The Australian Polidocanol (Aethoxysklerol) Study: Results at 1 Year

1994 ◽  
Vol 9 (1) ◽  
pp. 17-20 ◽  
Author(s):  
P. Conrad ◽  
G. M. Malouf ◽  
M. C. Stacey
Keyword(s):  
Side Effects ◽  
Prospective Study ◽  
Hypertonic Saline ◽  
Varicose Veins ◽  
Previous Experience ◽  
Private Practices ◽  
Sclerosing Agents ◽  
Study Results ◽  
Sodium Tetradecyl Sulphate ◽  
Spider Veins

Objective: To evaluate the complications of polidocanol and compare its effectiveness and complications with sodium tetradecyl sulphate (STD) and hypertonic saline. Design: A single-arm prospective study of polidocanol complications and its effectiveness as a sclerosant. This was compared with each investigator's previous experience with other sclerosing agents. Setting: Multiple investigators in both private practices and hospital settings. Patients: Patients had either varicose veins or venule ectasias and/or spider veins (telangiectasia). A total of 8177 limbs were injected by 75 investigators. Interventions: Sclerotherapy was performed with 0.5% or 1% polidocanol for telangiectasias or spider veins, and with 3% polidocanol for varicose veins. The effectiveness of the sclerotherapy and any complications were reported during a 12-month period. Results: There were very few complications reported with polidocanol. There were no reported deaths or anaphylaxis. The investigators with previous experience of other sclerosants considered that the effectiveness of polidocanol was superior to STD (77%) and hypertonic saline (75%). Ninety-one per cent of investigators considered that polidocanol had less frequent complications than STD, and 96% considered that these were less severe. Sixty-nine per cent considered that polidocanol had fewer side-effects than hypertonic saline, and 71% considered that these were less severe. Conclusions: Polidocanol is an effective sclerosant that has few complications.

scholarly journals Saphenion®: Oxygen Multi-Step Therapy in Varicose Veins: Improvement of the Microcirculation- Our Prospective Study Results in 118 Cases Over 6 Months

2021 ◽  
Vol 6 (2) ◽  
pp. 1-5
Author(s):  
Ulf Thorsten Zierau ◽  
Keyword(s):  
Blood Pressure ◽  
High Pressure ◽  
Prospective Study ◽  
Skeletal Muscles ◽  
Varicose Veins ◽  
Human Organism ◽  
Cardiac Work ◽  
Intellectual Work ◽  
Study Results ◽  
Step Therapy

Oxygen multi-step therapy for Varicose Veins: Oxygen as an energy carrier, all mechanisms in the human organism during growth, its maintenance and its physical and mental activity require energy. This becomes particularly clear to the patient during cardiac work, breathing work in the lungs, skeletal muscles and intellectual work. The pathology of the microcirculation in the capillaries depends largely on the oxygen partial pressure and on the blood pressure in the supplying arteries and the high pressure in the draining veins.

scholarly journals COMPARISON OF INTRALESIONAL SCLEROTHRERAPY WITH BLEOMYCIN VS SODIUM TETRA DECYL SULPHATE IN LYMPHANGIOMA

2020 ◽  
pp. 1-3
Author(s):  
Janki Bisht ◽  
Akshay Prasad
Keyword(s):  
Prospective Study ◽  
Lower Limb ◽  
Vascular Lesions ◽  
Intralesional Injection ◽  
Lymphatic Malformations ◽  
Minimum Period ◽  
Sclerosing Agents ◽  
Group I ◽  
Sodium Tetradecyl Sulphate ◽  
Head Neck

The purpose of this study is to compare between the efficacy of Bleomycin and Sodium tetra decyl sulphate as intralesional sclerotherapy for lymphangioma. Materials and methods- This prospective study was done between Jan 2018 to Jan 2020. Total of 30 patients with lymphatic malformations at head neck, axilla, chest wall and lower limb were included. Group I was given intralesional injection of bleomycin and Group II was injected with STS. All the cases were evaluated for a minimum period of one and a maximum of 2 years. Result Efficacy of bleomycin was found to be superior to STS, when used as intralesional sclerotherapic agent. Most of the vascular lesions of group I resolved after first dose giving excellent response in 60% as compared to 40% in STS group. Conclusion Intralesional bleomycin and sodium tetradecyl sulphate are safe and effective sclerosing agents in lymphangiomas of children, but bleomycin is more effective in reducing the size of the lesions.

Lymphatic complications following an operation on varicose veins by patients with advanced venous insufficience

Phlebologie ◽  
2008 ◽  
Vol 37 (05) ◽  
pp. 253-258 ◽  
Author(s):  
N. König ◽  
Z. T. Miszczak ◽  
H. J. Stark ◽  
P.-M. Baier
Keyword(s):  
Prospective Study ◽  
Varicose Vein ◽  
Varicose Veins ◽  
Varicose Vein Surgery ◽  
Study Results ◽  
Lymphatic Complications ◽  
A Prospective Study

SummaryLymphatic complications are minor complications after varicose vein surgery. The frequency of lymphatic complications following an operation on varicose veins is very rarely discussed in literature. Patients, method: We investigated their frequency in a prospective study. Results: Between January 2004 and December 2005 in the cases of 3565 varicose vein operations we found 345 or 9.7% lymphatic complications, i.d. 123 cysts (3.4%), 24 fistulas (0.7%), 7 lymphorrhoe (0.2%) and 5 lymphoedema (0.14%). Conclusion: Lymphoedema is the only longlasting complication of the varicose vein surgery.

The Clinical and Histological Effects of Ethanolamine in Varicose Veins

1998 ◽  
Vol 13 (1) ◽  
pp. 29-30 ◽  
Author(s):  
J. G. Mosley ◽  
I. Gupta
Keyword(s):  
Prospective Study ◽  
Normal Saline ◽  
Varicose Veins ◽  
Varicose Vein Surgery ◽  
Histological Changes ◽  
Histological Damage ◽  
Complete Destruction ◽  
Sodium Tetradecyl Sulphate ◽  
A Prospective Study ◽  
Perforating Vein

Objective: To study the histological changes in varicosities after injection of 5% ethanolamine. Design: A prospective study in nine groups of six patients awaiting bilateral varicose vein surgery. Patients: Each patient had a below-knee incompetent perforating vein injected with either 0.5, 1.0 or 2.0 ml 5% ethanolamine. The contralateral varicosity received a similar volume of normal saline. Intervention: The patients wore elasticated stockings until admitted for operation at 2, 4 or 8 weeks after the injections. The injected varicosity was then dissected out. Main outcome measures: Each vein was reported on by a histologist who did not know which had received ethanolamine or saline. The histologist graded each vein according to the severity of change from 0 (no effect) to 5 (total obliteration of vein). Results: Ethanolamine at 0.5, 1.0 and 2.0 ml caused extensive histological damage to the varicosity. After 8 weeks most varicosities had been destroyed. Conclusion: Ethanolamine, unlike sodium tetradecyl sulphate, causes complete destruction of a varicosity. A dose of 0.5 ml is just as effective as 2.0 ml.

scholarly journals Efficacy of topical 5% fluorouracil (5%- FU) needling in vitiligo: فعالية الحقن الموضعي بالإبر الدقيقة لـ fluorouracil  5% في علاج البهاق

2021 ◽  
Vol 5 (4) ◽  
pp. 34-28
Author(s):  
Mai Abdulkhaliq Ibrahiem, Mohammed Adel Ismaiel Mai Abdulkhaliq Ibrahiem, Mohammed Adel Ismaiel
Keyword(s):  
Side Effects ◽  
Prospective Study ◽  
The Body ◽  
University Hospital ◽  
Safe Method ◽  
Study Results ◽  
One Year ◽  
A Prospective Study ◽  
Treatment Improvement

Objective: The aim of this study is to assess the efficacy of topical 5- fluorouracil (5%- FU) with micro needling in treating stable vitiligo. In addition to, assessment the side effects of the treatment. Patients and Methods: A Prospective study (Before& After) conducted for the period one year (April 2019- April2020)at Tishreen University Hospital in Lattakia- Syria, 31 patients with stable vitiligo who received treatment with micro needling and topical 5- fluorouracil (5%- FU) were included in this study. Results : The median age was 36 years, 67.70% of patients were female. Focal type was found in 61.3%, and most common sites of vitiligo involvement were hand and feet (33.7%), followed by trunk (24.8%)and extremities (24.8%). After 6 months of treatment, improvement was excellent in 63.4%, and very good in 23.8%. The lesions of neck and trunk were responded better to treatment than those in other parts of the body. Regarding of side effects, pain, erythema, and itching were reported in 100% followed by ulceration in (16.1%). Conclusion: Topical 5%- fluorouracil (5%- FU) with needling appears to be an effective and safe method in treating stable vitiligo. Except of pain, erythema, and itching after procedure, significant complications not occurred in most patients.

Sclerotherapy: a study comparing polidocanol in foam and liquid form

2010 ◽  
Vol 25 (1) ◽  
pp. 44-49 ◽  
Author(s):  
H Uncu
Keyword(s):  
Side Effects ◽  
Varicose Veins ◽  
Statistical Significance ◽  
Complete Disappearance ◽  
Women Patients ◽  
Foam Sclerotherapy ◽  
Liquid Form ◽  
Sclerosing Agents ◽  
Sclerosing Solutions ◽  
Significant Difference

Objectives Compression sclerotherapy has been satisfactorily used for half a century for the treatment of varicose veins of the lower extremities. The effect of sclerosing solutions is that of making endofibrosis and vascular damage via producing endothelial injury. Different sclerosing agents were used by applying many different sclerotherapy methods. In recent years, sclerosing foam has been introduced in sclerotherapy with the goal of increasing the efficacy in the treatment of varicose veins. It is still uncertain whether foam or liquid form is superior. The aim of this study is to determine the efficacy and safety of the sclerosant polidocanol – which is a well-known detergent-type sclerosing agent – in foam form compared with liquid form. Methods A total of 100 women patients with telengiectases and small varicose veins of less than 4 mm were included in this study. The patients were divided into two groups according to presenting dates. Fifty patients who presented first were classified as the first group. They were treated with Tessari's foam sclerotherapy method. The second fifty patients who presented later were placed in the second group. They were treated with the liquid form of polidocanol. Extremity veins that did not have insufficiency at the saphenofemoral junction were divided into three groups as <1 mm, 1–2 mm and >2 but <4 mm, and the veins were treated with 0.25%, 0.5% or 1% of polidocanol, respectively. Clinical improvement, patients' complaints and side-effects were determined after treatment. Results Complete disappearance was determined in 84% of patients in the foam form group and in 72% in the liquid form group. Although polidocanol in foam form's success rate was higher than the liquid form of polidocanol to clear the vessels, this result did not reach statistical significance ( P = 0.148). There was no significant difference also in the side effects between each group. Conclusion Compression sclerotherapy is an effective and useful method for treating small varicose veins and telengiectases. Both polidocanol foam and polidocanol liquid forms are effective and safe sclerosing agents. The rates of side-effects were similar for both sclerotherapy methods. Although efficacy to clear the small varicose veins and telengiectases with foam polidocanol seems to be more successful than with liquid polidocanol, it is early to declare the superiority of the foam sclerotherapy method.

EVALUATION OF THE EFECTS OF ELECTRONIC ACUPUNCTURE COMBINED WITH “TAM TY THANG” REMEDY IN THE TREATMENT OF RHEUMATOID ARTHRITIS BY WIND-COLD-DAMP

2017 ◽  
pp. 122-127
Author(s):  
Thi Luu Nguyen ◽  
Thi Tan Nguyen
Keyword(s):  
Rheumatoid Arthritis ◽  
Side Effects ◽  
Prospective Study ◽  
Key Words Rheumatoid Arthritis ◽  
Good Effect ◽  
Good Level ◽  
Relieve Pain ◽  
Level Of Activity ◽  
Before And After ◽  
The Moment

Objectives: To assess the effect of electronic acupuncture combined with “Tam ty thang” remedy in the treatment of rheumatoid arthritis by wind-cold-damp. Materials and methods: prospective study, comparing before and after treatment, including 43 patients who were diagnosed with rheumatoid arthritis by wind-cold-damp according to traditional medicine. Results: good level occupied 69,8%, and fair good level occupied 30,2%.The improved motor function accounted for 95.3%, to relieve pain up to 95,3%, reducing inflammation of VSS in 1 hour at the moment No 31,65, N28 17,88. The improvement in the level of activity of the hand reached 48,8% for good level. Conclusions: The method of electronic acupuncture combined with “Tam ty thang” remedy have a good effect in the treatment of rheumatoid arthritis by wind-cold-damp and it didn’t cause significantly side effects in clinic. Key words: rheumatoid arthritis, electronic acupuncture, “Tam ty thang” remedy

scholarly journals FRI0048 Side effects of methotrexate in therapy for rheumatoid arthritis ? five years prospective study

2001 ◽  
Author(s):  
SK Stojanovic ◽  
AM Stankovic ◽  
JM Nedovic ◽  
BN Stamenkovic ◽  
AN Dimic
Keyword(s):  
Rheumatoid Arthritis ◽  
Side Effects ◽  
Prospective Study
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