Anorectal pathology amongst HIV infected patients attending the Douala General Hospital: a cross-sectional study

2016 ◽  
Vol 28 (4) ◽  
pp. 389-396 ◽  
Author(s):  
Henry Namme Luma ◽  
Servais Albert Fiacre Bagnaka Eloumou ◽  
Ellis Atemlefeh Fualefeh-Morfaw ◽  
Agnes Malongue ◽  
Elvis Temfack ◽  
...  
Keyword(s):  
Logistic Regression ◽  
General Hospital ◽  
Laboratory Data ◽  
Study Participant ◽  
Cross Sectional Study ◽  
Interquartile Range ◽  
People Living With Hiv ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated

While gastrointestinal disease is common among HIV infected individuals, the prevalence and distribution of ano-rectal pathology has not been well studied in our setting. The objective of this study therefore was to determine the prevalence and determinants of ano-rectal pathology in HIV infected patients attending the Douala General Hospital HIV treatment centre. A hospital-based cross-sectional study was undertaken. We collected socio-demographic, clinical and laboratory data using a structured questionnaire and patients’ files. Each study participant had a full physical and ano-rectal examination. We further studied factors associated with having at least one ano-rectal lesion by logistic regression reporting odds ratios (ORs) and their 95% confidence intervals (CI). We included 390 HIV infected patients. The mean age was 41 (SD: 8) years and 48% were men. Median duration since HIV diagnosis was 3 (interquartile range: 2–5) years and median CD4 cell count was 411 (interquartile range: 234–601) cells/mm3. Prevalence of ano-rectal pathology was 22.8% (95% CI: 18.7–27.3). Hemorrhoids and proctitis were most common lesions found; each in 10% of patients. From multivariate logistic regression, factors associated with ano-rectal pathology were CD4 < 350 cells/ml (OR: 2.1, 95% CI: 1.1–4.2), not on highly active antiretroviral therapy (OR: 2.2, 95% CI: 1.1–4.6), inpatient (OR: 2.3, 95% CI: 1.2–4.3), ano-rectal intercourse (OR: 5.0, 95% CI: 1.7–15.1), and more than one sexual partner (OR: 2.4, 95% CI: 1.3–4.2). Ano-rectal pathology is common amongst HIV infected patients. Care givers should actively investigate and treat them as this will improve the quality of life of people living with HIV/AIDS.

scholarly journals Predictors of HIV/AIDS comprehensive knowledge and acceptance attitude towards people living with HIV/AIDS among unmarried young females in Uganda: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tesfaldet Mekonnen Estifanos ◽  
Chen Hui ◽  
Afewerki Weldezgi Tesfai ◽  
Mekonnen Estifanos Teklu ◽  
Matiwos Araya Ghebrehiwet ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Analysis ◽  
Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
People Living With Hiv ◽  
Sectional Study ◽  
Cross Sectional ◽  
Young Females ◽  
Comprehensive Knowledge ◽  
Hiv Aids

Abstract Background Youth in general and young females, in particular, remain at the center of HIV/AIDS epidemic. To avoid and prevent HIV infection, comprehensive knowledge as well as correct understanding of transmission and prevention strategies are crucial. Thus, the aim of this study is to explore the predictors of comprehensive knowledge on HIV/AIDS and accepting attitude towards PLWHIV. Methods A cross-sectional study was conducted using data from the 2016 Uganda Demographic Health Survey. A two-stage probability sampling method was applied and data were collected using a standard questionnaire. Of the total 8674 women aged 15–49 years, 1971 eligible women aged 15–24 years were included in this analysis. Data analysis was done using SPSS version 23. A Chi-square test followed by logistic regression analysis was used to explore the relationship between specific explanatory variables and outcome variables. The results were reported using odds ratios with 95% confidence interval. P value less than 0.05 was considered as statistically significant. Results Overall, 99.3% of the unmarried women aged 15–24 years were aware of HIV/AIDS, but only 51.9% had comprehensive knowledge on HIV/AIDS. Around 70% of the respondents were aware that "using condoms every time when having sex" and "having only one faithful uninfected partner" can prevent HIV transmission. About 68% of the unmarried women rejected at least two common local misconceptions about HIV/AIDS. An alarmingly small (20.6%) proportion of the respondents had a positive acceptance attitude towards PLWHIV. All variables were significantly associated with having comprehensive knowledge on HIV/AIDS in the unadjusted logistic regression analysis. After adjustment, older age (20–24 years), being educated, wealthier, and ever been tested for HIV/AIDS became predictors of adequate comprehensive HIV/AIDS knowledge. Moreover, respondents with adequate comprehensive knowledge of HIV/AIDS were more likely (OR 1.64, 95% CI 1.30–2.08) to have a positive acceptance attitude towards PLWHIV than their counterparts. Conclusion Our study demonstrated a remarkably high level of awareness about HIV/AIDS among study participants, but the knowledge and positive acceptance attitude towards PLWHIV were not encouraging. Thus, endeavors to expand and strengthen educational campaigns on HIV/AIDS in communities, health facilities, and schools are highly recommended. Attention should particularly focus on young-aged and disadvantaged women with low educational level, poor socioeconomic status and those who have never been tested for HIV/AIDS.

scholarly journals Hematological Parameters and Hemozoin-Containing Leukocytes and Their Association with Disease Severity among Malaria Infected Children: A Cross-Sectional Study at Pawe General Hospital, Northwest Ethiopia

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Muluken Birhanu ◽  
Yaregal Asres ◽  
Wondimagegn Adissu ◽  
Tilahun Yemane ◽  
Endalew Zemene ◽  
...  
Keyword(s):  
General Hospital ◽  
Severe Malaria ◽  
Disease Severity ◽  
Hematological Parameters ◽  
Study Participant ◽  
Cross Sectional Study ◽  
Hematological Parameter ◽  
Sectional Study ◽  
Cross Sectional ◽  
Study Participants

Hematological parameter changes are the most common complications in malaria. We aimed to determine the hematological parameters and hemozoin-containing leukocytes and their association with disease severity in malaria infected children aged between 1 and 15 years. A facility-based cross-sectional study was conducted at Pawe General Hospital from July 31 to December 30, 2014. Demographic and clinical data were collected using structured questionnaire. Blood specimen was collected from each study participant for hematological investigations. Data were analyzed using SPSS version 20. The overall prevalence of anemia was 40.3%, most of which were mildly anemic. Leukocytosis was found in 15.4% of study participants. More than a fourth (27%) of the children had severe malaria. Hemozoin-containing monocytes and neutrophils were found in 80.1% and 58.9% of the study participants, respectively. Under-five years of age (AOR = 3.01, 95% CI: 1.83–7.39,P<0.001), leukocytosis (AOR = 3.20, 95% CI: 1.65–6.24,P=0.001), mean hemozoin-containing monocytes >5% (AOR = 6.26, 95% CI: 2.14–14.29,P<0.001), mean hemozoin-containing neutrophils >5% (AOR = 7.93, 95% CI: 3.09–16.86,P<0.001), and high density parasitemia (AOR = 1.90, 95% CI: 1.13–3.18,P=0.015) were associated with severe malaria. Hemozoin-containing leukocytes, leukocytosis, and other identified associated factors should be considered for proper management of children with severe malaria.

scholarly journals Internet Addiction and its Associated Factors Among Dilla University Undergraduate Students, Dilla, Ethiopia, 2019: A Cross-Sectional Study

2021 ◽  
Author(s):  
Nebiyu Mengistu ◽  
Desalegn Tarekegn ◽  
Wondwosen Molla ◽  
Seid Shumye
Keyword(s):  
Logistic Regression ◽  
University Students ◽  
Undergraduate Students ◽  
Internet Addiction ◽  
Associated Factors ◽  
Internet Use ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated

Abstract Background: Internet addiction is characterized by excessive or poorly controlled preoccupation, urges or behavior regarding computer use and internet access that lead to impairment or distress. Globally, it has been found that the occurrence rate of internet addiction among university students ranges from 0.8% to 47.7%. Despite, there are multiple challenges that related with internet addiction which remains under-recognized and largely ignored by stakeholders and also not well known especially in low income countries including Ethiopia. Therefore, this study was conducted aimed to assess the magnitude of the internet addiction and its associated factors among undergraduate students. Methods: Institutional based cross-sectional study was employed from May 1st to June 1st 2019. Multi-stage sampling technique was used to get a total of 846 undergraduate Students. Data was collected by using self-administered structured questionnaires of Young’s Internet Addiction Test. The collected data was coded and entered into EPIDATA 3.1 and analyzed by using SPSS version 22, Bivariate and multivariate logistic regression analysis was conducted to identify factors associated with internet addiction and statistically significant was considered at P-value <0.05. Results: A total of 846 study participants, giving a response rate were 761 (90%) and the prevalence of internet addiction was 19.4%. Multiple logistic regression model revealed that being male [AOR=1.69, 95% CI: (1.80, 6.41)], probable depression [AOR =3.61, 95% CI (2.40, 5.43)] and khat or caffeinated drinks [AOR=1.86, 95%CI: (1.21, 2.87)] were significantly associated with internet addiction.Conclusion: This study revealed that a high prevalence of internet addiction among Dilla university students and there were various factors associated with increased prevalence of problematic internet use. Therefore, students need to be educated about safe, valuable, and healthy practice of internet use and better to counsel on substance use and its consequences and also psychiatric evaluation (referring for mental health services) to overcome the anticipated increase in internet addiction

scholarly journals Factors associated with HIV-related stigma toward people living with HIV among nurses in Liangshan Yi Autonomous Prefecture, China: a cross-sectional study

2019 ◽  
Author(s):  
Yao Yin ◽  
Angela Chia-Chen Chen ◽  
Shaoping Wan ◽  
Hong Chen
Keyword(s):  
Online Survey ◽  
Cross Sectional Study ◽  
People Living With Hiv ◽  
Sectional Study ◽  
Hiv Knowledge ◽  
Cross Sectional ◽  
Factors Associated ◽  
Related Stigma ◽  
Tertiary Hospitals ◽  
Living With Hiv

Abstract Background The Liangshan Yi Autonomous Prefecture has one of the most serious human immunodeficiency virus (HIV) epidemics in China. Evidence shows HIV-related stigma toward people living with HIV (PLWH) among nurses impedes HIV prevention and treatment. However, only limited research about HIV-related stigma toward PLWH from the perspective of nurses in Liangshan has been conducted. This cross-sectional study aimed to assess HIV-related stigma toward PLWH among nurses and determine factors associated with it in Liangshan, China. Methods Using a stratified, random cluster sampling method, registered nurses (N=1,248; primary hospitals=102, secondary hospitals=592, tertiary hospitals=554) were recruited 10 hospitals in Liangshan. All participants completed an anonymous online survey measuring sociodemographic characteristics, HIV-related stigma and HIV knowledge. We used multiple stepwise regression analysis to examine factors associated with HIV-related stigma toward PLWH among these nurses. Results The mean score of HIV-related stigma among nurses was 50.7 (SD = 8.3; range 25-78). Nurses who were more experienced, had higher levels of education, and were working in tertiary hospitals reported higher level of HIV-related stigma. Those who had better HIV knowledge, reported a willingness to receive HIV-related training, were working in areas that had a high prevalence of HIV, had prior experience working in acquired immune deficiency syndrome (AIDS) specialized hospitals, and worked in hospitals that had policies to protect PLWH showed a lower level of HIV-related stigma toward PLWH. Conclusions Findings suggested that providing culturally congruent education and training about HIV and care, and having hospitals that promoted policies protecting PLWH, may reduce HIV-related stigma toward PLWH among nurses in China.

scholarly journals Random forest algorithm to identify factors associated with sports-related dental injuries in 6 to 13-year-old athlete children in Hamadan, Iran-2018 -a cross-sectional study

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Maryam Farhadian ◽  
Sima Torkaman ◽  
Farzad Mojarad
Keyword(s):  
Logistic Regression ◽  
Random Forest ◽  
Cross Sectional Study ◽  
Machine Learning Algorithms ◽  
Sectional Study ◽  
Sports Activity ◽  
Cross Sectional ◽  
Dental Injury ◽  
Factors Associated ◽  
Dental Injuries

Abstract Background Traumatic dental injuries are one of the most important problems with major physical, aesthetic, psychological, social, functional and therapeutic problems that adversely affect the quality of life of children and adolescents. Recently the development of methods based on machine learning algorithms has provided researchers with more powerful tools to more accurate prediction in different domains and evaluate the factors affecting different phenomena more reliably than traditional regression models. This study tries to investigate the performance of random forest (RF) in identifying factors associated with sports-related dental injuries. Also, the accuracy of the RF model for predicting sports-related dental injuries was compared with logistic regression model as traditional competitor. Methods This cross-sectional study was applied to 356 athlete children aged 6 to 13-year-old in Hamadan, Iran. Random forest and logistic regression constructed by using sports-related dental injuries as response variables and age, sex, parent’s education, child’s birth order, type of sports activity, duration of sports activity, awareness regarding the mouthguard, mouthguard use as input. A self-reported questionnaire was used to obtain information. Results Fifty-five (15.4%) subjects had experienced a sports-related dental injury. The mean age of children with sports injuries was significantly higher than children without the experience of injury (p = 0.006). The prevalence of injury was significantly higher in boys (p = 0.008). Children with illiterate mothers are more likely to be injured than children with educated mothers (p = 0.045). Awareness of mouthguard and its use during exercise has a significant effect on reducing the prevalence of injury among users (p < 0.001). Random forest model has a higher prediction accuracy (89.3%) for predicting sports-related dental injuries compared to the logistic regression (84.2%). The results of the relative importance of variables, based on RF showed, mouthguard use, and mouthguard awareness has more contributed importance in dental sport-related injuries’ prediction. Subsequently, the importance of sex and age is in the next position. Conclusions Using predictive models such as RF challenges existing inaccurate predictions due to high complexity and interactions between variables would be minimized. This helps to achieve more accurate identification of factors in sport-related dental injury among the general population of children.

scholarly journals Self-management and its associated factors among people living with diabetes in Blantyre, Malawi: a cross-sectional study

2021 ◽  
Vol 2 ◽  
pp. 161
Author(s):  
Chimwemwe Kwanjo Banda ◽  
Belinda T. Gombachika ◽  
Moffat J. Nyirenda ◽  
Adamson Sinjani Muula
Keyword(s):  
Logistic Regression ◽  
Self Efficacy ◽  
Social Cognitive ◽  
Management Practices ◽  
Cross Sectional Study ◽  
The Self ◽  
Self Management ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated

Background: Self-management is key to the control of glycaemia and prevention of complications in people with diabetes. Many people with diabetes in Malawi have poorly controlled glucose and they experience diabetes-related complications. This study aimed to assess diabetes self-management behaviours and to identify factors associated with it among people with diabetes at Queen Elizabeth Central Hospital, Blantyre, Malawi. Methods: This cross-sectional study recruited 510 adults attending a diabetes clinic at a teaching referral hospital in southern Malawi. The social cognitive theory was applied to identify factors associated with following all recommended self-management behaviours. Data on participants’ demographics, clinical history, diabetes knowledge, self-efficacy, outcome expectations, social support, environmental barriers and diabetes self-management were collected. Univariate and multivariate logistic regression analyses were conducted to identify factors associated with following all self-management behaviours. Results: The mean age of participants was 53.6 (SD 13.3) years. The majority (82%) were females. Self-reported medication adherence within the last seven days was 88.6%; 77% reported being physically active for at least 30 minutes on more than three days in the previous seven days; 69% reported checking their feet every day and inspecting inside their shoes; 58% reported following a healthy diet regularly. Only 33% reported following all the self-management behaviours regularly.  Multiple logistic regression analysis showed that self-efficacy was the only social cognitive factor associated with following all the self-management practices (p < 0.001). Conclusions: Participants in our study were not consistently achieving all self-management practices with dietary practices being the least adhered to behaviour by many. To improve self-management practices of people with diabetes, current health education programs should not only aim at improving diabetes related knowledge but also self-efficacy. Adopting interventions that promote self-efficacy in diabetes patients such as exposure to role models, peer education, providing positive feedback, and counselling is recommended.

scholarly journals Factors associated with overactive bladder syndrome in the elderly community: a cross-sectional study

2017 ◽  
Vol 20 (4) ◽  
pp. 474-483
Author(s):  
Albênica Paulino dos Santos Bontempo ◽  
Aline Teixeira Alves ◽  
Gabriela de Sousa Martins ◽  
Raquel Henriques Jácomo ◽  
Danieli Coeli Malschik ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Overactive Bladder ◽  
Cross Sectional Study ◽  
Sexual Life ◽  
Case Group ◽  
Overactive Bladder Syndrome ◽  
Depression And Anxiety ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated

Abstract Objective: to identify risk factors related to overactive bladder syndrome. Method: a cross-sectional study was performed with elderly women (>60 years) from the community of Ceilândia, in the Distrito Federal, Brazil, with or without symptoms of OBS, who were evaluated through interviews and questionnaires. The clinical and sociodemographic variables analyzed were: age; body mass index (BMI); parity, schooling, previous abdominal and urogynecologic surgeries, physical activity, smoking, constipation, systemic arterial hypertension (SAH), diabetes mellitus; depression and anxiety. The questionnaires applied were the Overactive Bladder Awareness Tool (OAB-V8), the Geriatric Depression Scale and the Beck Anxiety Scale. Data were analyzed descriptively. Binary logistic regression was used to evaluate the significant associations between the independent variables and the outcome of interest. Risk ratios were calculated for each independent variable with 95% confidence intervals. Result: A total of 372 volunteers were recruited, 292 of whom were eligible. Of these, 172 were allocated to the case group (58.9%) and 120 (41.1%) were control subjects. The two groups were homogeneous between one another. There was a high prevalence of OBS in the study population and significant differences for the variables presence of SAH, abdominal surgery and pelvic surgery, with the case group presenting a higher frequency of these events. In multivariate analysis, it was observed that an active sexual life reduces the chance of having OBS by 70.8%, while urogynecologic surgeries increase this risk 3.098 times. Conclusion: In univariate logistic regression analysis, BMI, SAH, a previous history of abdominal and urogynecologic surgery, number of abortions and the presence of symptoms of depression and anxiety, were found to be factors associated with OBS.

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