Translational and emerging clinical applications of metabolomics in cardiovascular disease diagnosis and treatment

2016 ◽  
Vol 23 (15) ◽  
pp. 1578-1589 ◽  
Author(s):  
Anthony C Dona ◽  
Sean Coffey ◽  
Gemma Figtree
2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Hairong Chen ◽  
Qiuguo Zou ◽  
Qi Wang

On a global scale, cardiovascular disease has become one of the most serious diseases that endangers human health and causes death and seriously threatens human life and health. If we can make accurate, timely, and effective judgments on cardiovascular-related parameters and take corresponding effective measures, the incidence of cardiovascular diseases can be reduced to a large extent. Based on this, this paper proposes the clinical application research of ultrasound virtual reality technology in the diagnosis and treatment of cardiovascular diseases. This article uses literature methods, experimental research methods, mathematical statistical analysis methods, and other research methods and in-depth study of virtual reality technology, cardiovascular disease, and other theoretical knowledge and briefly introduces ultrasound image denoising algorithms, such as bilateral filtering and PM model. And on this basis, it establishes clinical trials of ultrasound virtual reality technology in the diagnosis and treatment of cardiovascular diseases. This article mainly analyzes the application of virtual reality technology, technology comparison, and the experimental results carried out in this article. From the survey results, the total prevalence of hypertension was 25.1%, and the prevalence of males and females was 25.9% and 24.4%, respectively; the diagnostic accuracy rate of the experimental group reached 85.39%, while the diagnostic accuracy rate of the control group was 76.8%. It shows that the use of ultrasound virtual reality technology for disease diagnosis can effectively improve the accuracy of cardiovascular disease diagnosis and reduce the proportion of misdiagnosis and missed detection.


2018 ◽  
Vol 9 (1) ◽  
pp. 8
Author(s):  
Bernardo Almeida

Snapping hip syndrome is a condition in which the predominant symptom is the snapping feelingaround the hip joint caused by a dynamic impingement between muscles or tendons and boneprominences. The etiology of the snapping hip types and consequently the therapeutic targets havebeen subjects of discussion and controversy along the years. A careful clinical history and physicalexamination is frequently enough for this disease diagnosis. Treatment is typically conservative,however when it is not successful surgical treatment is indicated, consisting on the snapping muscleor tendons lengthening. The authors review in this paper the current scientific literature about functionalanatomy, physiopathology, symptoms, diagnosis and treatment of snapping hip.


Metabolites ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 159
Author(s):  
Yao Peng ◽  
Yuqiang Nie ◽  
Jun Yu ◽  
Chi Chun Wong

Colorectal cancer (CRC) is one of the leading cancers that cause cancer-related deaths worldwide. The gut microbiota has been proved to show relevance with colorectal tumorigenesis through microbial metabolites. By decomposing various dietary residues in the intestinal tract, gut microbiota harvest energy and produce a variety of metabolites to affect the host physiology. However, some of these metabolites are oncogenic factors for CRC. With the advent of metabolomics technology, studies profiling microbiota-derived metabolites have greatly accelerated the progress in our understanding of the host-microbiota metabolism interactions in CRC. In this review, we briefly summarize the present metabolomics techniques in microbial metabolites researches and the mechanisms of microbial metabolites in CRC pathogenesis, furthermore, we discuss the potential clinical applications of microbial metabolites in cancer diagnosis and treatment.


Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1233
Author(s):  
Ernest Osei ◽  
Kwasi Agyei ◽  
Boikhutso Tlou ◽  
Tivani P. Mashamba-Thompson

Mobile health (mHealth) technologies have been identified as promising strategies for improving access to healthcare delivery and patient outcomes. However, the extent of availability and use of mHealth among healthcare professionals in Ghana is not known. The study’s main objective was to examine the availability and use of mHealth for disease diagnosis and treatment support by healthcare professionals in the Ashanti Region of Ghana. A cross-sectional survey was carried out among 285 healthcare professionals across 100 primary healthcare clinics in the Ashanti Region with an adopted survey tool. We obtained data on the participants’ background, available health infrastructure, healthcare workforce competency, ownership of a mobile wireless device, usefulness of mHealth, ease of use of mHealth, user satisfaction, and behavioural intention to use mHealth. Descriptive statistics were conducted to characterise healthcare professionals’ demographics and clinical features. Multivariate logistic regression analysis was performed to explore the influence of the demographic factors on the availability and use of mHealth for disease diagnosis and treatment support. STATA version 15 was used to complete all the statistical analyses. Out of the 285 healthcare professionals, 64.91% indicated that mHealth is available to them, while 35.08% have no access to mHealth. Of the 185 healthcare professionals who have access to mHealth, 98.4% are currently using mHealth to support healthcare delivery. Logistic regression model analysis significantly (p < 0.05) identified that factors such as the availability of mobile wireless devices, phone calls, text messages, and mobile apps are associated with HIV, TB, medication adherence, clinic appointments, and others. There is a significant association between the availability of mobile wireless devices, text messages, phone calls, mobile apps, and their use for disease diagnosis and treatment compliance from the chi-square test analysis. The findings demonstrate a low level of mHealth use for disease diagnosis and treatment support by healthcare professionals at rural clinics. We encourage policymakers to promote the implementation of mHealth in rural clinics.


Sign in / Sign up

Export Citation Format

Share Document