scholarly journals Ultrasound-guided radiofrequency ablation of genicular nerves of knee for relief of intractable pain from knee osteoarthritis: a case series

2017 ◽  
Vol 12 (3) ◽  
pp. 145-154 ◽  
Author(s):  
Arif Ahmed ◽  
Divesh Arora

Introduction: The knee arthroplasty is the best option for patients with advanced osteoarthritis who have failed all other conservative options, but regrettably many patients fail to undergo surgery due to co-morbidities or other reasons. So, new alternative modes are always in demand for these patients. Methods: The ultrasound-guided radiofrequency ablation (RFA) of all the genicular nerves of knee joint was done in patients with grade III and IV osteoarthritis of knee joint, with severe pain (numerical rating scale (NRS) > 7) who had failed conservative management and intra-articular injections after a positive genicular nerve block with local anaesthetics. The demographics, pain intensity measured in NRS, Oxford Knee Score (OKS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and quality of life measured by 36-Item Short Form Health Survey (SF-36) questionnaire was measured at baseline and at regular intervals. Results: The average age of the patients was 61.50 ± 6.75 years. There was significant improvement in pain intensity at rest, movement and on weight bearing from 8.75 ± 0.5, 9.0 ± 0.0, and 9.0 ± 0.0 at baseline to 2.38 ± 0.51, 3.75 ± 0.46, and 4.13 ± 0.35 at 1 month and 3.13 ± 0.64, 4.38 ± 0.51, and 4.63 ± 0.51 at 6 months after the procedure, respectively (p value <0.05). The OKS had improved from 7.75 ± 1.25 at baseline to 28.88 ± 2.53 and 28.13 ± 1.80 at 1 and 6 months, respectively, after the procedure (p value <0.05). The WOMAC score had also improved significantly from 77.75 ± 4.34 at baseline to 38.38 ± 5.82 and 39.25 ± 5.12 at 1 and 6 months, respectively (p value <0.05). There was also significant improvement in the quality of life after the procedure (p value <0.05). Conclusion: Ultrasound-guided RFA of genicular nerves of knee joint is a good alternative option for patients who are having severe pain and disability from knee osteoarthritis and gives a long-lasting pain relief for more than 6 months.

2021 ◽  
Vol 21 (3) ◽  
Author(s):  
Satyendra K. TIWARY ◽  
Sartaz ALAM ◽  
Pankaj SUREKA ◽  
Puneet KUMAR ◽  
Ajay K. KHANNA

Author(s):  
Hari Peni Julianti ◽  
◽  
Dea Amarilisa Adespin ◽  
Trilaksana Nugroho ◽  
Nur Laelatul Rasyidin ◽  
...  

ABSTRACT Background: Osteoarthritis (OA), especially knee OA, is the fourth cause of disability in the world. OA affected the daily physical activity and quality of life of the patients. This study aimed to analyze the various factors that affect nutritional, physical, psychosocial, and comorbid disease affecting quality of life in knee osteoarthritis patients at William Booth hospital, Semarang, Central Java. Subjects and Method: This was a cross-sectional study conducted at William Booth Hospital, Semarang, Central Java. A sample of 79 patients with knee osteoarthritis was selected by simple random sampling. The dependent variable was the quality of life. The independent variables were age, nutritional status, pain intensity, radiological features, family function, length of illness, unilateral/ bilateral OA knee, hypertension, and diabetes mellitus. The data were analyzed by chi-square. Results: Osteoarthritis in elderlies was significantly associated with age (p <0.001), nutritional status (p <0.001), pain intensity (p <0.001), radiological features (p= 0.020), and family function (p <0.001). Osteoarthritis in elderlies was insignificantly associated with length of illness (p= 0.445), unilateral/ bilateral OA knee (p= 0.153), hypertension (p= 0.272), and diabetes mellitus (p= 0.617). Conclusion: Osteoarthritis in elderlies is significantly associated with age, nutritional status, pain intensity, radiological features, and family function, but insignificantly associated with length of illness, unilateral/ bilateral OA knee, hypertension, and diabetes mellitus. Keywords: elderly, osteoarthritis, quality of life Correspondence: Hari Peni Julianti. Faculty of Medicine, Universitas Diponegoro. Jl. Prof Sudarto SH, Tembalang, Semarang, Central Java. Email: [email protected]. Mobile: +62813263-81347. DOI: https://doi.org/10.26911/the7thicph.05.36


2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Vahideh Toopchizadeh ◽  
Neda Dolatkhah ◽  
Dawood Aghamohammadi ◽  
Mahrokh Rasouli ◽  
Maryam Hashemian

Abstract Objectives We aim to measure dietary inflammatory index (DII) and its association with functional status, pain intensity and quality of life (QOL) in patients with knee osteoarthritis (KOA). Dietary information from 220 qualified patients with KOA was collected by a 168-item food frequency questionnaire. The functional status, pain intensity and QOL were evaluated by Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire, Visual Analogue Scale (VAS) and SF36 questionnaire respectively. Results Linear regression analysis showed that the DII was significantly associated with VAS (p = 0.040; β = 0.151), and physical function (p = 0.039; β = − 0.184), emotional wellbeing (p = 0.048; β = − 0.158) and pain (p = 0.020; β = 0.161) scales and physical health (p = 0.047; β = 0.110) subscale of QOL after adjusting for age, sex, body mass index, and physical activity. There was no significant differences concerning WOMAC across the DII tertiles with and without adjustment to probable confounders (Ptrend = 0.091 and 0.181, respectively). After adjustment, a significantly increased severe pain odds was observed in the highest tertile of DII score in comparison with the lowest tertile (OR tertile 3 vs. 1 = 1.55, 95% CI 1.04–2.31; Ptrend = 0.04).


2021 ◽  
pp. 164-166
Author(s):  
Suprabha Chaudhary ◽  
Kumar Ashish ◽  
Manish Manish ◽  
Robbins Kumar

Mastalgia is one of the most common presenting symptom in female attending surgical and gynaecological OPD. In majority of patients it can be managed with reassurance and simple medication. But in 10-20 % of patient severe pain affects quality of life and causes severe anxiety. Aim was to compare the effectiveness of Centchroman and Danazol in mastalgia by using visual analogue scale (VAS), Fifty-two patients were taken in study & randomized into two groups with all women presenting with mastalgia with VAS score ≥3 between ages of 20-40 years. Centchroman (30mg OD for 3 months) in group 1 and Danazol (50 mg bid for 3 months) to group 2 was given and were monitored for VAS for pain and we found that centchroman is more effective than danazol and there was signicant difference in parameters in both the groups as Age, VAS th score, duration of menstrual cycle, No. of cases with cyclical, non-cyclical mastalgia. Relative risk (RR) of 1.256 at 12 week, 2.280 at th 24 week were noted, P value was found to be signicant. It can be concluded that Centchroman therapy is a safe, equally effective, and less costly alternative to Danazol for the treatment of mastalgia.


Author(s):  
Antonio Oliviero ◽  
Lorenzo Giordano ◽  
Nicola Maffulli

Abstract Background Osteoarthritis (OA) is a most common orthopaedic condition, often complicated by inflammatory features. Sources of data A systematic search in PubMed, Embase, Google Scholar and Scopus databases (to January 2019) was performed to define the effect obtained in patients with OA of the knee by injections of ozone, on pain and physical function. Six RCTs and 353 patients were included. Areas of agreement Recently, an increasing number of physicians have used ozone therapy to alleviate the symptoms of acute and chronic OA of the knee. Ozone can allow greater mobility of the knee joint, pain relief and decrease in effusion. Areas of controversy The volume and concentration of ozone injected are different in the various treatment protocols published. Growing points The action of ozone is unclear, but it is a promising therapeutic modality capable of impacting, favourably, function and quality of life. Areas timely for developing research The lack of a clear protocol of use is a major limitation, and to date there is no clear evidence of long-term efficacy.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Fenglan Wang ◽  
Xiaoli Zhang ◽  
Xiao Tong ◽  
Min Zhang ◽  
Fengmei Xing ◽  
...  

Abstract Background Exercise is recommended as a principal treatment for individuals with knee osteoarthritis (KOA). However, the best choice for an optimal exercise program able to promote long-term compliance in KOA patients is not clear. This study aims to compare the effect of combined exercise (CE: quadriceps strengthening exercises (QSE) and Baduanjin qigong training (BDJ)) versus QSE alone and BDJ alone on older adults with KOA. Methods A three-arm, quasi-experimental trial with repeated measurements was used. As a cluster randomized trial, participants from three community centers were assigned respectively to QSE group, BDJ group and CE group. We assessed pain intensity, physical function, self-efficacy, and health-related quality-of-life (HRQoL) using standardized instruments at baseline, 3 months and 6 months follow-up. Results One hundred and twenty-eight participants with KOA aged over 60 completed the study. Over the 6 months, there were significant group interaction effects on pain intensity (F = 28.888, P < 0.001), physical function (F = 26.646, P < 0.001), and self-efficacy (F = 22.359, P < 0.001), and, based on a short form-12 item health survey questionnaire (SF-12), physical component summary (F = 7.470, P < 0.001), and mental component summary (F = 10.207, P < 0.001). Overall, the CE group exhibited significantly greater improvement in all outcomes when compared to the QSE group and the BDJ group. Conclusions CE treatment is more effective than QSE and BDJ in pain relief, increasing physical function, improving self-efficacy, and raising quality-of-life in community-dwelling KOA older adults. Moreover, it promotes long-term compliance in KOA community patients. Trial registration Chinese Clinical Trails Registry number ChiCTR2000033387 (retrospectively registered). Registered 30 May 2020.


2020 ◽  
Vol 1 (2) ◽  
pp. 29-34
Author(s):  
Mahnaz Ahangari ◽  
Amin Norouzi Fashkhami ◽  
Hamid Zinalpoor ◽  
Hamed Ahangari ◽  
Mohamad Reza Minator Sajjadi

Introduction: Today, increased degenerative disease of the knee, which reduces the efficiency of the activity and quality of life, is one of the most common causes of many population complaints. It is important to properly plan and carry out non-invasive and non-pharmacological therapies to treat the pain and its consequences.  The question of which of methods effectively relieves pain, improve function and efficiently increases life quality led to a comparison of two methods, interferential and ultra-reiz (Träbert) currents therapy. Methods: Randomized Block clinical trial carried out at Taleghani general hospital Shahid Beheshti University of Medical Sciences from November 2017 to February 2019. The study included 104 patients of both sexes, aged 38-74 years, with knee osteoarthritis. They were selected based on exclusion and inclusion criteria. The patients were randomly assigned to two groups: A and B.  Group A, n: 52 patients, were received ultra-reiz current, and group B, n: 52 patients, were subjected to interferential current. Parameters assessment were evaluated by the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire with 5 domains:  pain, symptoms, ADL, sports/recreational activity, and quality of life. Data were collected at the 1st session and at the end of treatment (at least three times a week). The obtained results were subject to statistical analysis. Results: Data were analyzed in SPSS software by using paired and two independent sample t-test. The mean scores before and after treatment with p-value range 0.002~0.764 showed that there were differences in pain, other symptoms, ADL, sport/recreational activity, and quality of life status between ultra-reiz and IFT groups, but the results were statistically more significant in the ultra-reiz group (p < 0.0001). Conclusions: Our study showed that ultra-reiz and IFT were effective for patients with knee OA, but ultra-reiz became a more effective modality than IFT in OA patients.


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