scholarly journals Risk factors for Barrett’s esophagus in young adults who underwent upper gastrointestinal endoscopy in a health examination center

2019 ◽  
Vol 12 ◽  
pp. 175628481985311 ◽  
Author(s):  
Pin-Chieh Wu ◽  
Yan-Hua Chen ◽  
Fu-Zong Wu ◽  
Kung-Hung Lin ◽  
Chiao-Lin Hsu ◽  
...  

Background: Barrett’s esophagus (BE) is a premalignant condition with increased incidence worldwide both in old and young individuals. However, the role of certain potential risk factors remains unclear in young adults (< 50 years). We aimed to determine the risk factors of BE in young adults. Methods: A total of 4943 young adults who underwent upper gastrointestinal endoscopy at our health check-up center were enrolled. The diagnosis of BE was based on histological confirmation. We analyzed demographic factors, laboratory data, potential risk factors such as smoking, alcohol consumption, presence of gastroesophageal reflux disease (GERD) symptoms, and metabolic syndrome for the risk of BE by using binary logistic regression analysis. Results: The prevalence of BE was 1.8% (88/4943). Male sex, the presence of GERD symptoms, and smoking were three significant risk factors related to BE. Furthermore, participants who had smoked for 10 pack-years or more had increased risk of BE with dose-dependent phenomenon ( p trend < 0.001). The proportion of BE in male participants with both GERD symptoms and a smoking history of 10 pack-years or more was as high as 10.3% (16/155). Conclusions: Significant risk factors of BE in young adults are male sex, the presence of GERD symptoms, and smoking. The risk also increases with an increase in cumulative exposure to smoking.

2021 ◽  
Author(s):  
Leonardo Uchiumi ◽  
Guillermo Mujica ◽  
Daniel Araya ◽  
Juan Carlos Salvitti ◽  
Mariano Sobrino ◽  
...  

Abstract Background: Cystic echinococcosis (CE) is a parasitic zoonosis caused by infection with the larval stage of Echinococcus granulosus sensu lato This study investigated the prevalence and potential risk factors associated with human CE in the towns and rural areas of Ñorquinco and Ramos Mexia, Rio Negro province, Argentina. Methods: In order to detect abdominal CE cysts, we screened 892 volunteers by ultrasound and investigated potential risk factors for CE using a standardized questionnaire. Bivariate and multivariate analyses were used to estimate the Prevalence Ratio (PR) and their 95% CIs of the association between CE and the factors investigated. Results: Abdominal CE was detected in 42/892 screened volunteers (4.7%, CI 3.2-6.1), only two of who being under 15 years of age. Thirteen CE (30.9%) cases had 25 cysts in active stages (CE1, CE2, CE3) The most relevant risk factors identified in the bivariate analysis included: live in rural area (p=0.003), age >40 years (p=0.000), drinking always water of natural source (p=0.007), residing in rural areas during first five years of life (p=0.000) and live more than 20 years at your current address (p=0.013). In the multivariate model, statistically significant risk factors were: frequently touch dogs (p=0.012), residing in rural areas during first five years of life (p=0.004), smoking (p=0.000), age > 60 years (p­­=0.002) and live in rural areas (p=0.017).Conclusions: our results point toward infection with CE being acquired since childhood and with constant exposure throughout life, especially in rural areas with a general environmental contamination


1979 ◽  
Vol 72 (6) ◽  
pp. 409-411 ◽  
Author(s):  
A Kirk ◽  
R Graham-Brown ◽  
R M Perinpanayagam ◽  
R G Smith ◽  
D E Barnardo

A prospective study of fifty-two patients undergoing fibreoptic upper gastrointestinal endoscopy was carried out in order to determine whether bacteraemia was a significant risk. Aerobic and anaerobic blood cultures were performed before, during and after endoscopy. Cultures were also taken from lesions (if any found) in the oesophagus, stomach or duodenum. No significant bacteraemia was identified, and bacterial growth was found in only one upper gastrointestinal lesion.


2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
Samiullah Khan ◽  
Kui Jiang ◽  
Lan-ping Zhu ◽  
Iftikhar-ahmad Khan ◽  
Kifayat Ullah ◽  
...  

A gastric bezoar is a compact mass of indigestible foreign materials that accumulate and consolidate in the stomach; however, it can be found in other sites of the gastrointestinal tract. The causative manner of this condition is complex and multifactorial. The main purpose of the review was to raise awareness among clinicians, particularly gastroenterologists, that patients with certain risk factors or comorbid conditions are predisposed to gastric bezoar formation. Early diagnosis and prompt intervention are crucial to avoid bezoar-induced complications. Upper gastrointestinal endoscopy is the standard diagnostic and therapeutic method for gastric bezoars. However, for large size bezoars, surgical intervention is needed.


2019 ◽  
Vol 27 (1) ◽  
Author(s):  
Amber M Beynon ◽  
Jeffrey J Hebert ◽  
Charlotte Lebouef-Yde ◽  
Bruce F Walker

Abstract Background The one-month prevalence of back pain in children and adolescents has been reported at 33, 28 and 48% at ages 9, 13 and 15 respectively. There are many suspected risk factors and triggers of back pain in young people. Objective The purpose of this scoping review was to identify potential risk factors and potential triggers for back pain in young people. The purpose of part I was to identify potential risk factors for incident and episodic back pain in young people. Part II included all eligible studies with unclear or mixed types of back pain. Methods Due to the vast number of studies on “risk factors” for back pain, a two-part scoping review of the literature was chosen as the best way to summarise the evidence. We adhered to the PRISMA-ScR guideline for scoping reviews. General potential risk factors and triggers for back pain in children and young adults (≤ 24 years) were included, incorporating physical, environmental, and/or physiological factors. A search was conducted using PubMed and Cochrane databases from inception to September 2018, limited to the English language. Within part I, and because of their importance, only the results of the studies that investigated risk factors of incident back pain and back pain episodes are presented. Results The search identified 7356 articles, of which 91 articles were eligible for this scoping review. The majority of the eligible articles had an unclear definition of back pain (results presented in scoping review part II). There were 7 inception cohort studies included and 1 cohort study that met the criteria for part I. The most consistent risk factors for incident and episodic back pain are female sex and older age. Conclusion Due to inconsistent ways of reporting on the type of back pain, no definitive risk factor for back pain has been identified. In general, females often report more symptoms, also for other diseases, and older age is not a useful risk factor as it merely indicates that the onset may not be in childhood. Clearly, the time has come to study the causes of back pain from different angles.


2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
P O-ium

Abstract Introduction Recent increased in the prevalence of behavioral problems among young adults has coincided with the raised of popularity of Internet usage including handheld technologies, electronic game and social media among adolescent. However, these information in Thailand is limited. Therefore, this study aim to investigate the association between social media misused and behavioral problems among adolescent in Thailand. Materials and methods The cross-sectional was conducted at 7 public schools located in Central of Thailand in December 2018. The behavioral problems were assessed by using the Strengths and Difficulties Questionnaire (SDQ). Multiple logistic regression analysis was used to identify the risk factors associated with the behavioral problems. Results The total of 1,118 were enrolled into the study. The prevalence of the social media misused and behavioral problems were 85% and 18.5%, respectively. The prevalence of the subscale behavioral problems were peer problem (21%), emotional problem (19%), hyperactivities (10%) and conduct problem (4%). The independent factors associated with behavioral problems were include sleep problem (OR = 3.3, 95%CI = 2.1-5.1), prosocial behavior (OR = 0.4, 95%CI =0.3-0.6), social media misused (OR = 2.5, 95%CI =1.7-3.8), Facebook addiction (OR = 1.8, 95%CI = 1.1-3.0) and Line addiction (OR = 2.8, 95%CI = 1.5-5.1). Conclusions This study highlight the association between the social media misused and high prevalence of behavioral problems among adolescent in Thailand. The information of the potential risk factors should be inform to all stakeholders for develop and implement the effective intervention for young adults in Thailand. Key messages The association between the social media misused and high prevalence of behavioral problems among adolescent in Thailand. The information of the potential risk factors should be informed to develop and implement the effective intervention for young adults in Thailand.


2018 ◽  
Vol 154 (6) ◽  
pp. S-777
Author(s):  
Aslam Syed ◽  
Heitham Abdul-Baki ◽  
Amy Tang ◽  
Payal Thakkar ◽  
Katie Farah ◽  
...  

2013 ◽  
Vol 58 (6) ◽  
pp. 1668-1675 ◽  
Author(s):  
Feng Liu ◽  
Jian-qiang Liu ◽  
Su-zhi Li ◽  
You-wei Chen ◽  
De-qing Yangzong ◽  
...  

2017 ◽  
Vol 54 (4) ◽  
pp. 305-307 ◽  
Author(s):  
Diego Michelon DE CARLI ◽  
Amanda Faria de ARAUJO ◽  
Renato Borges FAGUNDES

ABSTRACT BACKGROUND: Barrett’s esophagus a complication of gastroesophageal reflux disease (GERD) is a precursor of esophageal adenocarcinoma. The incidence of esophageal adenocarcinoma has been increasing in most Western countries. Rio Grande do Sul (RS), the Southernmost state of Brazil has the highest rates of esophageal cancer with low prevalence of esophageal adenocarcinoma. OBJECTIVE: To investigate the prevalence of Barrett’s esophagus among patients underwent to upper gastrointestinal endoscopy in the last 5 years. METHODS: The records of patients underwent upper gastrointestinal endoscopy between 2011 and 2015 were analyzed. Demographic data, GERD symptoms, endoscopic findings, extension and histological diagnosis of columnar epithelia of the esophagus were recorded. Significance among the variables was accessed by chi-square test and Fisher’s exact test with 95% CI. RESULTS: A total of 5996 patients underwent to upper gastrointestinal endoscopy in the period were included. A total of 1769 (30%) patients with GERD symptoms or esophagitis and 107 (1.8%) with columnar lined esophagus were identified. Except for eight patients, the others with columnar lined esophagus had GERD symptoms or esophagitis. Barrett’s esophagus defined by the presence of intestinal metaplasia occurred in 47 patients; 20 (43%) with segments over 3 cm and 27 (57%) with segments shorter than 3 cm. The global prevalence of Barrett’s esophagus was 0.7% and in GERD patients 2.7%. The odds ratio for the occurrence of columnar lined esophagus in patients with GERD was 30 (95%CI=15.37-63.34). The odds ratio for the presence of intestinal metaplasia in long segments was 8 (95%CI=2.83-23.21). CONCLUSION: GERD patients had a risk 30-folds greater to present columnar lined esophagus than patients without GERD symptoms. Long segments of columnar lined esophagus, had a risk eight-folds higher to have Barrett’s esophagus than short segments. Barrett’s esophagus overall prevalence was 0.7%. In GERD patients, the prevalence was 2.7%. Long Barrett’s esophagus represented globally 0.3% and 1.1% in GERD patients.


2020 ◽  
Vol 41 (S1) ◽  
pp. s68-s69
Author(s):  
Karen Jones ◽  
Yi Mu ◽  
Qunna Li ◽  
Allan Nkwata ◽  
Minn Soe ◽  
...  

Background: The Centers for Disease Control and Prevention’s National Healthcare Safety Network (NHSN) has included surveillance of laboratory-identified (LabID) methicillin-resistant Staphylococcus aureus (MRSA) bacteremia events since 2009. In 2013, the Centers for Medicare & Medicaid Services (CMS) began requiring acute-care hospitals (ACHs) that participate in the CMS Inpatient Quality Reporting program to report MRSA LabID events to the NHSN and, in 2015, ACHs were required to report MRSA LabID events from emergency departments (EDs) and/or 24-hour observation locations. Prior studies observed a decline in hospital-onset MRSA (HO-MRSA) rates in national studies over shorter periods or other surveillance systems. In this analysis, we review the national reporting trend for HO-MRSA bacteremia LabID events, 2010–2018. Method: This analysis was limited to MRSA bacteremia LabID event data reported by ACHs that follow NHSN surveillance protocols. The data were restricted to events reported for overall inpatient facility-wide and, if applicable, EDs and 24-hour observation locations. MRSA events were classified as HO (collected >3 days after admission) or inpatient or outpatient community onset (CO, collected ≤3 days after admission). An interrupted time series random-effects generalized linear model was used to examine the relationship between HO-MRSA incidence rates (per 1,000 patient days) and time (year) while controlling for potential risk factors as fixed effects. The following potential risk factors were evaluated: facility’s annual survey data (facility type, medical affiliation, length of facility stay, number of beds, and number of intensive care unit beds) and quarterly summary data (inpatient and outpatient CO prevalence rates). Result: The number of reporting ACHs increased during this period, from 473 in 2010 to 3,651 in 2018. The crude HO-MRSA incidence rates (per 1,000 patient days) have declined over time, from a high of 0.067 in 2011 to 0.052 in 2018 (Table 1). Compared to 2014, the adjusted annual incidence rate increased in 2015 by 16.38%, (95% confidence interval [CI], 10.26%–22.84%; P < .0001). After controlling for all significant risk factors, the estimated annual HO-MRSA incidence rates declined by 5.98% (95% CI, 5.17%–6.78%; P < .0001) (Table 2). Conclusions: HO-MRSA bacteremia incidence rates have decreased over the past 9 years, despite a slight increase in 2015. This national trend analysis reviewed a longer period while analyzing potential risk factors. The decline in HO-MRSA incidence rates has been gradual; however, given the current trend, it is not likely to meet the Healthy People 2020 objectives. This analysis suggests the need for hospitals to continue and/or enhance HO-MRSA infection prevention efforts to reduce rates further.Funding: NoneDisclosures: None


2020 ◽  
Vol 70 (4) ◽  
pp. 1797
Author(s):  
O.B. INCE ◽  
T. TÜRK

Lumpy skin disease (LSD) is caused by the virus of the same name and has major economic impacts on cattle breeding. In Turkey, frequent cases of cattle LSD have been reported over the last years. The present study aimed to analyze potential risk factors for LSD and provide information for controlling the spread of infectious diseases by a geographic information system (GIS). The research included cross-sectional and retrospective studies with active disease follow-up and semi-structured interviews (SSI) from August 2013 to December 2014 in Turkey. Potential risk factors for LSD were evaluated based on environmental conditions and provincial demographic and epidemiological data. Of the total of 562 observed animals, 27.22% and 2.67% of cattle were sick and died due to LSD, respectively. The morbidity rate was 26.04% in mixed and 38.18% in local breeds. The animal-level prevalence significantly differed among animals of different age, sex, and with different vaccination status (P<0.05). It was more serious in younger animals and females and during drier weather conditions. A trend of seasonality was observed in LSD occurrence. Significant risk factors affecting the prevalence of LSD were proximity to the southern border of Turkey, animal movements, and animal markets. In this process, geographical query, analysis, and thematic map production were performed by GIS.


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