scholarly journals Commentary on the use of the reproduction number R during the COVID-19 pandemic

2021 ◽  
pp. 096228022110370
Author(s):  
Carolin Vegvari ◽  
Sam Abbott ◽  
Frank Ball ◽  
Ellen Brooks-Pollock ◽  
Robert Challen ◽  
...  
Keyword(s):  
Statistical Methods ◽  
Reproduction Number ◽  
Infected Individual ◽  
The State ◽  
Precise Definition ◽  
Basic Formula ◽  
Secondary Infections ◽  
Number Formula ◽  
Definition Of ◽  
Future Management

Since the beginning of the COVID-19 pandemic, the reproduction number [Formula: see text] has become a popular epidemiological metric used to communicate the state of the epidemic. At its most basic, [Formula: see text] is defined as the average number of secondary infections caused by one primary infected individual. [Formula: see text] seems convenient, because the epidemic is expanding if [Formula: see text] and contracting if [Formula: see text]. The magnitude of [Formula: see text] indicates by how much transmission needs to be reduced to control the epidemic. Using [Formula: see text] in a naïve way can cause new problems. The reasons for this are threefold: (1) There is not just one definition of [Formula: see text] but many, and the precise definition of [Formula: see text] affects both its estimated value and how it should be interpreted. (2) Even with a particular clearly defined [Formula: see text], there may be different statistical methods used to estimate its value, and the choice of method will affect the estimate. (3) The availability and type of data used to estimate [Formula: see text] vary, and it is not always clear what data should be included in the estimation. In this review, we discuss when [Formula: see text] is useful, when it may be of use but needs to be interpreted with care, and when it may be an inappropriate indicator of the progress of the epidemic. We also argue that careful definition of [Formula: see text], and the data and methods used to estimate it, can make [Formula: see text] a more useful metric for future management of the epidemic.

Evolution of SARS-CoV-2 in the state of Alagoas-Brazil via an adaptive SIR model

2020 ◽  
pp. 2150040
Author(s):  
I. F. F. Dos Santos ◽  
G. M. A. Almeida ◽  
F. A. B. F. De Moura
Keyword(s):  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Sir Model ◽  
The State ◽  
Epidemic Dynamics ◽  
Historical Series ◽  
Input Parameters ◽  
Number Formula ◽  
Near Future ◽  
The Basic Reproduction Number

We investigate the spreading of SARS-CoV-2 in the state of Alagoas, northeast of Brazil, via an adaptive susceptible-infected-removed (SIR) model featuring dynamic recuperation and propagation rates. Input parameters are defined based on data made available by Alagoas Secretary of Health from April 19, 2020 on. We provide with the evolution of the basic reproduction number [Formula: see text] and reproduce the historical series of the number of confirmed cases with less than [Formula: see text] error. We offer predictions, from November 16 forward, over the epidemic situation in the near future and show that it will keep decelerating. Furthermore, the same model can be used to study the epidemic dynamics in other countries with great easiness and accuracy.

Serbian Textbooks: Toward Greater Serbia or Yugoslavia?

Slavic Review ◽  
1983 ◽  
Vol 42 (4) ◽  
pp. 601-619 ◽  
Author(s):  
Charles Jelavich
Keyword(s):  
Nineteenth Century ◽  
Trade Policy ◽  
Direct Product ◽  
The State ◽  
Precise Definition ◽  
Political Organization ◽  
Local Autonomy ◽  
Basic Premise ◽  
Definition Of

As is well known, the Kingdom of the Serbs, Croats, and Slovenes, which was founded on December 1,1918, did not achieve the success envisaged for it. It is generally assumed that the state was the direct product of Yugoslavism, a Croatian concept formulated in the nineteenth century, which found adherents among the Serbs and Slovenes. Although there is no consensus among scholars concerning the precise definition of Yugoslavism, in its basic terms the concept called for the union of the Serbs, Croats, and Slovenes in one state. The proponents of Yugoslavism argued that as long as the three nations remained separate they were subject to domination by their stronger neighbors, whereas united they would be in a better position to determine their own future. These proponents never agreed on the exact political organization of the union, whether it should be a centralized or federalized state, but they assumed that the kingdom would have one army and a single foreign and trade policy, and that each nation would retain considerable local autonomy, for example, in education, religious affairs, and police jurisdiction. Yet the ultimate success of Yugoslavism was dependent on the acceptance by Serbs, Croats, and Slovenes of the basic premise that they were in essence one people, and that eventually they would no longer give primacy to their Serbianism, Croatianism, and Slovenianism but would offer their undivided loyalty to the larger Yugoslav concept.

scholarly journals Il recupero del sé attraverso l'autobiografia

2005 ◽  
Author(s):  
Leonardo Trisciuzzi ◽  
Barbara Sandrucci ◽  
Tamara Zappaterra
Keyword(s):  
Mental Activity ◽  
The State ◽  
Precise Definition ◽  
The Other ◽  
Definition Of ◽  
Over Time

The request for a precise definition of memory would put any serious academic into difficulty. To provide a synthetic response, we could define memory as a marvellous mechanism, a means for taking us back in time. Memory is, therefore, a mental activity which connects us over time and gives a meaning to existence. Telling one's story, one's autobiography, signifies primarily taking stock of the state of one's own identity; it signifies communication, communicating who we are to ourselves and others. It means transforming the interior monologue into dialogue with the other; it means scanning and modulating our emotions through the representation of the events of our lives.

scholarly journals Derivation of the effective reproduction number ℛ for COVID-19 in relation to mobility restrictions and confinement

2020 ◽  
Author(s):  
Alex Arenas ◽  
Wesley Cota ◽  
Jesús Gómez-Gardeñes ◽  
Sergio Gómez ◽  
Clara Granell ◽  
...  
Keyword(s):  
Health System ◽  
Health Systems ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Infected Individual ◽  
Analytical Expression ◽  
Secondary Infections ◽  
Essential Services ◽  
Asymptomatic Individuals ◽  
Key Parameter

The spread of COVID-19 is posing an unprecedented threat to health systems worldwide1. The fast propagation of the disease combined with the existence of covert contagions by asymptomatic individuals make the controlling of this disease particularly challenging. The key parameter to track the progression of the epidemics is the effective reproduction number ℛ, defined as the number of secondary infections generated by an infected individual2. The suppression of the epidemics is directly related to this value, and is attained when ℛ < 1. Here, we find an analytical expression for ℛ as a function of mobility restrictions and confinement measures, using an epidemic model tailored for COVID-19. This expression for ℛ is an extremely useful tool to design containment policies that are able to suppress the epidemics. We applied our epidemic model for the case of Spain, successfully forecasting both the observed incidence in each region and the overload of the health system. The expression for ℛ allowed us to determine the precise reduction of mobility κ0 needed to bend the curve of epidemic incidence, which turned out to be κ0 ∼ 0.7. This value, for the case of Spain, translates to a total lockdown with the exception of the mobility associated to essential services, a policy that was finally enforced on March 28.

Initial Polymerization Sites Indicated During Mitochondrial Oxidation of Diaminobenzidine after Toluene Treatment

1977 ◽  
Vol 35 ◽  
pp. 408-409
Author(s):  
W. A. Shannon ◽  
M. A. Matlib
Keyword(s):  
Membrane Permeability ◽  
Cytochrome Oxidase ◽  
Rat Liver ◽  
Precise Definition ◽  
Cytochemical Localization ◽  
Oxidative Reaction ◽  
Mitochondrial Oxidation ◽  
Definition Of ◽  
Exogenous Substrates

Numerous studies have dealt with the cytochemical localization of cytochrome oxidase via cytochrome c. More recent studies have dealt with indicating initial foci of this reaction by altering incubation pH (1) or postosmication procedure (2,3). The following study is an attempt to locate such foci by altering membrane permeability. It is thought that such alterations within the limits of maintaining morphological integrity of the membranes will ease the entry of exogenous substrates resulting in a much quicker oxidation and subsequently a more precise definition of the oxidative reaction.The diaminobenzidine (DAB) method of Seligman et al. (4) was used. Minced pieces of rat liver were incubated for 1 hr following toluene treatment (5,6). Experimental variations consisted of incubating fixed or unfixed tissues treated with toluene and unfixed tissues treated with toluene and subsequently fixed.

PERTANGGUNGJAWABAN KERUGIAN NEGARA DALAM PENGELOLAAN KEUANGAN DAERAH

EDUKASI ◽  
2018 ◽  
Vol 16 (1) ◽  
Author(s):  
Hendra Karianga
Keyword(s):  
Financial Management ◽  
Criminal Liability ◽  
The State ◽  
Legal Proceedings ◽  
Regional Finance ◽  
Regional Budget ◽  
State Finance ◽  
Budget Policy ◽  
Definition Of ◽  
The Impact

Sources of revenue and expenditure of APBD (regional budget) can be allocated to finance the compulsory affairs and optional affairs in the form of programs and activities related to the improvement of public services, job creation, poverty alleviation, improvement of environmental quality, and regional economic growth. The implications of these policies is the need for funds to finance the implementation of the functions, that have become regional authority, is also increasing. In practice, regional financial management still poses a complicated issue because the regional head are reluctant to release pro-people regional budget policy, even implication of regional autonomy is likely to give birth to little kings in region causing losses to state finance and most end up in legal proceedings. This paper discusses the loss of state finance and forms of liability for losses to the state finance. The result of the study can be concluded firstly,  there are still many differences in giving meaning and definition of the loss of state finace and no standard definition of state losses, can cause difficulties. The difficulty there is in an effort to determine the amount of the state finance losses. The calculation of state/regions losses that occur today is simply assessing the suitability of the size of the budget and expenditure without considering profits earned by the community and the impact of the use of budget to the community. Secondly, the liability for losses to the state finance is the fulfillment of the consequences for a person to give or to do something in the regional financial management by giving birth to three forms of liability, namely the Criminal liability, Civil liability, and Administrative liability.Keywords: state finance losses, liability, regional finance.

Implications

2017 ◽  
Author(s):  
Karl Widerquist ◽  
Grant S. McCall
Keyword(s):  
Property Rights ◽  
The State ◽  
Natural Property ◽  
Government Failure ◽  
State Of Nature ◽  
Best Response ◽  
Lockean Proviso ◽  
Definition Of ◽  
Taking Action ◽  
Disadvantaged People

Earlier chapters of this book found that the Hobbesian hypothesis is false; the Lockean proviso is unfulfilled; contemporary states and property rights systems fail to meet the standard that social contract and natural property rights theories require for their justification. This chapter assesses the implications of those findings for the two theories. Section 1 argues that, whether contractarians accept or reject these findings, they need to clarify their argument to remove equivocation. Section 2 invites efforts to refute this book’s empirical findings. Section 3 discusses a response open only to property rights theorists: concede this book’s empirical findings and blame government failure. Section 4 considers the argument that this book misidentifies the state of nature. Section 5 considers a “bracketing strategy,” which admits that observed stateless societies fit the definition of the state of nature, but argues that they are not the relevant forms of statelessness today. Section 6 discusses the implications of accepting both the truth and relevance of the book’s findings, concluding that the best response is to fulfil the Lockean proviso by taking action to improve the lives of disadvantaged people.

Ground of mechanism of pay in a budget for the pipelinetransporting of hydrocarbon commodities

2019 ◽  
pp. 141-152
Author(s):  
Adam Bodіuk
Keyword(s):  
The State ◽  
Practical Significance ◽  
State Budget ◽  
Economic Interests ◽  
State Recognition ◽  
Main Pipelines ◽  
Business Entities ◽  
Combination Of Methods ◽  
Definition Of ◽  
Hydrocarbon Transport

The subject of the study is the mechanism for determining the fiscal fee forthe main transportation of hydrocarbon goods as a resource concept. The purposeof this article is to justify the nature and prospects of using, instead of currentrent, hydrocarbon fiscal-main income as a fiscal payment, which is brought intothe state budget by operators of the main hydrocarbon-transport system as business entities for their transportation of hydrocarbons and products of their processing through main pipelines appropriate to the economic requirements. Theresearch methodology is determined by a combination of methods: a) cognition:legal analysis (study of the regulatory framework for the use of rent); b) justification: abstract logical analysis (definition of the concepts of hydrocarbon fiscalmain income); c) generalization (substantiation of conclusions and proposals).Results of work. In the process of analyzing the regulatory legal acts that regulate the use of current annuity as payment to the budget for the main transportation of hydrocarbons, it was established that it is not a tax in the interpretationof PKU, since the essence does not meet the official definition of tax, does notmeet the accepted definition of the concept of rent. The accepted nature andmechanism of paying rent for the transportation of hydrogen resources and associated revenues of the state and users of the main hydrogen transport systemand the unpromising nature of its use as a fiscal payment are analyzed. Conclusions.It is proposed that the state pay for the territorial pumping of hydrocarbon resources according to our triple principle as hydrocarbon fiscal-main income, whichcorresponds to its essence, and accordingly change the mechanism for calculatingand depositing funds to treasury accounts. Since the funds come to the revenueside of the state budget, that is, inherently belong to state revenue. The creationof such a mechanism needs certain studies, justifications and government decisions. The same applies to land use, since the quality indicators of soils, wherethe laid pipelines are territorially different. In addition, there is a process ofchanging land for its intended purpose, for the property. The fee for movinghydrocarbon resources should be calculated depending on the type of transport,including pipelines, for a set of indicators: quantity and quality of goods, time,main tariffs and distance of its movement. The amount may be adjusted usingfactors officially established by the CMU. Since the pipelines are located in territorial lands, part of this fee should be transferred to the territorial local budgets.Theoretically, the economic use of trunk pipelines should be considered as a typeof economic environmental management. Therefore, this type of government revenue should be determined by a set of indicators, as well as taking into account the economic interests of business entities authorized by the CMU. Thus, theimplementation of our proposed fiscal payment is relevant, has scientific noveltyand promising practical significance, therefore, for state recognition it is proposedto include it in the Tax Code of Ukraine.

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