is usually that of chronic colicky abdominal pain. We report a case presenting as acute small intestinal obstruction due to isolated involvement of the distal small intestine.

CHANGES IN SMALL INTESTINE MICROFLORA IN PATIENTS WITH ACUTE INTESTINAL OBSTRUCTION

2020 ◽  
pp. 16-18
Author(s):  
V. M. Lykhman ◽  
O. M. Shevchenko ◽  
Ye. O. Bilodid ◽  
Igor Vladimirovich Volchenko ◽  
I. A. Kulyk ◽  
...  
Keyword(s):  
Small Intestine ◽  
Gastrointestinal Tract ◽  
Species Composition ◽  
Intestinal Obstruction ◽  
Bacterial Flora ◽  
Anaerobic Bacteria ◽  
Acute Intestinal Obstruction ◽  
Gram Positive ◽  
Mechanical Intestinal Obstruction ◽  
Facultative Anaerobic Bacteria

Among urgent surgical diseases of abdominal cavity, an acute intestinal obstruction is the most difficult to be diagnosed and treated. Leading factor, determining the development of pathophysiological processes is considered to be the progressive manifestations of enteric insufficiency syndrome, resulting in intestinal barrier impairment, negative changes in ecology of intestinal flora, increased endotoxins. To identify the small intestine microflora in acute intestinal obstruction and determine the role of dysbiotic disorders in clinical manifestations of main pathological process, a study was conducted in 60 patients with mechanical intestinal obstruction. The small intestine has a relatively rare microflora, consisting mainly of gram−positive facultative aerobic microorganisms, streptococci, lactobacilli. The distal ileum in nearly 30−55 % of healthy people contains scanty microflora, and yet the flora of this area differs from the microbial population of the higher gastrointestinal tract due to higher concentration of gram−negative bacteria. Optional−anaerobic coliform bacilli, anaerobic bifidobacteria and fusobacteria, bacteroids, the number of which starts exceeding the one of gram−positive species, are presented in significant quantities. Distal to the ileocecal valve there are significant changes in the microflora quantitative and species composition. Obligatory anaerobic bacteria become the predominant part of microflora, exceeding the number of aerobic and facultative anaerobic bacteria. The bacterial flora in different parts of gastrointestinal tract has its own specifics and is quite constant, as a result of the interaction of many factors, regulating the bacterial population in small intestine. The most important among them are: acidity of gastric juice, normal peristaltic activity of the intestine, bacterial interactions and immune mechanisms. Disorders of the intestine motor and evacuation function with its obstruction lead to slow passage of the chyme and contamination of the upper gastrointestinal tract with new types of microbes. There is a syndrome of small intestine excessive colonization, which means an increased concentration of bacterial populations in it, similar in species composition to the colon microflora. Pathological intra−intestinal contents become a source of endogenous infection and re−infection of the patient, leads to internal digestive disorders, which is manifested by syndrome of malabsorption of proteins, carbohydrates and vitamins. Key words: acute intestinal obstruction, small intestinal microflora, conditionally pathogenic microorganisms, intestinal biocenosis.

Pathology of Infectious Diarrhea of Infant Rats (IDIR) Induced by an Antigenically Distinct Rotavirus

1989 ◽  
Vol 26 (5) ◽  
pp. 376-385 ◽  
Author(s):  
A. C. Huber ◽  
R. H. Yolken ◽  
L. C. Mader ◽  
J. D. Strandberg ◽  
S. L. Vonderfecht
Keyword(s):  
Small Intestine ◽  
Post Inoculation ◽  
Diagnostic Features ◽  
Distal Small Intestine ◽  
Precursor Material ◽  
Viral Particles ◽  
Intestinal Segments ◽  
Villous Height ◽  
Small Intestinal ◽  
Group B

Suckling rats were inoculated with a group B rotavirus to determine the progression of the morphologic changes induced in the intestine by this virus. Several changes were observed by light microscopy 1 day after viral inoculation: shortening of small intestinal villi, villous epithelial necrosis, and villous epithelial syncytia. The lesions were most often present in the distal small intestine, although other small intestinal segments were affected to a lesser degree. By day 3 post-inoculation, epithelial necrosis, and syncytia were no longer present; however, the villous epithelium was disorganized and irregularly vacuolated, and intestinal crypt epithelium was hyperplastic. Alterations in villous height to crypt depth ratios were present in portions of the small intestine for the remainder of the 12-day study period. Epithelial syncytia appeared to form by the breakdown of the lateral interdigitating membranes of the absorptive villous epithelium. Viral particles, abundant in the syncytia, appeared to form from amorphous or reticular arrays of viral precursor material. Group B rotaviral antigens, as detected by indirect immunofluorescence, were present in large amounts in the small intestinal villous epithelium only on the first day after viral inoculation. These studies show that two important diagnostic features of group B rotaviral infections of rats, epithelial syncytia and viral antigen as determined by immunofluorescence, are present only on the first day of disease. These findings should be taken into consideration when attempting to diagnose disease induced by this agent.

Intestinal Obstruction Caused by Taenia taeniaeformis Infection in a Cat

2009 ◽  
Vol 45 (2) ◽  
pp. 93-96 ◽  
Author(s):  
Rebbecca S. Wilcox ◽  
Dwight D. Bowman ◽  
Stephen C. Barr ◽  
James M. Euclid
Keyword(s):  
Intestinal Obstruction ◽  
Medical Management ◽  
Clinical Status ◽  
Acute Intestinal Obstruction ◽  
Surgical Removal ◽  
Small Intestinal Obstruction ◽  
Small Intestinal ◽  
Taenia Taeniaeformis ◽  
First Time

An adult domestic shorthair (DSH) cat was presented with acute vomiting, anorexia, lethargy, and dyspnea. The cat’s clinical status worsened over 24 hours with conservative medical management. An exploratory celiotomy was performed. Acute intestinal obstruction resulting from infection with Taenia (T.) taeniaeformis was diagnosed. Surgical removal of the cestodes via multiple enterotomies resolved the obstruction. This paper reports, for the first time, small intestinal obstruction caused by T. taeniaeformis infection in a cat.

scholarly journals Human intestinal glutathione S-transferases

1989 ◽  
Vol 257 (2) ◽  
pp. 471-476 ◽  
Author(s):  
W H M Peters ◽  
H M J Roelofs ◽  
F M Nagengast ◽  
J H M van Tongeren
Keyword(s):  
Small Intestine ◽  
Large Intestine ◽  
Specific Activity ◽  
Distal Colon ◽  
Glutathione S Transferase ◽  
Distal Small Intestine ◽  
Cytosolic Glutathione ◽  
Glutathione S Transferases ◽  
Isoenzyme Composition ◽  
Specific Activities

Cytosolic glutathione S-transferases were purified from the epithelial cells of human small and large intestine. These preparations were characterized with regard to specific activities, subunit and isoenzyme composition. Isoenzyme composition and specific activity showed little variation from proximal to distal small intestine. Specific activities of hepatic and intestinal enzymes from the same patient were comparable. Hepatic enzymes were mainly composed of 25 kDa subunits. Transferases from small intestine contained 24 and 25 kDa subunits, in variable amounts. Colon enzymes were composed of 24 kDa subunits. In most preparations, however, minor amounts of 27 and 27.5 kDa subunits were detectable. Separation into isoforms by isoelectric focusing revealed striking differences: glutathione S-transferases from liver were mainly basic or neutral, enzymes from small intestine were basic, neutral and acidic, whereas large intestine contained acidic isoforms only. The intestinal acidic transferase most probably was identical with glutathione S-transferase Pi, isolated from human placenta. In the hepatic preparation, this isoform was hardly detectable. The specific activity of glutathione S-transferase showed a sharp fall from small to large intestine. In proximal and distal colon, activity seemed to be about equal. In the ascending colon there might be a relationship between specific activity of glutathione S-transferases and age of the patient, activity decreasing with increasing age.

Ammonia in the large intestine of herbivores

1971 ◽  
Vol 26 (2) ◽  
pp. 135-145 ◽  
Author(s):  
J. F. Hecker
Keyword(s):  
Small Intestine ◽  
Large Intestine ◽  
Free Amino ◽  
Amino Nitrogen ◽  
Ammonia Concentration ◽  
Intestinal Contents ◽  
Rate Of Absorption ◽  
Small Intestinal

1. The object was toinvestigate the importance of urea a source of ammonia in the large intestine of herbivores. Urea was present in small intestinal contents of slaughtered horses in concentrations similar to those in blood but, in the small intestine of salughtered sheep, the urea was less than in blooc.2. There was little ammonia in small intestinal contents of slaughtered horses but consider-able ammonia was present in small intestinal contents of slaughtered sheep. The ammonia in small intestinal contents of the slaughtered sheep was probably formed from urea, as ileal con-tents taken from a sheep with an ileal cannula contained considerable urea and little ammonia.3. The ammonia concentration in caecal contents of sheep was related to the concentration of urea in blood except when ileal contents were prevented from entering the caecum.4. Ileal digesta of sheep contained more free amino nitrogen than did caecal digesta.5. Ammonia was absorbed more rapidly than water from the caecum of sheep. The rate of absorption was related to the concentration of ammonia in the caecum.

scholarly journals INTESTINAL INVAGINATION OF ADULT

2018 ◽  
Vol 5 (3) ◽  
pp. 117-120
Author(s):  
B. Abdullajonov ◽  
F. Nishanov ◽  
B. Madvaliyev ◽  
A. Nuriddinov ◽  
A. Rustamjonov ◽  
...  
Keyword(s):  
Small Intestine ◽  
Intestinal Obstruction ◽  
Key Words ◽  
Emergency Surgery ◽  
Research Work ◽  
Acute Intestinal Obstruction ◽  
Acute Peritonitis ◽  
Intestinal Invagination

INTESTINAL INVAGINATION OF ADULTSAbdullajonov B., Nishanov F., Madvaliyev B.,Nuriddinov А., Rustamjonov A., Mishenina K. Authors presents analyze with literature for questions about spread, etiology, pathogenesis, main clinic and treats intestinal invagination of adults – less forms of acute intestinal obstruction. Given research work of patient with intestinal invagination. Key words: intestinal obstruction, invagination of small intestine, acute peritonitis, emergency surgery. РезюмеІНВАГІНАЦІЯ КИШКІВНИКА У ДОРОСЛИХАбдуллажанов Б., Нішанов Ф., Мадавлієв Б.,Нуріддін А., Рустамжонов А., Мішеніна К.Авторами представлені аналіз літератури з питань поширення, етіології, патогенезу, особливостей клініки та лікування інвагінації кишківника у дорослих - рідкісної форми гострої кишкової непрохідності.Наведено аналіз історії хвороби хворого наінвагінацію тонкого кишківника.Ключові слова: кишкової непрохідності, інвагінації тонкого кишківника, гострий перитоніт, екстрена хірургія. РезюмеИНВАГИНАЦИЯ КИШЕЧНИКА У ВЗРОСЛЫХАбдуллажанов Б., Нишанов Ф., Мадавлиев Б., Нуриддинов А., Рустамжонов А., Мишенина Е.Авторами представлены анализ литературы по вопросам распространения, этиологии, патогенеза, особенностей клиники и лечения инвагинации кишечника у взрослых - редкой формы острой кишечной непроходимости. Приведен анализ истории болезни больной с инвагинацией тонкого кишечника. Ключевые слова: кишечной непроходимости, инвагинацией тонкого кишечника, острый перитонит, экстренная хирургия. 

scholarly journals Experimental substantiation of using a synthetic peptide in the complex surgical treatment of acute intestinal obstruction

2018 ◽  
pp. 138-140
Author(s):  
А.А. Коваленко ◽  
В.К. Хугаева
Keyword(s):  
Surgical Treatment ◽  
Intestinal Obstruction ◽  
Intestinal Anastomosis ◽  
Intestinal Wall ◽  
Acute Intestinal Obstruction ◽  
Study Objective ◽  
Doppler Flowmetry ◽  
Study Results ◽  
Small Intestinal

Высокая смертность при хирургическом лечении острой кишечной непроходимости (ОКН) определила поиск новых методов сопутствующей терапии. Обнаруженная ранее высокая эффективность опиоидных пептидов в стимулировании лимфотока в микрососудах брыжейки тонкой кишки у крыс, восстановлении нарушенной микроциркуляцию и снижении смертности при ряде заболеваний, определила цель данного исследования: изучить роль фармакологической стимуляции лимфотока в динамике ОКН. В работе использовали методы: биомикроскопия, лазерная допплеровская флоуметрия брыжейки и стенки тонкой кишки крысы, регистрация сократительной активности лимфатических микрососудов ЛМ методом фотометрии, морфометрия микрососудов, видео- и фотосъемка. Полученные результаты предполагают наличие адаптационной роли у активатора микролимфоциркуляции (опиоидного пептида-171 прямого действия) в комплексном хирургическом лечении ОКН. Однократное орошение пептидом межкишечного анастомоза (после удаления) и поврежденного лигатурой фрагмента кишки (перед зашиванием операционной раны) увеличивало выживаемость животных с ОКН на 23%. У всех выживших животных отмечено восстановление: проходимости кишки, микроциркуляции в кровеносных и лимфатических микрососудах, а также структуры стенки кишки. High mortality in the surgical treatment of acute intestinal obstruction (AIO) has warranted the search for new methods of concomitant therapy. Opioid peptides have proved highly effective in stimulating the lymphatic flow in rat small intestinal mesenteric microvessels, restoring the impaired microcirculation, and reducing mortality in many diseases. This had determined this study objective: to investigate the role of lymphatic stimulation in the dynamics of AIO. The study used methods of biomicroscopy, laser Doppler flowmetry, and histological examination of the mesentery and the small intestinal wall in rats; recording the contractile activity of lymphatic microvessels using photometry; microvessel morphometry; video and photography. The study results suggested an adaptive role of the lymphatic microcirculation activator (direct-action opioid-171) in the complex surgical treatment of AIO. A one-time peptide irrigation of the intestinal anastomosis (after removal) and the intestinal injuried by the ligature (before the surgical wound was sutured) increased the survival of animals with AIO by 23%. In all surviving animals, recovery of the intestinal patency, blood and lymphatic microcirculation, and the intestinal wall structure was observed.

scholarly journals Clinical study of adhesion obstruction at a tertiary care hospital: a prospective observational study

2021 ◽  
Vol 8 (4) ◽  
pp. 1201
Author(s):  
Iqbal Saleem Mir ◽  
Younis Bashir ◽  
Yaser Hussain Wani ◽  
Younis Dar ◽  
Shiwani Thakur ◽  
...  
Keyword(s):  
Observational Study ◽  
Intestinal Obstruction ◽  
Surgical Procedure ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Abdominal Distension ◽  
Acute Intestinal Obstruction ◽  
Predisposing Factors ◽  
Clinical Feature ◽  
Care Hospital

Background: Adhesion obstruction is one of the most common presentations of acute abdomen and an important cause of general surgical consultation. This study aimed to analyse demographic features, clinical features, predisposing factors, and management of this surgical problem.Methods: The present study was a prospective observational study and was conducted in the Department of General Surgery of SMHS hospital entitling 267 patients who were diagnosed and treated over 5 years from May 2014 to April 2019.Results: The most common age group diagnosed with acute intestinal obstruction was between 31 to 40 years, with the incidence more in males (65.5%) as compared to females (34.4%). The most common clinical feature was abdominal pain (98.1%) followed by vomiting (93.6%), constipation (86.1%) abdominal distension (82.3%). Postoperative adhesions (40.07%) followed by obstructed hernias (23.3%) and malignancies (14.6%) were the most common predisposing factors. Ischemia was the most common complication in 11.2% of patients followed by necrosis at 6.7% and perforation at 2.9%. Adhesiolysis was the most common surgical procedure performed 43.8% followed by anatomical repair 21.7% and resection and end to end anastomosis 15.3%, enterotomy 10.86%, and Hartman’s procedure 8.2%.Conclusions: Adhesive intestinal obstruction is an important surgical emergency. Post-operative adhesions remain the most common cause of acute intestinal obstruction, with patients most commonly presenting with pain abdomen, all necessary steps must be taken to lessen the chances of adhesions after any surgical procedure.

scholarly journals Spontaneous Transmural Migration of a Retained Surgical Mop into the Small Intestinal Lumen Causing Sub-Acute Intestinal Obstruction: A Case Report

2011 ◽  
Vol 19 (1) ◽  
pp. 34-37
Author(s):  
Md Moniruzzaman Sarker ◽  
AKM Golam Kibria ◽  
Md Manzurul Haque ◽  
Kali Prosad Sarker ◽  
Md Khalilur Rahman
Keyword(s):  
Intestinal Obstruction ◽  
Acute Intestinal Obstruction ◽  
Intestinal Lumen ◽  
College Hospital ◽  
Medical College ◽  
Transmural Migration ◽  
History Of ◽  
Small Intestinal ◽  
The Right ◽  
Surgery Department

A case of sub-acute intestinal obstruction due to spontaneous complete transmural migration of a retained surgical mop into the small intestinal lumen has been treated surgically in surgery department of Rajshahi Medical College Hospital. The patient presented with colicky abdominal pain, nausea, occasional abdominal distention and vomiting. She had history of abdominal operation twice previously. Abdominal examination revealed a mobile lump in the right side of abdomen. Diagnosis could be made only at laparotomy.   doi: 10.3329/taj.v19i1.3167 TAJ 2006; 19(1): 34-37

scholarly journals STUDY OF SURGICAL MANAGEMENT OF INTESTINAL OBSTRUCTION FROM CENTRAL INDIA: A CROSS SECTIONAL STUDY

2021 ◽  
Vol 10 (3) ◽  
pp. 3070-3073
Author(s):  
Samadhan Patil
Keyword(s):  
Abdominal Pain ◽  
Intestinal Obstruction ◽  
Surgical Management ◽  
Central India ◽  
Signs And Symptoms ◽  
Tertiary Hospital ◽  
Acute Intestinal Obstruction ◽  
Postoperative Adhesions ◽  
Cross Sectional ◽  
Mortality And Morbidity

Intestinal obstruction is a common surgical emergency with high mortality and morbidity rates. About 15% of all emergency room visits for acute abdominal pain are due to intestinal obstruction. Acute intestinal obstruction may manifest in a variety of ways, from a relatively normal appearance with only minor abdominal pain and distension to a condition of hypovolemic or septic shock (or both) that necessitates an emergency procedure. In present study we aimed to evaluate surgical management of intestinal obstruction at our tertiary hospital. The current research included patients aged 21 to 80 who had an acute intestinal obstruction that was surgically treated. After initial resuscitation, patients with strong signs and symptoms of acute obstruction were treated with an appropriate surgical procedure. All of the information was recorded in a preformat and analysed using descriptive statistics. 144 patients had surgery for acute intestinal obstruction during the study period. 51 to 60 years old was the most common age group (26 %), followed by 41 to 50 years old (21 %). In a ratio of 2.8:1, male patients were more frequently affected than female patients. Previous abdominal surgery (56 %), diabetes (31 %), smoking (25 %), hypertension (24 %), and bronchial asthma/ COPD (15 %) were all found to be common comorbidities in this research. Postoperative adhesions (47 %), malignancy (15 %), obstructed hernia (11 %), and Koch's abdomen were the most common causes of intestinal obstruction in this report (8 %). Adhesiolysis (47 %), resection and anastomosis (22 %), diversion colostomy (13 %), and hernioplasty were the most common surgical procedures in this study (11 %). The most common post-operative complications were fever (15%) and wound infection (11%) respectively. The post-operative mortality rate was 13%. (9 patients). Complications such as septicaemia, peritonitis, and respiratory infection account for the majority of deaths. Intestinal obstruction is often caused by postoperative adhesions. Early operative procedures, in combination with clinical diagnosis and radiological findings, may enhance the outcome of acute intestinal obstruction.

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