scholarly journals An overview of the phytoestrogen effect on vaginal health and dyspareunia in peri- and post-menopausal women

2019 ◽  
Vol 25 (1) ◽  
pp. 11-20 ◽  
Author(s):  
Fatemeh R Dizavandi ◽  
Masoumeh Ghazanfarpour ◽  
Nasibeh Roozbeh ◽  
Leila Kargarfard ◽  
Talat Khadivzadeh ◽  
...  
Keyword(s):  
Similar Efficacy ◽  
Cochrane Central Register ◽  
Vaginal Atrophy ◽  
Pueraria Mirifica ◽  
Menopausal Women ◽  
Significant Difference ◽  
Vaginal Health ◽  
Post Menopausal ◽  
Intermediate Cells ◽  
Conjugated Estrogen

Objective The aim of this overview was to evaluate the effectiveness of phytoestrogens on vaginal health and dyspareunia in peri- and post-menopausal women. Material and methods Three databases including MEDLINE, Scopus and the Cochrane Central Register of Controlled Trials were from inception to August 2017. Result Two systematic reviews and 11 RCTs were included in the overview. According to the findings, isoflavones increased the maturation value and attenuated the vaginal atrophy in the post-menopausal women. Topical isoflavones had beneficial effects on the vaginal atrophy. Similar efficacy was found in Pueraria mirifica and conjugated estrogen cream on dryness ( p = 0.277), soreness ( p = 0.124) and irritation ( p = 0.469), as well as discharge ( p = 0.225) and dyspareunia ( p = 0.089). However, the conjugated estrogen cream was more effective compared to Pueraria mirifica ( p > 0.005) regarding maturation index improvement. Comparison of fennel 5% vaginal cream and placebo gel showed significant difference in superficial cells ( p < 0.01), parabasal cells ( p < 0.01) and intermediate cells ( p < 0.01), whereas no difference was found between the oral fennel and placebo in terms of superficial, parabasal and intermediate cells as well as Maturation value. Administration of 80 mg red clover oil had a significant effect on superficial ( p < 0.005), intermediate ( p < 0.005) and parabasal and vaginal dryness ( p < 0.005) compared to the placebo. Flaxseed had also a trivial effect on maturation value. Genistein had a more prominent effect on the genital score. The severity of dyspareunia decreased by 27%. Conclusion Phytoestrogens have various effects based on administration route and type on the vaginal atrophy.

Non-hormonal treatment of vulvo-vaginal atrophy-related symptoms in post-menopausal women

2015 ◽  
Vol 35 (8) ◽  
pp. 835-838 ◽  
Author(s):  
C. Tersigni ◽  
N. Di Simone ◽  
E. Tempestilli ◽  
F. Cianfrini ◽  
R. Russo ◽  
...  
Keyword(s):  
Hormonal Treatment ◽  
Vaginal Atrophy ◽  
Menopausal Women ◽  
Post Menopausal

scholarly journals Assessment of effectiveness of spinal exercises and body mechanics on low back pain among post menopausal women

2015 ◽  
Vol 1 (4) ◽  
pp. 191 ◽  
Author(s):  
Angel Rajakumari G ◽  
Soli T. K. ◽  
Malathy D
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Control Group ◽  
Low Back ◽  
Menopausal Women ◽  
Significant Difference ◽  
Post Test ◽  
Quasi Experimental ◽  
Equivalent Control ◽  
Post Menopausal

Aim: To assessment of effectiveness of spinal exercises and body mechanics on low back pain among post menopausal women.Participants and setting: A quasi experimental non equivalent control group pretest post test design was adapted. The study was conducted in the urban area of suryapet. 40 post menopausal women who fulfilled the inclusion criteria were selected by nonprobability purposive sampling technique.Intervention: The intervention such as spinal exercises and body mechanics were performed to overcome the level of low back pain among post menopausal women. The pre and post assessment was done by using a combined numerical and categorical pain scale.Measurement and findings: The women completed the demographic and obstetrical information and pain was measured by 0- 10 Modified combined numerical categorical pain intensity scale. This study revealed that there was high significant difference found in low back pain at p<0.001level between study group.Conclusion: The overall findings in the present study revealed that the spinal exercises and body mechanics was effectives and had brought about significant change in the reduction of low back pain among post menopausal women compared to pre test level of low back pain.

scholarly journals Macro-regional variation in attitudes toward and experiences of vulvar and vaginal atrophy among Italian post-menopausal women: a post hoc analysis of REVIVE survey data

2017 ◽  
Vol 33 (5) ◽  
pp. 389-394 ◽  
Author(s):  
Rossella E. Nappi ◽  
Martire Particco ◽  
Nicoletta Biglia ◽  
Angelo Cagnacci ◽  
Costantino Di Carlo ◽  
...  
Keyword(s):  
Survey Data ◽  
Regional Variation ◽  
Vaginal Atrophy ◽  
Post Hoc Analysis ◽  
Menopausal Women ◽  
Post Menopausal ◽  
Post Hoc

Effects of Hormone Replacement Therapy on Muscle Performance and Balance in Post-Menopausal Women

1996 ◽  
Vol 91 (6) ◽  
pp. 685-690 ◽  
Author(s):  
Alison L. Armstrong ◽  
Janet Oborne ◽  
Carol A. C. Coupland ◽  
Marion B. MacPherson ◽  
E. Joan Bassey ◽  
...  
Keyword(s):  
Hormone Replacement Therapy ◽  
Replacement Therapy ◽  
Hormone Replacement ◽  
Test Group ◽  
Muscle Performance ◽  
Control Group ◽  
Menopausal Women ◽  
Significant Difference ◽  
Post Menopausal ◽  
Leg Extensor Power

1. A randomized controlled trial of the effect of oral hormone replacement therapy plus calcium compared with calcium alone on balance, muscle performance and falls was conducted over 48 weeks in 116 post-menopausal women (aged 45–70 years), all of whom had suffered a distal radial fracture during the previous 3 months. Treatment was with Prempak C or Premarin 0.625 mg in the test group with 1 g calcium daily (Sandocal) in both groups. Measurements were made of balance, assessed as sway, leg extensor power and self-paced walking speed, at 12-week intervals over 24 weeks. Hand grip strength was measured every 12 weeks for 48 weeks, and falls in the preceding 12 weeks were recorded at each visit. 2. There was no relation between initial levels of oestradiol and any other variable assessed, except body mass. Levels of follicle-stimulating hormone in the test group were in the premenopausal range. There was no significant change attributable to hormone replacement therapy at any time point in any of the outcome variables. The only significant difference was an increase of 4.2% (95% confidence interval 0.7–7.6%) in leg extensor power in the control group (calcium alone) compared with the group treated with hormone replacement therapy. 3. Of the total group, 37% fell again during the year, with three patients suffering a further fracture. Frequent fallers swayed significantly more often than the others, but there was no evidence that their muscle strength was poorer or that the group treated with hormone replacement therapy fell less frequently. 4. Hormone replacement therapy did not increase muscle performance, improve balance or reduce falls over a year in middle-aged women.

scholarly journals Effect of Stretching and Strengthening Protocol on Forward Flexed Posture in Post-Menopausal Women

2021 ◽  
pp. 306-314
Author(s):  
Sharvari Sahasrabuddhe ◽  
Sandeep B. Shinde ◽  
Pradnya P. Ghadage
Keyword(s):  
Selection Criteria ◽  
Exercise Protocol ◽  
Post Intervention ◽  
Forward Head Posture ◽  
Postural Changes ◽  
Strengthening Exercise ◽  
Menopausal Women ◽  
Significant Difference ◽  
Post Menopausal ◽  
Craniovertebral Angle

Background: Forward flexed posture is one of the most common structural change which occurs during menopause due to osteoporosis. Stretching and strengthening of cervical and thoracic spine muscles helps to alter the postural changes and maintain COG. This study thus, aims to see the effectiveness of the structured exercise protocol in post-menopausal women. Aims and Objective: To study the effectiveness of supervised and non-supervised stretching and strengthening protocol in post-menopausal women with forward posture. Materials and Methods: A total 40post-menopausal women with forward head posture were selected on the basis of selection criteria. They were randomly allocated in two groups A) Supervised Group= 20, B) Unsupervised Group=20 each. Forward flexed posture was assessed using Occiput to Wall Test and Craniovertebral Angle. Treatment was explained to both the groups. The pre and post measurements of the participants were recorded. Results: Statistical analysis was performed using the unpaired t test. Occiput to wall test and craniovertebral angle were used as the outcome measures for determining the effect of stretching and strengthening on forward neck posture. Comparing the pre-intervention and post-intervention values of occiput to wall test, a significant difference was seen following administration of protocol (p<0.0001). For craniovertebral angle, a significant difference was seen between pre-intervention and post-intervention values (p<0.0001). Also, it was seen that there was a significantly higher difference in the values of craniovertebral angle and occiput to wall test values in the supervised groups as compared to the unsupervised group. Conclusion: The current study demonstrated the effect of stretching and strengthening exercise in improving postural kyphosis in post-menopausal women. In addition, all variables of interest showed statistically significant post-treatment improvements in supervised group than unsupervised group.

scholarly journals Comparison of risk profile in pre-menopausal and post-menopausal women with acute coronary syndrome

2020 ◽  
Vol 8 (5) ◽  
pp. 1612
Author(s):  
Sandeep Chhabra ◽  
Harmeet Pal S. Dhooria ◽  
Avantika Garg ◽  
Gurdeep S. Dhooria
Keyword(s):  
Diabetes Mellitus ◽  
Cardiovascular Disease ◽  
Acute Coronary Syndrome ◽  
Risk Factor ◽  
Physical Inactivity ◽  
Risk Factor Profile ◽  
Coronary Syndrome ◽  
Menopausal Women ◽  
Significant Difference ◽  
Post Menopausal

Background: The physiological changes associated with menopause are responsible for increase in cardiovascular disease after menopause. BMI, physical inactivity, metabolic syndrome, hypertension and diabetes mellitus increase in post-menopausal women which are all powerful predictors of cardiovascular events. The risk factor profile between pre-menopausal and post-menopausal women presenting with acute coronary syndrome was thus studied.Methods: This study was a prospective cross-sectional hospital based study and was conducted in the Department of Medicine and Department of Cardiology, Dayanand Medical College and Hospital, Ludhiana wherein 50 pre-menopausal women and 50 post- menopausal women who presented with acute coronary syndrome were enrolled. The risk factor profile and angiography findings amongst the 2 groups were compared.Results: There was no difference in the incidence of Diabetes Mellitus and Hypertension among the pre & post-menopausal groups. The prevalence of family history of cardiovascular disease was higher in the pre-menopausal group. The post-menopausal women showed a significant decrease in physical activity due to sedentary lifestyle. Both the groups had high BMI and increased waist circumference. Lipid parameters did not show any significant difference between the two groups. However, pre-menopausal women had higher LDL-C and triglyceride levels and lower HDL-C levels. On analysis of the angiographic findings in diabetics and non-diabetics, of both the groups diabetes mellitus was much higher in subjects presenting with triple vessel disease suggesting extensive atherosclerosis.Conclusions: study showed physical inactivity as an important cardiovascular risk factor in post-menopausal women. Obesity is an important risk factor for coronary artery disease in both pre- and post-menopausal women.

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