scholarly journals Photothermal/pH Dual-Responsive Drug Delivery System of Amino-Terminated HBP-Modified rGO and the Chemo-Photothermal Therapy on Tumor Cells

2018 ◽  
Vol 13 (1) ◽  
Author(s):  
Wei Zhang ◽  
Jiamu Dai ◽  
Guangyu Zhang ◽  
Yu Zhang ◽  
Suying Li ◽  
...  
2018 ◽  
Vol 6 (7) ◽  
pp. 1011-1017 ◽  
Author(s):  
Tiantian Wu ◽  
Hai Huang ◽  
Yaping Sheng ◽  
Hongdong Shi ◽  
Yuanzeng Min ◽  
...  

The PEGylation of anti-EGFR nanobodies was achieved via a transglutaminase catalyzed reaction through a Q-tag. The nanobody tethered drug delivery system exhibits superior specificity to EGFR positive tumor cells.


2021 ◽  
Vol 16 (7) ◽  
pp. 1029-1036
Author(s):  
Hongzhu Wang ◽  
Mengxun Chen ◽  
Liping Song ◽  
Youju Huang

A key challenge for nanoparticles-based drug delivery system is to achieve manageable drug release in tumour cell. In this study, a versatile system combining photothermal therapy and controllable drug release for tumour cells using temperature-sensitive block copolymer coupled Au NRs@SiO2 is reported. While the Au NRs serve as hyperthermal agent and the mesoporous silica was used to improve the drug loading and decrease biotoxicity. The block copolymer acted as “gatekeeper” to regulate the release of model drug (Doxorubicin hydrochloride, DOX). Through in vivo and in vitro experiments, we achieved the truly controllable drug release and photothermal therapy with the collaborative effect of the three constituents of the nanocomposites. The reported nanocomposites pave the way to high-performance controllable drug release and photothermal therapy system.


2020 ◽  
Vol 324 ◽  
pp. 330-340 ◽  
Author(s):  
Ning Zhao ◽  
Bingbing Ding ◽  
Ying Zhang ◽  
Jessica L. Klockow ◽  
Ken Lau ◽  
...  

2019 ◽  
Vol 7 (24) ◽  
pp. 3811-3825 ◽  
Author(s):  
Panchanathan Manivasagan ◽  
Seung Won Jun ◽  
Van Tu Nguyen ◽  
Nguyen Thanh Phong Truong ◽  
Giang Hoang ◽  
...  

FA–COS–TGA–GNRs–DOX have been successfully designed as a drug delivery system for chemo-photothermal combination therapy.


2015 ◽  
Vol 44 (22) ◽  
pp. 10343-10351 ◽  
Author(s):  
Xijian Liu ◽  
Qilong Ren ◽  
Fanfan Fu ◽  
Rujia Zou ◽  
Qian Wang ◽  
...  

A difunctional nanoplatform (CuS@mSiO2-PEG) acted as a NIR light induced photothermal-triggered drug delivery system for efficient chemo-photothermal therapy.


2016 ◽  
Vol 4 (36) ◽  
pp. 6043-6051 ◽  
Author(s):  
Junling Wang ◽  
Ran Wang ◽  
Fangrong Zhang ◽  
Yajun Yin ◽  
Leixia Mei ◽  
...  

A targeted drug delivery system based on carbon nanohorns for targeting P-glycoprotein and delivering etoposide into cells to overcome multidrug resistance.


2021 ◽  
Vol 9 (01) ◽  
pp. 1056-1057
Author(s):  
M. Lavanya ◽  

In this article, targeted and controlled anticancer drug delivery and release with magneto-electric nanoparticles, published in 2016, rodzinski et al., explain how magneto-electric nanoparticles abbreviated as (mens) can be used to monitor the delivery of drugs and their release into cancer cells. They go further to explain how they use this automated drug delivery system to eradicate cancerous tumor cells.


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