scholarly journals Lipid Profile of Healthy Women During Normal Pregnancy

2009 ◽  
Vol 28 (3) ◽  
pp. 152-160 ◽  
Author(s):  
Margarita Diareme ◽  
Petros Karkalousos ◽  
Georgos Theodoropoulos ◽  
Stefanos Strouzas ◽  
Nikos Lazanas
Keyword(s):  
Pregnant Women ◽  
Lipid Profile ◽  
Gestational Age ◽  
First Trimester ◽  
Normal Pregnancy ◽  
Second Trimester ◽  
Third Trimester ◽  
Predisposing Factor ◽  
Healthy Women ◽  
C 30

Lipid Profile of Healthy Women During Normal PregnancyThe four basic lipid indexes (Chol, Trig, HDL-C and LDL-C) increase during pregnancy, following different rates of increase. Among the four analytes triglycerides show the largest increase and HDL-C the smallest. All analyte values are raised during the 40 weeks of pregnancy, except HDL-C which is stabilized during the second trimester. After delivery the values decrease, except LDL-C which remains steady (for some weeks) before starting to fall following the others. In this study the relations between the four lipid indexes and some predisposing factors (age, gestational age, nationality, body mass index, profession, smoking and diabetes during pregnancy) were investigated. The sample consisted of 413 pregnant women, mainly Greeks and Albanians. After regression analysis it was proved that the only common predisposing factor was the gestational age. Triglycerides and total cholesterol are also influenced by the women's age. The lipid indexes showed no important difference between the pregnant women in the first trimester and the non-pregnant women. On the contrary, there was a statistical difference between the pregnant women in the second and third trimester and between them and the women in the first trimester. The percentages of increase between first and second trimester were: Chol: 38%, Trig: 115%, HDL-C: 30%, LDL-C: 33%. The percentages of increase between first and third trimester were: Chol: 65%, Trig: 208%, HDL-C: 26%, LDLC: 64%.

scholarly journals Maternal Serum Levels of Alpha Tumour Necrotic Factor, Interleukin 10, Interleukin 6 and Interleukin 4 in Malaria Infected Pregnant Women Based on Their Gestational Age in Southeast, Nigeria

2020 ◽  
pp. 64-70
Author(s):  
Obeagu, Emmanuel Ifeanyi ◽  
Esimai, Bessie Nonyelum ◽  
Ekelozie, Ifeoma Stella ◽  
Asogwa Eucharia Ijego ◽  
Amaeze Augustine Amaeze ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
First Trimester ◽  
Interleukin 10 ◽  
Interleukin 4 ◽  
Second Trimester ◽  
Third Trimester ◽  
Tnf Α ◽  
Significant Difference ◽  
Tumour Necrotic Factor

Malaria has been reported as a condition caused by infestation with Plasmodium parasite species, is a major public health problem globally especially in developing countries like Nigeria. This study was carried out in Federal Medical Centre Umuahia in Abia State, Nigeria. A study was done to determine the maternal serumlevels of alpha tumour necrotic factor, interleukin 10, interleukin 6and interleukin 4 in malaria infected pregnant women based on their gestational age in Southeast, Nigeria. A total of 150 subjects between the ages of 18-45 years were recruited for the study comprising of fifty (50) subjects each of the 3 trimesters. Commercial ELISA Kit by MELSIN Medical Co Limited was used to measure all the cytokines. The results of Table 1 showed no significant difference of TNF-α (p=0.346), IL-10 (p=0.059), IL-6 (p=0.811) and IL-4 (p=0.257) of malaria infected pregnant women at first trimester and second trimester respectively. The results of Table 2 showed no significant difference of TNF-α (p=0.642), IL-10 (p=0.678), IL-6 (p=0.551) and IL-4 (p=0.280) of malaria infected pregnant women at first trimester and third trimester respectively. The results of Table 2 showed no significant difference of TNF-α (p=0.062), IL-10 (p=0.016), IL-6 (p=0.352) and IL-4 (p=0.914) of malaria infected pregnant women at first trimester and third trimester respectively. The study showed no changes in the cytokines studied among the malaria infected pregnant women based on gestational ages except when IL-10 was compared between the subjects on second trimester and third trimester. This study shows that malaria infection does not changes these cytokines in pregnant women based on gestational ages except the il-10 when compared at second trimester and third trimester but changes when compared at other trimesters.

scholarly journals The course of ankylosing spondylitis during pregnancy: intermediate data of a prospective follow-up

2019 ◽  
Vol 13 (2) ◽  
pp. 61-72 ◽  
Author(s):  
O. A. Krichevskaya ◽  
Z. M. Gandaloeva ◽  
A. B. Demina ◽  
T. V. Dubinina
Keyword(s):  
Back Pain ◽  
Ankylosing Spondylitis ◽  
Disease Activity ◽  
Pregnant Women ◽  
Functional Status ◽  
Gestational Age ◽  
First Trimester ◽  
Second Trimester ◽  
Third Trimester ◽  
The Third

The onset of ankylosing spondylitis (AS) more frequently occurs at the end of the third decade of life, which corresponds to the time of marriage and the birth of the first child and determines the relevance of a study of the interaction of AS and pregnancy.Objective: to describe the clinical presentations of AS and its therapy during pregnancy and to study AS activity dynamics and the patients' functional status during gestation.Patients and methods. The investigation enrolled 19 pregnant women who met the 1984 modified New York AS criteria. The mean age of the women was 32.2±1.1 years; their mean age at the onset of AS was 22.6±3.1 years; the duration of the disease was 147±20.7 months. The patients visited their physician at 10–11, 20–21, and 31–32 weeks of pregnancy. The investigators determined AS activity by the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and the Ankylosing Spondylitis Disease Activity Score (ASDAS) and functional status by the Bath Ankylosing Spondylitis Functional Index (BASFI) and the Bath Ankylosing Spondylitis Metrology Index (BASMI). The Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) was used to assess enthesitis.Results and discussion. At the time of conception, 78.9% of the patients had inflammatory back pain with an intensity of 2.2±0.4 on a numerical rating scale; during pregnancy, 95% of the pregnant women experienced pain, its intensity increased by the second trimester (4.6±0.7) and remained at this level in the third trimester (p<0.05 between the month of conception and the second and third trimesters). By the third trimester, the nature of the pain changed: 55.5 and 61.1% of the patients reported reduced pain at rest and after exercise, respectively. The frequency and severity of enthesitis increased with gestational age: the MASES scores were higher in the third trimester (2.3±0.5) than that in the first-trimester (0.4±0.22; p<0.05). The frequency of extra-axial and extra-skeletal manifestations did not increase during gestation. Coxitis was detected in 27.8% of the pregnant women.The BASDAI increased from the time of conception (1.7±0.3) to the second trimester (3.3±0.5; p<0.05) and remained at this level in the third trimester. Multiple regression analysis revealed that the predictors of BASDAI levels in the third trimester were BASDAI scores (R2 =0.7) and back pain (R2 =0.9) at the time of conception, the use of biological agents 3 months before gestation (R2 =0.7) with their cumulative impact. Throughout pregnancy, the BASDAI was determined by a set of factors: the severity of pain in the back (β=0.6) and entheses (β=0.3) and weakness (β=0.6). By the end of the first trimester, the increased BASDAI scores were provided mainly by the higher level of general weakness (by 68.5%) and back pain (by 24.1%). In the second trimester, the higher BASDAI was due to the increased severity of enthesitis (by 30.7%) and back pain (by 27%).There were no changes in ASDAS-C-reactive protein (ASDAS-CRP), but there was its upward tendency in the second trimester as compared with the beginning of pregnancy. The BASMI did not change significantly (1.3±0.9; 1.8±0.2; 2.1±0.3, respectively, for trimesters). The BASFI increased by the third trimester (3.9±0.7) versus the first trimester (1.4±0.3; p<0.05).In the third trimester, this rise was due to difficulties in performing the actions related to both AS activity and pregnancy (forward bends; questions 1, 2, and 4).According to the trimesters, 31.6, 73.7, and 66.7% of the pregnant women took nonsteroidal anti-inflammatory drugs. The need for glucocorticoids was noted in 22% of patients in the second trimester and in 53% in the third trimester.Conclusion. The clinical activity of AS is increased by the second trimester of pregnancy and remains moderate and high until the end of gestation. The activity of AS at the time of conception can determine the activity of the disease throughout pregnancy. In the third trimester, mechanical back pain becomes concurrent in half of the patients. Functional impairments increase with gestational age, and this is due to both the activity of AS and pregnancy itself in the third trimester. 

Thrombin generation, D-dimer and protein S in uncomplicated pregnancy

2015 ◽  
Vol 53 (12) ◽  
Author(s):  
Mirjana K. Kovac ◽  
Sanja Z. Lalic-Cosic ◽  
Jelena M. Dmitrovic ◽  
Valentina J. Djordjevic ◽  
Dragica P. Radojkovic
Keyword(s):  
Pregnant Women ◽  
Reference Values ◽  
Gestational Age ◽  
Protein S ◽  
First Trimester ◽  
Second Trimester ◽  
Third Trimester ◽  
The Third ◽  
D Dimer ◽  
Protein S Activity

AbstractGestational age-specific reference values are essential for the accurate interpretation of haemostatic tests during pregnancy.Our 1-year prospective study included 40 healthy pregnant women with a median age of 30 (range 22–40) years; the subjects were followed in order to establish the gestational age dependent values for endogenous thrombin potential (ETP), D-dimer and protein S (activity and free).During the first trimester 50% of studied women had ETP >100% (reference values out of pregnancy); in the second trimester an ETP over 100% was observed in all women; ETP values remained unchanged during the third trimester. In the first trimester, the median D-dimer concentration of 0.30 mg/L, in the second 0.91 mg/L and in the third of 1.45 mg/L were observed. During the first trimester 14/40 subjects had protein S activity below reference range (<59%, out of pregnancy); the median value of 61.35; interquartile range (IQR) 20.38; in the second 21/37; the median value of 53.1 (IQR 15.65); in the third trimester 28/37 had low level of protein S activity with the median value of 49.0 (IQR 18.8). Free protein S showed a slight decrease from the first trimester; it remained almost stable during the rest of pregnancy, with the equal number of pregnant women with reduced free protein S.Related to the gestational age, a significant increase of ETP and D-dimer, from the second trimester was observed; the decrease of protein S was observed already from the early pregnancy, with more pronounced variability of protein S activity.

scholarly journals Evaluation Serum Copper Levels in Preeclampsia and Healthy Pregnant Women

2019 ◽  
Vol 9 (1) ◽  
pp. 18-22
Author(s):  
Nilima Baral ◽  
Rezwana Haque ◽  
Farzana Akonjee Mishu
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Normal Pregnancy ◽  
Serum Copper ◽  
Copper Level ◽  
Control Group ◽  
Case Group ◽  
Second Trimester ◽  
Serum Copper Level ◽  
Third Trimester

Background: Preeclampsia is a fatal medical disorder of pregnancy. It has been associated with adverse course and outcome of the pregnancy resulting in increased maternal and infant mortality and morbidity. As the pathogenesis of preeclampsia is not completely understood, prevention remains a complex issue. In recent times, there has been an increasing prevalence in the incidence of preeclampsia globally. The aim of this study is to determine the states of the copper in pregnant women with preeclampsia. Methods: This case-control study was carried out in the Department of Biochemistry, Mymensingh Medical College, Mymensingh, from July 2013 to June 2014. The subjects were selected on the basis of inclusion and exclusion criteria by purposive method. This study included 73 patients with preeclampsia as case (Gr.I) classified into two subgroups according to the gestational age: Gr.I(a); preeclampsia in the second trimester (n = 35), and Gr.I(b); preeclampsia in the third trimester (n = 38). Copper levels were analyzed and results were compared with 73 apparently healthy pregnant control (Gr.II), and the corresponding gestational age subgroups [Gr.II(a); normal pregnancy of second trimester (n = 35) and Gr.II(b), normal pregnancy of third trimester (n = 38)]. Results: The mean serum copper level was significantly (p<0.001) lower in case group than that of control group. Similar extent of reduction was observed in serum copper level at different gestational age groups of preeclamptic women when compared with corresponding control groups. Conclusion: Estimation of serum copper level should be incorporated in pre eclamptic patients for prevention of complications. Birdem Med J 2019; 9(1): 18-22

Gestational age-specific reference intervals for 15 biochemical measurands during normal pregnancy in China

2017 ◽  
Vol 55 (4) ◽  
pp. 446-452 ◽  
Author(s):  
Yanpeng Dai ◽  
Junjie Liu ◽  
Enwu Yuan ◽  
Yushan Li ◽  
Quanxian Wang ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Gestational Age ◽  
Parametric Method ◽  
First Trimester ◽  
Normal Pregnancy ◽  
Reference Intervals ◽  
Specific Reference ◽  
Gamma Glutamyl Transpeptidase ◽  
Cross Sectional ◽  
Laboratory Results

Aims Physiological changes that occur during pregnancy can influence biochemical parameters. Therefore, using reference intervals based on specimens from non-pregnant women to interpret laboratory results during pregnancy may be inappropriate. This study aimed to establish the essential reference intervals for a range of analytes during pregnancy. Methods A cross-sectional study was performed in 13,656 healthy pregnant and 2634 non-pregnant women. Fifteen biochemical measurands relating to renal and hepatic function were analysed using an Olympus AU5400 analyzer (Olympus, Tokyo, Japan). All the laboratory results were checked for outliers using Dixon’s test. Reference intervals were established using a non-parametric method. Results Alanine aminotransferase, aspartate aminotransferase, albumin, cholinesterase, creatinine, direct bilirubin, gamma-glutamyl transpeptidase, total bilirubin, total bile acid and total protein showed a decrease during the whole gestational period, while alkaline phosphatase and uric acid increased. Urea nitrogen, β2-microglobulin and cystatin-C fell significantly during the first trimester and then remained relatively stable until third trimester. Reference intervals of all the measurands during normal pregnancy have been established. Conclusions The reference intervals established here can be adopted in other clinical laboratories after appropriate validation. We verified the importance, for some measurands, of partitioning by gestational age when establishing reference intervals during pregnancy.

scholarly journals Thrombin Generation in Chinese Pregnant Women and the Effect of Insulin Use on Thrombin Generation in Patients with GDM

2019 ◽  
Vol 25 ◽  
pp. 107602961986349
Author(s):  
Feng Dong ◽  
Longhao Wang ◽  
Chengbin Wang
Keyword(s):  
Blood Glucose ◽  
Pregnant Women ◽  
Thrombin Generation ◽  
First Trimester ◽  
Normal Pregnancy ◽  
Third Trimester ◽  
Control Blood Glucose ◽  
Normal Ranges ◽  
Increased Risk ◽  
Significant Difference

Pregnancy is a hypercoagulable state associated with an increased risk of venous thrombosis. Calibrated automated thrombogram (CAT) is a test to monitor the thrombin generation (TG), a laboratory marker of thrombosis risk, and increases during normal pregnancy, but it is still unclear whether TG is related to the use of insulin in pregnant women with gestational diabetes mellitus (GDM). We performed thrombin generation by CAT on 135 normal pregnant women, including 43 in first trimester, 32 in second trimester, 60 in third trimester, respectively; 68 pregnant women with GDM were also enrolled, 19 patients with GDM using insulin to control blood glucose and 49 patients control their blood glucose through diet and exercise with noninsulin treatment. The overall CAT parameters were calculated using descriptive statistics method with mean ± standard deviation. Mean endogenous thrombin potential, peak thrombin generation, and StartTail time increased significantly with the pregnancy. There was no significant difference in TG test parameters except StartTail time( P = .003) in insulin-treated GDM group when compared to those without insulin in the GDM group. The normal ranges for CAT parameters in pregnant women were determined. Thrombin generation increased significantly in first trimester and remains stable in second and third trimester. The use of insulin in patient with GDM did not affect thrombin generation test. Our study helps to establish the reference range of thrombin generation in Chinese normal pregnant population and provide more basis to predict the risk of thrombus complicating during pregnancy.

Gestation specific reference intervals for thyroid function tests in pregnancy

2016 ◽  
Vol 54 (8) ◽  
Author(s):  
Süleyman Akarsu ◽  
Filiz Akbiyik ◽  
Eda Karaismailoglu ◽  
Zeliha Gunnur Dikmen
Keyword(s):  
Pregnant Women ◽  
Thyroid Function ◽  
First Trimester ◽  
Reference Intervals ◽  
Specific Reference ◽  
Thyroid Function Tests ◽  
Second Trimester ◽  
Third Trimester ◽  
The Third ◽  
Function Tests

AbstractThyroid function tests are frequently assessed during pregnancy to evaluate thyroid dysfunction or to monitor pre-existing thyroid disease. However, using non-pregnant reference intervals can lead to misclassification. International guidelines recommended that institutions should calculate their own pregnancy-specific reference intervals for free thyroxine (FT4), free triiodothyronine (FT3) and thyroid-stimulating hormone (TSH). The objective of this study is to establish gestation-specific reference intervals (GRIs) for thyroid function tests in pregnant Turkish women and to compare these with the age-matched non-pregnant women.Serum samples were collected from 220 non-pregnant women (age: 18–48), and 2460 pregnant women (age: 18–45) with 945 (39%) in the first trimester, 1120 (45%) in the second trimester, and 395 (16%) in the third trimester. TSH, FT4 and FT3 were measured using the Abbott Architect i2000SR analyzer.GRIs of TSH, FT4 and FT3 for first trimester pregnancies were 0.49–2.33 mIU/L, 10.30–18.11 pmol/L and 3.80–5.81 pmol/L, respectively. GRIs for second trimester pregnancies were 0.51–3.44 mIU/L, 10.30–18.15 pmol/L and 3.69–5.90 pmol/L. GRIs for third trimester pregnancies were 0.58–4.31 mIU/L, 10.30–17.89 pmol/L and 3.67–5.81 pmol/L. GRIs for TSH, FT4 and FT3 were different from non-pregnant normal reference intervals.TSH levels showed an increasing trend from the first trimester to the third trimester, whereas both FT4 and FT3 levels were uniform throughout gestation. GRIs may help in the diagnosis and appropriate management of thyroid dysfunction during pregnancy which will prevent both maternal and fetal complications.

scholarly journals Indeks DMF-T dan OHIS pada Ibu Hamil

2019 ◽  
Vol 1 (1) ◽  
pp. 12-22
Author(s):  
Applonia Leo Obi
Keyword(s):  
Pregnant Women ◽  
Health Center ◽  
Sampling Technique ◽  
First Trimester ◽  
Second Trimester ◽  
Third Trimester ◽  
High Prevalence ◽  
Second Trimester Pregnancy ◽  
And Behavior ◽  
Descriptive Method

Abstract: DMF-T and OHIS index for pregnant women. Pregnancy is a physiological process that causes changes in a woman's body both physically and psychologically. During pregnancy physiological changes occur which are often accompanied by changes in attitude and behavior. The health behavior of pregnant women also has a very big influence on herself and the fetus. This research is a descriptive method. This study aims to determine the rates of DMF-T and OHIS in pregnant women at Oesapa Health Center, Kupang City. Sampling by accidental sampling technique, amounting to 97 pregnant women who visited the MCH polyclinic at the Kupang Oesapa Health Center. The results based on DMF-T figures show that the high prevalence of dental caries in the second-trimester pregnant women group (36.0%) than in the third trimester of pregnancy (28.8%) while OHIS most respondents in the second-trimester pregnancy (36, 1%) had an OHI-S index in the medium category with a ratio of trimester 3 there were 23 people (23.7%) and first trimester around 19 people (19.6%). It was concluded that the DMF-T index of pregnant women in the working area of ​​the Kupang City Oesapa health center was mostly carious and most of the pregnant women examined had caries of more than 4 teeth per person and all pregnant women who were examined for dental and oral hygiene levels showed moderate criteria. Abstrak: Indeks DMF-T dan OHIS pada Ibu Hamil. Kehamilan merupakan suatu proses fisiologis yang menimbulkan perubahan pada tubuh wanita baik fisik maupun psikis. Pada masa kehamilan terjadi perubahan fisiologis yang sering disertai dengan perubahan sikap dan perilaku. perilaku  kesehatan  ibu  hamil  juga  memiliki  pengaruh yang  sangat  besar  bagi  dirinya  sendiri  dan  janin. Penelitian ini adalah metode deskriptif. Penelitian ini bertujuan untuk mengetahui  angka DMF-T dan OHIS pada ibu hamil di Puskesmas Oesapa Kota Kupang. Pengambilan sampel dengan teknik accidental sampling, berjumlah 97 ibu hamil yang berkunjung ke poli KIA di Puskesmas Oesapa Kota Kupang. Hasil penelitian berdasarkan Angka DMF-T menunjukkan bahwa tingginya prevalensi karies gigi pada kelompok ibu hamil  trimester kehamilan kedua (36,0%) dari pada trimester kehamilan ke tiga (28,8%) sedangkan OHIS sebagian besar responden pada kehamilan trimester 2 (36,1%) memiliki indek OHI-S pada kategori sedang dengan perbandingan trimester 3 ada 23 orang (23,7%) dan trimester I sekitar 19 orang (19,6%). Disimpulkan bahwa indeks DMF-T ibu hamil diwilayah kerja puskesmas Oesapa Kota Kupang sebagian besar berkaries dan sebagian besar ibu hamil yang diperiksa mempunyai karies lebih dari 4 gigi per orang dan semua ibu hamil yang diperiksa tingkat kebersihan gigi dan mulutnya menunjukkan kriteria sedang.

scholarly journals Inter Trimester Hemoglobin Levels in Pregnant Women

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Bella Andira Safitri
Keyword(s):  
Pregnant Women ◽  
Health Center ◽  
Secondary Data ◽  
First Trimester ◽  
Hemoglobin Level ◽  
Second Trimester ◽  
Third Trimester ◽  
Series Design ◽  
Abnormal Hemoglobin ◽  
Research Criteria

Hemoglobin functions to transport all oxygen from the lungs to the tissue cells. Hemoglobin contains iron and is still present in red blood cells. In pregnant women hemoglobin levels are often abnormal. According to PMK RI No. 97 of 2014 concerning health services, it stipulates that pregnant women are checked for hemoglobin at least once in the first trimester and once in the third trimester. This is done to determine the condition of pregnant women during pregnancy. Low hemoglobin levels cause anemia. Anemia in pregnant women can affect the process of fetal growth and development in the womb. The purpose of this study was to determine the hemoglobin level between trimesters in pregnant women at the Jatilawang Health Center, Banyumas Regency in 2020. The research criteria was a descriptive study using a retrospective time series design using secondary data. The results of inter-trimester hemoglobin levels in pregnant women at the Jatilawang Health Center, Banyumas Regency in 2020 are in the first trimester 40% normal hemoglobin levels and 60% abnormal hemoglobin levels, in the second trimester hemoglobin levels are 72% normal and 28% hemoglobin levels are not normal, in the second trimester the hemoglobin levels are normal and 28% are abnormal. III 96% normal hemoglobin level and 4% abnormal hemoglobin level. Inter-trimester hemoglobin levels in pregnant women at the Jatilawang Health Center, Banyumas Regency in 2020 tend to be higher based on trimesters I, II and III.

scholarly journals Physiological changes in iron and blood parameters during different pregnancy trimesters in pregnant women in Baghdad

2018 ◽  
Vol 29 (1) ◽  
pp. 49
Author(s):  
Marwa Thamir Mohammed
Keyword(s):  
Pregnant Women ◽  
Maternal Education ◽  
Cell Mass ◽  
First Trimester ◽  
Blood Parameters ◽  
Blood Film ◽  
Clear Correlation ◽  
Second Trimester ◽  
Third Trimester ◽  
Examination Result

 SummaryThis work was carried out for four months in the province of Baghdad including many hospital in Bagdad during 1st of the November 2016 until 28 February 2017. 120 pregnant women included in the present study ranged in age from 14 - 42 years were randomly selected. Pregnant women were divided into three groups according to the different periods of pregnancy every trimester include 40 pregnant women divided to 20 pregnant women with anemia and 20 without anemia after taking a blood  film and hemoglobin as a good adoption indicator for diagnosis of anemia, also, history taken by previously diagnosis and by physical examination. Result of the three trimesters in indicators the blood of pregnant women with or without anemia, showed that the first trimester all of the parameters of indicators the blood (Hb, Hct, MCV, MCH and MCHC) were decreased in women with anemia compared with women without anemia, also in second and third trimester decreased. However, in second trimester the values of Hb, Hct, MCV, MCH and MCHC decreased in women with anemia on the values of the first trimester. On the other hand a values of indicators the blood in a third trimester less than the second trimester. Indicator of iron (SI, TIBC, TS and SF) for women with anemia in first trimester was less than from women without anemia. However, in second trimester the values of SI, TIBC, TS and SF decreased in women with anemia on the values of the first trimester. Father more, the values of indicator of iron in a third trimester less than in the second trimester. When comparison in blood parameters (Hb, Hct, MCV, MCH and MCHC) between 1st, 2nd, and 3rd trimester of pregnancy women noticed that the all parameters decreased gradually from the first trimesters to second to third trimester. Iron deficiency marked increase was famous in pregnant women in the second and third trimester of pregnancy, due to high fetal and placenta growth rates and development of red cell mass mother. Thus anemia affects up to 70% of pregnant women. Blood indicators RBC, RDW, platelet and MPV for all pregnant women in the first trimester was decreased in women with anemia compared with women without anemia in all parameters of this, also in second and third trimester. Further more in second decreased from first, also in third less that from second. White blood cell and their various types (NEU, LYM, Mono, ESO and BASO) were impressed with the pregnant women with anemia in first and second trimesters WBC and NEU% increased but LYM%, Mono%, ESO% and BASO% decreased. However, in the third trimester WBC, NEU% and BASO% decreased but LYM%, Mono%, and EOS% increased. The results of the study found out that the is a clear correlation between anemia in pregnant women and some social factors, such as: occupation, monthly income and maternal education.

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