Pancreatic cancer

2019 ◽  
Vol 12 (9) ◽  
pp. 492-496
Author(s):  
Matthew C M Mortimer ◽  
Jessica L Ovens

Pancreatic cancer is the eleventh most common cancer in the UK, yet it is the fifth most common cause of cancer death. In the UK, the age-standardised incidence has risen by 11% over the last decade. The symptoms are often vague, and as a result, it rarely presents at an early stage. Prognosis is determined by stage at presentation, therefore prompt recognition and referral of suspicious symptoms is vital. Survival rates remain poor, with just a 3% rate of 5-year survival. GPs therefore have an important role in both the early recognition and palliative care of patients with pancreatic cancer.

2012 ◽  
Vol 5 (6) ◽  
pp. 345-350 ◽  
Author(s):  
Ruchit Sood ◽  
Karen Neoh ◽  
Ranjeeta Bakashi ◽  
Katherine Argyle ◽  
Rodger Toner

Pancreatic cancer is the tenth most common cancer in the UK and the fifth leading cause of cancer death (UK). According to the Office for National Statistics, there were 8085 new cases and 7781 deaths in 2008, highlighting its extremely poor prognosis. The average-size GP practice is likely to see at least one case of pancreatic cancer per year. Currently, only 13% of cases are diagnosed through the 2 week wait referral pathway, with 47% presenting as hospital emergencies. Delay in diagnosis can be multifactorial. Early symptoms tend to be non-specific and signs and symptoms such as painless jaundice and weight loss do not present until late stages. Early recognition by the GP is crucial as surgical resection offers the best chance of survival. GPs also play a crucial role in providing palliative care in patients who have unresectable disease.


2017 ◽  
Vol 27 (7-8) ◽  
pp. 158-162 ◽  
Author(s):  
K Gedge

Pancreatic cancer is the fifth most common cause of cancer death in the UK. This disease often remains undiagnosed until it is at a late stage, resulting in the majority of tumours being unsuitable for surgical resection. When a diagnosis of pancreatic cancer is confirmed, early input from the multi-disciplinary team (MDT) is vital. Due to the poor prognosis, the screening and treatment of pancreatic cancer remains a considerable challenge for medicine in the 21st century.


2019 ◽  
pp. 3-5
Author(s):  
Nelya Melnitchouk ◽  
Galyna Shabat

The incidence of colorectal cancer (CRC) is increasing worldwide and it is the second most common cause of cancer death. There is a lot of investigations and improvement to rise quality of early diagnosis, successful treatment and effective preventions of colorectal cancer. Nowadays available few guidelines of international and national organizations what support effectiveness of screening programs. Colorectal cancer screening is effective way to decrease incidence and mortality with strong evidence confirmed by a lot of investigations of different scientific groups. Currently, Ukraine doesn’t have an established colorectal cancer program, what need to be changed as soon as possible. A lot of patients in Ukraine wait at home till the beginning of clinical symptoms, what often is the representation of later stage of diseases; and of course treatment of patients with later stage of diseases need more costs for treatment and show worst results of morbidity and mortality rate compare with patients treated at the early stage of diseases. We created a simulation Markov model and demonstrated that the implementation of the national screening program for colorectal cancer in Ukraine will be cost saving and will decrease the mortality from colorectal cancer significantly.


Introduction 232 Respiratory symptoms related to lung cancer 232 Primarily non-respiratory symptoms related to lung cancer 233 Attendance as a complication of therapy 233 Presentation with unrelated illness 234 Assessment and evaluation 234 Management 234 Lung cancer is the most common cause of cancer death in the UK and therefore is likely to present to the acute physician at some time. This chapter deals briefly with lung cancer itself; for more detailed information see OHRM, Chapter 18. Patients with a known diagnosis of lung cancer may present acutely with symptoms due to the primary problem of the lung cancer itself (which may or may not be with primarily respiratory symptoms), complications of treatment, or a respiratory presentation due to coexisting respiratory disease....


2009 ◽  
Vol 7 (4) ◽  
pp. 423-427 ◽  
Author(s):  
Kwang-Yu Chang ◽  
Jang-Yang Chang ◽  
Yun Yen

Primary liver cancer is the sixth most common cancer and third most common cause of cancer death worldwide. Cholangiocarcinoma is the second most common primary liver tumor after hepatocellular carcinoma. Because the incidence of intrahepatic cholangiocarcinoma is rising in most areas worldwide, identification of the main causes of this problem is urgently needed. Despite well-known risk factors in the development of intrahepatic cholangiocarcinoma, recent reports focus on chronic hepatitis B and C viral infections because an increasing number of studies have observed an association. The relationship, however, is still not conclusive because of the diversity in clinical reports and the lack of in vitro evidences. This issue should be emphasized and further investigation is required for clarification.


Author(s):  
Natalie Cheyne ◽  
David Nichols ◽  
Amit Kumar

As cancer treatment improves and survival rates continue to increase, clinicians are seeing increasing numbers of patients with metastatic bone disease (MBD). This term describes cancer that has originated in another organ and subsequently spread to the bone. It is a condition that can severely impact the quality of life for an individual and the treatment is often not curative. This article aims to cover the management of MBD, from early recognition to secondary care interventions. The care of individuals with MBD is evolving in the UK, with the development of specialist regional referral pathways to facilitate prompt and timely management.


Open Biology ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. 170070 ◽  
Author(s):  
Sean Blandin Knight ◽  
Phil A. Crosbie ◽  
Haval Balata ◽  
Jakub Chudziak ◽  
Tracy Hussell ◽  
...  

Lung cancer is the leading cause of cancer-related death in the world. It is broadly divided into small cell (SCLC, approx. 15% cases) and non-small cell lung cancer (NSCLC, approx. 85% cases). The main histological subtypes of NSCLC are adenocarcinoma and squamous cell carcinoma, with the presence of specific DNA mutations allowing further molecular stratification. If identified at an early stage, surgical resection of NSCLC offers a favourable prognosis, with published case series reporting 5-year survival rates of up to 70% for small, localized tumours (stage I). However, most patients (approx. 75%) have advanced disease at the time of diagnosis (stage III/IV) and despite significant developments in the oncological management of late stage lung cancer over recent years, survival remains poor. In 2014, the UK Office for National Statistics reported that patients diagnosed with distant metastatic disease (stage IV) had a 1-year survival rate of just 15–19% compared with 81–85% for stage I.


Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1268
Author(s):  
Kazushi Numata

Liver cancer is the sixth most common cancer and the third most common cause of cancer death, based on Global Cancer Statistics 2020 [...]


Author(s):  
Michael Bryant

Lung cancer is the most common cause of cancer-related death in men, and the second most common one in women. The primary cause remains tobacco smoking, but there is an ongoing association with air pollution and specific carcinogens including radon, asbestos and coal fumes. The outcomes remain poor with fewer than one-in-five patients surviving 5 years after diagnosis. Lung cancer presents in several different ways; early recognition and diagnosis is essential to improve outcomes. Much of the work in general practice with patients who are suffering from lung cancer involves palliative care, and by managing patients well, GPs can have a big impact on patients’ last days of life.


Introduction 366 Oesophageal cancer 368 Gastric cancer 370 Small intestine and carcinoid tumours 372 Cancer of the liver (hepatocellular cancer) 374 Cancer of the gall bladder and bile ducts 376 Pancreatic cancer 378 Nursing management issues 380 The cancers of the upper gastrointestinal (GI) tract are a diverse group of cancers accounting for around one fifth of all cancers diagnosed in the UK. Improved surgical treatment of early stage disease can offer excellent survival rates, but most patients will present with regional or advanced spread of the disease. The symptoms of many of the upper GI cancers are vague and non-specific and often occur late in the course of the disease. Combined with poor overall responses to chemotherapy and radiotherapy, this makes them difficult to treat; as a result long-term survival rates tend to be low....


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