Perinatal Asphyxia Among Neonates Admitted Jimma Medical Center, Jimma, Ethiopia

Background: Perinatal asphyxia is a severe problem which causes serious problem in neonates in developing countries. This study is aimed to determine magnitude of perinatal asphyxia and its associated factors. Methods: A cross-sectional study design was conducted among neonates admitted over a period of 4 years on 740 samples. Systematic sampling method was employed to get required samples from log book. Epi-data 3.1 is used for data entry and the entered data was exported to SPSS Version 23 for analysis. Bivariable and multiple variable logistic regressions analysis were applied to see the association between dependent and independent variables. Finally, P-value <.05 at 95% CI was declared statistically significant. Results: The main significant factor associated to perinatal asphyxia were prolonged labor ( P = .04, AOR = 1.68 95%CI: [1.00, 2.80]), being primipara ( P = .003, AOR = 2.06, 95%CI: [1.28, 3.30]), Small for Gestational Age (SGA) ( P = .001, AOR = 4.35, 95%CI: [1.85, 10.19]), Large for Gestational Age ( P = .001, AOR = 16.75, 95%CI: [3.82, 73.33]) and mode of delivery. Conclusion: The magnitude of perinatal asphyxia was 18%. Prolonged labor, parity, birth size, mode of delivery, and APGAR score at 1st minute were significantly associated with perinatal asphyxia. So, Nurses, Midwives, Medical Doctors, and health extension workers have to engage and contribute to on how to decrease the magnitude of perinatal asphyxia.

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Electrolyte abnormalities in asphyxiated newborns

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20181537 ◽

2018 ◽

Vol 5 (3) ◽

pp. 1036

Author(s):

Satheesh Kumar D. ◽

Thenmozhi M. ◽

Kumar .

Keyword(s):

Serum Sodium ◽

Perinatal Asphyxia ◽

Mode Of Delivery ◽

Birth Asphyxia ◽

Neonatal Morbidity ◽

Postnatal Period ◽

P Value ◽

Sodium Potassium ◽

Neonatal Deaths ◽

Electrolyte Abnormalities

Background: Perinatal asphyxia is the most common cause of neonatal morbidity and mortality in worldwide. It accounts for 23% of all neonatal deaths. Electrolyte abnormalities are more common in the immediate post asphyxiated period and influence neonatal the outcome effectively. Aim of this study was to measure the serum sodium, potassium and calcium levels in immediate postnatal period of asphyxiated newborns and assess the correlation with different degree of birth asphyxia.Methods: The serum sodium, potassium and calcium levels were measured in asphyxiated newborns in the early post-natal period. Both intramural and extramural newborns were included irrespective of their mode of delivery but according to the Apgar score. The measured electrolyte values were compared with the different severity of asphyxia. Results: Out of 100 newborns 53 had hyponatremia, 10 had hyperkalemia and 3 had hypocalcemia. The serum sodium and potassium levels showed significant P value (<0.00) with the different degree of both asphyxia but calcium levels were not significant (p valve = 0.06). There was a negative linear correlation with sodium and calcium levels and positive correlation with the serum potassium levels.Conclusions: Hyponatremia was significant in all stages of birth asphyxia, hyperkalemia was significant with increased severity of birth asphyxia and hypocalcemia was only weakly significant even in severe birth asphyxia.

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Influence of Family Structure and Functionality on Immunization Status of Infants Attending GOPC of BMC Saki

Research Journal of Health Sciences ◽

10.4314/rejhs.v8i3.2 ◽

2020 ◽

Vol 8 (3) ◽

pp. 163-174

Author(s):

A.I. Bolaji ◽

T.O. Ojebode ◽

O.S. Adekanye ◽

A.O. Bolaji

Keyword(s):

Family Structure ◽

Medical Center ◽

Sampling Technique ◽

Family Type ◽

Systematic Sampling ◽

P Value ◽

Cross Sectional ◽

Immunization Status ◽

Study Population ◽

Family Functionality

Introduction: Vaccine-preventable diseases are endemic in Nigeria, and contribute greatly to childhood morbidities and mortalities. Good family structure has been reported to improve children's wellbeing, health and eating habit, but the contribution of family structure together with family functionality on immunization status has not been documented. Overall, the goal of the research was to determine the level of immunization status in the study population, assess their knowledge of immunization and determine what influence family structure and functionality have on children's immunization status.Methods: A cross-sectional descriptive study was conducted in 2016 in the General outpatient clinic (GOPC) of Baptist Medical Centre (BMC), Saki, Oyo State. Family APGAR Scale and self-design questionnaire were used to collect data from 299 respondents using systematic sampling technique. A SPSS (version 21) was used for the analysis.Results: Our results showed that 82.9% of the respondents were fully immunized and 98% had knowledge about Immunization. Majority of the respondents came from functional families, accounting for 85.6% of cases. The following factors were found to be statistically significantly associated with immunization status: family functionality (X2 = 101.694, P = 0.000), family type (p value =0.000), family size (p value = 0.000), ethnic group (p value = 0.000) and number of children (P value = 0.000)Conclusion: Our findings showed that there is an adequate knowledge of immunization in the study population, and that a child's immunization status is significantly influenced by the family structure and functionality. However, given the fact that this is a single, hospital-based study, several multi-center studies would have to be employed not just to validate this conclusion but also to inform policy making. Keywords: Immunization status, family structure, family functionality, vaccine, health facility, Nigeria French Title: Influence de la structure familiale et de la fonctionnalité sur le statut de vaccination des nourrissons assistant au GOPC de BMC, Saki Les morts évitables par la vaccination restent endémiques et contribuent de manière significative à la morbidité infantile au Nigéria et il a été reconnu qu'une bonne structure familiale améliore le bien-être, la santé et les habitudes alimentaires des enfants, mais la contribution de la structure et de la fonctionnalité de la famille au statut vaccinal n'est pas encore établie. Le but de cette étude est de déterminer le niveau d'immunisation des répondants, d'évaluer leurs connaissances en matière d'immunisation et de déterminer l'influence de la structure et de la fonctionnalité de la famille sur l'état de vaccination. Méthode de l'étude: Une étude descriptive transversale a été menée en 2016 dans la clinique externe générale (GOPC) du Baptist Medical Center (BMC), Saki, dans l'état d'Oyo. L'échelle familiale APGAR et le questionnaire d'auto-conception ont été employés pour recueillir des données auprès de 299 répondants à l'aide d'une technique d'échantillonnage systématique. Un SPSS (version 21) a été utilisé pour l'analyse. Résultats de l'étude: Les résultats ont révélé que la majorité (82,9%) des répondants était entièrement immunisée et que 98% avaient des connaissances sur la vaccination. La majorité des répondants (85,6%) étaient issus de familles fonctionnelles. La fonctionnalité de la famille était statistiquement significative sur le statut vaccinal (X2 = 101,694, P = 0,000) ainsi que sur certaines composantes de la structure familiale: type de famille (P = 0,000), taille de la famille (P = 0,000), groupe ethnique (P = 0,000), et nombre d'enfants (P = 0,000)Conclusion: Les répondants avaient une connaissance adéquate de la vaccination. De plus, la fonctionnalité familiale et la structure familiale influencent le statut vaccinal des nourrissons. Par conséquent, d'autres études devraient être menées sur l'influence de la fonctionnalité et de la structure de la famille sur le statut vaccinal en utilisant une approche multicentrique. Mots-clés: Immunisation, fonctionnalité familiale, structure familiale, vaccine

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Effect of oral 25% dextrose on pain relief in newborn infants undergoing venepuncture

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20201149 ◽

2020 ◽

Vol 7 (4) ◽

pp. 891

Author(s):

H. N. Yashwanth Raju ◽

Rudrappa Sudha ◽

Shwetha B. N.

Keyword(s):

Heart Rate ◽

Pain Relief ◽

Pain Score ◽

Gestational Age ◽

Perinatal Asphyxia ◽

Newborn Infants ◽

Blood Sampling ◽

Clinical Indication ◽

P Value ◽

Medical College

Background: Aim of this study was to study effect of oral 25% dextrose for pain relief in newborns undergoing venepuncture.Methods: This is a case control study conducted in NICU, Cheluvamba hospital attached to Mysore medical college and research institute during the period between September 2018 to November 2018. Babies with gestational age between 34 to 40 weeks of gestation who had clinical indication for blood sampling were included in the study. Neonates who are critically ill, suffered perinatal asphyxia and having congenital anomalies were excluded from the study. Hundred newborn babies admitted to NICU who had clinical indication for blood sampling were enrolled in the study. Study population were divided into 2 groups, dextrose (cases) and non-dextrose group (controls). The data analysis included gestational age, postnatal age, weight, sex, heart rate, oxygen saturation, crying time and behavioural pain assessment.Results: Mean pain score, crying time and heart rate at 5 minutes of venepuncture were studied in both the groups. Mean pain score in dextrose group was 2.68 and in non-dextrose group was 7.18 with significant p value of 0.0062. Mean crying time in dextrose group was 8.98 minutes and in non-dextrose group was 42 minutes with significant p value of 0.001. Mean heart rate in dextrose group was 142 beats/minute and in non-dextrose group was 146bpm with p value of 0.08.Conclusions: Pain in the newborns should be recognised and adequately treated. Lingual 25% dextrose can be used as safe and effective analgesia in neonates undergoing minor invasive procedures like venepuncture.

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Neonatal Hypo-Ketotic Hypoglycemia Secondary to Transient Hyperinsulinism: Diazoxide Responsiveness and Experience With Fasting Test After Treatment Withdrawal

Journal of the Endocrine Society ◽

10.1210/jendso/bvab048.924 ◽

2021 ◽

Vol 5 (Supplement_1) ◽

pp. A452-A453

Author(s):

Nerea Itza Martín ◽

Luis Salamanca Fresno ◽

Cristina Mora Palma ◽

Miguel Saenz De Pipaon Marcos ◽

Isabel Gonzalez Casado ◽

...

Keyword(s):

Gestational Age ◽

Early Recognition ◽

Perinatal Asphyxia ◽

Stress Factors ◽

Treatment Withdrawal ◽

Large For Gestational Age ◽

Congenital Hyperinsulinism ◽

Glucagon Test ◽

Fasting Test ◽

Ketotic Hypoglycemia

Abstract Introduction:: Transient neonatal hyperinsulinism (TNH) is frequently reported in neonates with stress factors (intrauterine growth restriction (IUGR), large for gestational age (LGA), perinatal asphyxia, infants of diabetic mother, etc.). Early recognition and treatment are prioritary to avoid neurological morbidity. Objective: Clinical, molecular characterization and treatment response in neonates with hypoglycemia due to transient hyperinsulinism admitted to a tertiary hospital Neonatal Unit from January 2015 to August 2020. Materials and Methods: Prospective cohort study. Newborns older than 7 days of age, with diagnostic criteria of hyperinsulinism: non ketotic hypoglycemia with detectable insulin, low free fatty acids, glucose infusion rate > 10mg/kg/min, and positive response to glucagon test, were recruited. Results: Out of 5374 patients admitted, 46 (0.85%) presented hypoglycemia secondary to TNH (57% males and 43% females). 78% were delivered by Cesarean section, 59% were European, 17% Latino-Americans, 11% Asians, 9% Africans, and 4% Arabs. 78% were preterm newborns (median 33 weeks gestational age), 70% had birth weights or heights <-1.6 SDS (medians: -1.8 SDS and -2 SDS, respectively). Median age at diagnosis was 22 days (IQE 10–29 days), and feeding was exclusively enteral. Median blood glucose at diagnosis was 37mg/dl (IQE 31-44mg/dl), median insulin: 3mu/ml, median ketonemia: 0.2mmol/L, GH: 15 ng/ml, Cortisol: 16 ug/dl and AAL: 75mg/dl. 90% received diazoxide (dose ranged between 5-10mg/kg/day), presenting as most prevalent side effects hypertrichosis (80%) and edema (13%). Diazoxide median treatment duration was 83 days (IQE 41–110). Response was positive in 100%, with fasting tests response yielding a glycemia > 60mg / dl after 10 hours of fasting post treatment withdrawal. Molecular analysis was carried out with help of a custom NGS panel (MonDIAB.V3; 385 genes) in 80% of the patients. No mutations were identified in known genes implicated in the etiology of congenital hyperinsulinism (ABCC8, KCNJ11, HNF4A, GLUD1, HADH, SLC16A1, GCK, UCP2, HNF1A, AKT2, INSR, CACNA1D), however, predicted deleterious variants were found in other candidate genes such as G6PC2, TH, PMM2, and APPL1, implicated in insulin secretion or glycemic homeostasis. Conclusions: TNH is a prevalent entity to be considered in neonates with risk factors. In our series, TNH is also present in term newborns (22% of patients) and in newborns with weight and/or height appropriate for gestational age (30%). Treatment with diazoxide at low doses is effective in the resolution of these hypoglycemias. The fasting test could be useful for a safe treatment withdrawal when resolution is suspected. No monogenic cause explaining the TNH was identified. Most of the cases molecularly examined presented with 2 or more predicted deleterious variants, suggesting a multifactorial genetic component.

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Intrauterine fetal demise: a retrospective study in tertiary care center in India

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20182962 ◽

2018 ◽

Vol 7 (8) ◽

pp. 3069

Author(s):

Anand Karale ◽

Kunaal K. Shinde ◽

Hemant Damle

Keyword(s):

Gestational Age ◽

Maternal Age ◽

Care Center ◽

Tertiary Care ◽

Mode Of Delivery ◽

P Value ◽

Maternal Complications ◽

Fetal Demise ◽

Maternal Risk ◽

Intrauterine Fetal Demise

Background: An Intrauterine Fetal Demise (IUFD) is a major obstetrical catastrophe at any gestational age but the emotional pain and distress caused by this event increases in direct relation to the duration of pregnancy. The objective of the present study was to determine the incidence and possible causes of Intrauterine Fetal Demise (IUFD), and to determine preventive measures.Methods: Retrospective observational study was done from Jan 2015 to Dec 2017 at Smt. Kashibai Navale Medical College and General Hospital, Narhe, Pune. Inclusion criteria were all the pregnant women with IUFD delivered at the centre, at or above 24 weeks of gestation. The methodology followed were parameters of assessment for analysis were maternal age, parity, probable causes for IUFD, booked or unbooked cases, mode of delivery, maternal complications, and placental histopathology. Statistical data were analyzed using SPSS version 25.Results: The incidence of IUFD at authors’ hospital was 27/1000 live births. The IUFD rate was similar in maternal age <20years and >30years (p value 0.26). The incidence of IUFD increased with decreasing gestational age which was statistically significant (p value 0.001). IUFD incidence was higher in multiparous women compared to primiparous women (p value 0.036 with OR of 1.6 and 95% CI 1.02 to 2.54). The rate of IUFD was similar when sex of the baby was analyzed. 49.4% of fetuses had signs of maceration. The major cause of IUFD was severe preeclampsia (48.1%) which included HELLP syndrome, IUGR, Abruption. Maternal anemia (20.4%), GDM (3.8%), SLE (2.5%), APLA positive (2.5%), anhydramnios (6.3%) were some of the other important causes of IUFD.Conclusions: This study was conducted to determine the incidence of IUFD and associated maternal risk factors. By understanding the contributing factors, we can seek ways of avoiding recurrence of IUFD by proper antenatal care and early diagnosis of obstetric complications and its appropriate management.

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Correlation of neonatal gestational age with foot length and right nipple to umbilicus distance

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20202141 ◽

2020 ◽

Vol 7 (6) ◽

pp. 1319

Author(s):

Ajay K. Keshwani ◽

Swati S. Suroshe

Keyword(s):

Birth Weight ◽

Gestational Age ◽

Tertiary Care ◽

Large For Gestational Age ◽

P Value ◽

Care Hospital ◽

Cross Sectional ◽

Systematic Analysis ◽

Neonatal Deaths ◽

Foot Length

Background: India contributes to one fifth of global live births and more than a quarter of neonatal deaths. A systematic analysis of global, regional and national causes of child mortality in 2013 identified preterm birth complications and infections to be the two major causes of neonatal deaths in India. So, there is need of a simple, easy to use and reliable screening tool for assessment of gestational age at peripheral level for early referral of a neonate to a tertiary care hospital, thereby reducing neonatal mortality.Methods: A hospital based observational cross-sectional study included 350 live new-borns within 48 hours of birth, from September 2018 to February 2019. Gestational age assessed by new ballard score, birth weight, foot length and right nipple to umbilicus distance were noted. Babies categorised as per the gestational age profile as small, appropriate and large for gestational age using fenton charts. Data analysis done, correlation coefficient, and p value calculated to obtain results.Results: Out of 350 babies, males (185) outnumbered females (165); 154 were LBW, 89 VLBW and 76 were ELBW. AGA neonates were 193, and 157 belonged to SGA. There were no post-term and large for gestational age newborns. Both foot length and right nipple to umbilicus distance correlated well with gestational age in all age groups (p<0.001).Conclusions: Foot length as well as right nipple to umbilicus distance can be used as a reliable tool for assessment of gestational age and birth weight of newborns by any health care professional to identify and refer high risk neonate.

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Does Birthweight Represent Imprinting for Life? Preliminary Findings from the Level and Timing of Diabetic Hyperglycemia in Utero: Transgenerational Effect on Adult Morbidity (TEAM) Study

Reports ◽

10.3390/reports3040036 ◽

2020 ◽

Vol 3 (4) ◽

pp. 36

Author(s):

Jane C. Khoury ◽

Mekibib Altaye ◽

Shelley Ehrlich ◽

Suzanne Summer ◽

Nicholas J. Ollberding ◽

...

Keyword(s):

Birth Weight ◽

Gestational Diabetes ◽

Gestational Age ◽

Medical Center ◽

In Utero ◽

Clinic Visit ◽

High Rate ◽

Large For Gestational Age ◽

Obesity Status ◽

To Come

Women with pre-gestational diabetes have a high rate of large for gestational age (LGA) babies compared to women without diabetes. In particular, there is a high rate of asymmetric LGA defined as ponderal index (PI) > 90th percentile for gestational age. We examined the association of birth weight and PI, with body mass index (BMI) and obesity status in adulthood, in a cohort of offspring of women with pre-gestational diabetes. The women participated in the Diabetes in Pregnancy (DiP) study at the University of Cincinnati from 1978 to 1995. The offspring of these women are the cohort participating in an observational study being conducted at Cincinnati Children’s Hospital Medical Center. Once located, the offspring were invited to come in for a one-day clinic visit to assess anthropometrics, and their metabolic, renal and cardiovascular status. Linear and logistic regression was used to assess the association between birth weight and PI with current BMI. We report on 107 offspring. A statistically significant association was found between offspring current BMI with birth PI (β = 1.89, 95% CI 0.40–3.38), and between offspring current obesity status and birth asymmetric LGA (aOR = 2.44, 95% CI 1.01–5.82). This is consistent with in utero “metabolic programming”.

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Human Milk Virome Analysis: Changing Pattern Regarding Mode of Delivery, Birth Weight, and Lactational Stage

Nutrients ◽

10.3390/nu13061779 ◽

2021 ◽

Vol 13 (6) ◽

pp. 1779

Author(s):

Meltem Dinleyici ◽

Vicente Pérez-Brocal ◽

Sertac Arslanoglu ◽

Ozge Aydemir ◽

Sibel Sevuk Ozumut ◽

...

Keyword(s):

Birth Weight ◽

Human Milk ◽

Vaginal Delivery ◽

Gestational Age ◽

Small For Gestational Age ◽

Mode Of Delivery ◽

Large For Gestational Age ◽

Delivery Mode ◽

Age Group ◽

Spontaneous Vaginal Delivery

The human milk (HM) microbiota is a significant source of microbes that colonize the infant gut early in life. The aim of this study was to compare transient and mature HM virome compositions, and also possible changes related to the mode of delivery, gestational age, and weight for gestational age. Overall, in the 81 samples analyzed in this study, reads matching bacteriophages accounted for 79.5% (mainly Podoviridae, Myoviridae, and Siphoviridae) of the reads, far more abundant than those classified as eukaryotic viruses (20.5%, mainly Herpesviridae). In the whole study group of transient human milk, the most abundant families were Podoviridae and Myoviridae. In mature human milk, Podoviridae decreased, and Siphoviridae became the most abundant family. Bacteriophages were predominant in transient HM samples (98.4% in the normal spontaneous vaginal delivery group, 92.1% in the premature group, 89.9% in the C-section group, and 68.3% in the large for gestational age group), except in the small for gestational age group (only ~45% bacteriophages in transient HM samples). Bacteriophages were also predominant in mature HM; however, they were lower in mature HM than in transient HM (71.7% in the normal spontaneous vaginal delivery group, 60.8% in the C-section group, 56% in the premature group, and 80.6% in the large for gestational age group). Bacteriophages still represented 45% of mature HM in the small for gestational age group. In the transient HM of the normal spontaneous vaginal delivery group, the most abundant family was Podoviridae; however, in mature HM, Podoviridae became less prominent than Siphoviridae. Myoviridae was predominant in both transient and mature HM in the premature group (all C-section), and Podoviridae was predominant in transient HM, while Siphoviridae and Herpesviridae were predominant in mature HM. In the small for gestational age group, the most abundant taxa in transient HM were the family Herpesviridae and a species of the genus Roseolovirus. Bacteriophages constituted the major component of the HM virome, and we showed changes regarding the lactation period, preterm birth, delivery mode, and birth weight. Early in life, the HM virome may influence the composition of an infant’s gut microbiome, which could have short- and long-term health implications. Further longitudinal mother–newborn pair studies are required to understand the effects of these variations on the composition of the HM and the infant gut virome.

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Morbidity Pattern and Hospital Outcome of Neonates Admitted in Tertiary Care Hospital, Nepal

Journal of Nepal Paediatric Society ◽

10.3126/jnps.v40i2.29469 ◽

2020 ◽

Vol 40 (2) ◽

pp. 107-113

Author(s):

Deepeshwara Nepal ◽

Sumit Agrawal ◽

Sushan Shrestha ◽

Ajit Rayamajhi

Keyword(s):

Birth Weight ◽

Perinatal Asphyxia ◽

Tertiary Care ◽

Mode Of Delivery ◽

Birth Asphyxia ◽

Extremely Low Birth Weight ◽

P Value ◽

Care Hospital ◽

Hospital Outcome ◽

Poor Outcome

Introduction: The first 28 days of life, neonatal period is crucial as neonates are susceptible to sepsis, birth asphyxia, hypoxic injuries and its consequences which may lead to lifelong morbidity. Knowing the causes of morbidity and mortality is an essential step to improve neonatal health. The aim of this study is to describe the pattern and causes of neonatal admission, immediate hospital outcome in the form of improved, died or left against medical advice and factors associated with its outcome. Methods: This was a retrospective hospital based study carried out in Neonatal Intensive Care Unit (NICU) of Kanti Children’s Hospital, Kathmandu, Nepal over a period of six months (February 2019 to July 2019 AD). Neonatal details including age, sex, gestational age, birth weight, and maternal age and parity, mode of delivery, place of delivery, neonatal morbidities and neonatal outcomes were recorded in a predesigned performa. Results were expressed as mean, percentage and p value. P- value was calculated by using chi-square test. Results: A total of 163 neonates were admitted during the study period, among which 106 (65%) were males. The mean birth weight was 2483.96 ± 812.63 gm. Among admitted newborns 130 (79.8%) had good outcome, babies born to young mothers (< 20 years of age) had poor outcome which is statistically significant with p value of 0.002. Neonates whose birth weight were < 1000 gram had significantly poor outcome (0.001). Conclusion: Common causes of NICU admission were neonatal sepsis, neonatal hyperbilirubinemia, prematurity and perinatal asphyxia. Babies born to young primipara mothers, extremely low birth weight, extremely premature babies and babies undergoing mechanical ventilation had poor outcome.

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FETOMATERNAL OUTCOME IN POST DATED PREGNANCY: A RETROSPECTIVE STUDY

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v4i6.1168 ◽

2020 ◽

Vol 4 (6) ◽

Author(s):

Sudesh Agrawal ◽

Angurbala Patidar ◽

Satish Kumar

Keyword(s):

Pregnant Women ◽

Gestational Age ◽

Maternal Morbidity ◽

Perinatal Death ◽

Mode Of Delivery ◽

Fetal Distress ◽

P Value ◽

Term Pregnancy ◽

Gestational Length ◽

Post Term Pregnancy

Introduction: Postdated pregnancy is defined as pregnancy extended beyond 40 weeks of gestation or 280 days. FIGO and WHO defined post term pregnancy as a pregnancy which has gestational length of 294 days or more, Post term pregnancy is defined as pregnancy that has extended to or beyond 42 weeks of gestation, or estimated date of delivery (EDD)+14 days. Therefore we conducted this study to evaluate fetomaternal outcome in post dated pregnancies. Material & Methods: This was a retrospective hospital based study conducted on 400 pregnant women beyond 40 weeks of gestational age from the period of November 2018 to October 2019. A detailed history and clinical examination were recorded in performa from hospital records. Data pertaining to the onset of labour, mode of delivery, caesarean section due to fetal distress/ meconium stained liquor birth weight, Apgar score at 1minute and 5minute,NICU admission and perinatal death were analysed. The data obtained were entered in Microsoft excel and were analysed using appropriate statistical test (chi square test). P value of <0.05 was taken as significant. Results: Majority of cases belonged to rural area where total 57.3% cases were found while 171(42.7%) cases belonged to urban area. 184(46%) cases were booked and 216(54%) cases were unbooked. 260(65%) cases were referred from other centers, 140(35%) cases were not referred. 253(63.3%) cases were primigravida, 87(21.8%) cases were second gravida and 14.9% cases were multigravida.As a induction of labour oxytocin was used in 126(31.5%)cases, CP gel was used in 73(18.3%) of cases while miso was used in 26(6.5%) of cases. Conclusion: Maternal morbidity increased in the form of emergency LSCS, postpartum hemorrhage, instrumental deliveries, as the gestational age increased beyond 40 weeks. Maternal and fetal morbidity and mortality can be reduced by electively inducing pregnant women at 40 weeks as allowing them to continue beyond this gestational age has shown adverse feto-maternal outcomes. Keywords: Fetomaternal, LSCS, Maternal Morbidity

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